US5298627A
(en)
*
|
1993-03-03 |
1994-03-29 |
Warner-Lambert Company |
Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
|
DE4415331A1
(de)
*
|
1994-05-02 |
1995-11-09 |
Sobrevin |
Fadenspeichervorrichtung mit einstellbarem Fadenabzugswiderstand
|
US5385929A
(en)
*
|
1994-05-04 |
1995-01-31 |
Warner-Lambert Company |
[(Hydroxyphenylamino) carbonyl] pyrroles
|
HRP960312B1
(en)
|
1995-07-17 |
2001-10-31 |
Warner Lambert Co |
NOVEL PROCESS FOR THE PRODUCTION OF AMORPHOUS /R-(R*, R*)/-2-(4-FLUOROPHENYL)-"beta", "delta"-DIHYDROXY-5-PHENYL-4-/(PHENYLAMINO)CARBONYL/-1H-PYRROLE -1-HEPTANOIC ACID CALCIUM SALT (2 : 1)
|
US6087511A
(en)
*
|
1996-07-16 |
2000-07-11 |
Warner-Lambert Company |
Process for the production of amorphous [R-(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl )-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid) calcium salt (2:1)
|
US20030105154A1
(en)
*
|
2001-10-24 |
2003-06-05 |
Bisgaier Charles Larry |
Statin-carboxyalkylether combinations
|
KR100668575B1
(ko)
*
|
1997-12-19 |
2007-01-17 |
워너-램버트 익스포트 리미티드 |
1,3-디올의 합성방법
|
SI20109A
(sl)
*
|
1998-12-16 |
2000-06-30 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Stabilna farmacevtska formulacija
|
IN191236B
(no)
*
|
1999-05-25 |
2003-10-11 |
Ranbaxy Lab Ltd |
|
US20040063969A1
(en)
*
|
1999-10-18 |
2004-04-01 |
Egis Gyogyszergyar Rt. |
Process for the preparation of amorphous atorvastatin calcium
|
US7411075B1
(en)
|
2000-11-16 |
2008-08-12 |
Teva Pharmaceutical Industries Ltd. |
Polymorphic form of atorvastatin calcium
|
WO2001044181A1
(en)
*
|
1999-12-17 |
2001-06-21 |
Warner Lambert Research And Development Ireland Limited |
A process for producing crystalline atorvastatin calcium
|
WO2001044180A1
(en)
|
1999-12-17 |
2001-06-21 |
Warner Lambert Research And Development Ireland Limited |
A factory scale process for producing crystalline atorvastatin trihydrate hemi calcium salt
|
US7300775B2
(en)
*
|
1999-12-29 |
2007-11-27 |
Verenium Corporation |
Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
|
US20040014195A1
(en)
*
|
1999-12-29 |
2004-01-22 |
Diversa Corporation |
Nitrilases, nucleic acids encoding them and methods for making and using them
|
US7521216B2
(en)
|
1999-12-29 |
2009-04-21 |
Verenium Corporation |
Nitrilases and methods for making and using them
|
US7608445B1
(en)
|
1999-12-29 |
2009-10-27 |
Verenium Corporation |
Nitrilases, nucleic acids encoding them and methods for making and using them
|
US6528661B2
(en)
*
|
2000-11-16 |
2003-03-04 |
Teva Pharmaceutical Industries Ltd. |
Hydrolysis of [R(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino) carbonyl]-1H-pyrrole-1-heptanoic acid esters with calcium hydroxide
|
IL156055A0
(en)
*
|
2000-11-30 |
2003-12-23 |
Teva Pharma |
Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms
|
US7501450B2
(en)
*
|
2000-11-30 |
2009-03-10 |
Teva Pharaceutical Industries Ltd. |
Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
|
NZ527048A
(en)
*
|
2000-12-27 |
2004-12-24 |
Ciba Sc Holding Ag |
Crystalline forms of atorvastatin
|
EP1728785A1
(en)
*
|
2001-01-09 |
2006-12-06 |
Warner-Lambert Company LLC |
7-[(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-pyrrol-1-yl]-heptanoic acid ester 3,5-dioxo-acetal
|
US6476235B2
(en)
*
|
2001-01-09 |
2002-11-05 |
Warner-Lambert Company |
Process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide
