HUP0501182A3 - Aza spiro alkane derivatives as inhibitors of metallproteases and pharmaceutical compositions containing them - Google Patents
Aza spiro alkane derivatives as inhibitors of metallproteases and pharmaceutical compositions containing themInfo
- Publication number
- HUP0501182A3 HUP0501182A3 HU0501182A HUP0501182A HUP0501182A3 HU P0501182 A3 HUP0501182 A3 HU P0501182A3 HU 0501182 A HU0501182 A HU 0501182A HU P0501182 A HUP0501182 A HU P0501182A HU P0501182 A3 HUP0501182 A3 HU P0501182A3
- Authority
- HU
- Hungary
- Prior art keywords
- metallproteases
- inhibitors
- pharmaceutical compositions
- compositions containing
- alkane derivatives
- Prior art date
Links
- -1 Aza spiro alkane Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/10—Spiro-condensed systems
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PCT/US2004/012672 WO2004096139A2 (en) | 2003-04-24 | 2004-04-23 | Aza spiro alkane derivatives as inhibitors of metalloproteases |
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HUP0501182A3 true HUP0501182A3 (en) | 2011-08-29 |
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HU0501182A HUP0501182A3 (en) | 2003-04-24 | 2004-04-23 | Aza spiro alkane derivatives as inhibitors of metallproteases and pharmaceutical compositions containing them |
HUE04760368A HUE026904T2 (hu) | 2003-04-24 | 2004-04-23 | Aza-spiro-alkán-származékok metalloproteázok inhibitoraiként |
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