PL1622569T3 - Pochodne aza spiro alkanów jako inhibitory metaloproteaz - Google Patents
Pochodne aza spiro alkanów jako inhibitory metaloproteazInfo
- Publication number
- PL1622569T3 PL1622569T3 PL04760368T PL04760368T PL1622569T3 PL 1622569 T3 PL1622569 T3 PL 1622569T3 PL 04760368 T PL04760368 T PL 04760368T PL 04760368 T PL04760368 T PL 04760368T PL 1622569 T3 PL1622569 T3 PL 1622569T3
- Authority
- PL
- Poland
- Prior art keywords
- metallproteases
- inhibitors
- alkane derivatives
- aza spiro
- spiro alkane
- Prior art date
Links
- -1 Aza spiro alkane Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
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- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/10—Spiro-condensed systems
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EP04760368.3A EP1622569B1 (en) | 2003-04-24 | 2004-04-23 | Aza spiro alkane derivatives as inhibitors of metallproteases |
PCT/US2004/012672 WO2004096139A2 (en) | 2003-04-24 | 2004-04-23 | Aza spiro alkane derivatives as inhibitors of metalloproteases |
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PL04760368T PL1622569T3 (pl) | 2003-04-24 | 2004-04-23 | Pochodne aza spiro alkanów jako inhibitory metaloproteaz |
PL380275A PL217630B1 (pl) | 2003-04-24 | 2004-04-23 | Pochodne azaspiroalkanów, kompozycja farmaceutyczna oraz zastosowanie związku |
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