|
WO2002057229A1
(en)
*
|
2001-01-19 |
2002-07-25 |
Biocon India Limited |
FORM V CRYSTALLINE [R-(R*,R*)]-2-(4-FLUOROPHENYL)-ß,$G(D)-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1- HEPTANOIC ACID HEMI CALCIUM SALT. (ATORVASTATIN)
|
SI20814A
(sl)
|
2001-01-23 |
2002-08-31 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Priprava amorfnega atorvastatina
|
SI20848A
(sl)
|
2001-03-14 |
2002-10-31 |
Lek, Tovarna Farmacevtskih In Kemijskih Izdelkov, D.D. |
Farmacevtska formulacija, ki vsebuje atorvastatin kalcij
|
IL158790A0
(en)
|
2001-06-29 |
2004-05-12 |
Warner Lambert Co |
Crystalline forms of [r-(*,r*)]-2-(4-fluorophenyl) -beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino) carbonyl]-1h-pyrrole-1-heptanoic acid calcium salt (2:1) (atorvastatin)
|
US7199261B2
(en)
*
|
2001-07-06 |
2007-04-03 |
Teva Pharmaceutical Industries Ltd |
Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives
|
CZ2004158A3
(cs)
*
|
2001-07-06 |
2005-01-12 |
Teva Pharmaceutical Industries Ltd. |
Syntéza a meziprodukty derivátů 3,5-dihydroxyheptanové kyseliny
|
US7074818B2
(en)
*
|
2001-07-30 |
2006-07-11 |
Dr. Reddy's Laboratories Limited |
Crystalline forms VI and VII of Atorvastatin calcium
|
IL159626A0
(en)
|
2001-07-30 |
2004-06-01 |
Reddys Lab Ltd Dr |
Crystalline forms of atorvastatin calcium and processes for the preparation thereof
|
KR20040026705A
(ko)
*
|
2001-08-16 |
2004-03-31 |
테바 파마슈티컬 인더스트리즈 리미티드 |
스타틴의 칼슘 염 형태의 제조 방법
|
CA2456095C
(en)
*
|
2001-08-31 |
2010-05-11 |
Morepen Laboratories Ltd. |
An improved process for the preparation of amorphous atorvastatin calcium salt (2:1)
|
CA2412012C
(en)
*
|
2001-11-20 |
2011-08-02 |
Ed. Geistlich Soehne Ag Fuer Chemische Industrie |
Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage
|
US20060020137A1
(en)
*
|
2001-11-29 |
2006-01-26 |
Limor Tessler |
Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
|
UA77990C2
(en)
*
|
2001-12-12 |
2007-02-15 |
|
Crystalline calcium salt of (2:1) [r-(r*,r*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrroleheptanic acid
|
CZ296967B6
(cs)
|
2002-02-01 |
2006-08-16 |
Zentiva, A.S. |
Zpusob výroby amorfní formy hemivápenaté soli (3R,5R) 7-[3-fenyl-4-fenylkarbamoyl-2-(4-fluorfenyl)-5-isopropylpyrrol-1-yl]-3,5-dihydroxyheptanové kyseliny (atorvastatinu)
|
KR20090045419A
(ko)
*
|
2002-02-19 |
2009-05-07 |
테바 파마슈티컬 인더스트리즈 리미티드 |
아토르바스타틴 헤미-칼슘 용매화합물의 탈용매화
|
DE10212492B4
(de)
*
|
2002-03-21 |
2012-02-02 |
Daimler Ag |
Kolbenpumpe
|
AU2003226051A1
(en)
*
|
2002-04-16 |
2003-11-03 |
Banyu Pharmaceutical Co., Ltd. |
Solid forms of salts with tyrosine kinase activity
|
AU2003251523A1
(en)
|
2002-06-13 |
2003-12-31 |
Diversa Corporation |
Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid
|
US20060211761A1
(en)
*
|
2002-07-08 |
2006-09-21 |
Yatendra Kumar |
Hmg-coa-reductase inhibitors
|
US7078430B2
(en)
*
|
2002-07-08 |
2006-07-18 |
Ranbaxy Laboratories Limited |
HMG CoA-reductase inhibitors
|
PL375415A1
(en)
*
|
2002-08-06 |
2005-11-28 |
Warner-Lambert Company Llc |
Process for preparing 5-(4-fluorophenyl)-1-[2-((2r,4r)-4-hydroxy -6-oxo-tetrahydro-pyran-2-yl)ethyl]-2-isopropyl-4-phenyl-1h-pyrrole-3-carboxylic acid phenylamide
|
AU2002330735A1
(en)
*
|
2002-09-03 |
2004-03-29 |
Morepen Laboratories Limited |
Atorvastatin calcium form vi or hydrates thereof
|
SI21302A
