IT1304888B1 - Composti monociclici ad azione nk-2 antagonista e formulazioni che licontengono - Google Patents

Composti monociclici ad azione nk-2 antagonista e formulazioni che licontengono

Info

Publication number
IT1304888B1
IT1304888B1 IT1998FI000186A ITFI980186A IT1304888B1 IT 1304888 B1 IT1304888 B1 IT 1304888B1 IT 1998FI000186 A IT1998FI000186 A IT 1998FI000186A IT FI980186 A ITFI980186 A IT FI980186A IT 1304888 B1 IT1304888 B1 IT 1304888B1
Authority
IT
Italy
Prior art keywords
monocyclic
antagonist
formulations
contain
action compounds
Prior art date
Application number
IT1998FI000186A
Other languages
English (en)
Inventor
Antonio Guidi
Maria Altamura
Carlo Alberto Maggi
Enzo Perrotta
Marco Criscuoli
Original Assignee
Menarini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche Spa filed Critical Menarini Ricerche Spa
Priority to IT1998FI000186A priority Critical patent/IT1304888B1/it
Priority to TW088112671A priority patent/TW491857B/zh
Priority to EP99941479A priority patent/EP1102789A1/en
Priority to JP2000563679A priority patent/JP2002522450A/ja
Priority to TR2001/00354T priority patent/TR200100354T2/xx
Priority to PCT/EP1999/005459 priority patent/WO2000008046A1/en
Priority to CA002339638A priority patent/CA2339638A1/en
Priority to AU55079/99A priority patent/AU5507999A/en
Priority to PE1999000784A priority patent/PE20001002A1/es
Priority to ARP990103922A priority patent/AR021751A1/es
Priority to CO99049466A priority patent/CO5080789A1/es
Publication of ITFI980186A1 publication Critical patent/ITFI980186A1/it
Application granted granted Critical
Publication of IT1304888B1 publication Critical patent/IT1304888B1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/22Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IT1998FI000186A 1998-08-05 1998-08-05 Composti monociclici ad azione nk-2 antagonista e formulazioni che licontengono IT1304888B1 (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT1998FI000186A IT1304888B1 (it) 1998-08-05 1998-08-05 Composti monociclici ad azione nk-2 antagonista e formulazioni che licontengono
TW088112671A TW491857B (en) 1998-08-05 1999-07-27 Monocyclic compounds having NK-2 antagonist action and compositions containing them
JP2000563679A JP2002522450A (ja) 1998-08-05 1999-07-30 Nk−2拮抗作用を有する単環式化合物及びそれらを含有した組成物
TR2001/00354T TR200100354T2 (tr) 1998-08-05 1999-07-30 NK-2 Antagonist hareketine sahip monosiklik bileşimler ve oluşumlar.
EP99941479A EP1102789A1 (en) 1998-08-05 1999-07-30 Monocyclic compounds having nk-2 antagonist action and compositions containing them
PCT/EP1999/005459 WO2000008046A1 (en) 1998-08-05 1999-07-30 Monocyclic compounds having nk-2 antagonist action and compositions containing them
CA002339638A CA2339638A1 (en) 1998-08-05 1999-07-30 Monocyclic compounds having nk-2 antagonist action and compositions containing them
AU55079/99A AU5507999A (en) 1998-08-05 1999-07-30 Monocyclic compounds having nk-2 antagonist action and compositions containing them
PE1999000784A PE20001002A1 (es) 1998-08-05 1999-08-04 Compuestos monociclicos con accion antagonista nk2 y composicion que los contiene
ARP990103922A AR021751A1 (es) 1998-08-05 1999-08-05 Compuestos monociclicos, composiciones farmaceuticas que los contienen y su uso como antagonistas de receptor nk2 de taquiquinina en el tratamiento depatologias donde hay liberacion de taquiquininas
CO99049466A CO5080789A1 (es) 1998-08-05 1999-08-05 Compuestos monociclicos con accion antagonista nk2 y composicion que los contiene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998FI000186A IT1304888B1 (it) 1998-08-05 1998-08-05 Composti monociclici ad azione nk-2 antagonista e formulazioni che licontengono

Publications (2)

Publication Number Publication Date
ITFI980186A1 ITFI980186A1 (it) 2000-02-05
IT1304888B1 true IT1304888B1 (it) 2001-04-05

Family

ID=11352646

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998FI000186A IT1304888B1 (it) 1998-08-05 1998-08-05 Composti monociclici ad azione nk-2 antagonista e formulazioni che licontengono

Country Status (11)

Country Link
EP (1) EP1102789A1 (it)
JP (1) JP2002522450A (it)
AR (1) AR021751A1 (it)
AU (1) AU5507999A (it)
CA (1) CA2339638A1 (it)
CO (1) CO5080789A1 (it)
IT (1) IT1304888B1 (it)
PE (1) PE20001002A1 (it)
TR (1) TR200100354T2 (it)
TW (1) TW491857B (it)
WO (1) WO2000008046A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1307809B1 (it) 1999-10-21 2001-11-19 Menarini Ricerche Spa Composti monociclici basici ad azione nk-2 antagonista, processi difabbricazione e formulazioni che li contengono.
ES2563304T3 (es) 2003-04-24 2016-03-14 Incyte Holdings Corporation Derivados azaespiro alcano como inhibidores de metaloproteasas
UY38485A (es) 2018-11-27 2020-06-30 Novartis Ag Compuestos tetrámeros cíclicos como inhibidores de proproteína convertasa subtilisina/kexina tipo 9 (pcsk9), método de tratamiento, uso y su preparación

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703034A (en) * 1986-04-28 1987-10-27 Merck & Co., Inc. Novel cyclic tetrapeptide
AU2387592A (en) * 1991-08-08 1993-03-02 A. Menarini Industrie Farmaceutiche Riunite S.R.L. Cyclic hexapeptides as tachyquinin antagonists, their preparation and pharmaceutical compositions thereof
ES2103857T3 (es) * 1991-08-13 1997-10-01 Takeda Chemical Industries Ltd Peptidos ciclicos y su uso.
IT1277835B1 (it) * 1995-03-13 1997-11-12 Menarini Farma Ind Composti biciclici, loro preparazione ed uso in composizioni farmaceutiche
IT1291776B1 (it) * 1997-02-07 1999-01-21 Menarini Ricerche Spa Composti monociclici a quattro residui bifunzionali, aventi azione nk-2 antagonista

Also Published As

Publication number Publication date
AR021751A1 (es) 2002-08-07
TW491857B (en) 2002-06-21
CO5080789A1 (es) 2001-09-25
JP2002522450A (ja) 2002-07-23
ITFI980186A1 (it) 2000-02-05
TR200100354T2 (tr) 2001-05-21
EP1102789A1 (en) 2001-05-30
AU5507999A (en) 2000-02-28
CA2339638A1 (en) 2000-02-17
WO2000008046A1 (en) 2000-02-17
PE20001002A1 (es) 2000-10-16

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