RU2657955C2 - Контейнер под давлением, содержащий гемостатическую пасту - Google Patents

Контейнер под давлением, содержащий гемостатическую пасту Download PDF

Info

Publication number
RU2657955C2
RU2657955C2 RU2014140147A RU2014140147A RU2657955C2 RU 2657955 C2 RU2657955 C2 RU 2657955C2 RU 2014140147 A RU2014140147 A RU 2014140147A RU 2014140147 A RU2014140147 A RU 2014140147A RU 2657955 C2 RU2657955 C2 RU 2657955C2
Authority
RU
Russia
Prior art keywords
propellant
compartment
container
paste
valve
Prior art date
Application number
RU2014140147A
Other languages
English (en)
Russian (ru)
Other versions
RU2014140147A (ru
Inventor
Метте Крог ЙЕНСЕН
Кристиан ЛАРСЕН
Original Assignee
Ферросан Медикал Дивайсиз А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ферросан Медикал Дивайсиз А/С filed Critical Ферросан Медикал Дивайсиз А/С
Publication of RU2014140147A publication Critical patent/RU2014140147A/ru
Application granted granted Critical
Publication of RU2657955C2 publication Critical patent/RU2657955C2/ru

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/00491Surgical glue applicators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12181Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
    • A61B17/12186Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices liquid materials adapted to be injected
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14526Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/155Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02Sterilising, e.g. of complete packages
    • B65B55/04Sterilising wrappers or receptacles prior to, or during, packaging
    • B65B55/08Sterilising wrappers or receptacles prior to, or during, packaging by irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00535Surgical instruments, devices or methods pneumatically or hydraulically operated
    • A61B2017/00544Surgical instruments, devices or methods pneumatically or hydraulically operated pneumatically
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14513Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Reproductive Health (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Toxicology (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
RU2014140147A 2012-03-06 2013-03-05 Контейнер под давлением, содержащий гемостатическую пасту RU2657955C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201270099 2012-03-06
DKPA201270099 2012-03-06
PCT/DK2013/050054 WO2013131520A2 (en) 2012-03-06 2013-03-05 Pressurized container containing haemostatic paste

Publications (2)

Publication Number Publication Date
RU2014140147A RU2014140147A (ru) 2016-04-27
RU2657955C2 true RU2657955C2 (ru) 2018-06-18

Family

ID=48013685

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014140147A RU2657955C2 (ru) 2012-03-06 2013-03-05 Контейнер под давлением, содержащий гемостатическую пасту

Country Status (8)

Country Link
US (1) US11109849B2 (en:Method)
EP (1) EP2822474B1 (en:Method)
JP (1) JP6241624B2 (en:Method)
CN (1) CN104159527B (en:Method)
CA (1) CA2865349C (en:Method)
IN (1) IN2014DN08122A (en:Method)
RU (1) RU2657955C2 (en:Method)
WO (1) WO2013131520A2 (en:Method)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102014973A (zh) 2008-02-29 2011-04-13 弗罗桑医疗设备公司 用于促进止血和/或伤口愈合的装置
BR112014030962A2 (pt) 2012-06-12 2017-06-27 Ferrosan Medical Devices As métodos para preparação e para reconstituição de uma composição seca adequada para uso em hemostase e cicatrização de feridas, e, kit hemostático
JP6390873B2 (ja) 2013-06-21 2018-09-19 フェッローサン メディカル ディバイス エー/エス 減圧膨張させた乾燥組成物およびそれを保持するためのシリンジ
WO2015086028A1 (en) 2013-12-11 2015-06-18 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
WO2016058612A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
WO2016102446A1 (en) 2014-12-24 2016-06-30 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
RU2717356C2 (ru) 2015-07-03 2020-03-23 Ферросан Медикал Дивайсиз А/С Шприц для удерживания вакуума в состоянии хранения
GB2571080A (en) * 2018-02-14 2019-08-21 Medtrade Products Ltd Haemostatic material
ES2968412T3 (es) 2018-05-09 2024-05-09 Ferrosan Medical Devices As Método para preparar una composición hemostática
WO2020178419A1 (en) * 2019-03-06 2020-09-10 Gambro Lundia Ab Device and method for the delivery of a thrombin activated fibrin sealant
CN110946633A (zh) * 2019-11-26 2020-04-03 杭州电子科技大学 一种便携式快速挤出装置
WO2023056588A1 (en) * 2021-10-08 2023-04-13 Guangzhou Bioseal Biotech Co., Ltd. Systems, devices and methods of using hydraulic forces for delivering flowable, therapeutic compositions to surgical sites
CN120091796A (zh) * 2022-09-30 2025-06-03 弗罗桑医疗设备公司 用于止血的喷雾式贴片敷贴器、喷嘴组件以及将外科止血剂施用于目标部位的方法

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983001244A1 (en) * 1981-10-06 1983-04-14 Frutin, Bernard, Derek Pressurized dispensing apparatus
US4887743A (en) * 1987-06-10 1989-12-19 Blake William S Aerosol valve
RU2244519C2 (ru) * 1999-06-16 2005-01-20 Л.И.К.А. С.Р.Л. Устройство для осуществления микроабразивной обработки ткани человека и способ работы устройства для осуществления микроабразивной обработки ткани человека
US6861046B1 (en) * 1993-08-18 2005-03-01 Dow Corning France Device for dispensing a therapeutic or cosmetic substance onto the skin and a method of skin treatment
WO2009109194A2 (en) * 2008-02-29 2009-09-11 Ferrosan A/S Device for promotion of hemostasis and/or wound healing
US20100256671A1 (en) * 2009-04-07 2010-10-07 Biomedica Management Corporation Tissue sealant for use in noncompressible hemorrhage
WO2011047753A1 (en) * 2009-10-19 2011-04-28 Ferrosan Medical Devices A/S Malleable tip for agent applicator to a target site
EP2040724B1 (en) * 2006-05-18 2011-10-05 Biobalance Llc Biotherapeutic compositions comprising probiotic escherichia coli and metronidazole and uses thereof

