RU2158266C2 - Способ получения пуриновых соединений, используемое в нем промежуточное соединение и способ его получения - Google Patents

Способ получения пуриновых соединений, используемое в нем промежуточное соединение и способ его получения Download PDF

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Publication number
RU2158266C2
RU2158266C2 RU96121936/04A RU96121936A RU2158266C2 RU 2158266 C2 RU2158266 C2 RU 2158266C2 RU 96121936/04 A RU96121936/04 A RU 96121936/04A RU 96121936 A RU96121936 A RU 96121936A RU 2158266 C2 RU2158266 C2 RU 2158266C2
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RU
Russia
Prior art keywords
formula
compound
amino group
compounds
hydrogen
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RU96121936/04A
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English (en)
Russian (ru)
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RU96121936A (ru
Inventor
Джон Роберт Мэнсфилд Дэйлз
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СмитКлайн Бичем ПЛК
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Publication of RU2158266C2 publication Critical patent/RU2158266C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Chemical Treatment Of Metals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RU96121936/04A 1994-04-19 1995-04-19 Способ получения пуриновых соединений, используемое в нем промежуточное соединение и способ его получения RU2158266C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9407698.1 1994-04-19
GB9407698A GB9407698D0 (en) 1994-04-19 1994-04-19 Pharmaceuticals

Publications (2)

Publication Number Publication Date
RU96121936A RU96121936A (ru) 1999-01-27
RU2158266C2 true RU2158266C2 (ru) 2000-10-27

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Application Number Title Priority Date Filing Date
RU96121936/04A RU2158266C2 (ru) 1994-04-19 1995-04-19 Способ получения пуриновых соединений, используемое в нем промежуточное соединение и способ его получения

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Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9807114D0 (en) 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
GB9807116D0 (en) 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
US20040097528A1 (en) * 2002-08-26 2004-05-20 Ben-Zion Dolitzky Crystalline solid famciclovir forms I, II, III and preparation thereof
EP1511750A1 (en) * 2003-04-30 2005-03-09 Teva Pharmaceutical Industries Ltd. Process for the preparation of famciclovir
EP1556383A1 (en) * 2003-09-04 2005-07-27 Teva Pharmaceutical Industries Ltd. Process for preparing famciclovir
US7458839B2 (en) * 2006-02-21 2008-12-02 Fci Americas Technology, Inc. Electrical connectors having power contacts with alignment and/or restraining features
US20050215787A1 (en) * 2004-03-26 2005-09-29 Joshi Ramesh A An improved process for the preparation of purines
KR20070012540A (ko) 2004-05-18 2007-01-25 테바 파마슈티컬 인더스트리즈 리미티드 결정성 고체 팜시클로버의 제조를 위한 건조방법
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir
CN102070636B (zh) * 2011-01-17 2012-05-23 浙江大学 喷昔洛韦的制备方法
CN104086552B (zh) * 2014-07-31 2016-01-13 济南兆康医药科技有限公司 一种喷昔洛韦的精制方法
CN104496991A (zh) * 2014-11-04 2015-04-08 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3–羟甲基丁基)嘌呤的制备方法
CN104744472A (zh) * 2015-03-12 2015-07-01 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3-羟甲基丁基)嘌呤的制备方法
CN108314685B (zh) * 2018-03-16 2020-08-25 上药康丽（常州）药业有限公司 一种2-氨基-6-氯-9-(4-乙酰氧基-3-乙酰氧甲基丁基)嘌呤的制备方法
CN110713490A (zh) * 2018-07-12 2020-01-21 浙江医药股份有限公司新昌制药厂 一种喷昔洛韦的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1342421A3 (ru) * 1982-10-14 1987-09-30 Дзе Веллкам Фаундейшн Лимитед (Фирма) Способ получени производных пурина
EP0420559A2 (en) * 1989-09-28 1991-04-03 Beecham Group p.l.c. Process for the preparation of purine compounds
US5175268A (en) * 1986-12-24 1992-12-29 Takeda Chemical Industries, Ltd. DNA encoding recombinant human lymphotoxin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
EP0302644B1 (en) * 1987-08-01 1997-01-29 Beecham Group Plc Purine compounds and their preparation
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
GB8822236D0 (en) * 1988-09-21 1988-10-26 Beecham Group Plc Chemical process

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1342421A3 (ru) * 1982-10-14 1987-09-30 Дзе Веллкам Фаундейшн Лимитед (Фирма) Способ получени производных пурина
US5175268A (en) * 1986-12-24 1992-12-29 Takeda Chemical Industries, Ltd. DNA encoding recombinant human lymphotoxin
EP0420559A2 (en) * 1989-09-28 1991-04-03 Beecham Group p.l.c. Process for the preparation of purine compounds

Also Published As

Publication number Publication date
CZ305396A3 (en) 1997-06-11
KR970702280A (ko) 1997-05-13
TW311138B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1997-07-21
MY128846A (en) 2007-02-28
IL113409A0 (en) 1995-07-31
HUT75339A (en) 1997-05-28
NO315000B1 (no) 2003-06-23
NZ287858A (en) 1998-06-26
KR100327147B1 (ko) 2002-07-27
US6846927B1 (en) 2005-01-25
MA23518A1 (fr) 1995-12-31
RO118950B1 (ro) 2004-01-30
CZ287674B6 (en) 2001-01-17
WO1995028402A3 (en) 1996-01-25
ZA953110B (en) 1996-05-20
GB9407698D0 (en) 1994-06-15
PL181219B1 (pl) 2001-06-29
AP703A (en) 1998-12-04
IL113409A (en) 1999-08-17
DE69520945D1 (de) 2001-06-21
FI119691B (fi) 2009-02-13
ATE201209T1 (de) 2001-06-15
OA10376A (en) 2001-11-20
EP0756597A1 (en) 1997-02-05
BG63464B1 (bg) 2002-02-28
AU691000B2 (en) 1998-05-07
CA2188181A1 (en) 1995-10-26
PT756597E (pt) 2001-11-30
DE69520945T2 (de) 2002-03-28
DK0756597T3 (da) 2001-08-20
CN1045963C (zh) 1999-10-27
SK133296A3 (en) 1997-05-07
WO1995028402A2 (en) 1995-10-26
HU226209B1 (en) 2008-06-30
SA95150619B1 (ar) 2005-05-04
EG20938A (en) 2000-06-28
JP3936734B2 (ja) 2007-06-27
AP582A (en) 1997-04-09
FI964193A0 (fi) 1996-10-18
MX9604942A (es) 1998-05-31
EP0756597B1 (en) 2001-05-16
HU9602891D0 (en) 1996-12-30
US7355043B2 (en) 2008-04-08
US20050101570A1 (en) 2005-05-12
SK283193B6 (sk) 2003-03-04
CA2188181C (en) 2007-04-17
HK1012348A1 (en) 1999-07-30
GR3036338T3 (en) 2001-11-30
AP9600870A0 (en) 1996-10-31
UA47401C2 (uk) 2002-07-15
DZ1872A1 (fr) 2002-02-17
NO964395L (no) 1996-10-15
IN183830B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2000-04-29
FI964193A7 (fi) 1996-12-18
BR9507494A (pt) 1997-08-12
BG100926A (en) 1997-07-31
CN1150427A (zh) 1997-05-21
NO964395D0 (no) 1996-10-15
JPH09512000A (ja) 1997-12-02
AU2670695A (en) 1995-11-10
AP9500730A0 (en) 1995-04-30
PL316943A1 (en) 1997-02-17
ES2158948T3 (es) 2001-09-16

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