(sl)
*
|
2002-10-11 |
2004-04-30 |
LEK farmacevtska dru�ba d.d. |
Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino
|
HRP20020885B1
(en)
*
|
2002-11-11 |
2007-05-31 |
GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. |
SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
|
EP1424324A1
(en)
*
|
2002-11-28 |
2004-06-02 |
Teva Pharmaceutical Industries Limited |
Crystalline form F of Atorvastatin hemi-calcium salt
|
US20040198800A1
(en)
*
|
2002-12-19 |
2004-10-07 |
Geoffrey Allan |
Lipoxygenase inhibitors as hypolipidemic and anti-hypertensive agents
|
US20040132771A1
(en)
*
|
2002-12-20 |
2004-07-08 |
Pfizer Inc |
Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
|
EP1961419B1
(en)
|
2002-12-20 |
2010-03-24 |
Pfizer Products Inc. |
Dosage forms comprising a CETP inhibitor and an HMG-CoA reductase inhibitor
|
HU227041B1
(en)
*
|
2003-03-24 |
2010-05-28 |
Richter Gedeon Nyrt |
Process for the synthesis of amorphous atorvastatin calcium
|
RU2337905C2
(ru)
*
|
2003-04-14 |
2008-11-10 |
Уорнер-Ламберт Компани Ллс |
Способ получения фениламида 5-(4-фторфенил)-1-[2-((2r,4r)-4-гидрокси-6-оксотетрагидропиран-2-ил)этил]-2-изопропил-4-фенил-1h-пиррол-3-карбоновой кислоты
|
JP2007516227A
(ja)
*
|
2003-05-16 |
2007-06-21 |
アンビット バイオサイエンシス コーポレーション |
ピロール化合物およびその使用
|
US20050182125A1
(en)
*
|
2003-05-16 |
2005-08-18 |
Ambit Biosciences Corporation |
Pyrrole compounds and uses thereof
|
US20040248972A1
(en)
*
|
2003-05-16 |
2004-12-09 |
Ambit Biosciences Corporation |
Compounds and uses thereof
|
US7790197B2
(en)
*
|
2003-06-09 |
2010-09-07 |
Warner-Lambert Company Llc |
Pharmaceutical compositions of atorvastatin
|
US20050271717A1
(en)
*
|
2003-06-12 |
2005-12-08 |
Alfred Berchielli |
Pharmaceutical compositions of atorvastatin
|
US20040253305A1
(en)
*
|
2003-06-12 |
2004-12-16 |
Luner Paul E. |
Pharmaceutical compositions of atorvastatin
|
US7655692B2
(en)
|
2003-06-12 |
2010-02-02 |
Pfizer Inc. |
Process for forming amorphous atorvastatin
|
KR101113163B1
(ko)
*
|
2003-07-25 |
2012-02-17 |
브래드포드 파마 리미티드 |
스타틴, 특히 아토르바스타틴의 제조에 유용한 중간체화합물 및 그 제조방법
|
CN1839114A
(zh)
|
2003-08-21 |
2006-09-27 |
默克弗罗斯特加拿大有限公司 |
组织蛋白酶半胱氨酸蛋白酶抑制剂
|
RU2315755C2
(ru)
*
|
2003-09-17 |
2008-01-27 |
Уорнер-Ламберт Компани Ллс |
Кристаллические формы [r-(r*,r*)]-2-(4-фторфенил)-бета, дельта-дигидрокси-5-(1-метилэтил)-3-фенил-4-[(фениламино)карбонил]-1н-пиррол-1-гептановой кислоты
|
US8227434B1
(en)
|
2003-11-04 |
2012-07-24 |
H. Lee Moffitt Cancer Center & Research Institute, Inc. |
Materials and methods for treating oncological disorders
|
EP1689383B1
(en)
|
2003-11-19 |
2012-10-31 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing thyromimetics
|
CA2547573A1
(en)
*
|
2003-12-05 |
2005-06-23 |
Warner-Lambert Company Llc |
N-alkyl pyrroles as hmg-coa reductase inhibitors
|
US20050152323A1
(en)
*
|
2004-01-12 |
2005-07-14 |
Vincent Bonnassieux |
Plug-in Wi-Fi access point device and system
|
CA2456430A1
(en)
*
|
2004-01-28 |
2005-07-28 |
Brantford Chemicals Inc. |
Improved process for the preparation of amorphous atorvastatin calcium
|
EP1727795B1
(en)
|
2004-03-17 |
2012-02-15 |
Ranbaxy Laboratories Limited |
Process for the production of atorvastatin calcium in amorphous form
|
MXPA06011987A
(es)
*
|
2004-04-16 |
2007-01-16 |
Pfizer Prod Inc |
Procedimiento para formar calcio de atorvastatina amorfa.
