NO20061832L - Karboksamidderivat av amidtype - Google Patents

Karboksamidderivat av amidtype

Info

Publication number
NO20061832L
NO20061832L NO20061832A NO20061832A NO20061832L NO 20061832 L NO20061832 L NO 20061832L NO 20061832 A NO20061832 A NO 20061832A NO 20061832 A NO20061832 A NO 20061832A NO 20061832 L NO20061832 L NO 20061832L
Authority
NO
Norway
Prior art keywords
halogen
derivative
lower alkyl
amide type
salts
Prior art date
Application number
NO20061832A
Other languages
English (en)
Inventor
Takayuki Kawaguchi
Hidenori Akatsuka
Masamichi Morimoto
Tatsuya Watanabe
Toru Iijima
Jun Murakami
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of NO20061832L publication Critical patent/NO20061832L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Karboksamidderivat av amidtype med generell formel [1]: hvor X er -N= eller -CH=; R1 er halogen, lavere alkyl etc; R2 har formel [2] Y1 og Y2 er like eller forskjellige og er halogen eller en gruppe valgt blant lavere alkyl, lavere alkoksy etc.; og ring A er fenyl etc. Det beskrives også farmakologisk akseptable salter av derivatet. Derivatet og saltene er anvendelige som medisin, særlig som en FXa-inhibitor. hvor X er -N= eller -CH=; R1 er halogen, lavere alkyl etc; R2 har formel [2] Y1 og Y2 er like eller forskjellige og er halogen eller en gruppe valgt blant lavere alkyl, lavere alkoksy etc.; og ring A er fenyl etc. Det beskrives også farmakologisk akseptable salter av derivatet. Derivatet og saltene er anvendelige som medisin, særlig som en FXa-inhibitor.
NO20061832A 2003-09-26 2006-04-25 Karboksamidderivat av amidtype NO20061832L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003334595 2003-09-26
PCT/JP2004/013892 WO2005030706A1 (ja) 2003-09-26 2004-09-24 アミド型カルボキサミド誘導体

Publications (1)

Publication Number Publication Date
NO20061832L true NO20061832L (no) 2006-04-25

Family

ID=34386034

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061832A NO20061832L (no) 2003-09-26 2006-04-25 Karboksamidderivat av amidtype

Country Status (17)

