CA3045127A1 - A method to relieve stress in capsule shells to reduce propensity to break - Google Patents

A method to relieve stress in capsule shells to reduce propensity to break Download PDF

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Publication number
CA3045127A1
CA3045127A1 CA3045127A CA3045127A CA3045127A1 CA 3045127 A1 CA3045127 A1 CA 3045127A1 CA 3045127 A CA3045127 A CA 3045127A CA 3045127 A CA3045127 A CA 3045127A CA 3045127 A1 CA3045127 A1 CA 3045127A1
Authority
CA
Canada
Prior art keywords
capsule shell
capsule
shell
capsules
hard
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3045127A
Other languages
English (en)
French (fr)
Inventor
Lester David Fulper
Norton HART
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RP Scherer Technologies LLC
Original Assignee
RP Scherer Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RP Scherer Technologies LLC filed Critical RP Scherer Technologies LLC
Publication of CA3045127A1 publication Critical patent/CA3045127A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/077—Manufacturing capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B11/00—Machines or apparatus for drying solid materials or objects with movement which is non-progressive
    • F26B11/02—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles
    • F26B11/04—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in moving drums or other mainly-closed receptacles rotating about a horizontal or slightly-inclined axis
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements for supplying or controlling air or other gases for drying solid materials or objects
    • F26B21/20—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure
    • F26B21/25—Circulating air or gases in closed cycles, e.g. wholly within the drying enclosure partly outside the drying enclosure
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements for supplying or controlling air or other gases for drying solid materials or objects
    • F26B21/30—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/33—Humidity
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements for supplying or controlling air or other gases for drying solid materials or objects
    • F26B21/30—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/35—Temperature; Pressure
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements for supplying or controlling air or other gases for drying solid materials or objects
    • F26B21/30—Controlling, e.g. regulating, parameters of gas supply
    • F26B21/37—Velocity of flow; Quantity of flow
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00—Arrangements for supplying or controlling air or other gases for drying solid materials or objects
    • F26B21/50—Ducting arrangements from the source of air or other gases to the materials or objects being dried
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/06—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour flowing through the materials or objects to be dried
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S53/00—Package making
    • Y10S53/90—Capsules

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Manufacturing & Machinery (AREA)
  • Drying Of Solid Materials (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Disintegrating Or Milling (AREA)
CA3045127A 2016-12-08 2017-12-08 A method to relieve stress in capsule shells to reduce propensity to break Pending CA3045127A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662431569P 2016-12-08 2016-12-08
US62/431,569 2016-12-08
PCT/US2017/065398 WO2018107080A1 (en) 2016-12-08 2017-12-08 A method to relieve stress in capsule shells to reduce propensity to break

Publications (1)

Publication Number Publication Date
CA3045127A1 true CA3045127A1 (en) 2018-06-14

Family

ID=62491357

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3045127A Pending CA3045127A1 (en) 2016-12-08 2017-12-08 A method to relieve stress in capsule shells to reduce propensity to break

Country Status (14)

Country Link
US (3) US11026865B2 (enExample)
EP (2) EP3551950B1 (enExample)
JP (2) JP7129977B2 (enExample)
KR (2) KR102328603B1 (enExample)
CN (2) CN109923360B (enExample)
AU (2) AU2017371180B2 (enExample)
BR (1) BR112019010069A2 (enExample)
CA (1) CA3045127A1 (enExample)
CO (2) CO2019005095A2 (enExample)
ES (1) ES2927068T3 (enExample)
IL (2) IL266694B2 (enExample)
MX (2) MX2019005956A (enExample)
RU (2) RU2765074C2 (enExample)
WO (2) WO2018107019A1 (enExample)

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* Cited by examiner, † Cited by third party
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JP7129977B2 (ja) 2016-12-08 2022-09-02 アール．ピー．シェーラー テクノロジーズ、エルエルシー カプセルシェル応力を軽減してひび割れや損傷の可能性を減少させる方法
KR20220053623A (ko) * 2019-08-30 2022-04-29 프로갑스 에스.에이. 한천 매트릭스를 갖는 내열 저작성 경구 제형 및 이의 제조 방법
US20210154099A1 (en) * 2019-11-22 2021-05-27 Karl Wei Cao Top liquid fill method and apparatus for hard capsules
JP7314416B2 (ja) * 2019-12-11 2023-07-25 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 蒸気ポンプの性能を評価するための方法
CN115792141B (zh) * 2023-01-06 2023-05-02 广州兰泰仪器有限公司 一种提高水活度仪平衡检测效率的方法及系统

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Also Published As

Publication number Publication date
CN110167510B (zh) 2021-12-14
MX2019005930A (es) 2019-07-08
RU2745334C9 (ru) 2021-05-24
RU2019112049A (ru) 2021-01-12
WO2018107080A1 (en) 2018-06-14
WO2018107019A1 (en) 2018-06-14
KR20190084990A (ko) 2019-07-17
CN110167510A (zh) 2019-08-23
AU2017371180B2 (en) 2023-05-11
CN109923360B (zh) 2022-02-11
BR112019010069A2 (pt) 2019-08-20
EP3551950A4 (en) 2020-06-03
US20200069525A1 (en) 2020-03-05
EP3551158A4 (en) 2020-06-03
JP7129977B2 (ja) 2022-09-02
CO2019005238A2 (es) 2019-05-31
RU2745334C2 (ru) 2021-03-24
BR112019010644A2 (pt) 2019-10-01
EP3551158C0 (en) 2024-07-10
KR102328603B1 (ko) 2021-11-18
RU2019113369A (ru) 2021-01-13
IL266694B2 (en) 2023-03-01
CN109923360A (zh) 2019-06-21
IL266694B (en) 2022-11-01
RU2019113369A3 (enExample) 2021-03-18
NZ752946A (en) 2025-03-28
JP2020500643A (ja) 2020-01-16
US20250025377A1 (en) 2025-01-23
RU2019112049A3 (enExample) 2021-01-21
AU2017374037B2 (en) 2023-02-23
US11026865B2 (en) 2021-06-08
JP2020501101A (ja) 2020-01-16
MX2019005956A (es) 2019-07-10
IL266694A (en) 2019-07-31
KR102475555B1 (ko) 2022-12-07
AU2017374037A1 (en) 2019-05-16
ES2927068T3 (es) 2022-11-02
CO2019005095A2 (es) 2019-05-31
IL266695B (en) 2022-09-01
US20200069524A1 (en) 2020-03-05
KR20190069576A (ko) 2019-06-19
IL266695A (en) 2019-07-31
EP3551950B1 (en) 2022-06-22
EP3551158A1 (en) 2019-10-16
CA3041560A1 (en) 2018-06-14
US12161605B2 (en) 2024-12-10
EP3551950A1 (en) 2019-10-16
AU2017371180A1 (en) 2019-05-23
EP3551158B1 (en) 2024-07-10
JP7013465B2 (ja) 2022-01-31
RU2765074C2 (ru) 2022-01-25

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