|
CA2564030C
(en)
|
2004-05-05 |
2010-06-08 |
Pfizer Products Inc. |
Salt forms of [r-(r*, r*)]-2-(4-fluorophenyl)-.beta., .delta.-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid
|
PL1771455T3
(pl)
*
|
2004-07-16 |
2016-11-30 |
|
Produkty degradacji oksydacyjnej atorwastatyny wapniowej
|
MX2007000765A
(es)
|
2004-07-20 |
2007-03-28 |
Warner Lambert Co |
Formas cristalinas de sal de calcio del acido (r-(r*, r*))-2- (4-fluorofenil)- beta,gama- dihidroxi-5- (1-metiletil)-3 -fenil-4-((fenilamino) (carbonil)-1ih -pirrol-1- heptanoico (2:1).
|
JP2008510798A
(ja)
|
2004-08-27 |
2008-04-10 |
バイオコン・リミテッド |
非晶質アトルバスタチンカルシウムのための方法
|
EP1807055A1
(en)
|
2004-10-28 |
2007-07-18 |
Warner-Lambert Company LLC |
Process for forming amorphous atorvastatin
|
CA2588216A1
(en)
*
|
2004-11-22 |
2006-05-26 |
Dexcel Pharma Technologies Ltd. |
Stable atorvastatin formulations
|
CA2589537A1
(en)
*
|
2004-12-02 |
2006-06-08 |
Stephen Craig Dyar |
Pharmaceutical compositions of amorphous atorvastatin and process for preparing same
|
EP1827421B1
(en)
|
2004-12-09 |
2017-09-27 |
Merck Sharp & Dohme Corp. |
Estrogen receptor modulators
|
CA2498978A1
(en)
|
2005-02-28 |
2006-08-28 |
Apotex Pharmachem Inc. |
An improved process for the preparation of atorvastatin and intermediates
|
CA2499047A1
(en)
*
|
2005-03-01 |
2006-09-01 |
Apotex Pharmachem Inc. |
Process for producing atorvastatin hemicalcium
|
AU2006302797B2
(en)
|
2005-03-02 |
2012-02-02 |
Merck Canada Inc. |
Composition for inhibition of cathepsin K
|
GB2424880A
(en)
*
|
2005-04-06 |
2006-10-11 |
Generics |
Crystalline forms of atorvastatin sodium, processes for their preparation and their use in inhibiting HMG-CoA reductase
|
RO200700700A8
(ro)
*
|
2005-04-08 |
2015-07-30 |
Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag |
Procedeu pentru prepararea unei noi forme cristaline polimorfe a sării de hemicalciu a atorvastatinului
|
US8362075B2
(en)
|
2005-05-17 |
2013-01-29 |
Merck Sharp & Dohme Corp. |
Cyclohexyl sulphones for treatment of cancer
|
TWI387592B
(zh)
*
|
2005-08-30 |
2013-03-01 |
Novartis Ag |
經取代之苯并咪唑及其作為與腫瘤形成相關激酶之抑制劑之方法
|
WO2007029217A1
(en)
*
|
2005-09-09 |
2007-03-15 |
Pfizer Science And Technology Ireland Limited |
Preparation of an atorvastatin intermediate
|
ATE432276T1
(de)
*
|
2005-09-09 |
2009-06-15 |
Pfizer Science & Tech Ltd |
Herstellung eines atorvastatin-zwischenprodukts
|
US20090216029A1
(en)
*
|
2005-09-16 |
2009-08-27 |
Yatendra Kumar |
Process for the production of atorvastatin calcium in amorphous form
|
CA2547216A1
(en)
|
2005-09-21 |
2007-03-21 |
Renuka D. Reddy |
Process for annealing amorphous atorvastatin
|
US8084488B2
(en)
*
|
2005-11-21 |
2011-12-27 |
Pfizer Inc. |
Forms of [R-(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid magnesium
|
KR20100023059A
(ko)
*
|
2005-12-13 |
2010-03-03 |
테바 파마슈티컬 인더스트리즈 리미티드 |
아토바스타틴 헤미칼슘의 결정형 및 이의 제조 방법
|
EP1810667A1
(en)
|
2006-01-20 |
2007-07-25 |
KRKA, tovarna zdravil, d.d., Novo mesto |
Pharmaceutical composition comprising amorphous atorvastatin
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
KR20070116963A
(ko)
*
|
2006-03-01 |
2007-12-11 |
테바 파마슈티컬 인더스트리즈 리미티드 |
아토르바스타틴 헤미 칼슘 결정형의 제조 방법
|
SI2010528T1
(en)
|
2006-04-19 |
2018-02-28 |
Novartis Ag |