Family Cites Families (504)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2899362A (en) 1959-08-11 Hemostatic sponges and method of
US2465357A (en) 1944-08-14 1949-03-29 Upjohn Co Therapeutic sponge and method of making
US2465860A (en) 1945-10-13 1949-03-29 Standard Manifold Company Inc Carbon holder
GB648619A (en) 1947-03-19 1951-01-10 Ferrosan As Process of producing sponges of gelatine and the like proteins
US2507244A (en) 1947-04-14 1950-05-09 Upjohn Co Surgical gelatin dusting powder and process for preparing same
CH264752A (de) 1947-06-03 1949-10-31 Hoffmann La Roche Verfahren zur Herstellung von Trägern für Arzneimittel.
GB697603A (en) 1948-10-06 1953-09-23 Sydney Arthur Gladstone Improvements in or relating to method of and devices for obtaining tissue from a tumour carried by a patient
US3089815A (en) 1951-10-11 1963-05-14 Lieb Hans Injectable pharmaceutical preparation, and a method of making same
US3224434A (en) 1962-11-06 1965-12-21 Waldemar Medical Res Foundatio Cell collector
GB1037937A (en) 1963-06-26 1966-08-03 Colgate Palmolive Co Pressurized dispensing containers
US3405712A (en) 1966-02-07 1968-10-15 Richard L. Pierick Desiccative syringe
US3869539A (en) 1966-12-01 1975-03-04 Ferrosan As Preparations containing fat-soluble vitamins in dry, particulate, free-flowing form dispersible in cold water and method of producing such preparations
US3514518A (en) 1967-12-19 1970-05-26 Pierre Charier Vadrot Process for preparation of gelatinous material from animal collagen
US3470109A (en) 1968-01-31 1969-09-30 Aloe Creme Lab Inc Method of making reconstitutable aloe gel in crystalline form
US3608593A (en) 1970-02-27 1971-09-28 Lilly Co Eli Method of filling powders into containers
US3678933A (en) 1970-07-17 1972-07-25 Moore Perk Corp Surgical sponge or bandage
US3892876A (en) 1971-11-30 1975-07-01 Leiner & Sons Wales Limited P Process of preparing freeze-dried gelatin
FR2167197B1 (fr) 1972-01-10 1974-06-21 Pont Brule Sa Compositions ameliorees contenant de la gelatine
US3815580A (en) 1972-08-31 1974-06-11 C Oster Apparatus for and method of collecting and preserving cytologic samples
US3946732A (en) 1973-08-08 1976-03-30 Ampoules, Inc. Two-chamber mixing syringe
SE420565B (sv) 1974-06-06 1981-10-19 Pharmacia Ab Hjelpmedel for intravaskuler administraring for anvendning i samband med intravaskuler administrering av en losning eller en suspension av ett diagnostiseringsmedel
US4002173A (en) 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US4013078A (en) 1974-11-25 1977-03-22 Feild James Rodney Intervertebral protector means
JPS5823410B2 (ja) 1974-11-12 1983-05-14 株式会社クラレ ヒドロゲルヨウキザイ
US4006220A (en) 1975-06-04 1977-02-01 Gottlieb Sheldon K Compositions and methods useful for repairing depressed cutaneous scars
US4280954A (en) 1975-07-15 1981-07-28 Massachusetts Institute Of Technology Crosslinked collagen-mucopolysaccharide composite materials
US4160022A (en) 1975-09-15 1979-07-03 Colgate Palmolive Company Toothpaste
US4098728A (en) 1976-01-02 1978-07-04 Solomon Rosenblatt Medical surgical sponge and method of making same
JPS5329936A (en) 1976-08-31 1978-03-20 Takeda Chem Ind Ltd Antibiotic composition
SE430609B (sv) 1976-12-21 1983-11-28 Sca Development Ab Sett att ur cellulosaderivat framstella absorberande material
DE2816130A1 (de) 1977-06-10 1978-12-21 Ato Chimie Verfahren und vorrichtung zur messung des haftvermoegens eines haftklebers
US4164559A (en) 1977-09-21 1979-08-14 Cornell Research Foundation, Inc. Collagen drug delivery device
US4208439A (en) 1977-10-25 1980-06-17 Societe D'assistance Technique Pour Produits Nestle S.A. Preparation of pasta
GB1584080A (en) 1977-12-05 1981-02-04 Ethicon Inc Absorbable hemostatic composition
DE2843963A1 (de) 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
US4265233A (en) 1978-04-12 1981-05-05 Unitika Ltd. Material for wound healing
US4179400A (en) 1978-05-09 1979-12-18 W. R. Grace & Co. Process for preparing catalytic solutions of sulfonium salts
AT359652B (de) 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
AT359653B (de) 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
DE3036033A1 (de) 1980-09-24 1982-05-06 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Wundbehandlungsmittel in pulverform und verfahren zu seiner herstellung
US4300494A (en) 1979-09-26 1981-11-17 Shell Oil Company Thermal insulated intake ports
DE2943520C2 (de) 1979-10-27 1982-05-19 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von Kollagenschwamm für medizinische oder kosmetische Zwecke
US4292972A (en) 1980-07-09 1981-10-06 E. R. Squibb & Sons, Inc. Lyophilized hydrocolloio foam
DE3105624A1 (de) 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
DE3267499D1 (en) 1981-03-18 1986-01-02 Fujirebio Kk Support material for use in serological testing and process for the production thereof
DE3146841A1 (de) 1981-11-26 1983-06-01 Beiersdorf Ag, 2000 Hamburg "neue wundbehandlungsmittel"
US4424208A (en) 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
DE3360633D1 (en) 1982-02-12 1985-10-03 Unitika Ltd Anti-cancer device
US4482386A (en) 1982-03-26 1984-11-13 Warner-Lambert Company Method of conditioning a water swellable hydrocolloid
US4543332A (en) 1982-03-29 1985-09-24 Miles Laboratories, Inc. Method for the preparation of spherical microorganism cell aggregates
JPS5928472A (ja) 1982-08-09 1984-02-15 Koken:Kk 細胞培養用基質およびこの基質を用いた細胞培養・分離法
US4540410A (en) 1982-11-16 1985-09-10 Serono Pharmaceutical Partners Lyophilized compositions, preparation and use thereof
JPS59113889A (ja) 1982-12-17 1984-06-30 Sumitomo Chem Co Ltd 固定化酵素もしくは固定化微生物菌体の製造方法
US4492305A (en) 1983-07-08 1985-01-08 Marion Laboratories, Inc. Package for collecting cultures
DE3466702D1 (en) 1983-07-14 1987-11-12 Hitachi Chemical Co Ltd Gelatin spherical gels and production thereof
JPS60100516A (ja) 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
JPS60110669A (ja) 1983-11-12 1985-06-17 株式会社林原生物化学研究所 圧出容器とその製造方法
US4515637A (en) 1983-11-16 1985-05-07 Seton Company Collagen-thrombin compositions
US4522302A (en) 1984-03-05 1985-06-11 Sterling Drug Inc. Pre-sterilized medical procedure kit packages
AT389815B (de) 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
US4600574A (en) 1984-03-21 1986-07-15 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Method of producing a tissue adhesive
US4837285A (en) 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
ZA851661B (en) 1984-03-29 1986-10-29 Minnesota Mining & Mfg Sorbent sheet material
JPS60214728A (ja) 1984-04-06 1985-10-28 Unitika Ltd 生理活性物質徐放性材料
SE456346B (sv) 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
JPS6144825A (ja) 1984-08-09 1986-03-04 Unitika Ltd 止血剤
GB8422950D0 (en) 1984-09-11 1984-10-17 Warne K J Hydrogel
JPS61122222A (ja) 1984-11-19 1986-06-10 Koken:Kk コラ−ゲン又はゼラチンとプロタミンとよりなる止血剤
US5165938A (en) 1984-11-29 1992-11-24 Regents Of The University Of Minnesota Wound healing agents derived from platelets
US5178883A (en) 1984-11-29 1993-01-12 Regents Of The University Of Minnesota Method for promoting hair growth
US4600533A (en) 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
JPS61209590A (ja) 1985-03-13 1986-09-17 Asama Kasei Kk 新規な固定化細胞およびそれを利用する醗酵生産法
US4997753A (en) 1985-04-04 1991-03-05 Verax Corporation Weighted collagen microsponge for immobilizing bioactive material
US4861714A (en) 1985-04-04 1989-08-29 Verax Corporation Weighted collagen microsponge for immobilizing bioactive material
US4863856A (en) 1985-04-04 1989-09-05 Verax Corporation Weighted collagen microsponge for immobilizing bioactive materials
AT382783B (de) 1985-06-20 1987-04-10 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
US5112750A (en) 1985-06-25 1992-05-12 Asama Chemical Co., Ltd. Immobilized cells and culture method utilizing the same
US4851521A (en) 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
US5007916A (en) 1985-08-22 1991-04-16 Johnson & Johnson Medical, Inc. Method and material for prevention of surgical adhesions
JPS6270318A (ja) 1985-09-25 1987-03-31 Nippon Kayaku Co Ltd 止血及び創傷保護剤
US4696812A (en) 1985-10-28 1987-09-29 Warner-Lambert Company Thrombin preparations
US20020192271A1 (en) 1985-11-26 2002-12-19 Hedner Ulla Karin Elisabeth Method for causing local hemostasis and hemostatic composition for local hemostasis
US5180583A (en) 1985-11-26 1993-01-19 Hedner Ulla K E Method for the treatment of bleeding disorders
IE59361B1 (en) 1986-01-24 1994-02-09 Akzo Nv Pharmaceutical preparation for obtaining a highly viscous hydrogel or suspension
JPS62221357A (ja) 1986-03-20 1987-09-29 ジエクス株式会社 生物体表面への塗布剤
IL78826A (en) 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
US4946870A (en) 1986-06-06 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Delivery systems for pharmaceutical or therapeutic actives
US5300494A (en) 1986-06-06 1994-04-05 Union Carbide Chemicals & Plastics Technology Corporation Delivery systems for quaternary and related compounds
US4832686A (en) 1986-06-24 1989-05-23 Anderson Mark E Method for administering interleukin-2
US4803075A (en) 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
US4702737A (en) 1986-07-14 1987-10-27 Pizzino Joanne L Dual dose syringe
