AU2002317910A1 - Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof - Google Patents
Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereofInfo
- Publication number
- AU2002317910A1 AU2002317910A1 AU2002317910A AU2002317910A AU2002317910A1 AU 2002317910 A1 AU2002317910 A1 AU 2002317910A1 AU 2002317910 A AU2002317910 A AU 2002317910A AU 2002317910 A AU2002317910 A AU 2002317910A AU 2002317910 A1 AU2002317910 A1 AU 2002317910A1
- Authority
- AU
- Australia
- Prior art keywords
- preparation
- cyclic nucleotide
- phosphodiesterase inhibitors
- nucleotide phosphodiesterase
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940082638 cardiac stimulant Phosphodiesterase inhibitors Drugs 0.000 title 1
- 125000004122 cyclic group Chemical group 0.000 title 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 title 1
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2008221554A AU2008221554A1 (en) | 2001-06-07 | 2008-09-18 | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR01/07458 | 2001-06-07 | ||
FR0107458 | 2001-06-07 | ||
PCT/FR2002/001952 WO2002098865A2 (en) | 2001-06-07 | 2002-06-07 | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2008221554A Division AU2008221554A1 (en) | 2001-06-07 | 2008-09-18 | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2002317910A1 true AU2002317910A1 (en) | 2003-05-08 |
AU2002317910B2 AU2002317910B2 (en) | 2008-06-19 |
Family
ID=8864056
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002317910A Ceased AU2002317910B2 (en) | 2001-06-07 | 2002-06-07 | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof |
AU2008221554A Abandoned AU2008221554A1 (en) | 2001-06-07 | 2008-09-18 | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2008221554A Abandoned AU2008221554A1 (en) | 2001-06-07 | 2008-09-18 | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof |
Country Status (9)
Country | Link |
---|---|
US (1) | US7250410B2 (en) |
EP (1) | EP1392663A2 (en) |
JP (1) | JP2005503356A (en) |
AU (2) | AU2002317910B2 (en) |
CA (1) | CA2446696A1 (en) |
IL (2) | IL159105A0 (en) |
NZ (1) | NZ529582A (en) |
WO (1) | WO2002098865A2 (en) |
ZA (1) | ZA200400057B (en) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7572788B2 (en) * | 1999-04-30 | 2009-08-11 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US20030119029A1 (en) * | 1999-04-30 | 2003-06-26 | Regents Of The University Of Michigan | Compositions and methods relating to novel benzodiazepine compounds and targets thereof |
US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US20060025388A1 (en) * | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
DE60007960T2 (en) | 1999-04-30 | 2004-10-21 | Univ Michigan Ann Arbor | Therapeutic applications of pro-apoptotic benzodiazepines |
CN1703395A (en) * | 2002-08-09 | 2005-11-30 | 特兰斯泰克制药公司 | Aryl and heteroaryl compounds and methods to modulate coagulation |
AU2003288352A1 (en) * | 2002-10-30 | 2004-06-07 | Centre National De La Recherche Scientifique (Cnrs) | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses |
FR2846653B1 (en) * | 2002-10-30 | 2007-04-20 | Neuro3D | INHIBITORS OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, PREPARATION AND USES |
US7459472B2 (en) * | 2003-08-08 | 2008-12-02 | Transtech Pharma, Inc. | Aryl and heteroaryl compounds, compositions, and methods of use |
US7208601B2 (en) * | 2003-08-08 | 2007-04-24 | Mjalli Adnan M M | Aryl and heteroaryl compounds, compositions, and methods of use |
EP1548011A1 (en) * | 2003-12-23 | 2005-06-29 | Neuro3D | Benzo[1,4]diazepin-2-one derivatives as phosphodiesterase PDE2 inhibitors, preparation and therapeutic use thereof |
US20090275099A1 (en) * | 2004-04-27 | 2009-11-05 | Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
US20050272723A1 (en) * | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
FR2870539B1 (en) * | 2004-05-19 | 2006-08-04 | Greenpharma Sa Sa | NEW METHODS AND MEDICINES |
EP1784390A2 (en) | 2004-08-13 | 2007-05-16 | Amgen Inc. | Substituted benzofused heterocycles |
US20060052369A1 (en) * | 2004-09-07 | 2006-03-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
EP1893218A4 (en) * | 2005-06-01 | 2011-01-12 | Univ Michigan | Unsolvated benzodiazepine compositions and methods |
US20070105844A1 (en) * | 2005-10-26 | 2007-05-10 | Regents Of The University Of Michigan | Therapeutic compositions and methods |
EP1948191B1 (en) * | 2005-11-01 | 2013-01-16 | The Regents of the University of Michigan | Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties |
US7759338B2 (en) * | 2006-04-27 | 2010-07-20 | The Regents Of The University Of Michigan | Soluble 1,4 benzodiazepine compounds and stable salts thereof |
EP2037741B1 (en) | 2006-06-09 | 2013-11-27 | The Regents Of The University Of Michigan | Benzodiazepine derivatives for use in the treatment of immune, inflammatory and proliferative disorders |
CA2680017C (en) | 2007-03-09 | 2013-11-12 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