6-O-substituted benzoxazole and benzothiazole compounds and procedures for inhibiting CSF-1R signaling
|
WO2008039327A2
(en)
|
2006-09-22 |
2008-04-03 |
Merck & Co., Inc. |
Method of treatment using fatty acid synthesis inhibitors
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
US20100113802A1
(en)
*
|
2006-11-02 |
2010-05-06 |
Cadila Pharmaceuticals Limited |
Process for preparing amorphous atorvastatin hemi calcium salt and its itermediate
|
PL2336120T3
(pl)
|
2007-01-10 |
2014-12-31 |
Msd Italia Srl |
Kombinacje zawierające indazole podstawione grupą amidową jako inhibitory polimerazy poli(ADP-rybozy) (PARP)
|
US7834195B2
(en)
*
|
2007-01-24 |
2010-11-16 |
Apotex Pharmachem Inc. |
Atorvastatin calcium propylene glycol solvates
|
MX2009009304A
(es)
|
2007-03-01 |
2009-11-18 |
Novartis Ag |
Inhibidores de cinasa pim y metodos para su uso.
|
US9217164B2
(en)
|
2007-03-01 |
2015-12-22 |
Basf Enzymes Llc |
Nitrilases, nucleic acids encoding them and methods for making and using them
|
CA2685967A1
(en)
|
2007-05-21 |
2008-11-21 |
Novartis Ag |
Csf-1r inhibitors, compositions, and methods of use
|
CA2690191C
(en)
|
2007-06-27 |
2015-07-28 |
Merck Sharp & Dohme Corp. |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors
|
US20110142883A1
(en)
*
|
2007-07-20 |
2011-06-16 |
Actavis Group Ptc Ehf |
Amorphous Coprecipitates of Atorvastatin Pharmaceutically Acceptable Salts
|
PT2222636E
(pt)
|
2007-12-21 |
2013-07-16 |
Ligand Pharm Inc |
Moduladores seletivos de recetores de andrógeno (sarms) e suas utilizações
|
EP2075246A1
(en)
|
2007-12-27 |
2009-07-01 |
M. J. Institute of Research |
A process for preparation of amorphous form of atorvastatin hemi-calcium salt
|
CN101429195B
(zh)
*
|
2008-11-03 |
2010-12-15 |
华东师范大学 |
一种高纯度阿托伐他汀重要合成中间体的制备方法
|
EP2373609B1
(en)
|
2008-12-19 |
2013-10-16 |
KRKA, D.D., Novo Mesto |
Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
|
EP2327682A1
(en)
|
2009-10-29 |
2011-06-01 |
KRKA, D.D., Novo Mesto |
Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
|
US8115015B2
(en)
*
|
2009-01-26 |
2012-02-14 |
Cadila Healthcare Limited |
Process for the preparation of amorphous atorvastatin calcium
|
WO2010093601A1
(en)
|
2009-02-10 |
2010-08-19 |
Metabasis Therapeutics, Inc. |
Novel sulfonic acid-containing thyromimetics, and methods for their use
|
WO2010114780A1
(en)
|
2009-04-01 |
2010-10-07 |
Merck Sharp & Dohme Corp. |
Inhibitors of akt activity
|
US8470805B2
(en)
*
|
2009-04-30 |
2013-06-25 |
Kaohsiung Medical University |
Processes for preparing piperazinium salts of KMUP and use thereof
|
PE20121172A1
(es)
|
2009-10-14 |
2012-09-05 |
Merck Sharp & Dohme |
Piperidinas sustituidas con actividad en la hdm2
|
US8999957B2
(en)
|
2010-06-24 |
2015-04-07 |
Merck Sharp & Dohme Corp. |
Heterocyclic compounds as ERK inhibitors
|
KR20120011249A
(ko)
|
2010-07-28 |
2012-02-07 |
주식회사 경보제약 |
아토바스타틴 헤미칼슘염의 신규한 결정형, 이의 수화물, 및 그의 제조방법
|
CA2805265A1
(en)
|
2010-08-02 |
2012-02-09 |
Merck Sharp & Dohme Corp. |
Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina)
|
CA2807307C
(en)
|
2010-08-17 |
2021-02-09 |
Merck Sharp & Dohme Corp. |
Rna interference mediated inhibition of hepatitis b virus (hbv) gene expression using short interfering nucleic acid (sina)
|
EP2608669B1
(en)
|
2010-08-23 |
2016-06-22 |