US4743229A (en) 1986-09-29 1988-05-10 Collagen Corporation Collagen/mineral mixing device and method
US4965203A (en) 1987-01-28 1990-10-23 Warner-Lambert Company Purified thrombin preparations
US4885161A (en) 1987-03-11 1989-12-05 Medi-Tech International Corporation Wound dressings in gelled paste form
CA1305069C (en) 1987-03-11 1992-07-14 John Cornell Wound dressings in sheet or gelled paste form
US5080893A (en) 1988-05-31 1992-01-14 University Of Florida Method for preventing surgical adhesions using a dilute solution of polymer
US5690954A (en) 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
US4752466A (en) 1987-08-31 1988-06-21 Johnson & Johnson Products, Inc. Thrombin aerosol
US5017229A (en) 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
JPS6485653A (en) 1987-09-28 1989-03-30 Terumo Corp Drug receiving container
JPH01130519A (ja) 1987-11-16 1989-05-23 Mitsubishi Electric Corp Mocvd結晶成長装置
DE68918155T2 (de) 1988-05-02 1995-03-02 Matrix Pharma Chirurgisches Klebstoffmaterial.
IT1219587B (it) 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US4936835A (en) 1988-05-26 1990-06-26 Haaga John R Medical needle with bioabsorbable tip
US5350573A (en) 1988-05-31 1994-09-27 University Of Florida Research Foundation, Inc. Method and composition for preventing surgical adhesions
US5140016A (en) 1988-05-31 1992-08-18 University Of Florida Method and composition for preventing surgical adhesions using a dilute solution of polymer
US5024841A (en) 1988-06-30 1991-06-18 Collagen Corporation Collagen wound healing matrices and process for their production
US5447966A (en) 1988-07-19 1995-09-05 United States Surgical Corporation Treating bioabsorbable surgical articles by coating with glycerine, polalkyleneoxide block copolymer and gelatin
US4920158A (en) 1989-10-11 1990-04-24 Medipro Sciences Limited Hydrogel-forming wound dressing or skin coating material
US5041292A (en) 1988-08-31 1991-08-20 Theratech, Inc. Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
US4925677A (en) 1988-08-31 1990-05-15 Theratech, Inc. Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
EP0365705A1 (de) 1988-10-26 1990-05-02 Zentralna Problemna Laboratoria Po Kryobiologia I Lyophilisazia Biopräparat zur Behandlung von Wunden
US5135751A (en) 1988-11-16 1992-08-04 Mediventures Incorporated Composition for reducing postsurgical adhesions
US5126141A (en) 1988-11-16 1992-06-30 Mediventures Incorporated Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides
US5614587A (en) 1988-11-21 1997-03-25 Collagen Corporation Collagen-based bioadhesive compositions
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US4891359A (en) 1988-12-08 1990-01-02 Johnson & Johnson Patient Care, Inc. Hemostatic collagen paste composition
DE3903672C1 (en:Method) 1989-02-08 1990-02-01 Lohmann Gmbh & Co Kg
US5062834A (en) 1989-02-24 1991-11-05 Product Development (S.G.Z.) Ltd Device for dispensing a liquid particularly useful for delivering medicaments at a predetermined rate
DK223389D0 (da) 1989-05-05 1989-05-05 Ferrosan As Saarsvamp
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
EP0493387B1 (en) 1989-08-10 1993-10-20 W.L. Gore & Associates, Inc. A medical dispensing system for tissue adhesive components
US5196185A (en) 1989-09-11 1993-03-23 Micro-Collagen Pharmaceutics, Ltd. Collagen-based wound dressing and method for applying same
FR2652573B1 (fr) 1989-10-03 1991-12-13 Atochem Procede de fabrication du 1,1,1-chlorodifluoroethane.
US5061274A (en) 1989-12-04 1991-10-29 Kensey Nash Corporation Plug device for sealing openings and method of use
US5350581A (en) 1989-12-14 1994-09-27 Pharmetrix Corporation Method for manufacturing transdermal devices
US5281528A (en) 1989-12-18 1994-01-25 Warner-Lambert Company Process for purified thromboplastin for ultra-pure thrombin preparation
US5219328A (en) 1990-01-03 1993-06-15 Cryolife, Inc. Fibrin sealant delivery method
US5134229A (en) 1990-01-12 1992-07-28 Johnson & Johnson Medical, Inc. Process for preparing a neutralized oxidized cellulose product and its method of use
US4982769A (en) 1990-02-21 1991-01-08 Survival Technology, Inc. Package
JPH0813750B2 (ja) 1990-03-01 1996-02-14 持田製薬株式会社 経口用トロンビン製剤
US5306501A (en) 1990-05-01 1994-04-26 Mediventures, Inc. Drug delivery by injection with thermoreversible gels containing polyoxyalkylene copolymers
US5595735A (en) 1990-05-23 1997-01-21 Johnson & Johnson Medical, Inc. Hemostatic thrombin paste composition
US5634943A (en) 1990-07-12 1997-06-03 University Of Miami Injectable polyethylene oxide gel implant and method for production
US5209776A (en) 1990-07-27 1993-05-11 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5292362A (en) 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5108421A (en) 1990-10-01 1992-04-28 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5192300A (en) 1990-10-01 1993-03-09 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
DE59005286D1 (de) 1990-10-04 1994-05-11 Kallies Import Export Vertrieb Stabilisiertes Thrombin, seine Herstellung und seine Verwendung als Thrombinzeitreagens.
NO302481B1 (no) 1990-10-16 1998-03-09 Takeda Chemical Industries Ltd Polymer for et preparat med forlenget frigjöring, samt preparat med forlenget frigjöring
US5129882A (en) 1990-12-27 1992-07-14 Novoste Corporation Wound clotting device and method of using same
US6391343B1 (en) 1991-01-15 2002-05-21 Hemosphere, Inc. Fibrinogen-coated particles for therapeutic use
JPH06505656A (ja) 1991-02-13 1994-06-30 フュージョン メデイカル テクノロジーズ インコーポレーテッド 組織溶接用充填剤材料
US5749895A (en) 1991-02-13 1998-05-12 Fusion Medical Technologies, Inc. Method for bonding or fusion of biological tissue and material
US5690675A (en) 1991-02-13 1997-11-25 Fusion Medical Technologies, Inc. Methods for sealing of staples and other fasteners in tissue
US5669934A (en) 1991-02-13 1997-09-23 Fusion Medical Technologies, Inc. Methods for joining tissue by applying radiofrequency energy to performed collagen films and sheets
CA2079444C (en) 1991-02-14 2004-02-03 Rimona Margalit Binding of recognizing substances to liposomes
US5605938A (en) 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
DE4119140C2 (de) 1991-06-11 1994-05-11 Merz & Co Gmbh & Co Poröser, in Körperflüssigkeiten und Sekreten löslicher, spongoider Formkörper, dessen Herstellung und Verwendung
CA2089487A1 (en) 1991-06-14 1992-12-15 Suk-Zu Song Collagen film drug delivery for proteins
NL9101051A (nl) 1991-06-18 1993-01-18 Ashridge Ag Sluitinrichting voor een bloedvat of dergelijke.
FR2679772B1 (fr) 1991-08-02 1995-05-19 Peters Sa Emboles en particules non resorbables enrobees de materiau hemostatique.
IT1251151B (it) 1991-08-05 1995-05-04 Fidia Spa Materiale spugnoso essenzialmente costituito da acido ialuronico,o suoi derivati
FI941627A7 (fi) 1991-10-09 1994-06-08 Lectec Corp Vesipitoinen geeli haavan peittämiseksi ja pakkaus sitä varten
US6620436B1 (en) 1991-10-09 2003-09-16 Lectec Corporation Mixing and dispensing package for a wound dressing
AU2793292A (en) 1991-10-11 1993-05-03 Novo Nordisk A/S Hemostatic composition for local hemostasis
AT398079B (de) 1991-11-04 1994-09-26 Immuno Ag Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung
ATE137962T1 (de) 1991-12-05 1996-06-15 Alfatec Pharma Gmbh Pharmazeutisch applizierbares nanosol und verfahren zu seiner herstellung
ATE193037T1 (de) 1992-02-28 2000-06-15 Collagen Corp Hochkonzentrierte homogenisierte kollagenzusammensetzungen
CA2128783C (en) 1992-02-28 2004-10-12 Donald G. Wallace Injectable ceramic compositions and methods for their preparation and use
US5204382A (en) 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
US5468505A (en) 1992-02-28 1995-11-21 Board Of Regents, The University Of Texas System Local delivery of fibrinolysis enhancing agents
US5384333A (en) 1992-03-17 1995-01-24 University Of Miami Biodegradable injectable drug delivery polymer
GB9206509D0 (en) 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
GB2266239B (en) 1992-03-25 1996-03-06 Jevco Ltd Wound healing compositions containing chondroitin sulphate oligosaccharides
WO1993021844A1 (en) 1992-04-23 1993-11-11 Scimed Life Systems, Inc. Apparatus and method for sealing vascular punctures
IL105529A0 (en) 1992-05-01 1993-08-18 Amgen Inc Collagen-containing sponges as drug delivery for proteins
JPH05308969A (ja) 1992-05-13 1993-11-22 Japan Vilene Co Ltd 酵素保持体及びその製造方法
AU4406793A (en) 1992-06-04 1993-12-30 Clover Consolidated, Limited Water-soluble polymeric carriers for drug delivery
US5547376A (en) 1992-06-18 1996-08-20 Harrel; Stephen K. Methods and apparatus for containing and recovering abrasive powders from an abrasive polisher
US5385606A (en) 1992-07-06 1995-01-31 Kowanko; Nicholas Adhesive composition and method
US5413571A (en) 1992-07-16 1995-05-09 Sherwood Medical Company Device for sealing hemostatic incisions
US5443481A (en) 1992-07-27 1995-08-22 Lee; Benjamin I. Methods and device for percutaneous sealing of arterial puncture sites
US5428022A (en) 1992-07-29 1995-06-27 Collagen Corporation Composition of low type III content human placental collagen
US5514379A (en) 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
DE4227681C2 (de) 1992-08-21 1995-05-18 Becker & Co Naturinwerk Wundabdeckungsmaterial auf der Basis von Kollagenfasern und Verfahren zu seiner Herstellung