CA2685860A1 (en) * | 2007-05-10 | 2008-11-20 | Amr Technology, Inc. | Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
CA2698248C (en) * | 2007-09-14 | 2017-08-29 | The Regents Of The University Of Michigan | Phenyl acyl guanidine derivatives as f1f0-atpase inhibitors and the use thereof |
WO2009037302A1 (en) * | 2007-09-18 | 2009-03-26 | Via Pharmaceuticals, Inc. | 5-substituted-1, 4-benz0diazepines as phosphodiesterase inhibitors |
CA2703005A1 (en) | 2007-11-06 | 2009-05-14 | The Regents Of The University Of Michigan | Benzodiazepinone compounds useful in the treatment of skin conditions |
US8497307B2 (en) | 2008-09-11 | 2013-07-30 | The Regents Of The University Of Michigan | Aryl guanidine F1F0-ATPase inhibitors and related methods |
US8604023B2 (en) | 2009-04-17 | 2013-12-10 | The Regents Of The University Of Michigan | 1,4-benzodiazepinone compounds and their use in treating cancer |
EP2470020A4 (en) | 2009-09-18 | 2013-03-13 | Univ Michigan | Benzodiazepinone compounds and methods of treatment using same |
CA2780333C (en) | 2009-11-17 | 2016-05-24 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
AU2010322287B2 (en) | 2009-11-17 | 2014-04-03 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
US9249161B2 (en) | 2010-12-02 | 2016-02-02 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
AR084070A1 (en) | 2010-12-02 | 2013-04-17 | Constellation Pharmaceuticals Inc | BROMODOMINIUM INHIBITORS AND USES OF THE SAME |
US9422292B2 (en) | 2011-05-04 | 2016-08-23 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
EP2721031B1 (en) | 2011-06-17 | 2016-01-20 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
EP2864336B1 (en) | 2012-06-06 | 2016-11-23 | Constellation Pharmaceuticals, Inc. | Benzo[b]isoxazoloazepine bromodomain inhibitors and uses thereof |
TWI602820B (en) | 2012-06-06 | 2017-10-21 | 星宿藥物公司 | Bromodomain inhibitors and uses thereof |
CA2952830C (en) | 2014-06-20 | 2022-11-01 | Constellation Pharmaceuticals, Inc. | Crystalline forms of 2-((4s)-6-(4-chlorophenyl)-1-methyl-4h-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide |
WO2023220395A1 (en) * | 2022-05-13 | 2023-11-16 | University Of Cincinnati | Benzodiazepine analogs and methods of use in treating cancer |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH414652A (en) | 1959-12-10 | 1966-06-15 | Hoffmann La Roche | Process for the preparation of 1,4-benzodiazepine derivatives |
NL279830A (en) | 1961-06-20 | |||
US3182067A (en) | 1964-04-09 | 1965-05-04 | Hoffmann La Roche | Benzodiazepine compounds |
FR1497456A (en) | 1964-06-15 | 1967-10-13 | Clin Byla Ets | Ortho-amino aryl ketimines, heterocyclic compounds attached to them and preparation of these various bodies |
IL29988A0 (en) | 1967-06-23 | 1968-07-25 | American Cyanamid Co | Novel 7-trifluoromethoxybenzo-1,4-diazepines |
US3631029A (en) | 1967-12-01 | 1971-12-28 | Sumitomo Chemical Co | Process for producing benzodiazepine derivatives |
FR2085645A1 (en) | 1970-04-22 | 1971-12-31 | Chimidrog | 1-phenyl-2,3-benzodiazepin-4-ones - as tranquillizers |
US3801569A (en) | 1973-01-15 | 1974-04-02 | Hoffmann La Roche | 7-(1,1-difluoroalkyl)-1,4-benzodiazepines |
DE3119874A1 (en) | 1981-05-19 | 1982-12-09 | Dr. Karl Thomae Gmbh, 7950 Biberach | "BENZAZEPINE DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS" |
PH26955A (en) | 1989-03-08 | 1992-12-03 | Kali Chemie Pharma Gmbh | Novel 1,7-fused 1H-indole-2-carboxylic acid N-(1,4-benzodiazepin-3-YL) amides |
TW221687B (en) | 1992-01-24 | 1994-03-11 | Hoffmann La Roche | |
DE19604920A1 (en) * | 1996-02-01 | 1997-08-07 | Schering Ag | New 2,3-benzodiazepine derivatives, their production and use as medicines |
US5891871A (en) | 1996-03-21 | 1999-04-06 | Cocensys, Inc. | Substituted 2,3-benzodiazepin-4-ones and the use thereof |
AU4565600A (en) | 1999-06-18 | 2001-01-09 | Synt:Em (S.A.) | Identifying active molecules using physico-chemical parameters |
WO2002051232A2 (en) | 2000-12-27 | 2002-07-04 | Actelion Pharmaceuticals Ltd. | Novel benzazepines and related heterocyclic derivatives |
-
2002
- 2002-06-07 WO PCT/FR2002/001952 patent/WO2002098865A2/en active Application Filing
- 2002-06-07 NZ NZ529582A patent/NZ529582A/en unknown
- 2002-06-07 AU AU2002317910A patent/AU2002317910B2/en not_active Ceased
- 2002-06-07 IL IL15910502A patent/IL159105A0/en unknown
- 2002-06-07 EP EP02747514A patent/EP1392663A2/en not_active Withdrawn
- 2002-06-07 JP JP2003501989A patent/JP2005503356A/en active Pending
- 2002-06-07 US US10/479,000 patent/US7250410B2/en not_active Expired - Fee Related
- 2002-06-07 CA CA002446696A patent/CA2446696A1/en not_active Abandoned
-
2003
- 2003-11-27 IL IL159105A patent/IL159105A/en not_active IP Right Cessation
-
2004
- 2004-01-06 ZA ZA200400057A patent/ZA200400057B/en unknown
-
2008
- 2008-09-18 AU AU2008221554A patent/AU2008221554A1/en not_active Abandoned
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