PH12012501331A1 - Cyclic amide derivatives, and their production and use as antithrombotic agentss - Google Patents
Cyclic amide derivatives, and their production and use as antithrombotic agentssInfo
- Publication number
- PH12012501331A1 PH12012501331A1 PH1/2012/501331A PH12012501331A PH12012501331A1 PH 12012501331 A1 PH12012501331 A1 PH 12012501331A1 PH 12012501331 A PH12012501331 A PH 12012501331A PH 12012501331 A1 PH12012501331 A1 PH 12012501331A1
- Authority
- PH
- Philippines
- Prior art keywords
- optionally substituted
- cyclic amide
- agentss
- antithrombotic
- bond
- Prior art date
Links
- 150000003950 cyclic amides Chemical class 0.000 title abstract 2
- 230000002785 anti-thrombosis Effects 0.000 title 1
- 239000003146 anticoagulant agent Substances 0.000 title 1
- 125000002947 alkylene group Chemical group 0.000 abstract 3
- 125000004450 alkenylene group Chemical group 0.000 abstract 2
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004152000 | 2004-05-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12012501331A1 true PH12012501331A1 (en) | 2013-06-17 |
Family
ID=34968275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH1/2012/501331A PH12012501331A1 (en) | 2004-05-21 | 2005-05-20 | Cyclic amide derivatives, and their production and use as antithrombotic agentss |
Country Status (26)
| Country | Link |
|---|---|
| US (4) | US7745623B2 (OSRAM) |
| EP (2) | EP2208726B1 (OSRAM) |
| JP (2) | JP4129047B2 (OSRAM) |
| KR (1) | KR101248637B1 (OSRAM) |
| CN (2) | CN102093285B (OSRAM) |
| AT (1) | ATE513813T1 (OSRAM) |
| AU (1) | AU2005245298B2 (OSRAM) |
| BR (1) | BRPI0511186A (OSRAM) |
| CA (1) | CA2567506C (OSRAM) |
| CY (1) | CY1111850T1 (OSRAM) |
| DK (1) | DK1748985T3 (OSRAM) |
| ES (1) | ES2368155T3 (OSRAM) |
| HR (1) | HRP20110640T1 (OSRAM) |
| IL (1) | IL178896A (OSRAM) |
| MX (1) | MXPA06013243A (OSRAM) |
| MY (1) | MY154461A (OSRAM) |
| NO (1) | NO20065929L (OSRAM) |
| NZ (1) | NZ550985A (OSRAM) |
| PH (1) | PH12012501331A1 (OSRAM) |
| PL (1) | PL1748985T3 (OSRAM) |
| PT (1) | PT1748985E (OSRAM) |
| RS (1) | RS51925B (OSRAM) |
| RU (1) | RU2361861C2 (OSRAM) |
| SI (1) | SI1748985T1 (OSRAM) |
| TW (1) | TWI396686B (OSRAM) |
| WO (1) | WO2005113504A1 (OSRAM) |
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| AU2001269531A1 (en) * | 2000-07-17 | 2002-01-30 | Takeda Chemical Industries Ltd. | Sulfone derivatives, process for their production and use thereof |
| EP1564213A4 (en) * | 2002-11-22 | 2009-05-27 | Takeda Pharmaceutical | IMIDAZOLE DERIVATIVE, METHOD FOR THE PRODUCTION AND USE THEREOF |
| TWI396686B (zh) | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
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| US20110045028A1 (en) * | 2006-11-30 | 2011-02-24 | Takeda Pharmaceutical Company Limited | Sustained release preparation |
| TW201014850A (en) | 2008-09-25 | 2010-04-16 | Takeda Pharmaceutical | Solid pharmaceutical composition |
| JP5535931B2 (ja) | 2008-10-27 | 2014-07-02 | 武田薬品工業株式会社 | 二環性化合物 |
| WO2010076884A1 (ja) | 2008-12-29 | 2010-07-08 | 武田薬品工業株式会社 | 新規縮合環化合物およびその用途 |
| AR075158A1 (es) | 2009-01-27 | 2011-03-16 | Takeda Pharmaceutical | Derivados de pirrolopirimidinas, composiciones farmaceuticas y usos. |
| BRPI1014388A2 (pt) | 2009-04-30 | 2016-04-05 | Takeda Pharmaceutical | preparação de sólido. |
| US20120172351A1 (en) | 2009-06-09 | 2012-07-05 | Nobuyuki Negoro | Novel fused cyclic compound and use thereof |
