RU2472791C2 - Соединения, модулирующие внутриклеточный кальций - Google Patents

Соединения, модулирующие внутриклеточный кальций Download PDF

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RU2472791C2
RU2472791C2 RU2011108969/04A RU2011108969A RU2472791C2 RU 2472791 C2 RU2472791 C2 RU 2472791C2 RU 2011108969/04 A RU2011108969/04 A RU 2011108969/04A RU 2011108969 A RU2011108969 A RU 2011108969A RU 2472791 C2 RU2472791 C2 RU 2472791C2
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compound according
disease
alkyl
phenyl
compound
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RU2011108969A (ru
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Гонул ВЕЛИСЕЛЕБИ
Кеннет А. СТОДЕРМАН
Джеффри П. УИТТЕН
Яжонг ПЕЙ
Цзяньгуо ЦАО
Чжицзунь ВАНГ
Эван РОДЖЕРС
Брайан Дик
Джонатан ГРЕЙ
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КалсиМедика Инк.
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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RU2011108969/04A 2008-08-27 2009-08-26 Соединения, модулирующие внутриклеточный кальций RU2472791C2 (ru)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US9236408P 2008-08-27 2008-08-27
US61/092,364 2008-08-27
US14284609P 2009-01-06 2009-01-06
US61/142,846 2009-01-06
US14373909P 2009-01-09 2009-01-09
US61/143,739 2009-01-09
US15727409P 2009-03-04 2009-03-04
US61/157,274 2009-03-04
US15870209P 2009-03-09 2009-03-09
US15871009P 2009-03-09 2009-03-09
US61/158,702 2009-03-09
US61/158,710 2009-03-09
PCT/US2009/055090 WO2010027875A2 (en) 2008-08-27 2009-08-26 Compounds that modulate intracellular calcium

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RU2011108969A RU2011108969A (ru) 2012-10-10
RU2472791C2 true RU2472791C2 (ru) 2013-01-20

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US (7) US7981925B2 (enExample)
EP (1) EP2321303B1 (enExample)
JP (1) JP5782377B2 (enExample)
KR (1) KR101724161B1 (enExample)
CN (1) CN102256969A (enExample)
AU (1) AU2009288245B2 (enExample)
BR (1) BRPI0917719A2 (enExample)
CA (1) CA2734500A1 (enExample)
IL (1) IL211391B (enExample)
MX (1) MX2011002149A (enExample)
MY (1) MY157445A (enExample)
RU (1) RU2472791C2 (enExample)
TW (1) TWI392673B (enExample)
WO (2) WO2010027875A2 (enExample)
ZA (1) ZA201101335B (enExample)

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JP5411141B2 (ja) 2007-09-10 2014-02-12 カルシメディカ，インク． 細胞内カルシウムを調節する化合物
CA2734500A1 (en) * 2008-08-27 2010-03-11 Calcimedica Inc. Compounds that modulate intracellular calcium
US8524763B2 (en) * 2008-09-22 2013-09-03 Calcimedica, Inc. Inhibitors of store operated calcium release
US8618307B2 (en) * 2009-09-16 2013-12-31 Calcimedica, Inc. Compounds that modulate intracellular calcium
US8993612B2 (en) 2009-10-08 2015-03-31 Rhizen Pharmaceuticals Sa Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer
US8377970B2 (en) 2009-10-08 2013-02-19 Rhizen Pharmaceuticals Sa Modulators of calcium release-activated calcium channel
EP2947073B1 (en) 2009-10-22 2019-04-03 Fibrotech Therapeutics Pty Ltd Fused ring analogues of anti-fibrotic agents
US10703722B2 (en) 2010-04-27 2020-07-07 Calcimedica, Inc. Compounds that modulate intracellular calcium
TWI504404B (zh) * 2010-07-22 2015-10-21 Univ Kaohsiung Medical 用於抑制結腸直腸癌細胞及子宮上皮癌細胞生長轉移之醫藥組合物
CN103180316A (zh) * 2010-08-27 2013-06-26 钙医学公司 调节细胞内钙的化合物
EP2619200A4 (en) * 2010-09-22 2014-10-15 Calcimedica Inc COMPOUNDS AS MODULATORS OF INTRA CELLULAR CALCIUM
PL2632906T3 (pl) 2010-10-30 2016-09-30 Oksazolinowe i izoksazolinowe pochodne jako modulatory kanałów typu CRAC
US9399638B2 (en) 2012-05-02 2016-07-26 Lupin Limited Substituted pyridine compounds as CRAC modulators
CA2871222A1 (en) 2012-05-02 2013-11-07 Lupin Limited Substituted pyrazole compounds as crac modulators
WO2014030600A1 (ja) * 2012-08-20 2014-02-27 マナック株式会社 ボリン酸誘導体の製造方法及び新規ボリン酸誘導体
US9512116B2 (en) 2012-10-12 2016-12-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
GB201302927D0 (en) 2013-02-20 2013-04-03 Cancer Therapeutics Crc Pty Ltd Compounds
US9725463B2 (en) 2013-06-21 2017-08-08 Lupin Limited Substituted heterocyclic compounds as CRAC modulators
US9790231B2 (en) 2013-06-24 2017-10-17 Lupin Limited Chromane and chromene derivatives and their use as CRAC modulators
BR112016030690B1 (pt) 2014-06-27 2023-11-14 Nogra Pharma Limited Compostos moduladores do receptor de arila, composição farmacêutica compreendendo os mesmos e usos terapêuticos dos ditos compostos
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KR20110059723A (ko) 2011-06-03
IL211391B (en) 2018-10-31
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US20130231344A1 (en) 2013-09-05
RU2011108969A (ru) 2012-10-10
WO2010027875A2 (en) 2010-03-11
KR101724161B1 (ko) 2017-04-06
US7981925B2 (en) 2011-07-19
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JP2012501337A (ja) 2012-01-19
CN102256969A (zh) 2011-11-23
CA2734500A1 (en) 2010-03-11
AU2009288245A1 (en) 2010-03-11
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ZA201101335B (en) 2011-10-26
MX2011002149A (es) 2011-04-05
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