NO20061831L - Benzofuranderivater av karbamoyltype - Google Patents

Benzofuranderivater av karbamoyltype

Info

Publication number
NO20061831L
NO20061831L NO20061831A NO20061831A NO20061831L NO 20061831 L NO20061831 L NO 20061831L NO 20061831 A NO20061831 A NO 20061831A NO 20061831 A NO20061831 A NO 20061831A NO 20061831 L NO20061831 L NO 20061831L
Authority
NO
Norway
Prior art keywords
carbamoyl
benzofuran derivatives
formula
group
optionally substituted
Prior art date
Application number
NO20061831A
Other languages
English (en)
Inventor
Takayuki Kawaguchi
Hidenori Akatsuka
Masamichi Morimoto
Tatsuya Watanabe
Toru Iijima
Jun Murakami
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of NO20061831L publication Critical patent/NO20061831L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

Benzofuranderivater av karbamoyltype med generell formel [1] eller et farmakologisk akseptabelt salt derav, er anvendelig som legemidler, så som FXa-inhibitor:. hvohvor Z er en gruppe med formel:. hvor A er en fri enkeltbinding, Y er en sykloalkandiylgruppe, Rog Rer like eller forskjellige og er en eventuelt substituert gruppe med lavere alkyl, Rer halogenatom, ring B har formel: og er en eventuelt substituert benzenring, og Rer hydrogen.
NO20061831A 2003-09-26 2006-04-25 Benzofuranderivater av karbamoyltype NO20061831L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003334597 2003-09-26
PCT/JP2004/013891 WO2005030759A1 (ja) 2003-09-26 2004-09-24 カルバモイル型ベンゾフラン誘導体

Publications (1)

Publication Number Publication Date
NO20061831L true NO20061831L (no) 2006-04-25

Family

ID=34386035

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061831A NO20061831L (no) 2003-09-26 2006-04-25 Benzofuranderivater av karbamoyltype

Country Status (18)

Country Link
US (1) US7605158B2 (no)
EP (1) EP1666478A4 (no)
JP (1) JP4277022B2 (no)
KR (1) KR100763294B1 (no)
CN (1) CN100430392C (no)
AR (1) AR046027A1 (no)
AU (1) AU2004276127B2 (no)
BR (1) BRPI0414597A (no)
CA (1) CA2539471A1 (no)
IL (1) IL174187A0 (no)
MX (1) MXPA06003378A (no)
MY (1) MY139258A (no)
NO (1) NO20061831L (no)
NZ (1) NZ546159A (no)
RU (1) RU2319700C1 (no)
TW (1) TW200524915A (no)
WO (1) WO2005030759A1 (no)
ZA (1) ZA200602130B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1489078B1 (en) * 2002-03-28 2010-01-06 Mitsubishi Tanabe Pharma Corporation Benzofuran derivative
US20070049748A1 (en) * 2005-08-26 2007-03-01 Uppala Venkata Bhaskara R Preparation of ezetimibe
US9647851B2 (en) * 2008-10-13 2017-05-09 Ppc Broadband, Inc. Ingress noise inhibiting network interface device and method for cable television networks
WO2013192517A2 (en) * 2012-06-21 2013-12-27 Whitehead Institute For Biomedical Research Compounds for treating infectious diseases
CN107205927A (zh) * 2014-11-10 2017-09-26 葛兰素史克知识产权第二有限公司 用于丙型肝炎的长效药物组合物
US11696928B2 (en) * 2017-11-03 2023-07-11 Universite De Montreal Compounds and use thereof in the expansion of stem cells and/or progenitor cells
CN110407697A (zh) * 2019-08-28 2019-11-05 上海毕得医药科技有限公司 一种4-甲酰基-3-羟基苯甲酸甲酯的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2168858A1 (en) 1994-06-06 1995-12-14 Shinichiro Ono Novel fused-ring carboxylic acid compound or salt thereof, and medicinal use thereof
US6140351A (en) 1997-12-19 2000-10-31 Berlex Laboratories, Inc. Ortho-anthranilamide derivatives as anti-coagulants
ATE260103T1 (de) 1997-12-19 2004-03-15 Schering Ag Ortho-anthranilamide derivate als antikoagulantien
EP0937711A1 (de) 1998-02-18 1999-08-25 Roche Diagnostics GmbH Neue Thiobenzamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
JP2002533454A (ja) 1998-12-23 2002-10-08 イーライ・リリー・アンド・カンパニー 芳香族アミド類
CA2385592C (en) 1999-09-17 2011-01-11 Bing-Yan Zhu Benzamides and related inhibitors of factor xa
US6720317B1 (en) 1999-09-17 2004-04-13 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
US7112594B2 (en) 2000-08-09 2006-09-26 Mitsubishi Pharma Corporation Fused bicyclic amide compounds and medicinal use thereof
EP1373194B1 (en) 2001-03-30 2007-08-01 Millennium Pharmaceuticals, Inc. BENZAMIDE INHIBITORS OF FACTOR Xa
EP1489078B1 (en) * 2002-03-28 2010-01-06 Mitsubishi Tanabe Pharma Corporation Benzofuran derivative
JP2005104838A (ja) * 2003-01-09 2005-04-21 Tanabe Seiyaku Co Ltd 縮合フラン化合物

Also Published As

Publication number Publication date
AU2004276127A1 (en) 2005-04-07
CN1856488A (zh) 2006-11-01
AU2004276127B2 (en) 2008-02-07
JPWO2005030759A1 (ja) 2006-12-07
CN100430392C (zh) 2008-11-05
BRPI0414597A (pt) 2006-11-07
RU2006114056A (ru) 2007-11-10
US20060247273A1 (en) 2006-11-02
ZA200602130B (en) 2007-03-28
JP4277022B2 (ja) 2009-06-10
WO2005030759A1 (ja) 2005-04-07
CA2539471A1 (en) 2005-04-07
NZ546159A (en) 2009-06-26
AR046027A1 (es) 2005-11-23
TW200524915A (en) 2005-08-01
US7605158B2 (en) 2009-10-20
EP1666478A4 (en) 2008-12-03
MY139258A (en) 2009-09-30
RU2319700C1 (ru) 2008-03-20
IL174187A0 (en) 2006-08-01
KR100763294B1 (ko) 2007-10-04
KR20060073963A (ko) 2006-06-29
MXPA06003378A (es) 2006-06-08
EP1666478A1 (en) 2006-06-07

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Legal Events

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