AU4926193A (en) 1992-09-21 1994-04-12 Vitaphore Corporation Embolization plugs for blood vessels
WO1994008552A2 (en) 1992-10-19 1994-04-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
ATE206602T1 (de) 1992-11-12 2001-10-15 Neville Alleyne Einrichtung zum schutz des herzens
US5334216A (en) 1992-12-10 1994-08-02 Howmedica Inc. Hemostatic plug
US5667839A (en) 1993-01-28 1997-09-16 Collagen Corporation Human recombinant collagen in the milk of transgenic animals
IT1263144B (it) 1993-02-04 1996-08-01 Lanfranco Callegaro Composizioni farmaceutiche comprendenti materiale spugnoso costituito da derivati esterei dell'acido ialuronico in associazione con altre sostanze farmacologicamente attive
JPH08131B2 (ja) 1993-03-05 1996-01-10 新田ゼラチン株式会社 止血用パッド
CA2159626C (en) 1993-04-02 2001-10-02 Lingna Li Method for delivering beneficial compositions to hair follicles
WO1994023788A1 (en) 1993-04-20 1994-10-27 Medchem Products, Inc. Apparatus and method for applying a particulate hemostatic agent to living tissue
US5723308A (en) 1993-05-14 1998-03-03 Minnesota Mining And Manufacturing Company Culture medium for rapid count of coliform bacteria
GB9310085D0 (en) * 1993-05-17 1993-06-30 Reynolds David L Syringe
US5951583A (en) 1993-05-25 1999-09-14 Vascular Solutions, Inc. Thrombin and collagen procoagulant and process for making the same
JP3639593B2 (ja) 1993-05-31 2005-04-20 科研製薬株式会社 塩基性線維芽細胞増殖因子含有架橋ゼラチンゲル製剤
US5387208A (en) 1993-07-26 1995-02-07 The Procter & Gamble Co. Absorbent core having improved dry/wet integrity
US5798091A (en) 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
US5394886A (en) 1993-09-20 1995-03-07 Nabai; Hossein Skin biopsy plug and method
JPH0790241A (ja) 1993-09-22 1995-04-04 Menicon Co Ltd 眼用レンズ材料用仮接着剤
DE69433939T2 (de) 1993-11-03 2005-08-11 Clarion Pharmaceuticals, Inc., Madison Hämostatisches pflaster
DE69430054T2 (de) 1993-12-30 2002-10-24 Nitta Gelatin Inc., Osaka Verfahren zum einbetten von tierkulturzellen
FR2715309B1 (fr) 1994-01-24 1996-08-02 Imedex Composition adhésive, à usage chirurgical, à base de collagène modifié par coupure oxydative et non réticulé.
US5441491A (en) 1994-02-04 1995-08-15 Verschoor; Jacob Method and composition for treating biopsy wounds
DE4407875C2 (de) 1994-03-04 1996-04-04 Ankerpharm Gmbh Ankerwerk Rudo Medizinischer Schwamm aus biologisch resorbierbaren Materialien, Verfahren und Vorrichtung zu dessen Herstellung
AU695266B2 (en) 1994-03-18 1998-08-13 Baxter International Inc. Topical fibrinogen complex
ITPD940054A1 (it) 1994-03-23 1995-09-23 Fidia Advanced Biopolymers Srl Polisaccaridi solfatati
US5674275A (en) 1994-04-06 1997-10-07 Graphic Controls Corporation Polyacrylate and polymethacrylate ester based hydrogel adhesives
US5531759A (en) 1994-04-29 1996-07-02 Kensey Nash Corporation System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating
CA2146090C (en) 1994-05-10 1998-11-24 Mark E. Mitchell Apparatus and method of mixing materials in a sterile environment
JP3107726B2 (ja) 1994-05-13 2000-11-13 株式会社クラレ 水膨潤性高分子ゲル
EP0712635B1 (en) 1994-05-13 2003-05-02 Kuraray Co., Ltd. Medical polymer gel
ATE168554T1 (de) 1994-05-23 1998-08-15 Liposome Co Inc Vorrichtung zur herstellung einer formulierung
US5462860A (en) 1994-06-06 1995-10-31 Minnesota Mining And Manufacturing Company Conditioned culture medium for rapid growth and detection of microbes
GB9415739D0 (en) 1994-07-30 1994-09-21 Scimat Ltd Gel wound dressing
US5599735A (en) 1994-08-01 1997-02-04 Texas Instruments Incorporated Method for doped shallow junction formation using direct gas-phase doping
US5516532A (en) 1994-08-05 1996-05-14 Children's Medical Center Corporation Injectable non-immunogenic cartilage and bone preparation
US5588745A (en) 1994-09-02 1996-12-31 Howmedica Methods and apparatus for mixing bone cement components using an evacuated mixing chamber
US5931165A (en) 1994-09-06 1999-08-03 Fusion Medical Technologies, Inc. Films having improved characteristics and methods for their preparation and use
JP2858087B2 (ja) 1994-09-19 1999-02-17 グンゼ株式会社 組織培養用基材及び組織培養法
WO1996010374A1 (en) 1994-10-03 1996-04-11 Otogen Corporation Differentially biodegradable biomedical implants
FR2726571B1 (fr) 1994-11-03 1997-08-08 Izoret Georges Colle biologique, procede de preparation et dispositif d'application pour colle biologique, et durcisseurs pour colle biologique
US5660854A (en) 1994-11-28 1997-08-26 Haynes; Duncan H Drug releasing surgical implant or dressing material
WO1996022115A1 (en) 1995-01-16 1996-07-25 Baxter International Inc. Self-supporting sheet-like material of cross-linked fibrin for preventing post operative adhesions
US20030039695A1 (en) 2001-08-10 2003-02-27 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Collagen carrier of therapeutic genetic material, and method
US6146587A (en) * 1995-03-06 2000-11-14 Morgan; David M. Sanitizing dry spray material and applicator
US5698213A (en) 1995-03-06 1997-12-16 Ethicon, Inc. Hydrogels of absorbable polyoxaesters
US5580923A (en) 1995-03-14 1996-12-03 Collagen Corporation Anti-adhesion films and compositions for medical use
US5876372A (en) 1995-03-22 1999-03-02 Abbott Laboratories Syringe system accomodating seperate prefilled barrels for two constituents
DE19513666C1 (de) 1995-04-11 1996-11-28 Behringwerke Ag Vorrichtung zum Zusammenführen einer ersten flüssigen und einer zweiten festen oder flüssigen Komponente mittels Unterdruck unter sterilen Bedingungen
JP3799626B2 (ja) 1995-04-25 2006-07-19 有限会社ナイセム 心臓血管修復材及びその製造方法
US5677284A (en) 1995-06-06 1997-10-14 Regen Biologics, Inc. Charged collagen particle-based delivery matrix
AU5638096A (en) 1995-06-07 1996-12-30 Clarion Pharmaceuticals, Inc. Non-biological patch for hemostasis
US6129761A (en) 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
DE19521324C1 (de) 1995-06-12 1996-10-31 Immuno Ag Gewebeklebstoff und Verwendung desselben als Hämostyptikum
WO1997013461A1 (en) 1995-10-11 1997-04-17 Fusion Medical Technologies, Inc. Device and method for sealing tissue
AU7609896A (en) 1995-11-07 1997-05-29 Fusion Medical Technologies, Inc. Methods and articles for fusing polysaccharide-containing matrix layers to tissue
WO1997017025A1 (en) 1995-11-07 1997-05-15 Fusion Medical Technologies, Inc. Methods and articles for fusing matrix layers containing non-collagenous proteins to tissue
AU7723396A (en) 1995-11-07 1997-05-29 Fusion Medical Technologies, Inc. Methods and articles for fusing matrix layers containing non-biologic polymers to tissue
US6464111B2 (en) 1995-11-13 2002-10-15 L'oreal Dispenser containing a product and dispensing method
ATE330644T1 (de) 1995-12-18 2006-07-15 Angiotech Biomaterials Corp Vernetzten polymerisatmassen und verfahren für ihre verwendung
US6458889B1 (en) 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US5752974A (en) 1995-12-18 1998-05-19 Collagen Corporation Injectable or implantable biomaterials for filling or blocking lumens and voids of the body
US5748318A (en) 1996-01-23 1998-05-05 Brown University Research Foundation Optical stress generator and detector
WO1997029792A1 (en) 1996-02-20 1997-08-21 Cohesion Corporation Tissue sealant compositions and methods of use thereof
US5782917A (en) 1996-02-26 1998-07-21 Sunmed, Inc. Intramedullary bone plug
SI0796623T1 (en) 1996-03-20 2005-10-31 Baxter Aktiengesellschaft Pharmaceutical preparation for the treatment of blood coagulation disorders
DE69724243T2 (de) 1996-04-04 2004-06-17 Baxter Ag Blutstillender schwamm auf kollagenbasis
US5948427A (en) 1996-04-25 1999-09-07 Point Medical Corporation Microparticulate surgical adhesive
WO1997041899A1 (en) 1996-05-03 1997-11-13 Innogenetics N.V. New medicaments containing gelatin cross-linked with oxidized polysaccharides
EP0914096B1 (en) 1996-05-17 2003-08-13 Elan Drug Delivery Limited Microparticles and their use in wound therapy
FR2749759B1 (fr) 1996-06-17 1999-11-26 Adir Utilisation de sels de strontium pour l'obtention de compositions pharmaceutiques destinees au traitement de l'arthrose
US5791352A (en) 1996-06-19 1998-08-11 Fusion Medical Technologies, Inc. Methods and compositions for inhibiting tissue adhesion
EP0917444A1 (en) 1996-07-12 1999-05-26 Baxter Travenol Laboratories, Inc. A fibrin delivery device and method for forming fibrin on a surface
US5902832A (en) 1996-08-20 1999-05-11 Menlo Care, Inc. Method of synthesizing swollen hydrogel for sphincter augmentation
US6063061A (en) 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6706690B2 (en) 1999-06-10 2004-03-16 Baxter Healthcare Corporation Hemoactive compositions and methods for their manufacture and use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US7871637B2 (en) 1996-08-27 2011-01-18 Baxter International Inc. Dry hemostatic compositions and methods for their preparation
US7320962B2 (en) 1996-08-27 2008-01-22 Baxter International Inc. Hemoactive compositions and methods for their manufacture and use
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
CA2211629A1 (en) 1996-09-17 1998-03-17 Bernard Sams Vial connector assembly for a medicament container
AU4648697A (en) 1996-09-23 1998-04-14 Chandrashekar Pathak Methods and devices for preparing protein concentrates
