NZ720282A - Heteroaryl derivatives as cftr modulators - Google Patents

Heteroaryl derivatives as cftr modulators

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Publication number
NZ720282A
NZ720282A NZ720282A NZ72028209A NZ720282A NZ 720282 A NZ720282 A NZ 720282A NZ 720282 A NZ720282 A NZ 720282A NZ 72028209 A NZ72028209 A NZ 72028209A NZ 720282 A NZ720282 A NZ 720282A
Authority
NZ
New Zealand
Prior art keywords
disease
hereditary
type
deficiency
useful
Prior art date
Application number
NZ720282A
Other languages
English (en)
Inventor
Sara Hadida-Ruah
Mark Miller
Jinglan Zhou
Brian Bear
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Priority to NZ736561A priority Critical patent/NZ736561A/en
Publication of NZ720282A publication Critical patent/NZ720282A/en

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    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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