RU2448106C2 - Новые гетероарил-замещенные бензотиазолы - Google Patents

Новые гетероарил-замещенные бензотиазолы Download PDF

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Publication number
RU2448106C2
RU2448106C2 RU2008130965/04A RU2008130965A RU2448106C2 RU 2448106 C2 RU2448106 C2 RU 2448106C2 RU 2008130965/04 A RU2008130965/04 A RU 2008130965/04A RU 2008130965 A RU2008130965 A RU 2008130965A RU 2448106 C2 RU2448106 C2 RU 2448106C2
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Russia
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compound according
disease
alzheimer
compound
atoms
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RU2008130965/04A
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English (en)
Russian (ru)
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RU2008130965A (ru
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Ильва ГРАВЕНФОРС (SE)
Ильва Гравенфорс
Катрин ЙОНАССОН (SE)
Катрин ЙОНАССОН
Йонас МАЛЬМСТРЁМ (SE)
Йонас МАЛЬМСТРЁМ
Гуннар НОРДВАЛЛЬ (SE)
Гуннар Нордвалль
Давид ПИРИНГ (SE)
Давид ПИРИНГ
Кан СЛИВО (SE)
Кан СЛИВО
Даниэль СОН (SE)
Даниэль Сон
Петер СТРЁМ (SE)
Петер СТРЁМ
Давид ВЕНСБО (SE)
Давид Венсбо
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Астразенека Аб
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
RU2008130965/04A 2006-01-27 2007-01-25 Новые гетероарил-замещенные бензотиазолы RU2448106C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76265406P 2006-01-27 2006-01-27
US60/762,654 2006-01-27

Publications (2)

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RU2008130965A RU2008130965A (ru) 2010-03-10
RU2448106C2 true RU2448106C2 (ru) 2012-04-20

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US (2) US8163928B2 (https=)
EP (1) EP1981883A4 (https=)
JP (1) JP5289061B2 (https=)
KR (1) KR101406248B1 (https=)
CN (1) CN101410393B (https=)
AR (1) AR059178A1 (https=)
AU (1) AU2007207904C1 (https=)
BR (1) BRPI0707283A2 (https=)
CA (1) CA2640213A1 (https=)
EC (1) ECSP088645A (https=)
IL (1) IL192876A0 (https=)
NO (1) NO20083394L (https=)
NZ (1) NZ569667A (https=)
RU (1) RU2448106C2 (https=)
SA (1) SA07280009B1 (https=)
TW (2) TW200736252A (https=)
UA (1) UA95267C2 (https=)
UY (1) UY30112A1 (https=)
WO (1) WO2007086800A1 (https=)
ZA (1) ZA200806075B (https=)

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EP2501696B1 (en) 2009-10-15 2016-12-28 Guerbet Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases
JP6069661B2 (ja) 2010-06-24 2017-02-01 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 種々のアミロイドβペプチドアロフォームレベルの調節における組成物及びその使用
CN106729771A (zh) 2011-04-21 2017-05-31 加利福尼亚大学董事会 官能化磁性纳米颗粒及在淀粉样沉积物和神经原纤维缠结成像中用途
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CN102558091B (zh) * 2011-12-22 2014-10-08 合肥工业大学 一种苯并噻唑类衍生物及其用途
CN102659772B (zh) * 2012-05-03 2015-02-11 北京师范大学 一种与Aβ斑块有亲和力的2-芳基苯并杂环化合物及其制备方法和应用
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Publication number Publication date
CA2640213A1 (en) 2007-08-02
EP1981883A4 (en) 2010-10-06
KR20080090542A (ko) 2008-10-08
US8163928B2 (en) 2012-04-24
AU2007207904A1 (en) 2007-08-02
JP2009528271A (ja) 2009-08-06
KR101406248B1 (ko) 2014-06-19
TW201018678A (en) 2010-05-16
UY30112A1 (es) 2007-08-31
AU2007207904C1 (en) 2011-10-13
ZA200806075B (en) 2012-12-27
CN101410393A (zh) 2009-04-15
EP1981883A1 (en) 2008-10-22
AU2007207904B2 (en) 2011-03-10
NZ569667A (en) 2011-09-30
BRPI0707283A2 (pt) 2011-04-26
UA95267C2 (en) 2011-07-25
JP5289061B2 (ja) 2013-09-11
CN101410393B (zh) 2012-01-25
NO20083394L (no) 2008-10-02
WO2007086800A1 (en) 2007-08-02
US8957215B2 (en) 2015-02-17
IL192876A0 (en) 2009-02-11
US20120207679A1 (en) 2012-08-16
ECSP088645A (es) 2008-08-29
AR059178A1 (es) 2008-03-12
TW200736252A (en) 2007-10-01
RU2008130965A (ru) 2010-03-10
US20090028787A1 (en) 2009-01-29
SA07280009B1 (ar) 2011-07-20

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