JP5646338B2 - Atp結合カセットトランスポーターのイソキノリン調節因子 - Google Patents

Atp結合カセットトランスポーターのイソキノリン調節因子 Download PDF

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JP5646338B2
JP5646338B2 JP2010534201A JP2010534201A JP5646338B2 JP 5646338 B2 JP5646338 B2 JP 5646338B2 JP 2010534201 A JP2010534201 A JP 2010534201A JP 2010534201 A JP2010534201 A JP 2010534201A JP 5646338 B2 JP5646338 B2 JP 5646338B2
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optionally substituted
aliphatic
heteroaryl
aryl
cftr
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JP2011505338A (ja
JP2011505338A5 (https=
Inventor
ルーアー, サラ ハディダ
ルーアー, サラ ハディダ
マーク ミラー,
マーク ミラー,
チンラン チョウ,
チンラン チョウ,
ブライアン ベアー,
ブライアン ベアー,
ぺーター デー. イェー. グルーテンヒュイス,
ぺーター デー. イェー. グルーテンヒュイス,
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
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    • C07ORGANIC CHEMISTRY
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JP2010534201A 2007-11-16 2008-11-14 Atp結合カセットトランスポーターのイソキノリン調節因子 Active JP5646338B2 (ja)

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US98855907P 2007-11-16 2007-11-16
US60/988,559 2007-11-16
PCT/US2008/083517 WO2009064959A1 (en) 2007-11-16 2008-11-14 Isoquinoline modulators of atp-binding cassette transporters

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JP2014018471A Division JP5885359B2 (ja) 2007-11-16 2014-02-03 Atp結合カセットトランスポーターのイソキノリン調節因子

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JP2011505338A JP2011505338A (ja) 2011-02-24
JP2011505338A5 JP2011505338A5 (https=) 2012-12-06
JP5646338B2 true JP5646338B2 (ja) 2014-12-24

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JP2010534201A Active JP5646338B2 (ja) 2007-11-16 2008-11-14 Atp結合カセットトランスポーターのイソキノリン調節因子
JP2014018471A Active JP5885359B2 (ja) 2007-11-16 2014-02-03 Atp結合カセットトランスポーターのイソキノリン調節因子
JP2015159316A Pending JP2015205936A (ja) 2007-11-16 2015-08-12 Atp結合カセットトランスポーターのイソキノリン調節因子

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JP2015159316A Pending JP2015205936A (ja) 2007-11-16 2015-08-12 Atp結合カセットトランスポーターのイソキノリン調節因子

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US (4) US8507524B2 (https=)
EP (3) EP2578571B1 (https=)
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CN (2) CN102743385B (https=)
AU (1) AU2008322616B2 (https=)
CA (1) CA2705562C (https=)
CY (1) CY1115318T1 (https=)
DK (2) DK2217572T3 (https=)
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HR (2) HRP20140103T1 (https=)
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NZ (2) NZ598941A (https=)
PL (2) PL2578571T3 (https=)
PT (2) PT2217572E (https=)
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