JP2009541309A5 - - Google Patents
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- Publication number
- JP2009541309A5 JP2009541309A5 JP2009516443A JP2009516443A JP2009541309A5 JP 2009541309 A5 JP2009541309 A5 JP 2009541309A5 JP 2009516443 A JP2009516443 A JP 2009516443A JP 2009516443 A JP2009516443 A JP 2009516443A JP 2009541309 A5 JP2009541309 A5 JP 2009541309A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- fluoroalkyl
- nhc
- methoxy
- benzoxazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(C)*C1CCCCC1 Chemical compound CC(C)*C1CCCCC1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81493606P | 2006-06-19 | 2006-06-19 | |
| US60/814,936 | 2006-06-19 | ||
| PCT/SE2007/000591 WO2007149030A1 (en) | 2006-06-19 | 2007-06-18 | Novel heteroaryl substituted benzoxazoles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009541309A JP2009541309A (ja) | 2009-11-26 |
| JP2009541309A5 true JP2009541309A5 (https=) | 2010-08-05 |
| JP5548842B2 JP5548842B2 (ja) | 2014-07-16 |
Family
ID=38833677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009516443A Expired - Fee Related JP5548842B2 (ja) | 2006-06-19 | 2007-06-18 | 新規なヘテロアリール置換ベンゾオキサゾール |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7670591B2 (https=) |
| EP (1) | EP2035418A1 (https=) |
| JP (1) | JP5548842B2 (https=) |
| KR (1) | KR20090021224A (https=) |
| CN (1) | CN101506201B (https=) |
| AR (1) | AR061515A1 (https=) |
| AU (1) | AU2007261786A1 (https=) |
| CA (1) | CA2655084A1 (https=) |
| CL (1) | CL2007001784A1 (https=) |
| IL (1) | IL195669A0 (https=) |
| MX (1) | MX2008015718A (https=) |
| NO (1) | NO20090201L (https=) |
| TW (1) | TW200813035A (https=) |
| UY (1) | UY30419A1 (https=) |
| WO (1) | WO2007149030A1 (https=) |
| ZA (1) | ZA200810163B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201018678A (en) | 2006-01-27 | 2010-05-16 | Astrazeneca Ab | Novel heteroaryl substituted benzothiazoles |
| TW200901998A (en) | 2007-03-06 | 2009-01-16 | Astrazeneca Ab | Novel 2-heteroaryl substituted benzothiophenes and benzofuranes |
| AU2009260519A1 (en) | 2008-05-30 | 2009-12-23 | Merck Sharp & Dohme Corp. | Novel substituted azabenzoxazoles |
| CA2741668A1 (en) * | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel substituted azabenzoxazoles |
| EP2608672B1 (en) * | 2010-08-23 | 2020-12-16 | Syntrix Biosystems, Inc. | Aminopyridine- and aminopyrimidinecarboxamides as cxcr2 modulators |
| WO2012080729A2 (en) * | 2010-12-14 | 2012-06-21 | Electrophoretics Limited | CASEIN KINASE 1δ (CK1δ) INHIBITORS |
| JPWO2014132919A1 (ja) * | 2013-02-28 | 2017-02-02 | 国立大学法人京都大学 | 診断用組成物 |
| KR101499329B1 (ko) * | 2013-06-17 | 2015-03-06 | 주식회사 대웅제약 | (2-(3,4-다이메톡시페닐)-5-(3-메톡시프로필)벤조퓨란)의결정형 및 이의 제조방법 |
| JP6149684B2 (ja) * | 2013-10-21 | 2017-06-21 | ブラザー工業株式会社 | 携帯端末、画像処理装置、及びプログラム |
| CN106068619B (zh) * | 2014-01-24 | 2019-11-19 | 华为技术有限公司 | 用于进行交叉极化干扰抑制的方法和设备 |
