KR102475555B1 - 제어된 환경에서의 연질 캡슐의 가속 건조 - Google Patents

제어된 환경에서의 연질 캡슐의 가속 건조 Download PDF

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Publication number
KR102475555B1
KR102475555B1 KR1020197014547A KR20197014547A KR102475555B1 KR 102475555 B1 KR102475555 B1 KR 102475555B1 KR 1020197014547 A KR1020197014547 A KR 1020197014547A KR 20197014547 A KR20197014547 A KR 20197014547A KR 102475555 B1 KR102475555 B1 KR 102475555B1
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South Korea
Prior art keywords
relative humidity
soft capsule
dryer
drying
temperature
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Korean (ko)
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KR20190084990A (ko
Inventor
노튼 리처드 하트
레스터 데비드 풀퍼
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알.피.쉐러 테크놀러지즈 엘엘씨
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    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/06—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/10—Temperature; Pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/077—Manufacturing capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B11/00—Machines or apparatus for drying solid materials or objects with movement which is non-progressive
    • F26B11/02—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles
    • F26B11/04—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles rotating about a horizontal or slightly-inclined axis
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/004—Nozzle assemblies; Air knives; Air distributors; Blow boxes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/02—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure
    • F26B21/04—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure partly outside the drying enclosure
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/06—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/08—Humidity
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
    • F26B21/06—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/12—Velocity of flow; Quantity of flow, e.g. by varying fan speed, by modifying cross flow area
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/06—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour flowing through the materials or objects to be dried
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S53/00—Package making
    • Y10S53/90—Capsules

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Drying Of Solid Materials (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Disintegrating Or Milling (AREA)
KR1020197014547A 2016-12-08 2017-12-08 제어된 환경에서의 연질 캡슐의 가속 건조 Active KR102475555B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662431569P 2016-12-08 2016-12-08
US62/431,569 2016-12-08
PCT/US2017/065290 WO2018107019A1 (en) 2016-12-08 2017-12-08 Accelerated drying of soft capsules in a controlled environment

Publications (2)

Publication Number Publication Date
KR20190084990A KR20190084990A (ko) 2019-07-17
KR102475555B1 true KR102475555B1 (ko) 2022-12-07

Family

ID=62491357

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020197014547A Active KR102475555B1 (ko) 2016-12-08 2017-12-08 제어된 환경에서의 연질 캡슐의 가속 건조
KR1020197015395A Active KR102328603B1 (ko) 2016-12-08 2017-12-08 파손 가능성을 감소시키기 위해 캡슐 쉘 내의 응력을 완화시키는 방법

Family Applications After (1)

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KR1020197015395A Active KR102328603B1 (ko) 2016-12-08 2017-12-08 파손 가능성을 감소시키기 위해 캡슐 쉘 내의 응력을 완화시키는 방법

Country Status (14)

Country Link
US (3) US11026865B2 (enExample)
EP (2) EP3551158B1 (enExample)
JP (2) JP7129977B2 (enExample)
KR (2) KR102475555B1 (enExample)
CN (2) CN109923360B (enExample)
AU (2) AU2017374037B2 (enExample)
BR (1) BR112019010069A2 (enExample)
CA (2) CA3045127A1 (enExample)
CO (2) CO2019005095A2 (enExample)
ES (1) ES2927068T3 (enExample)
IL (2) IL266694B2 (enExample)
MX (2) MX2019005930A (enExample)
RU (2) RU2765074C2 (enExample)
WO (2) WO2018107019A1 (enExample)

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* Cited by examiner, † Cited by third party
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WO2018107019A1 (en) 2016-12-08 2018-06-14 R.P. Scherer Technologies, Llc Accelerated drying of soft capsules in a controlled environment
US20220249368A1 (en) * 2019-08-30 2022-08-11 Procaps S.A. Heat resistant chewable oral form with an agar matrix and manufacturing process thereof
US20210154099A1 (en) * 2019-11-22 2021-05-27 Karl Wei Cao Top liquid fill method and apparatus for hard capsules
CN114787512B (zh) * 2019-12-11 2024-07-05 W.L.戈尔及同仁股份有限公司 用于评估蒸气泵性能的方法
CN115792141B (zh) * 2023-01-06 2023-05-02 广州兰泰仪器有限公司 一种提高水活度仪平衡检测效率的方法及系统

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JP7129977B2 (ja) 2022-09-02
RU2019112049A (ru) 2021-01-12
MX2019005930A (es) 2019-07-08
CO2019005238A2 (es) 2019-05-31
IL266694A (en) 2019-07-31
IL266694B (en) 2022-11-01
US12161605B2 (en) 2024-12-10
EP3551158B1 (en) 2024-07-10
AU2017371180B2 (en) 2023-05-11
NZ752946A (en) 2025-03-28
AU2017371180A1 (en) 2019-05-23
BR112019010644A2 (pt) 2019-10-01
US20200069524A1 (en) 2020-03-05
KR102328603B1 (ko) 2021-11-18
CN109923360B (zh) 2022-02-11
CN110167510B (zh) 2021-12-14
IL266695A (en) 2019-07-31
ES2927068T3 (es) 2022-11-02
EP3551158A1 (en) 2019-10-16
US11026865B2 (en) 2021-06-08
IL266695B (en) 2022-09-01
EP3551950A1 (en) 2019-10-16
US20200069525A1 (en) 2020-03-05
KR20190084990A (ko) 2019-07-17
WO2018107080A1 (en) 2018-06-14
IL266694B2 (en) 2023-03-01
CN110167510A (zh) 2019-08-23
RU2765074C2 (ru) 2022-01-25
JP7013465B2 (ja) 2022-01-31
WO2018107019A1 (en) 2018-06-14
MX2019005956A (es) 2019-07-10
US20250025377A1 (en) 2025-01-23
EP3551158A4 (en) 2020-06-03
EP3551950B1 (en) 2022-06-22
RU2019113369A3 (enExample) 2021-03-18
CA3045127A1 (en) 2018-06-14
JP2020500643A (ja) 2020-01-16
CO2019005095A2 (es) 2019-05-31
CA3041560A1 (en) 2018-06-14
CN109923360A (zh) 2019-06-21
RU2019112049A3 (enExample) 2021-01-21
BR112019010069A2 (pt) 2019-08-20
RU2745334C2 (ru) 2021-03-24
RU2745334C9 (ru) 2021-05-24
AU2017374037B2 (en) 2023-02-23
AU2017374037A1 (en) 2019-05-16
JP2020501101A (ja) 2020-01-16
RU2019113369A (ru) 2021-01-13
EP3551158C0 (en) 2024-07-10
EP3551950A4 (en) 2020-06-03
KR20190069576A (ko) 2019-06-19

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