CN103254290B - 基质金属蛋白酶-2多肽抑制剂及其应用 - Google Patents
基质金属蛋白酶-2多肽抑制剂及其应用 Download PDFInfo
- Publication number
- CN103254290B CN103254290B CN201310209065.2A CN201310209065A CN103254290B CN 103254290 B CN103254290 B CN 103254290B CN 201310209065 A CN201310209065 A CN 201310209065A CN 103254290 B CN103254290 B CN 103254290B
- Authority
- CN
- China
- Prior art keywords
- mmp
- matrix metal
- polypeptide
- metal proteinase
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310209065.2A CN103254290B (zh) | 2013-05-30 | 2013-05-30 | 基质金属蛋白酶-2多肽抑制剂及其应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310209065.2A CN103254290B (zh) | 2013-05-30 | 2013-05-30 | 基质金属蛋白酶-2多肽抑制剂及其应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103254290A CN103254290A (zh) | 2013-08-21 |
CN103254290B true CN103254290B (zh) | 2014-09-03 |
Family
ID=48958543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310209065.2A Active CN103254290B (zh) | 2013-05-30 | 2013-05-30 | 基质金属蛋白酶-2多肽抑制剂及其应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN103254290B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105601719A (zh) * | 2016-01-30 | 2016-05-25 | 苏州普罗达生物科技有限公司 | 拟组织金属蛋白酶抑制因子多肽及其应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL217630B1 (pl) * | 2003-04-24 | 2014-08-29 | Incyte Corp | Pochodne azaspiroalkanów, kompozycja farmaceutyczna oraz zastosowanie związku |
EP2598493A1 (en) * | 2010-07-30 | 2013-06-05 | Ranbaxy Laboratories Limited | Matrix metalloproteinase inhibitors |
-
2013
- 2013-05-30 CN CN201310209065.2A patent/CN103254290B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN103254290A (zh) | 2013-08-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103304634B (zh) | 基质金属蛋白酶-2多肽抑制剂及其应用 | |
Henikoff et al. | Assembly of variant histones into chromatin | |
EP1578988B1 (en) | Protein based tnf-alpha variants for the treatment of tnf-alpha related disorders | |
Goldberg | Hemoglobin degradation | |
Monda et al. | Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes | |
Dhanaraj et al. | X-ray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily | |
Merlet et al. | Regulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization | |
CN102268069B (zh) | 基质金属蛋白酶-9多肽抑制剂4及其应用 | |
US20070207961A1 (en) | TNF-alpha VARIANTS PROTEINS FOR THE TREATMENT OF TNF-alpha RELATED DISORDERS | |
US7687461B2 (en) | Treatment of TNF-α related disorders with TNF-α variant proteins | |
Stewart | Bradykinin antagonists: discovery and development | |
CN102268068B (zh) | 基质金属蛋白酶-9多肽抑制剂1及其应用 | |
Gu et al. | Evolutionary dynamics and molecular mechanisms of HORMA domain protein signaling | |
Dókus et al. | Modulators of calpain activity: Inhibitors and activators as potential drugs | |
CN102268070B (zh) | 基质金属蛋白酶-9多肽抑制剂2及其应用 | |
CN103254290B (zh) | 基质金属蛋白酶-2多肽抑制剂及其应用 | |
Vane | The history of inhibitors of angiotensin converting enzyme | |
Kuriyama et al. | A cell‐permeable NFAT inhibitor peptide prevents pressure‐overload cardiac hypertrophy | |
CN103275185B (zh) | 基质金属蛋白酶-2多肽抑制剂及其应用 | |
CN103275184B (zh) | 基质金属蛋白酶-2多肽抑制剂及其应用 | |
CN102250212B (zh) | 基质金属蛋白酶-9多肽抑制剂5及其应用 | |
CN102250213B (zh) | 基质金属蛋白酶-9多肽抑制剂3及其应用 | |
WO1993018794A1 (en) | In vivo peptide therapy | |
CN104387474B (zh) | 一种肿瘤血管梗塞剂多肽、基因、表达载体及其应用 | |
CN108484729B (zh) | 一种基质金属蛋白酶9的多肽抑制剂及其应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: NANTONG GUANGTAI BIOCHEMISTRY PRODUCT CO., LTD. Free format text: FORMER OWNER: SUZHOU PULUODA BIOLOG SCIENCE + TECHNOLOGY CO., LTD. Effective date: 20140805 |
|
C41 | Transfer of patent application or patent right or utility model | ||
C53 | Correction of patent for invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Li Chuntao Inventor before: Luo Ruixue |
|
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 215000 SUZHOU, JIANGSU PROVINCE TO: 226600 NANTONG, JIANGSU PROVINCE Free format text: CORRECT: INVENTOR; FROM: LUO RUIXUE TO: LI CHUNTAO |
|
TA01 | Transfer of patent application right |
Effective date of registration: 20140805 Address after: 226600, No. 188, chemical Avenue, fine chemical industrial park, Haian hi tech Zone, Nantong, Jiangsu Applicant after: Nantong Guangtai Biochemical Product Co., Ltd. Address before: High tech Zone Suzhou city Jiangsu province 215000 Chuk Yuen Road No. 209 Applicant before: Suzhou Pu Luo Da Biotechnology Co., Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant |