PL2217572T3 - Modulatory izochinolinowe transporterów zawierających kasetę wiążącą ATP - Google Patents

Modulatory izochinolinowe transporterów zawierających kasetę wiążącą ATP

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Publication number
PL2217572T3
PL2217572T3 PL08849242T PL08849242T PL2217572T3 PL 2217572 T3 PL2217572 T3 PL 2217572T3 PL 08849242 T PL08849242 T PL 08849242T PL 08849242 T PL08849242 T PL 08849242T PL 2217572 T3 PL2217572 T3 PL 2217572T3
Authority
PL
Poland
Prior art keywords
isoquinoline
atp
modulators
binding cassette
cassette transporters
Prior art date
Application number
PL08849242T
Other languages
English (en)
Polish (pl)
Inventor
Ruah Sara Hadida
Mark Miller
Jinglan Zhou
Brian Bear
Peter D J Grootenhuis
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of PL2217572T3 publication Critical patent/PL2217572T3/pl

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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PL08849242T 2007-11-16 2008-11-14 Modulatory izochinolinowe transporterów zawierających kasetę wiążącą ATP PL2217572T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98855907P 2007-11-16 2007-11-16
PCT/US2008/083517 WO2009064959A1 (en) 2007-11-16 2008-11-14 Isoquinoline modulators of atp-binding cassette transporters
EP20080849242 EP2217572B1 (en) 2007-11-16 2008-11-14 Isoquinoline modulators of atp-binding cassette transporters

Publications (1)

Publication Number Publication Date
PL2217572T3 true PL2217572T3 (pl) 2014-04-30

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
PL08849242T PL2217572T3 (pl) 2007-11-16 2008-11-14 Modulatory izochinolinowe transporterów zawierających kasetę wiążącą ATP
PL12181370T PL2578571T3 (pl) 2007-11-16 2008-11-14 Modulatory izochinolinowe transporterów zawierających kasetę wiążącą ATP

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL12181370T PL2578571T3 (pl) 2007-11-16 2008-11-14 Modulatory izochinolinowe transporterów zawierających kasetę wiążącą ATP

Country Status (16)

Country Link
US (4) US8507524B2 (https=)
EP (3) EP2578571B1 (https=)
JP (3) JP5646338B2 (https=)
CN (2) CN101952254B (https=)
AU (1) AU2008322616B2 (https=)
CA (1) CA2705562C (https=)
CY (1) CY1115318T1 (https=)
DK (2) DK2217572T3 (https=)
ES (3) ES2658064T3 (https=)
HR (2) HRP20140103T1 (https=)
HU (1) HUE026334T2 (https=)
NZ (2) NZ585980A (https=)
PL (2) PL2217572T3 (https=)
PT (2) PT2578571E (https=)
SI (2) SI2578571T1 (https=)
WO (1) WO2009064959A1 (https=)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2006111093A (ru) 2003-09-06 2007-10-27 Вертекс Фармасьютикалз Инкорпорейтед (Us) Модуляторы атр-связывающих кассетных транспортеров
CN101675928A (zh) * 2003-11-14 2010-03-24 沃泰克斯药物股份有限公司 可用作atp-结合弹夹转运蛋白调控剂的噻唑和噁唑
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