| CN104059028B (zh) * | 2014-06-06 | 2020-10-16 | 北京智博高科生物技术有限公司 | 与Aβ斑块具有亲和力的含手性侧链取代的氟代2-芳基苯并杂环化合物、其制备方法及应用 |
| KR101709731B1 (ko) * | 2015-05-22 | 2017-02-23 | 한국과학기술연구원 | 벤조옥사졸 또는 벤조티아졸 화합물, 그의 제조, 및 용도 |
| US10324943B2 (en) * | 2015-08-10 | 2019-06-18 | Business Objects Software, Ltd. | Auto-monitoring and adjustment of dynamic data visualizations |
| CA2994178C (en) * | 2015-08-18 | 2024-03-19 | The Regents Of The University Of California | Nitroxide containing amyloid binding agents for imaging and therapeutic uses |
| KR101812424B1 (ko) * | 2016-12-28 | 2017-12-27 | 충북대학교 산학협력단 | 2-(2-아미노-5-(1-(피퍼리딘-4-일)-1H-피라졸-3-일)피리딘-3-일)벤조[d]옥사졸-6-올 및 이를 유효성분으로 포함하는 치매의 예방 및 치료용 조성물 |
| EP4097092A1 (en) * | 2020-01-28 | 2022-12-07 | Protego Biopharma, Inc. | Compounds, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU523040B2 (en) | 1978-05-15 | 1982-07-08 | Kanebo Limited | Calcium -antagonistic composition |
| GB8305245D0 (en) | 1983-02-25 | 1983-03-30 | Fujisawa Pharmaceutical Co | Imidazo-heterocyclic compounds |
| JPS6394248A (ja) * | 1986-10-08 | 1988-04-25 | Canon Inc | 電子写真感光体 |
| CA2034309C (en) | 1990-01-22 | 1997-04-01 | Takashi Iwaki | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus |
| JPH09507071A (ja) | 1993-12-21 | 1997-07-15 | イーライ・リリー・アンド・カンパニー | アミロイド原性ペプチドに関連した状態を治療又は予防する方法 |
| US5518713A (en) * | 1995-02-13 | 1996-05-21 | 3V Inc. | Benzoxazole derivatives, the use thereof as sunscreens and cosmetic compositions containing them |
| JPH11116476A (ja) | 1997-10-16 | 1999-04-27 | Sankyo Co Ltd | 縮合複素環化合物 |
| RU2324686C2 (ru) | 2000-08-24 | 2008-05-20 | Юнивесити Оф Питсбэг | ПРОИЗВОДНЫЕ ТИОФЛАВИНА, СВЯЗЫВАЮЩИЕ АМИЛОИД, СПОСОБ ОБНАРУЖЕНИЯ in vivo ОТЛОЖЕНИЙ АМИЛОИДА И СПОСОБ РАСПОЗНАВАНИЯ БОЛЕЗНИ АЛЬЦГЕЙМЕРА |
| WO2002051821A1 (en) | 2000-12-22 | 2002-07-04 | Astrazeneca Ab | Therapeutic compounds |
| US6596731B2 (en) | 2001-03-27 | 2003-07-22 | Hoffmann-La Roche Inc. | Substituted imidazo[1,2-A] pyridine derivatives |
| CA2444214A1 (en) | 2001-04-23 | 2002-10-31 | The Trustees Of The University Of Pennsylvania | Amyloid plaque aggregation inhibitors and diagnostic imaging agents |
| EP1460067A4 (en) * | 2001-11-26 | 2005-12-07 | Takeda Pharmaceutical | BICYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE |
| GB0130305D0 (en) | 2001-12-19 | 2002-02-06 | Amersham Plc | Compounds for imaging alzheimers disease |
| WO2003106439A1 (ja) | 2002-06-12 | 2003-12-24 | 株式会社ビーエフ研究所 | アミロイド蓄積性疾患の画像診断プローブ化合物、老人斑／びまん性老人斑染色用化合物、ならびにアミロイド蓄積性疾患の治療薬 |
| TW200401194A (en) | 2002-07-11 | 2004-01-16 | Advanced Micro Devices Inc | Method and apparatus for determining a processor state without interrupting processor operation |
| ATE425753T1 (de) | 2002-08-02 | 2009-04-15 | Genesoft Pharmaceuticals Inc | Biaryl-verbindungen mit antiinfektiver wirkung |
| JP2004250411A (ja) | 2003-02-21 | 2004-09-09 | Bf Kenkyusho:Kk | アミロイドβ蓄積性疾患の診断プローブおよび治療用化合物 |