Merck Sharp & Dohme Corp. |
NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
|
US8946216B2
(en)
|
2010-09-01 |
2015-02-03 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as ERK inhibitors
|
US9242981B2
(en)
|
2010-09-16 |
2016-01-26 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel ERK inhibitors
|
EP2632472B1
(en)
|
2010-10-29 |
2017-12-13 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of gene expression using short interfering nucleic acids (sina)
|
TWI462739B
(zh)
|
2010-11-02 |
2014-12-01 |
Univ Kaohsiung Medical |
Sildenafil-同族物四級銨哌嗪鹽類之製備及醫療用途
|
US9351965B2
(en)
|
2010-12-21 |
2016-05-31 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as ERK inhibitors
|
EP2675440B1
(en)
|
2011-02-14 |
2020-03-25 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
IN2013MN02170A
(no)
|
2011-04-21 |
2015-06-12 |
Piramal Entpr Ltd |
|
BRPI1101952B1
(pt)
*
|
2011-04-25 |
2022-02-01 |
Universidade Estadual De Campinas - Unicamp |
Processo de obtenção de atorvastatina cálcica utilizando novos intermediários e atorvastatina assim obtida
|
CN103702982A
(zh)
|
2011-07-01 |
2014-04-02 |
中化帝斯曼制药有限公司荷兰公司 |
阿托伐他汀半钙的超细晶体
|
WO2013063214A1
(en)
|
2011-10-27 |
2013-05-02 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
DE102011119719A1
(de)
|
2011-11-30 |
2013-06-06 |
GEA CFS Bühl GmbH |
Verfahren zum Aufschneiden eines Lebensmittelriegels unter Verwendung eines Schwingungssensors
|
EP2844261B1
(en)
|
2012-05-02 |
2018-10-17 |
Sirna Therapeutics, Inc. |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
|
WO2014052563A2
(en)
|
2012-09-28 |
2014-04-03 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
MX363243B
(es)
|
2012-11-28 |
2019-03-14 |
Merck Sharp & Dohme |
Composiciones para tratar cáncer y usos de dichas composiciones.
|
BR112015013611A2
(pt)
|
2012-12-20 |
2017-11-14 |
Merck Sharp & Dohme |
composto, e, composição farmacêutica
|
EP2951180B1
(en)
|
2013-01-30 |
2018-05-02 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as hdm2 inhibitors
|
EP3041938A1
(en)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
AU2014332250B2
(en)
|
2013-10-08 |
2018-07-19 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
WO2015051479A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
US10441567B2
(en)
|
2014-01-17 |
2019-10-15 |
Ligand Pharmaceuticals Incorporated |
Methods and compositions for modulating hormone levels
|
WO2015120580A1
(en)
|
2014-02-11 |
2015-08-20 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
CN105085497B
(zh)
*
|
2015-06-26 |
2017-12-26 |
上海应用技术学院 |
多取代吡咯类他汀含氟衍生物及其用途
|
CA3001627A1
(en)
|
2015-11-06 |
2017-05-11 |
Gemphire Therapeutics, Inc. |
Treatment of mixed dyslipidemia
|
WO2019094311A1
(en)
|
2017-11-08 |
2019-05-16 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
CN108558726A
(zh)
*
|
2018-03-14 |
2018-09-21 |
湖北广济药业股份有限公司 |
一种高纯度阿托伐他汀钙的制备方法
|
US20210277009A1
(en)
|
2018-08-07 |
2021-09-09 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
WO2020033284A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
KR20220123229A
(ko)
|
2019-12-17 |
2022-09-06 |
머크 샤프 앤드 돔 엘엘씨 |
Prmt5 억제제
|
CN111362856B
(zh)
*
|
2020-04-29 |
2023-08-18 |
福建海西新药创制股份有限公司 |
一种利用微反应装置生产阿托伐他汀钙的方法
|
CN116102482A
(zh)
*
|
2022-08-17 |
2023-05-12 |
重庆普佑生物医药有限公司 |
一种阿托伐他汀钙的制备方法
|