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| US8221489B2 (en) * | 2009-08-20 | 2012-07-17 | Stentys | Device and method for treating a body lumen |
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| BR112012032055B8 (pt) | 2010-06-16 | 2019-11-12 | Takeda Pharmaceuticals Co | cristal de cloridrato de 1-(4-metoxibutil)-n-(2-metilpropil)-n-[(3s,5r)-5-(morfolin-4-ilcarbonil)piperidin-3-il]-1h-benzimidazol-2-carboxamida, medicamento, e, uso do cristal |
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| JP5816626B2 (ja) | 2010-09-17 | 2015-11-18 | 武田薬品工業株式会社 | 糖尿病治療剤 |
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| US9181186B2 (en) | 2012-02-13 | 2015-11-10 | Takeda Pharmaceutical Company Limited | Aromatic ring compound |
| JP6077555B2 (ja) | 2012-02-15 | 2017-02-08 | 武田薬品工業株式会社 | 錠剤 |
| CN104254525B (zh) | 2012-02-24 | 2016-05-25 | 武田药品工业株式会社 | 芳环化合物 |
| US9073864B2 (en) | 2012-03-29 | 2015-07-07 | Takeda Pharmaceutical Company Limted | Aromatic ring compound |
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| JPWO2013168760A1 (ja) | 2012-05-10 | 2016-01-07 | 武田薬品工業株式会社 | 芳香環化合物 |
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| CN103936763B (zh) * | 2013-01-18 | 2017-10-31 | 中国科学院上海药物研究所 | 噁唑烷酮类化合物及其制备方法和用途 |
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| SI3031799T1 (en) | 2013-08-09 | 2018-07-31 | Takeda Pharmaceutical Company Limited | Aromatic compound |
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-
2005
- 2005-05-19 TW TW094116243A patent/TWI396686B/zh not_active IP Right Cessation
- 2005-05-20 KR KR1020067023942A patent/KR101248637B1/ko not_active Expired - Fee Related
- 2005-05-20 BR BRPI0511186-2A patent/BRPI0511186A/pt not_active Application Discontinuation
- 2005-05-20 MY MYPI20052298A patent/MY154461A/en unknown
- 2005-05-20 DK DK05743594.3T patent/DK1748985T3/da active
- 2005-05-20 JP JP2007521014A patent/JP4129047B2/ja not_active Expired - Fee Related
- 2005-05-20 CN CN2010105739971A patent/CN102093285B/zh not_active Expired - Fee Related
- 2005-05-20 RU RU2006145449/04A patent/RU2361861C2/ru not_active IP Right Cessation
- 2005-05-20 AU AU2005245298A patent/AU2005245298B2/en not_active Ceased
- 2005-05-20 HR HR20110640T patent/HRP20110640T1/hr unknown
- 2005-05-20 RS RS20110371A patent/RS51925B/sr unknown
- 2005-05-20 AT AT05743594T patent/ATE513813T1/de active
- 2005-05-20 ES ES05743594T patent/ES2368155T3/es not_active Expired - Lifetime
- 2005-05-20 SI SI200531321T patent/SI1748985T1/sl unknown
- 2005-05-20 PT PT05743594T patent/PT1748985E/pt unknown
- 2005-05-20 NZ NZ550985A patent/NZ550985A/en not_active IP Right Cessation
- 2005-05-20 PL PL05743594T patent/PL1748985T3/pl unknown
- 2005-05-20 WO PCT/JP2005/009711 patent/WO2005113504A1/en not_active Ceased
- 2005-05-20 CN CN2005800244522A patent/CN1989104B/zh not_active Expired - Fee Related
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- 2005-05-20 CA CA2567506A patent/CA2567506C/en not_active Expired - Fee Related
- 2005-05-20 EP EP10161428.7A patent/EP2208726B1/en not_active Expired - Lifetime
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- 2006-12-20 NO NO20065929A patent/NO20065929L/no not_active Application Discontinuation
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- 2008-01-15 JP JP2008006003A patent/JP4362535B2/ja not_active Expired - Fee Related
- 2008-06-11 US US12/157,573 patent/US20080255362A1/en not_active Abandoned
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