| CA2438032C (en) | 2003-03-14 | 2013-05-07 | University Of Pittsburgh | Benzothiazole derivative compounds, compositions and uses |
| WO2004087641A1 (ja) | 2003-03-31 | 2004-10-14 | Daiichi Pharmaceutical Co., Ltd. | ヒドラゾン誘導体 |
| KR100710453B1 (ko) | 2003-05-13 | 2007-04-24 | 에프. 호프만-라 로슈 아게 | 아데노신 수용체 리간드로서의 2-이미다조-벤조싸이아졸 |
| AU2005270026A1 (en) | 2004-07-02 | 2006-02-09 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Use of thioflavin radiolabeled derivatives in amyloid imaging for assessing anti-amyloid therapies |
| GB0420722D0 (en) | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| CA2609980C (en) | 2005-05-27 | 2015-10-13 | Queen's University At Kingston | Treatment of protein folding disorders |
| US20080219922A1 (en) | 2005-09-12 | 2008-09-11 | Goodman Mark M | Alzheimer's Disease Imaging Agents |
| CN101355940B (zh) | 2005-09-16 | 2013-03-27 | 匹兹堡大学高等教育联邦体系 | 用于检测具有至少一种促淀粉样变蛋白的淀粉样沉积物的体内或体外方法 |
| ATE539069T1 (de) | 2005-10-11 | 2012-01-15 | Univ Pittsburgh | Isotopenmarkierte benzofuranverbindungen als bilddarstellende mittel für amyloidogene proteine |
| WO2007063946A1 (ja) | 2005-11-30 | 2007-06-07 | Fujifilm Ri Pharma Co., Ltd. | アミロイドの凝集及び／又は沈着に起因する疾患の診断薬及び治療薬 |
| TW201018678A (en) | 2006-01-27 | 2010-05-16 | Astrazeneca Ab | Novel heteroaryl substituted benzothiazoles |
| CA2641880C (en) * | 2006-02-10 | 2014-09-09 | Summit Corporation Plc | Treatment of duchenne muscular dystrophy |
| WO2008118122A2 (en) | 2006-05-08 | 2008-10-02 | Molecular Neuroimaging, Llc | Compounds and amyloid probes thereof for therapeutic and imaging uses |
| WO2008091195A1 (en) | 2007-01-22 | 2008-07-31 | Astrazeneca Ab | Novel heteroaryl substituted imidazo [1,2 -a] pyridine derivatives |
-
2007
- 2007-06-08 TW TW096120843A patent/TW200813035A/zh unknown
- 2007-06-14 US US11/763,151 patent/US7670591B2/en not_active Expired - Fee Related
- 2007-06-18 CA CA002655084A patent/CA2655084A1/en not_active Abandoned
- 2007-06-18 WO PCT/SE2007/000591 patent/WO2007149030A1/en not_active Ceased
- 2007-06-18 EP EP07748254A patent/EP2035418A1/en not_active Withdrawn
- 2007-06-18 CN CN2007800308078A patent/CN101506201B/zh not_active Expired - Fee Related
- 2007-06-18 MX MX2008015718A patent/MX2008015718A/es not_active Application Discontinuation
- 2007-06-18 AU AU2007261786A patent/AU2007261786A1/en not_active Abandoned
- 2007-06-18 KR KR1020097000992A patent/KR20090021224A/ko not_active Withdrawn
- 2007-06-18 UY UY30419A patent/UY30419A1/es not_active Application Discontinuation
- 2007-06-18 CL CL2007001784A patent/CL2007001784A1/es unknown
- 2007-06-18 JP JP2009516443A patent/JP5548842B2/ja not_active Expired - Fee Related
- 2007-06-19 AR ARP070102680A patent/AR061515A1/es unknown
-
2008
- 2008-11-28 ZA ZA200810163A patent/ZA200810163B/xx unknown
- 2008-12-02 IL IL195669A patent/IL195669A0/en unknown
-
2009
- 2009-01-13 NO NO20090201A patent/NO20090201L/no not_active Application Discontinuation
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