MX2023001328A - Compuestos de tiofeno para su uso en el tratamiento de la fibrosis renal. - Google Patents

Compuestos de tiofeno para su uso en el tratamiento de la fibrosis renal.

Info

Publication number
MX2023001328A
MX2023001328A MX2023001328A MX2023001328A MX2023001328A MX 2023001328 A MX2023001328 A MX 2023001328A MX 2023001328 A MX2023001328 A MX 2023001328A MX 2023001328 A MX2023001328 A MX 2023001328A MX 2023001328 A MX2023001328 A MX 2023001328A
Authority
MX
Mexico
Prior art keywords
treatment
renal fibrosis
thiophen
compounds
thiophen compounds
Prior art date
Application number
MX2023001328A
Other languages
English (en)
Inventor
Raphaël Darteil
Eric Meldrum
Jacky Vonderscher
Corre Stéphanie Le
Fabiola Terzi
Original Assignee
Enyo Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enyo Pharma filed Critical Enyo Pharma
Publication of MX2023001328A publication Critical patent/MX2023001328A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La presente invención se refiere a un método para tratar la fibrosis renal.
MX2023001328A 2020-08-05 2021-08-05 Compuestos de tiofeno para su uso en el tratamiento de la fibrosis renal. MX2023001328A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20305901 2020-08-05
PCT/EP2021/071829 WO2022029210A1 (en) 2020-08-05 2021-08-05 Thiophen compounds for use in the treatment of renal fibrosis

Publications (1)

Publication Number Publication Date
MX2023001328A true MX2023001328A (es) 2023-03-06

Family

ID=72145328

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023001328A MX2023001328A (es) 2020-08-05 2021-08-05 Compuestos de tiofeno para su uso en el tratamiento de la fibrosis renal.

Country Status (10)

Country Link
US (1) US20230321033A1 (es)
EP (1) EP4192448A1 (es)
JP (1) JP2023537019A (es)
KR (1) KR20230048361A (es)
CN (1) CN116056695A (es)
AU (1) AU2021319876A1 (es)
CA (1) CA3185691A1 (es)
IL (1) IL299972A (es)
MX (1) MX2023001328A (es)
WO (1) WO2022029210A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021377248A1 (en) 2020-11-13 2023-06-22 Inipharm, Inc. Dichlorophenol hsd17b13 inhibitors and uses thereof
US20240208929A1 (en) * 2021-04-05 2024-06-27 Inipharm, Inc. Hydroxypyridine hsd17b13 inhibitors and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2007083689A1 (ja) * 2006-01-19 2009-06-11 株式会社レナサイエンス プラスミノーゲンアクチベーターインヒビター−１阻害剤
TWI392673B (zh) * 2008-08-27 2013-04-11 Calcimedica Inc 調控細胞內鈣離子濃度之化合物
MX2020007917A (es) 2018-02-08 2020-10-28 Enyo Pharma Derivados de tiofeno no condensados y sus usos.

Also Published As

Publication number Publication date
CN116056695A (zh) 2023-05-02
WO2022029210A1 (en) 2022-02-10
US20230321033A1 (en) 2023-10-12
JP2023537019A (ja) 2023-08-30
EP4192448A1 (en) 2023-06-14
CA3185691A1 (en) 2022-02-10
IL299972A (en) 2023-03-01
KR20230048361A (ko) 2023-04-11
AU2021319876A1 (en) 2023-02-16

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