NO20071319L - Fremgangsmate for fremstilling av isotiazolderivater. - Google Patents

Fremgangsmate for fremstilling av isotiazolderivater.

Info

Publication number
NO20071319L
NO20071319L NO20071319A NO20071319A NO20071319L NO 20071319 L NO20071319 L NO 20071319L NO 20071319 A NO20071319 A NO 20071319A NO 20071319 A NO20071319 A NO 20071319A NO 20071319 L NO20071319 L NO 20071319L
Authority
NO
Norway
Prior art keywords
preparation
isothiazole derivatives
isothiazole
derivatives
prodrugs
Prior art date
Application number
NO20071319A
Other languages
English (en)
Inventor
David B Damon
Brian P Jones
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20071319L publication Critical patent/NO20071319L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Fremgangsmåter og intermediater for fremstilling av forbindelser med formel (I) og farmasøytiske akseptable salter, prodrugs, solvater og hydrater derav, hvori R1, R2 og R3 har definisjonene tilveiebragt heri.
NO20071319A 2004-08-26 2007-03-09 Fremgangsmate for fremstilling av isotiazolderivater. NO20071319L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60454204P 2004-08-26 2004-08-26
PCT/US2005/027398 WO2006026034A2 (en) 2004-08-26 2005-08-02 Processes for the preparation of isothiazole derivatives

Publications (1)

Publication Number Publication Date
NO20071319L true NO20071319L (no) 2007-05-29

Family

ID=36000502

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071319A NO20071319L (no) 2004-08-26 2007-03-09 Fremgangsmate for fremstilling av isotiazolderivater.

Country Status (22)

Country Link
US (2) US8884025B2 (no)
EP (1) EP1784183B1 (no)
JP (2) JP5100390B2 (no)
KR (1) KR100893977B1 (no)
CN (1) CN101043888B (no)
AR (1) AR050613A1 (no)
AT (1) ATE542533T1 (no)
AU (1) AU2005280451B2 (no)
BR (1) BRPI0514667A (no)
CA (1) CA2578023C (no)
DK (1) DK1784183T3 (no)
ES (1) ES2378994T3 (no)
HK (1) HK1111359A1 (no)
IL (1) IL181063A0 (no)
MX (1) MX2007002246A (no)
NO (1) NO20071319L (no)
PL (1) PL1784183T3 (no)
PT (1) PT1784183E (no)
RU (1) RU2349588C2 (no)
TW (1) TWI361688B (no)
WO (1) WO2006026034A2 (no)
ZA (1) ZA200701016B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8884025B2 (en) 2004-08-26 2014-11-11 David B. Damon Processes for the preparation of isothiazole derivatives
ES2851602T3 (es) 2011-12-28 2021-09-08 Allergan Inc Derivados de 3-fenil-5-ureidoisotiazol-4-carboxamida como inhibidores de cinasa
CN103833665B (zh) * 2014-02-24 2015-09-23 杰达维（上海）医药科技发展有限公司 一种新的合成异噻唑的方法
US9353093B2 (en) 2014-10-07 2016-05-31 Allergan, Inc. Indole-1-carboxamides as kinase inhibitors
US9403803B2 (en) 2014-10-08 2016-08-02 Allergan, Inc. Indole-3-carboxamides as kinase inhibitors
US9359336B2 (en) 2014-10-09 2016-06-07 Allergan, Inc. Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors
US9371314B2 (en) 2014-10-09 2016-06-21 Allergan, Inc. Pyridyl benzothiophenes as kinase inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2408234A1 (de) * 1974-02-21 1975-09-04 Celamerck Gmbh & Co Kg Isothiazolylharnstoffe
US4059433A (en) * 1976-06-18 1977-11-22 Fmc Corporation 3-Alkoxyisothiazole derivatives as herbicides
IL72093A0 (en) * 1983-06-20 1984-10-31 Lilly Co Eli N'-substituted(3-alkyl-5-isothiazolyl)urea derivatives
UA60365C2 (uk) 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
HN2000000051A (es) * 1999-05-19 2001-02-02 Pfizer Prod Inc Derivados heterociclicos utiles como agentes anticancerosos
JP4511352B2 (ja) * 2002-07-25 2010-07-28 ファイザー・インク 抗癌薬として有用なイソチアゾール誘導体
US20060035954A1 (en) * 2004-08-11 2006-02-16 Sharma Padam N Ammonolysis process for the preparation of intermediates for DPP IV inhibitors
US8884025B2 (en) 2004-08-26 2014-11-11 David B. Damon Processes for the preparation of isothiazole derivatives

Also Published As

Publication number Publication date
JP5498524B2 (ja) 2014-05-21
JP5100390B2 (ja) 2012-12-19
CN101043888A (zh) 2007-09-26
TWI361688B (en) 2012-04-11
JP2008510841A (ja) 2008-04-10
TW200621241A (en) 2006-07-01
EP1784183B1 (en) 2012-01-25
PL1784183T3 (pl) 2012-07-31
AU2005280451A1 (en) 2006-03-09
RU2349588C2 (ru) 2009-03-20
EP1784183A2 (en) 2007-05-16
ATE542533T1 (de) 2012-02-15
MX2007002246A (es) 2007-04-20
CN101043888B (zh) 2010-08-11
EP1784183A4 (en) 2009-12-09
ES2378994T3 (es) 2012-04-19
KR20070070158A (ko) 2007-07-03
US20150065726A1 (en) 2015-03-05
WO2006026034A3 (en) 2006-06-29
WO2006026034A2 (en) 2006-03-09
DK1784183T3 (da) 2012-04-02
KR100893977B1 (ko) 2009-04-20
JP2012153705A (ja) 2012-08-16
PT1784183E (pt) 2012-03-09
RU2007106847A (ru) 2008-08-27
CA2578023C (en) 2012-05-15
HK1111359A1 (en) 2008-08-08
US8884025B2 (en) 2014-11-11
ZA200701016B (en) 2008-05-28
US20090023924A1 (en) 2009-01-22
AR050613A1 (es) 2006-11-08
US9371298B2 (en) 2016-06-21
CA2578023A1 (en) 2006-03-09
BRPI0514667A (pt) 2008-06-17
AU2005280451B2 (en) 2009-02-05
IL181063A0 (en) 2007-07-04

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application