KR101724161B1 - 세포내 칼슘을 조절하는 화합물 - Google Patents
세포내 칼슘을 조절하는 화합물 Download PDFInfo
- Publication number
- KR101724161B1 KR101724161B1 KR1020117006529A KR20117006529A KR101724161B1 KR 101724161 B1 KR101724161 B1 KR 101724161B1 KR 1020117006529 A KR1020117006529 A KR 1020117006529A KR 20117006529 A KR20117006529 A KR 20117006529A KR 101724161 B1 KR101724161 B1 KR 101724161B1
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- South Korea
- Prior art keywords
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- thiophene
- another embodiment
- carboxylic acid
- methoxybenzamido
- Prior art date
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- 0 *OC(CC#N)=O Chemical compound *OC(CC#N)=O 0.000 description 9
- XISARODQCFVLQN-UHFFFAOYSA-N C=[O]=C(C(CC(CC=C=C1)=C1Cl)Cl)Cl Chemical compound C=[O]=C(C(CC(CC=C=C1)=C1Cl)Cl)Cl XISARODQCFVLQN-UHFFFAOYSA-N 0.000 description 1
- LKUHRNFFSKFCAQ-UHFFFAOYSA-N CC(C)(C)OC(c1c(N)[s]cc1-c(cc1)ccc1Cl)=O Chemical compound CC(C)(C)OC(c1c(N)[s]cc1-c(cc1)ccc1Cl)=O LKUHRNFFSKFCAQ-UHFFFAOYSA-N 0.000 description 1
- JCKGIVGMIBQPNW-XYOKQWHBSA-N CC(CC1=CC(C)CC=C1)C(N/C(/SBr)=C\C(O)=O)=O Chemical compound CC(CC1=CC(C)CC=C1)C(N/C(/SBr)=C\C(O)=O)=O JCKGIVGMIBQPNW-XYOKQWHBSA-N 0.000 description 1
- OWAWAFKVPTWIBP-UHFFFAOYSA-N CC(Cc1ccccc1)C(Cl)=O Chemical compound CC(Cc1ccccc1)C(Cl)=O OWAWAFKVPTWIBP-UHFFFAOYSA-N 0.000 description 1
- IXHMQCSLZGMNAD-UHFFFAOYSA-O CCC(NC(C(CC1)=Cc2c1nc(C)cc2C[IH+])=O)=C Chemical compound CCC(NC(C(CC1)=Cc2c1nc(C)cc2C[IH+])=O)=C IXHMQCSLZGMNAD-UHFFFAOYSA-O 0.000 description 1
- KZEOBHBHZBLUQG-UHFFFAOYSA-N CCOC(C)c1c(N)[s]cc1-c(cc1)ccc1Br Chemical compound CCOC(C)c1c(N)[s]cc1-c(cc1)ccc1Br KZEOBHBHZBLUQG-UHFFFAOYSA-N 0.000 description 1
- CVZZNRXMDCOHBG-UHFFFAOYSA-N NC(Cc(cccc1)c1Cl)C(O)=O Chemical compound NC(Cc(cccc1)c1Cl)C(O)=O CVZZNRXMDCOHBG-UHFFFAOYSA-N 0.000 description 1
- NNNCLKMRCLOGRU-UHFFFAOYSA-N OC(C(Cc1ccccc1Cl)Cl)=O Chemical compound OC(C(Cc1ccccc1Cl)Cl)=O NNNCLKMRCLOGRU-UHFFFAOYSA-N 0.000 description 1
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9236408P | 2008-08-27 | 2008-08-27 | |
| US61/092,364 | 2008-08-27 | ||
| US14284609P | 2009-01-06 | 2009-01-06 | |
| US61/142,846 | 2009-01-06 | ||
| US14373909P | 2009-01-09 | 2009-01-09 | |
| US61/143,739 | 2009-01-09 | ||
| US15727409P | 2009-03-04 | 2009-03-04 | |
| US61/157,274 | 2009-03-04 | ||
| US15870209P | 2009-03-09 | 2009-03-09 | |
| US15871009P | 2009-03-09 | 2009-03-09 | |
| US61/158,710 | 2009-03-09 | ||
| US61/158,702 | 2009-03-09 | ||
| PCT/US2009/055090 WO2010027875A2 (en) | 2008-08-27 | 2009-08-26 | Compounds that modulate intracellular calcium |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20110059723A KR20110059723A (ko) | 2011-06-03 |
| KR101724161B1 true KR101724161B1 (ko) | 2017-04-06 |
Family
ID=41722281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020117006529A Expired - Fee Related KR101724161B1 (ko) | 2008-08-27 | 2009-08-26 | 세포내 칼슘을 조절하는 화합물 |
Country Status (15)
| Country | Link |
|---|---|
| US (7) | US7906553B2 (enExample) |
| EP (1) | EP2321303B1 (enExample) |
| JP (1) | JP5782377B2 (enExample) |
| KR (1) | KR101724161B1 (enExample) |
| CN (1) | CN102256969A (enExample) |
| AU (1) | AU2009288245B2 (enExample) |
| BR (1) | BRPI0917719A2 (enExample) |
| CA (1) | CA2734500A1 (enExample) |
| IL (1) | IL211391B (enExample) |
| MX (1) | MX2011002149A (enExample) |
| MY (1) | MY157445A (enExample) |
| RU (1) | RU2472791C2 (enExample) |
| TW (1) | TWI392673B (enExample) |
| WO (2) | WO2010027875A2 (enExample) |
| ZA (1) | ZA201101335B (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101257550B1 (ko) | 2007-09-10 | 2013-04-24 | 칼시메디카, 인크 | 세포내 칼슘을 조절하는 화합물 |
| CN102256969A (zh) * | 2008-08-27 | 2011-11-23 | 钙医学公司 | 调节胞内钙的化合物 |
| US8524763B2 (en) * | 2008-09-22 | 2013-09-03 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
| WO2011034962A2 (en) * | 2009-09-16 | 2011-03-24 | Calcimedica Inc. | Compounds that modulate intracellular calcium |
| US8377970B2 (en) | 2009-10-08 | 2013-02-19 | Rhizen Pharmaceuticals Sa | Modulators of calcium release-activated calcium channel |
| US8993612B2 (en) | 2009-10-08 | 2015-03-31 | Rhizen Pharmaceuticals Sa | Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer |
| EP2947073B1 (en) * | 2009-10-22 | 2019-04-03 | Fibrotech Therapeutics Pty Ltd | Fused ring analogues of anti-fibrotic agents |
| US10703722B2 (en) | 2010-04-27 | 2020-07-07 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| TWI504404B (zh) * | 2010-07-22 | 2015-10-21 | Univ Kaohsiung Medical | 用於抑制結腸直腸癌細胞及子宮上皮癌細胞生長轉移之醫藥組合物 |
| US9079891B2 (en) * | 2010-08-27 | 2015-07-14 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
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2009
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- 2009-08-26 MY MYPI2011000865A patent/MY157445A/en unknown
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- 2009-08-26 JP JP2011525178A patent/JP5782377B2/ja not_active Expired - Fee Related
- 2009-08-26 TW TW098128758A patent/TWI392673B/zh not_active IP Right Cessation
- 2009-08-26 KR KR1020117006529A patent/KR101724161B1/ko not_active Expired - Fee Related
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- 2009-08-26 AU AU2009288245A patent/AU2009288245B2/en not_active Ceased
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- 2009-08-27 WO PCT/US2009/055247 patent/WO2010025295A2/en not_active Ceased
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2013
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