US5795330A (en) 1996-10-10 1998-08-18 Etex Corporation Mixing device
US7341598B2 (en) 1999-01-13 2008-03-11 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
JP2001508689A (ja) 1997-01-16 2001-07-03 コヘージョン コーポレイション 凍結乾燥コラーゲンベースの生体材料、それらの調製プロセスおよび使用
US6045570A (en) 1997-02-11 2000-04-04 Biointerventional Corporation Biological sealant mixture and system for use in percutaneous occlusion of puncture sites and tracts in the human body and method
US5782860A (en) 1997-02-11 1998-07-21 Biointerventional Corporation Closure device for percutaneous occlusion of puncture sites and tracts in the human body and method
US6193670B1 (en) * 1997-02-14 2001-02-27 Tricardia, Llc Hemostatic agent delivery device having built-in pressure sensor
US5905029A (en) 1997-02-19 1999-05-18 Fritz Berthold Method for rapid hygiene testing
ES2251073T3 (es) 1997-02-20 2006-04-16 Cook Incorporated Dispositivo medico implantable dotado de un revestimiento.
FR2759980A1 (fr) 1997-02-25 1998-08-28 Bras Michel Conditionnement de deux substances destinees a etre melangees
US5965377A (en) 1997-03-24 1999-10-12 Baystate Medical Center Method for determining the presence of mutated BRCA protein
US5939259A (en) 1997-04-09 1999-08-17 Schleicher & Schuell, Inc. Methods and devices for collecting and storing clinical samples for genetic analysis
US6117444A (en) 1997-04-10 2000-09-12 Brigham & Women's Hospital Polyethylene glycol/microfibrillar collagen composite serves as a resorbable hemostatic agent
US6716435B1 (en) 1997-04-18 2004-04-06 Ganeden Biotech, Inc. Absorbent product containing absorbent structure and Bacillus coagulans
US20020039594A1 (en) 1997-05-13 2002-04-04 Evan C. Unger Solid porous matrices and methods of making and using the same
EP0986408B1 (en) 1997-06-03 2005-05-11 Innogenetics N.V. New medicaments based on polymers composed of methacrylamide-modified gelatin
US5908054A (en) 1997-06-16 1999-06-01 Fusion Medical Technologies, Inc. Fluid dispersion and delivery assembly and method
US5957166A (en) 1997-06-16 1999-09-28 Fusion Medical Technologies, Inc. Method and apparatus for dispersing fluid into a material
JP2002514960A (ja) 1997-06-18 2002-05-21 コヘージョン テクノロジーズ,インコーポレイテッド トロンビンおよびミクロフィブリルコラーゲンを含む組成物、ならびにその調製および使用の方法
IT1294797B1 (it) 1997-07-28 1999-04-15 Fidia Advanced Biopolymers Srl Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante
US6042262A (en) 1997-07-29 2000-03-28 Stryker Technologies Corportion Apparatus for storing, mixing, and dispensing two-component bone cement
US6171276B1 (en) 1997-08-06 2001-01-09 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
ZA987019B (en) 1997-08-06 1999-06-04 Focal Inc Hemostatic tissue sealants
CA2301018C (en) 1997-08-22 2006-06-20 Denki Kagaku Kogyo Kabushiki Kaisha Hyaluronic acid gel, method of its production and medical material containing it
WO1999012032A1 (en) 1997-09-04 1999-03-11 Pharmacia & Upjohn Company A method for the evaluation of antiviral drugs
ES2251782T3 (es) 1997-09-16 2006-05-01 Integra Lifesciences Corporation Producto para promover el crecimiento del tejido dural o meningeo que comprende colageno.
US5997895A (en) 1997-09-16 1999-12-07 Integra Lifesciences Corporation Dural/meningeal repair product using collagen matrix
US6168788B1 (en) 1997-09-26 2001-01-02 Leon Wortham Fibrin glue without fibrinogen and biosealant compositions and methods
GB2329840C (en) 1997-10-03 2007-10-05 Johnson & Johnson Medical Biopolymer sponge tubes
DK1021357T3 (da) * 1997-10-07 2004-07-12 Rocep Lusol Holdings Sammensat stempel til brug i en dispenseringsindretning
US6303323B1 (en) 1997-10-21 2001-10-16 Cancer Research Campaign Technology Limited Detection of dysplastic or neoplastic cells using anti-MCM5 antibodies
JPH11155951A (ja) 1997-12-01 1999-06-15 Kaken Pharmaceut Co Ltd 減圧シリンジおよびその製造方法
GB9727102D0 (en) 1997-12-22 1998-02-25 Andaris Ltd Microparticles and their therapeutic use
JP3483753B2 (ja) 1997-12-29 2004-01-06 タキロン株式会社 生体内分解吸収性可塑性粘着物
US6099952A (en) 1998-02-18 2000-08-08 Xomed Surgical Products, Inc. Medical sponge having mucopolysaccharide coating
EP1059957B1 (en) 1998-03-06 2007-08-29 Baxter International Inc. Turbulence mixing head for a tissue sealant applicator and spray head for same
AUPP223498A0 (en) 1998-03-06 1998-04-02 Southcorp Australia Pty Ltd A container
EP1061931A2 (en) 1998-03-10 2000-12-27 Baxter International Inc. Thrombin preparation and products and fibrin sealant methods employing same
US6179872B1 (en) 1998-03-17 2001-01-30 Tissue Engineering Biopolymer matt for use in tissue repair and reconstruction
US20020025921A1 (en) 1999-07-26 2002-02-28 Petito George D. Composition and method for growing, protecting, and healing tissues and cells
DE69917618T2 (de) 1998-04-03 2005-06-23 Egalet A/S Zusammensetzung mit kontrollierter wirkstoff-freisetzung
US20020061842A1 (en) 1998-04-10 2002-05-23 Octapharma Ag Method for sterilizing a native collagen in liquid medium, sterile native collagen obtained, compositions containing it and uses
US6200328B1 (en) 1998-05-01 2001-03-13 Sub Q, Incorporated Device and method for facilitating hemostasis of a biopsy tract
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
EP1109498A4 (en) 1998-08-04 2003-01-08 Fusion Medical Technologies PERCUTANEOUS DEVICE AND METHOD FOR CLOSING A LEFT TRACE IN TISSUES
US6334865B1 (en) 1998-08-04 2002-01-01 Fusion Medical Technologies, Inc. Percutaneous tissue track closure assembly and method
US6613070B2 (en) 1998-08-04 2003-09-02 Baxter International Inc. System and method for sealing vascular penetrations with hemostatic gels
US6274090B1 (en) 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
MXPA01001510A (es) 1998-08-10 2003-08-20 Fibrogen Inc Composiciones hemostaticas de colageno tipo i y tipo iii para usarse como sellador vascular y vendaje para heridas.
US20020015724A1 (en) 1998-08-10 2002-02-07 Chunlin Yang Collagen type i and type iii hemostatic compositions for use as a vascular sealant and wound dressing
ATE444084T1 (de) 1998-11-12 2009-10-15 Internat Mfg Group Inc Hämostatische vernetzte dextranperlen verwendbar zur schnellen blutgerinnung und hämostase
US6110484A (en) 1998-11-24 2000-08-29 Cohesion Technologies, Inc. Collagen-polymer matrices with differential biodegradability
US6361551B1 (en) 1998-12-11 2002-03-26 C. R. Bard, Inc. Collagen hemostatic fibers
US6454787B1 (en) 1998-12-11 2002-09-24 C. R. Bard, Inc. Collagen hemostatic foam
US6328229B1 (en) 1998-12-18 2001-12-11 Cohesion Technologies, Inc. Low volume mixing spray head for mixing and dispensing of two reactive fluid components
WO2000038752A1 (de) 1998-12-23 2000-07-06 Aventis Behring Gmbh Fibrinklebergranulat und verfahren zu dessen herstellung
US6283933B1 (en) 1998-12-23 2001-09-04 Closure Medical Corporation Applicator for dispensable liquids
EP1022031B1 (en) 1999-01-21 2005-03-23 Nipro Corporation Suturable adhesion-preventing membrane
US6862470B2 (en) 1999-02-02 2005-03-01 Senorx, Inc. Cavity-filling biopsy site markers
AU773826B2 (en) 1999-02-19 2004-06-10 Denki Kagaku Kogyo Kabushiki Kaisha Hyaluronic acid gel composition, process for producing the same, and medical material containing the same
WO2000061201A1 (en) 1999-04-14 2000-10-19 Ganeden Biotech, Inc. Methods for inhibiting microbial infections associated with sanitary products
US6312725B1 (en) 1999-04-16 2001-11-06 Cohesion Technologies, Inc. Rapid gelling biocompatible polymer composition
EP1053758A1 (de) 1999-05-19 2000-11-22 Resorba Chirurgisches Nahtmaterial Franz Hiltner GmbH & Co. Bioabsorbierbares Implantat
US6544541B1 (en) 1999-06-02 2003-04-08 Cardiovascular Solutions, Inc. Devices and compounds for treating arterial restenosis
US6472162B1 (en) 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
US20020019062A1 (en) 1999-06-18 2002-02-14 Peter Lea Assay devices
CA2382670A1 (en) 1999-08-26 2001-03-01 Ganeden Biotech, Inc. Use of emu oil a carrier for antifungal, antibacterial, and antiviral medications
ATE434010T1 (de) 1999-08-27 2009-07-15 Angiodevice Internat Gmbh Interpenetrierende polymernetzwerke zur verwendung als hochfeste medizinische dichtungsmasse
US6312474B1 (en) 1999-09-15 2001-11-06 Bio-Vascular, Inc. Resorbable implant materials
US6221109B1 (en) 1999-09-15 2001-04-24 Ed. Geistlich Söhne AG fur Chemische Industrie Method of protecting spinal area
FR2799654B1 (fr) 1999-10-13 2002-01-11 Sod Conseils Rech Applic Dispositif pour reconstituer une solution, une suspension ou une dispersion therapeutique et procede de preparation et de conditionnement dans ce dispositif
ATE284230T1 (de) 1999-10-15 2004-12-15 Inst Genetics Llc Zusammensetzungen zur abgabe osteogener proteine
JP2001199903A (ja) 1999-11-09 2001-07-24 Eizo Mori 核酸含有複合体
WO2001047584A1 (en) 1999-12-28 2001-07-05 Asger Lau Dalmose Dual chamber syringe with a dual function piston
US20030095993A1 (en) 2000-01-28 2003-05-22 Hanne Bentz Gel-infused sponges for tissue repair and augmentation
AU2001234623A1 (en) 2000-01-28 2001-08-07 Orthogene, Inc. Gel-infused sponges for tissue repair and augmentation
IT1317832B1 (it) 2000-02-15 2003-07-15 Eurores S R L Procedimento per la preparazione di collagene micronizzato e sueapplicazioni terapeutiche.
