NO923014D0 - Fremgangsmaate og preparat for syntese av bch-189 og relaterte forbindelser - Google Patents
Fremgangsmaate og preparat for syntese av bch-189 og relaterte forbindelserInfo
- Publication number
- NO923014D0 NO923014D0 NO923014A NO923014A NO923014D0 NO 923014 D0 NO923014 D0 NO 923014D0 NO 923014 A NO923014 A NO 923014A NO 923014 A NO923014 A NO 923014A NO 923014 D0 NO923014 D0 NO 923014D0
- Authority
- NO
- Norway
- Prior art keywords
- bch
- related compounds
- preparation
- synthesis
- analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Steroid Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO20083728A NO20083728L (no) | 1990-02-01 | 2008-08-28 | Analogifremgangsmate for fremstilling av et terapeutisk aktivt nukleosid |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/473,318 US5204466A (en) | 1990-02-01 | 1990-02-01 | Method and compositions for the synthesis of bch-189 and related compounds |
PCT/US1991/000685 WO1991011186A1 (en) | 1990-02-01 | 1991-01-31 | Method and compositions for the synthesis of bch-189 and related compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
NO923014L NO923014L (no) | 1992-07-30 |
NO923014D0 true NO923014D0 (no) | 1992-07-30 |
Family
ID=23879071
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO923014A NO923014D0 (no) | 1990-02-01 | 1992-07-30 | Fremgangsmaate og preparat for syntese av bch-189 og relaterte forbindelser |
NO19970386A NO313048B1 (no) | 1990-02-01 | 1997-01-29 | Fremgangsmåte for fremstilling av et terapeutisk aktivt racemisk cis-1,3-oksatiolan |
NO19970385A NO324979B1 (no) | 1990-02-01 | 1997-01-29 | Analogifremgangsmate for fremstilling av et terapeutisk aktivt nukleosid |
NO20065640A NO326249B1 (no) | 1990-02-01 | 2006-12-07 | Fremgangsmate for fremstilling av en nukleosidsammensetning omfattende et 2`,3`-dideoksy-3`-tiapyrimidinnukleosid, mellomprodukter for anvendelse i fremgangsmaten samt fremgangsmate for fremstilling av mellomprodukt |
NO2008011C NO2008011I2 (no) | 1990-02-01 | 2008-07-11 | Emtricitabin (5-fluor-1-(2R,5S)-[2-(hydroksymetyl)-1,3-oksotiolan-5-y]ytosin |
NO20083728A NO20083728L (no) | 1990-02-01 | 2008-08-28 | Analogifremgangsmate for fremstilling av et terapeutisk aktivt nukleosid |
Family Applications After (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19970386A NO313048B1 (no) | 1990-02-01 | 1997-01-29 | Fremgangsmåte for fremstilling av et terapeutisk aktivt racemisk cis-1,3-oksatiolan |
NO19970385A NO324979B1 (no) | 1990-02-01 | 1997-01-29 | Analogifremgangsmate for fremstilling av et terapeutisk aktivt nukleosid |
NO20065640A NO326249B1 (no) | 1990-02-01 | 2006-12-07 | Fremgangsmate for fremstilling av en nukleosidsammensetning omfattende et 2`,3`-dideoksy-3`-tiapyrimidinnukleosid, mellomprodukter for anvendelse i fremgangsmaten samt fremgangsmate for fremstilling av mellomprodukt |
NO2008011C NO2008011I2 (no) | 1990-02-01 | 2008-07-11 | Emtricitabin (5-fluor-1-(2R,5S)-[2-(hydroksymetyl)-1,3-oksotiolan-5-y]ytosin |
NO20083728A NO20083728L (no) | 1990-02-01 | 2008-08-28 | Analogifremgangsmate for fremstilling av et terapeutisk aktivt nukleosid |
Country Status (22)
Country | Link |
---|---|
US (8) | US5204466A (ru) |
EP (3) | EP0872237B1 (ru) |
JP (6) | JPH07618B2 (ru) |
KR (2) | KR100188357B1 (ru) |
AT (1) | ATE170750T1 (ru) |
AU (6) | AU658136C (ru) |
BG (1) | BG62236B1 (ru) |
CA (3) | CA2075189C (ru) |
DE (4) | DE69133556T2 (ru) |
DK (2) | DK0513200T4 (ru) |
ES (2) | ES2076130T5 (ru) |
FI (4) | FI114471B (ru) |
GR (1) | GR950300024T1 (ru) |
HK (1) | HK1014664A1 (ru) |
HU (4) | HU227485B1 (ru) |
LU (1) | LU91073I2 (ru) |
MC (1) | MC2233A1 (ru) |
NL (1) | NL300148I2 (ru) |
NO (6) | NO923014D0 (ru) |
RO (1) | RO108564B1 (ru) |
RU (1) | RU2125558C1 (ru) |
WO (1) | WO1991011186A1 (ru) |
Families Citing this family (150)
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US6175008B1 (en) * | 1988-04-11 | 2001-01-16 | Biochem Pharma Inc. | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties |
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US6350753B1 (en) | 1988-04-11 | 2002-02-26 | Biochem Pharma Inc. | 2-Substituted-4-substituted-1,3-dioxolanes and use thereof |
HU226137B1 (en) * | 1989-02-08 | 2008-05-28 | Shire Canada Inc | Process for preparing substituted 1,3-oxathiolanes with antiviral properties |
US5204466A (en) * | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
US6703396B1 (en) * | 1990-02-01 | 2004-03-09 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nuclesoside enantiomers |
US5728575A (en) * | 1990-02-01 | 1998-03-17 | Emory University | Method of resolution of 1,3-oxathiolane nucleoside enantiomers |
US20090239887A1 (en) * | 1990-02-01 | 2009-09-24 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers |
US6642245B1 (en) | 1990-02-01 | 2003-11-04 | Emory University | Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane |
US5276151A (en) * | 1990-02-01 | 1994-01-04 | Emory University | Method of synthesis of 1,3-dioxolane nucleosides |
GB9009861D0 (en) * | 1990-05-02 | 1990-06-27 | Glaxo Group Ltd | Chemical compounds |
US5444063A (en) * | 1990-12-05 | 1995-08-22 | Emory University | Enantiomerically pure β-D-dioxolane nucleosides with selective anti-Hepatitis B virus activity |
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GB9104740D0 (en) * | 1991-03-06 | 1991-04-17 | Wellcome Found | Antiviral nucleoside combination |
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US20050192299A1 (en) * | 1992-04-16 | 2005-09-01 | Yung-Chi Cheng | Method of treating or preventing hepatitis B virus |
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US5808040A (en) * | 1995-01-30 | 1998-09-15 | Yale University | L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides |
US6689761B1 (en) | 1995-02-01 | 2004-02-10 | Merck & Co., Inc. | Combination therapy for HIV infection |
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