PT966485E - Domínios de igg2 mutados não activantes e anticorpos anti-cd3 incorporando os mesmos - Google Patents

Domínios de igg2 mutados não activantes e anticorpos anti-cd3 incorporando os mesmos Download PDF

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Publication number
PT966485E
PT966485E PT97927677T PT97927677T PT966485E PT 966485 E PT966485 E PT 966485E PT 97927677 T PT97927677 T PT 97927677T PT 97927677 T PT97927677 T PT 97927677T PT 966485 E PT966485 E PT 966485E
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PT
Portugal
Prior art keywords
antibodies
same
mutated
nonactivating
antibodies incorporating
Prior art date
Application number
PT97927677T
Other languages
English (en)
Inventor
J Yun Tso
Michael S Cole
Claudio Anasetti
Original Assignee
Pdl Biopharma Inc
Hutchinson Fred Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pdl Biopharma Inc, Hutchinson Fred Cancer Res filed Critical Pdl Biopharma Inc
Publication of PT966485E publication Critical patent/PT966485E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT97927677T 1996-05-20 1997-05-19 Domínios de igg2 mutados não activantes e anticorpos anti-cd3 incorporando os mesmos PT966485E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65041096A 1996-05-20 1996-05-20
US08/656,586 US5834597A (en) 1996-05-20 1996-05-31 Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same

Publications (1)

Publication Number Publication Date
PT966485E true PT966485E (pt) 2008-12-10

Family

ID=27095860

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97927677T PT966485E (pt) 1996-05-20 1997-05-19 Domínios de igg2 mutados não activantes e anticorpos anti-cd3 incorporando os mesmos

Country Status (11)

Country Link
US (1) US5834597A (pt)
EP (1) EP0966485B1 (pt)
JP (2) JP3947570B2 (pt)
CN (1) CN100549031C (pt)
AT (1) ATE407952T1 (pt)
AU (1) AU725821B2 (pt)
CA (1) CA2255826C (pt)
DE (1) DE69738984D1 (pt)
ES (1) ES2313736T3 (pt)
PT (1) PT966485E (pt)
WO (1) WO1997044362A1 (pt)

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