JP2003535620A (ja) 2000-02-18 2003-12-02 リジェネレーション テクノロジーズ インク. 増殖因子および他の添加物を注入した移植用組織
US7220276B1 (en) 2000-03-06 2007-05-22 Surmodics, Inc. Endovascular graft coatings
WO2001075418A1 (en) 2000-04-04 2001-10-11 Lintec Corporation Device and method for measuring adhesive strength
CN1114728C (zh) 2000-04-21 2003-07-16 中国石油化工集团公司 止血纤维及其制造方法
EP1149906A1 (en) 2000-04-25 2001-10-31 Pliva, Farmaceutska, Industrija, Dionicko Drustvo Thrombopoietin receptor modulating peptide
CA2407235A1 (en) 2000-04-28 2001-11-08 Fziomed, Inc. Hemostatic compositions of polyacids and polyalkylene oxides and methods for their use
WO2001097826A2 (en) 2000-06-16 2001-12-27 University Of Medicine And Dentistry Of New Jersey Hemostatic compositions, devices and methods
AT411326B (de) 2000-06-20 2003-12-29 Biering Wolfgang Hämostatische collagen-pellets
AT412445B (de) 2000-06-20 2005-03-25 Biering Wolfgang Flüssiges collagen-hämostatikum
AU2001273432A1 (en) 2000-07-13 2002-01-30 Invitrogen Corporation Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix
US6554903B1 (en) 2000-07-19 2003-04-29 Nylok Corporation Unitary spray nozzle
US20030032143A1 (en) 2000-07-24 2003-02-13 Neff Thomas B. Collagen type I and type III compositions for use as an adhesive and sealant
WO2002009792A1 (en) 2000-07-28 2002-02-07 Anika Therapeutics, Inc. Bioabsorbable composites of derivatized hyaluronic acid
US6890342B2 (en) 2000-08-02 2005-05-10 Loma Linda University Method and apparatus for closing vascular puncture using hemostatic material
IT1317358B1 (it) 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Derivati cross-linkati dell'acido ialuronico.
JP2004508137A (ja) 2000-09-12 2004-03-18 ヴァージニア コモンウェルス ユニバーシティ 高圧出血に対する処置
CA2777791A1 (en) 2000-09-18 2002-03-21 Organogenesis Inc. Methods for treating a patient using a bioengineered flat sheet graft prostheses
US6364519B1 (en) 2000-09-26 2002-04-02 Smith & Nephew, Inc. Bone cement system
US6635272B2 (en) 2000-11-09 2003-10-21 Richard N. Leaderman Wound dressing and drug delivery system
US6458380B1 (en) 2000-11-09 2002-10-01 Richard Leaderman Dressing and preparation delivery system
US20030009194A1 (en) 2000-12-07 2003-01-09 Saker Mark B. Tissue tract sealing device
US20020082620A1 (en) 2000-12-27 2002-06-27 Elaine Lee Bioactive materials for aneurysm repair
US7041868B2 (en) 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Bioabsorbable wound dressing
US6733774B2 (en) 2001-01-25 2004-05-11 Nycomed Pharma As Carrier with solid fibrinogen and solid thrombin
US20020164322A1 (en) 2001-01-25 2002-11-07 Alfred Schaufler Suspension comprising fibrinogen, thrombin and alcohol, a method for preparing such a suspension, a method for coating a carrier with such a suspension, a method of drying a coating of a carrier, and a coated collagen sponge
CA2434964C (en) 2001-01-25 2009-04-21 Nycomed Pharma As Carrier with solid fibrinogen and solid thrombin
US7052713B2 (en) 2001-02-13 2006-05-30 Nycomed Pharma As Carrier with solid fibrinogen and solid thrombin
DE60219433D1 (de) 2001-02-14 2007-05-24 Genzyme Corp Biokompatibles vlies für hämostase und gewebeaufbau
US8187625B2 (en) 2001-03-12 2012-05-29 Boston Scientific Scimed, Inc. Cross-linked gelatin composition comprising a wetting agent
TW526069B (en) 2001-04-10 2003-04-01 Sod Conseils Rech Applic Injection device
US6685745B2 (en) 2001-05-15 2004-02-03 Scimed Life Systems, Inc. Delivering an agent to a patient's body
BR0102637A (pt) 2001-05-17 2003-02-25 Johnson & Johnson Ind Com Curativo adesivo
US20050271737A1 (en) 2001-06-07 2005-12-08 Chinea Vanessa I Application of a bioactive agent to a substrate
US6962715B2 (en) 2001-10-24 2005-11-08 Hewlett-Packard Development Company, L.P. Method and dosage form for dispensing a bioactive substance
US7371403B2 (en) 2002-06-14 2008-05-13 Providence Health System-Oregon Wound dressing and method for controlling severe, life-threatening bleeding
US6676987B2 (en) 2001-07-02 2004-01-13 Scimed Life Systems, Inc. Coating a medical appliance with a bubble jet printing head
US20050019399A1 (en) 2001-09-21 2005-01-27 Gina Fischer Controlled release solid dispersions
US20040234602A1 (en) 2001-09-21 2004-11-25 Gina Fischer Polymer release system
JP4668510B2 (ja) 2001-09-29 2011-04-13 持田製薬株式会社 可撓性容器入り局所止血用医薬組成物
JP4112851B2 (ja) 2001-11-27 2008-07-02 テルモ株式会社 2室型プレフィルドシリンジ
US7923431B2 (en) * 2001-12-21 2011-04-12 Ferrosan Medical Devices A/S Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis
DE60234469D1 (de) 2001-12-21 2009-12-31 Ferrosan As Hämostatische garnitur, verfahren zum zubereiten eines hämostatischen mittels und verfahren zur blutstillung
KR100507593B1 (ko) * 2002-02-08 2005-08-10 주식회사 이화양행 액체공급장치
US20060189516A1 (en) 2002-02-19 2006-08-24 Industrial Technology Research Institute Method for producing cross-linked hyaluronic acid-protein bio-composites
CN1635853B (zh) 2002-02-20 2010-05-12 21世纪国际新技术株式会社 施用细小粉末状药物的装置
NZ535136A (en) 2002-02-21 2006-03-31 Encelle Inc Immobilized bioactive hydrogel matrices as surface coatings
WO2003079985A2 (en) 2002-03-18 2003-10-02 Carnegie Mellon University Method and apparatus for preparing biomimetic scaffold
US20050239675A1 (en) * 2002-04-01 2005-10-27 Munzer Makansi Carrier foam to enhance liquid functional performance
CA2485268A1 (en) 2002-05-08 2003-11-20 Rheinisch-Westfaelische Technische Hochschule Aachen (Rwth) Resorbable pharmaceutical formulation for the continuous release of thrombin
US7670623B2 (en) 2002-05-31 2010-03-02 Materials Modification, Inc. Hemostatic composition
US20050137512A1 (en) 2003-12-23 2005-06-23 Campbell Todd D. Wound dressing and method for controlling severe, life-threatening bleeding
US20040120993A1 (en) 2002-12-20 2004-06-24 Guanghui Zhang Hemostatic wound dressing and fabric and methods of making and using same
US20040101546A1 (en) 2002-11-26 2004-05-27 Gorman Anne Jessica Hemostatic wound dressing containing aldehyde-modified polysaccharide and hemostatic agents
US7008403B1 (en) * 2002-07-19 2006-03-07 Cognitive Ventures Corporation Infusion pump and method for use
US7713551B2 (en) 2002-09-11 2010-05-11 Elan Pharma International Ltd. Gel stabilized nanoparticulate active agent compositions
GB2393120A (en) 2002-09-18 2004-03-24 Johnson & Johnson Medical Ltd Compositions for wound treatment
CA2633589A1 (en) 2002-09-26 2004-04-08 Angiotech International Ag Perivascular wraps
US7074425B2 (en) * 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
GB2393655B (en) 2002-09-27 2005-08-24 Johnson & Johnson Medical Ltd Wound treatment device
IL152030A0 (en) 2002-09-30 2003-05-29 Nvr Labs Ltd Neural & Vascular Cohesive biopolymers comprising sulfated polysaccharides and fibrillar proteins and use thereof for tissue repair
US20060258560A1 (en) 2002-09-30 2006-11-16 Chunlin Yang Dry tissue sealant compositions
GB2393656B (en) 2002-10-01 2005-11-16 Johnson & Johnson Medical Ltd Enzyme-sensitive therapeutic wound dressings
US7135027B2 (en) 2002-10-04 2006-11-14 Baxter International, Inc. Devices and methods for mixing and extruding medically useful compositions
ITPD20020271A1 (it) 2002-10-18 2004-04-19 Fidia Farmaceutici Composti chimico-farmaceutici costituiti da derivati dei taxani legati covalentemente all'acido ialuronico o ai suoi derivati.
US20040079763A1 (en) 2002-10-29 2004-04-29 Powell Cindy Hagood Duplex storage pouch
IL152574A (en) 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
JP2004147959A (ja) 2002-10-31 2004-05-27 Nipro Corp 2成分混合型プレフィルドシリンジ
US20060121080A1 (en) 2002-11-13 2006-06-08 Lye Whye K Medical devices having nanoporous layers and methods for making the same
MXPA05006193A (es) 2002-12-11 2005-12-05 Ferrosan As Materiales basados en gelatina como hisopos.
US7699804B2 (en) 2003-01-31 2010-04-20 Creare Inc. Fluid ejection system
GB0304716D0 (en) 2003-02-28 2003-04-02 Uws Ventures Ltd Method for producing partially frozen ice-water-air mixtures
US7112713B2 (en) 2003-03-12 2006-09-26 Gelsus Research And Consulting, Inc. Dressing based on the Teorell-Meyer gradient
US20040181183A1 (en) 2003-03-12 2004-09-16 Sceusa Nicholas A. Bandage based on the teorell-meyer gradient
DK1610768T3 (da) 2003-03-26 2008-09-22 Egalet As Matrikskompositioner til styret afgivelse af lægemiddelsubstanser
US7051654B2 (en) 2003-05-30 2006-05-30 Clemson University Ink-jet printing of viable cells
US8834864B2 (en) 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
WO2004108179A1 (en) 2003-06-05 2004-12-16 Baxter International Inc. Compositions for repairing and regenerating human dura mater
AU2004253463B2 (en) 2003-06-16 2010-12-09 Loma Linda University Medical Center Deployable multifunctional hemostatic agent
CA2529717C (en) 2003-06-16 2013-04-02 Loma Linda University Medical Center Deployable hemostatic agent
US7129210B2 (en) 2003-07-23 2006-10-31 Covalent Medical, Inc. Tissue adhesive sealant
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US20060019868A1 (en) 2004-01-30 2006-01-26 Pendharkar Sanyog M Hemostatic compositions and devices
KR100588614B1 (ko) 2003-11-10 2006-06-13 주식회사 바이오레인 기포를 포함하는 유착방지제
US20050181977A1 (en) 2003-11-10 2005-08-18 Angiotech International Ag Medical implants and anti-scarring agents
JP2005169008A (ja) 2003-12-15 2005-06-30 Nipro Corp 生体適合性材料の滅菌方法