Country Link
US (1) US7375119B2 (no)
EP (1) EP1666455A4 (no)
JP (1) JP4571075B2 (no)
KR (1) KR100740820B1 (no)
CN (1) CN100475777C (no)
AR (1) AR045816A1 (no)
AU (1) AU2004276128B2 (no)
BR (1) BRPI0414460A (no)
CA (1) CA2538072C (no)
IL (1) IL174188A0 (no)
MX (1) MXPA06003382A (no)
NO (1) NO20061832L (no)
NZ (1) NZ546160A (no)
RU (1) RU2307829C2 (no)
TW (1) TW200512181A (no)
WO (1) WO2005030706A1 (no)
ZA (1) ZA200602131B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7875627B2 (en) * 2004-12-07 2011-01-25 Abbott Laboratories Thienopyridyl compounds that inhibit vanilloid receptor subtype 1 (VR1) and uses thereof
TW200734304A (en) * 2005-11-08 2007-09-16 Astellas Pharma Inc Benzene derivative or salt thereof
CN102250074A (zh) * 2006-11-15 2011-11-23 沃泰克斯药物(加拿大)股份有限公司 用于治疗或预防黄病毒属感染的噻吩类似物
ES2368286T3 (es) 2007-02-02 2011-11-16 Pfizer Products Inc. Compuestos tricíclicos y su uso como moduladores de los receptores de glucocorticoides.
EP2070925A1 (de) 2007-12-10 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Neue 2-substituierte Tiazol-4-carbonsäureamid-Derivative deren Herstellung und Verwendung als Arzneimittel
EP2070924A1 (de) 2007-12-10 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Neue 2-Hetarylthiazol-4-carbonsäureamid-Derivative, deren Herstellung und Verwendung als Arzneimittel
EP2070916A1 (de) 2007-12-10 2009-06-17 Bayer Schering Pharma Aktiengesellschaft 2-Aryl-thiazol-4-carbonsäureamid-Derivate, deren Herstellung und Verwendung als Arzneimittel
US8178583B2 (en) * 2008-12-19 2012-05-15 Hoffmann-La Roche Inc. Compounds
US9186349B2 (en) * 2009-05-12 2015-11-17 Mallinckrodt Llc Diaza heterocyclic compounds for phototherapy
US20130261130A1 (en) * 2010-11-01 2013-10-03 Shaheen Ahmed Neurotrypsin inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL133621A0 (en) * 1997-06-26 2001-04-30 Lilly Co Eli Antithrombotic agents
ATE260103T1 (de) 1997-12-19 2004-03-15 Schering Ag Ortho-anthranilamide derivate als antikoagulantien
EP0937711A1 (de) 1998-02-18 1999-08-25 Roche Diagnostics GmbH Neue Thiobenzamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
US6956988B2 (en) 1998-08-21 2005-10-18 Avanex Corporation Optical interleaver
JP2002533454A (ja) * 1998-12-23 2002-10-08 イーライ・リリー・アンド・カンパニー 芳香族アミド類
CA2385592C (en) * 1999-09-17 2011-01-11 Bing-Yan Zhu Benzamides and related inhibitors of factor xa
US7112594B2 (en) 2000-08-09 2006-09-26 Mitsubishi Pharma Corporation Fused bicyclic amide compounds and medicinal use thereof
US7163938B2 (en) * 2000-11-28 2007-01-16 Eli Lilly And Company Substituted carboxamides
US7312235B2 (en) 2001-03-30 2007-12-25 Millennium Pharmaceuticals, Inc. Benzamide inhibitors of factor Xa
EP1373194B1 (en) * 2001-03-30 2007-08-01 Millennium Pharmaceuticals, Inc. BENZAMIDE INHIBITORS OF FACTOR Xa
DE60233335D1 (de) * 2001-09-21 2009-09-24 Bristol Myers Squibb Co Lactamhaltige verbindungen und ihre derivate als faktor-xa-hemmer
WO2003048081A2 (en) * 2001-12-04 2003-06-12 Bristol-Myers Squibb Company Glycinamides as factor xa inhibitors
EP1489078B1 (en) 2002-03-28 2010-01-06 Mitsubishi Tanabe Pharma Corporation Benzofuran derivative
JP2005104838A (ja) * 2003-01-09 2005-04-21 Tanabe Seiyaku Co Ltd 縮合フラン化合物

Also Published As

Publication number Publication date
JP4571075B2 (ja) 2010-10-27
RU2006114055A (ru) 2006-09-10
CN100475777C (zh) 2009-04-08
AU2004276128A1 (en) 2005-04-07
WO2005030706A1 (ja) 2005-04-07
AU2004276128B2 (en) 2007-11-29
MXPA06003382A (es) 2006-06-08
CA2538072C (en) 2009-08-25
KR100740820B1 (ko) 2007-07-19
EP1666455A4 (en) 2009-02-25
EP1666455A1 (en) 2006-06-07
JPWO2005030706A1 (ja) 2006-12-07
RU2307829C2 (ru) 2007-10-10
TW200512181A (en) 2005-04-01
NZ546160A (en) 2008-09-26
CA2538072A1 (en) 2005-04-07
ZA200602131B (en) 2007-02-28
KR20060095982A (ko) 2006-09-05
US7375119B2 (en) 2008-05-20
US20060287329A1 (en) 2006-12-21
CN1860097A (zh) 2006-11-08
BRPI0414460A (pt) 2006-11-14
IL174188A0 (en) 2006-08-01
AR045816A1 (es) 2005-11-16

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