PL368286A1 - Naphtyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (pde4) inhibitors - Google Patents

Naphtyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (pde4) inhibitors

Info

Publication number
PL368286A1
PL368286A1 PL02368286A PL36828602A PL368286A1 PL 368286 A1 PL368286 A1 PL 368286A1 PL 02368286 A PL02368286 A PL 02368286A PL 36828602 A PL36828602 A PL 36828602A PL 368286 A1 PL368286 A1 PL 368286A1
Authority
PL
Poland
Prior art keywords
pde4
inhibitors
preparation
phosphodiesterase isoenzyme
naphtyridine
Prior art date
Application number
PL02368286A
Other languages
English (en)
Polish (pl)
Inventor
Alastair Denholm
Thomas Hugo Keller
Clive Mccarthy
Neil John Press
Roger John Taylor
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0126511A external-priority patent/GB0126511D0/en
Priority claimed from GB0209882A external-priority patent/GB0209882D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL368286A1 publication Critical patent/PL368286A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
PL02368286A 2001-11-05 2002-11-04 Naphtyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (pde4) inhibitors PL368286A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0126511A GB0126511D0 (en) 2001-11-05 2001-11-05 Organic compounds
GB0209882A GB0209882D0 (en) 2002-04-30 2002-04-30 Organic compounds

Publications (1)

Publication Number Publication Date
PL368286A1 true PL368286A1 (en) 2005-03-21

Family

ID=26246741

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02368286A PL368286A1 (en) 2001-11-05 2002-11-04 Naphtyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (pde4) inhibitors

Country Status (25)

Country Link
US (1) US7273875B2 (OSRAM)
EP (1) EP1443925B8 (OSRAM)
JP (1) JP4150672B2 (OSRAM)
KR (1) KR100623548B1 (OSRAM)
CN (1) CN1298324C (OSRAM)
AR (1) AR037517A1 (OSRAM)
AT (1) ATE349209T1 (OSRAM)
BR (1) BR0213877A (OSRAM)
CA (1) CA2462211C (OSRAM)
CY (1) CY1107532T1 (OSRAM)
DE (1) DE60217160T2 (OSRAM)
DK (1) DK1443925T3 (OSRAM)
ES (1) ES2275935T3 (OSRAM)
HU (1) HUP0402311A3 (OSRAM)
IL (2) IL161257A0 (OSRAM)
MX (1) MXPA04004264A (OSRAM)
MY (1) MY130622A (OSRAM)
NO (1) NO329093B1 (OSRAM)
NZ (1) NZ532586A (OSRAM)
PE (1) PE20030535A1 (OSRAM)
PL (1) PL368286A1 (OSRAM)
PT (1) PT1443925E (OSRAM)
RU (1) RU2296764C2 (OSRAM)
TW (1) TWI320784B (OSRAM)
WO (1) WO2003039544A1 (OSRAM)

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GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
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JP5781510B2 (ja) 2009-08-12 2015-09-24 ノバルティス アーゲー ヘテロ環式ヒドラゾン化合物および癌および炎症の処置のためのそれらの使用
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KR20120089463A (ko) 2009-08-20 2012-08-10 노파르티스 아게 헤테로시클릭 옥심 화합물
KR20120091037A (ko) * 2009-10-01 2012-08-17 알콘 리서치, 리미티드 올로파타딘 조성물 및 그의 용도
MX2012004792A (es) 2009-10-22 2013-02-01 Vertex Pharma Composiciones para el tratamiento de fibrosis quistica y otras enfermedades cronicas.
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US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
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BR112016024484A2 (pt) 2014-04-24 2017-08-15 Novartis Ag derivados de aminopiridina como inibidores de fosfatidilinositol 3-quinase
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