US20050136112A1 (en) 2003-12-19 2005-06-23 Pediamed Pharmaceuticals, Inc. Oral medicament delivery system
US7109163B2 (en) 2004-01-30 2006-09-19 Ethicon, Inc. Hemostatic compositions and devices
RU2377022C9 (ru) 2004-01-30 2010-08-10 Ферросан А/С Гемостатические спреи и композиции
EP1602365A1 (en) 2004-03-03 2005-12-07 Switch Biotech Aktiengesellschaft Pharmaceutical composition for topical use in form of xerogels or films and methods for production
US20050218541A1 (en) 2004-04-02 2005-10-06 Peng Henry T Method of producing interpenetrating polymer network
US20050245905A1 (en) 2004-04-30 2005-11-03 Schmidt Steven P Local drug-delivery system
GB2414021A (en) 2004-05-10 2005-11-16 Johnson & Johnson Medical Ltd Absorbable haemostatic materials
WO2005107713A2 (en) 2004-05-11 2005-11-17 Egalet A/S Swellable dosage form comprising gellan gum
US7393674B2 (en) 2004-06-22 2008-07-01 Zymogenetics, Inc. Thrombin compositions
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
US8119160B2 (en) 2004-06-29 2012-02-21 Ethicon, Inc. Hemostatic compositions and devices
US7968085B2 (en) 2004-07-05 2011-06-28 Ascendis Pharma A/S Hydrogel formulations
KR20070046093A (ko) * 2004-07-09 2007-05-02 훼로산 아크티에 셀스카브 히알루론산을 포함하는 지혈 조성물
WO2006031358A2 (en) 2004-08-13 2006-03-23 Hyperbranch Medical Technology, Inc. Dendritic polymers, crosslinked gels, and their uses as ophthalmic sealants and lenses
US20080091277A1 (en) 2004-08-13 2008-04-17 Kai Deusch Surgical prosthesis having biodegradable and nonbiodegradable regions
US8858978B2 (en) 2004-09-28 2014-10-14 Atrium Medical Corporation Heat cured gel and method of making
WO2006034568A1 (en) 2004-09-30 2006-04-06 Covalon Technologies Inc. Non-adhesive elastic gelatin matrices
ES2226587B1 (es) 2004-10-22 2005-12-16 Probitas Pharma, S.A. Composicion de trombina estable.
EP1833517B1 (en) 2004-12-14 2008-09-24 Fidia Advanced Biopolymers S.R.L. Process for the preparation of two and three dimensional polymer scaffolds
JP2006296896A (ja) 2005-04-22 2006-11-02 Tohoku Univ コラーゲン薄膜シート、その製造方法、それを用いた再建方法、および自己組織再生誘導型人工皮膚・粘膜
US20060255053A1 (en) 2005-05-16 2006-11-16 Empire Industrial Corp. Sealable container
US20090274759A1 (en) 2005-06-03 2009-11-05 Egalet A/S Solid pharmaceutical composition with a first fraction of a dispersion medium and a second fraction of a matrix, the latter being at least partially first exposed to gastrointestinal fluids
US20060282138A1 (en) 2005-06-10 2006-12-14 Ohshin Mlp Co., Ltd. Exothermic structure that is directly applied to skin
WO2007001926A2 (en) 2005-06-24 2007-01-04 Hyperbranch Medical Technology, Inc. Low-swelling hydrogel sealants for wound repair
US20070086958A1 (en) 2005-10-14 2007-04-19 Medafor, Incorporated Formation of medically useful gels comprising microporous particles and methods of use
WO2007059144A1 (en) 2005-11-15 2007-05-24 Surmodics, Inc. Ultrasonic nozzles for applying two-component coatings
EP1962931A2 (en) * 2005-12-21 2008-09-03 Glaxo Group Limited Aerosol canister employing a polymeric film having improved moisture barrier properties
US20070264130A1 (en) 2006-01-27 2007-11-15 Phluid, Inc. Infusion Pumps and Methods for Use
JP5137854B2 (ja) 2006-02-09 2013-02-06 デカ・プロダクツ・リミテッド・パートナーシップ 流体送達システムおよび方法
US20070250007A1 (en) * 2006-04-23 2007-10-25 Nilimedix Ltd. Drug Delivery Device With Air Pressure Spring And Safety Valve
US8496953B2 (en) 2006-05-12 2013-07-30 W. L. Gore & Associates, Inc. Immobilized biologically active entities having a high degree of biological activity following sterilization
US9114194B2 (en) 2006-05-12 2015-08-25 W. L. Gore & Associates, Inc. Immobilized biologically active entities having high biological activity following mechanical manipulation
CN101472624B (zh) 2006-05-12 2013-10-23 戈尔企业控股股份有限公司 机械操作或灭菌后具有高度生物学活性的固定的生物活性实体
US8703122B2 (en) 2006-05-31 2014-04-22 Baxter International Inc. Method for directed cell in-growth and controlled tissue regeneration in spinal surgery
KR100751046B1 (ko) 2006-07-21 2007-08-21 이가식품(주) 수용성 키토산을 함유하는 당면의 제조방법
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
WO2008019126A2 (en) 2006-08-04 2008-02-14 Stb Lifesaving Technologies, Inc. Process for production of solid wound dressing
US20080095830A1 (en) 2006-10-20 2008-04-24 Van Holten Robert W Method for making a dressing
KR20090082468A (ko) 2006-11-09 2009-07-30 케이씨아이 라이센싱 인코포레이티드 상처에 적합한 다공성의 생체흡수성 드레싱 및 그 제조 방법
MX2009006369A (es) 2006-12-15 2010-02-24 Lifebond Ltd Apositos y selladores hemostaticos de gelatina-transglutaminasa.
RU2009127718A (ru) 2006-12-19 2011-01-27 Ферросан А/С (Dk) Раневой или тканевой перевязочный материал, содержащий молочнокислые бактерии
WO2008090555A2 (en) 2007-01-22 2008-07-31 Elutex Ltd. Medical devices having a matrix adhered thereof
WO2008127497A2 (en) 2007-02-21 2008-10-23 The Regents Of The University Of California Hemostatic compositions and methods of use
US20080311172A1 (en) 2007-04-25 2008-12-18 Schapira Jay N Programmed-release, nanostructured biological construct
AU2008266094B2 (en) 2007-06-15 2014-01-30 Baxter International Inc. Stabilized thrombin compositions
WO2009020612A1 (en) 2007-08-06 2009-02-12 Stb Lifesaving Technologies, Inc. Methods and dressing for sealing internal injuries
US20090087569A1 (en) 2007-09-27 2009-04-02 Fenchem Enterprises Ltd. Methods for Preparing Highly Stable Hyaluronic Acid
CN201079602Y (zh) * 2007-10-25 2008-07-02 杨业云 一种瓶装药液快速输液器
US8790698B2 (en) 2007-10-30 2014-07-29 Baxter International Inc. Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects
CN101945678B (zh) 2008-01-17 2013-07-24 贝克顿·迪金森公司 用于使物质混合的阀
CA2717571C (en) 2008-03-03 2016-08-23 Omrix Biopharmaceuticals Ltd. A gelatin sponge comprising an active ingredient, its preparation and use
CA2716010C (en) 2008-04-03 2019-10-01 Zymogenetics, Inc. Hemostatic microspheres
EP2282718A2 (en) 2008-04-25 2011-02-16 Jay N. Schapira Programmed-release, nanostructured biological construct for stimulating cellular engraftment for tissue regeneration
CA2724339C (en) 2008-05-14 2017-08-01 Biolyph, Llc Reagent preparation and dispensing device and methods for the same
US20100048758A1 (en) 2008-08-22 2010-02-25 Boston Scientific Scimed, Inc. Lubricious coating composition for devices
EP2348835A4 (en) * 2008-09-28 2014-01-22 Knc Ner Acquisition Sub Inc MIXES FROM MULTICOLOR CATECHOL COMPOUNDS
DE102008058213A1 (de) * 2008-11-19 2010-05-20 B. Braun Melsungen Ag Anästhesiespritze mit einem längsverschieblichen Vorschubkolben sowie Rückschlagventil mit Durchlass und Sperrrichtung und Verwendung eines O-Rings als Rückschlagventil
DE102009004828B4 (de) 2009-01-13 2010-12-09 Lts Lohmann Therapie-Systeme Ag Injektor mit verdrängbarem Stopfenteil
JP5088342B2 (ja) 2009-03-25 2012-12-05 三菱マテリアル株式会社 多孔質焼結体の製造方法
CN201384747Y (zh) * 2009-04-21 2010-01-20 周卫东 一种手术室用输液瓶快速输液器
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
US8118777B2 (en) * 2009-05-29 2012-02-21 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
WO2010145817A2 (en) 2009-06-16 2010-12-23 Baxter International Inc. Hemostatic sponge
US8429831B2 (en) 2009-09-04 2013-04-30 Abbott Cardiovascular Systems Inc. Drug-eluting coatings applied to medical devices by spraying and drying to remove solvent
WO2011083154A1 (en) 2010-01-08 2011-07-14 Profibrix Bv Dry powder fibrin sealant
JP2011212182A (ja) 2010-03-31 2011-10-27 Terumo Corp プレフィルドシリンジ
EP2575776B1 (en) 2010-06-01 2018-05-30 Baxter International Inc Process for making dry and stable hemostatic compositions
BR112012030463B1 (pt) 2010-06-01 2021-08-24 Baxter International Inc. Processo para fabricar uma composição hemostática seca e estável, recipiente acabado final, kit para administrar uma composição hemostática, e, grânulos revestidos com trombina
WO2011151384A1 (en) 2010-06-01 2011-12-08 Baxter International Inc. Process for making dry and stable hemostatic compositions
US9283187B2 (en) 2011-04-27 2016-03-15 Biom'up Hemostatic compositions
RU2013155713A (ru) 2011-07-06 2015-08-20 Профибрикс Бв Составы для лечения ран
US20130090291A1 (en) 2011-10-11 2013-04-11 Baxter Healthcare S.A. Hemostatic compositions
EP4137166A1 (en) 2011-10-11 2023-02-22 Baxter International Inc Hemostatic compositions
MX356185B (es) 2011-10-11 2018-05-17 Baxter Int Composiciones hemostaticas.
TWI548417B (zh) 2011-10-27 2016-09-11 巴克斯特國際公司 止血組成物
BR112014030962A2 (pt) 2012-06-12 2017-06-27 Ferrosan Medical Devices As métodos para preparação e para reconstituição de uma composição seca adequada para uso em hemostase e cicatrização de feridas, e, kit hemostático
KR102199092B1 (ko) 2012-12-07 2021-01-07 백스터 인터내셔널 인코포레이티드 지혈 폼
JP6390873B2 (ja) 2013-06-21 2018-09-19 フェッローサン メディカル ディバイス エー/エス 減圧膨張させた乾燥組成物およびそれを保持するためのシリンジ
WO2015086028A1 (en) 2013-12-11 2015-06-18 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
WO2016058612A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
WO2016102446A1 (en) 2014-12-24 2016-06-30 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
RU2717356C2 (ru) 2015-07-03 2020-03-23 Ферросан Медикал Дивайсиз А/С Шприц для удерживания вакуума в состоянии хранения
IL242984A0 (en) 2015-12-08 2016-02-29 Omrix Biopharmaceuticals Ltd Thrombin microcapsules, their preparation and how to use them

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983001244A1 (en) * 1981-10-06 1983-04-14 Frutin, Bernard, Derek Pressurized dispensing apparatus
US4887743A (en) * 1987-06-10 1989-12-19 Blake William S Aerosol valve
US6861046B1 (en) * 1993-08-18 2005-03-01 Dow Corning France Device for dispensing a therapeutic or cosmetic substance onto the skin and a method of skin treatment
RU2244519C2 (ru) * 1999-06-16 2005-01-20 Л.И.К.А. С.Р.Л. Устройство для осуществления микроабразивной обработки ткани человека и способ работы устройства для осуществления микроабразивной обработки ткани человека
EP2040724B1 (en) * 2006-05-18 2011-10-05 Biobalance Llc Biotherapeutic compositions comprising probiotic escherichia coli and metronidazole and uses thereof
WO2009109194A2 (en) * 2008-02-29 2009-09-11 Ferrosan A/S Device for promotion of hemostasis and/or wound healing
US20100256671A1 (en) * 2009-04-07 2010-10-07 Biomedica Management Corporation Tissue sealant for use in noncompressible hemorrhage
WO2011047753A1 (en) * 2009-10-19 2011-04-28 Ferrosan Medical Devices A/S Malleable tip for agent applicator to a target site

Also Published As

Publication number Publication date
WO2013131520A2 (en) 2013-09-12
JP6241624B2 (ja) 2017-12-06
CA2865349A1 (en) 2013-09-12
WO2013131520A3 (en) 2013-10-24
HK1204904A1 (en) 2015-12-11
IN2014DN08122A (en:Method) 2015-05-01
EP2822474A2 (en) 2015-01-14
RU2014140147A (ru) 2016-04-27
US11109849B2 (en) 2021-09-07
CN104159527A (zh) 2014-11-19
CN104159527B (zh) 2017-04-12
US20150045830A1 (en) 2015-02-12
EP2822474B1 (en) 2018-05-02
CA2865349C (en) 2021-07-06
JP2015509408A (ja) 2015-03-30

Similar Documents

Publication Publication Date Title
RU2657955C2 (ru) Контейнер под давлением, содержащий гемостатическую пасту
EP1633427B1 (en) Improved disposable applicator for topical composition
CN102341311B (zh) 具有软管的排料装置
US8608030B2 (en) Cartridge system with compressed gas cartridge
US10219793B2 (en) Delivery systems for flowable substances stored in squeezable containers
JP4477634B2 (ja) 2つの流体、特に接着剤成分を供給するためのデュアルエンドアプリケータ
EP2790769B1 (en) Antiseptic applicator
EP2202179A1 (en) Dispensing device for viscous materials
US10342733B2 (en) Flexible, flat pouch with port for mixing and delivering powder-liquid mixture
US8790031B2 (en) Antiseptic applicator
US6874967B1 (en) Applicator with sealed fluid
AU2014241894A1 (en) Automatic three-way diverter valve
HK1204904B (en) Pressurized container containing haemostatic paste
US20250099683A1 (en) Fluid Adhesive Dispenser Device for IV Port Securement or Wound Closure
US20240366876A1 (en) Applicator tips useful for surgical application of a viscous substance
EP3318196A1 (en) A liquid dispenser