NO330194B1 - Trykksatte doserte doseinhalatorer (MDI) - Google Patents
Trykksatte doserte doseinhalatorer (MDI) Download PDFInfo
- Publication number
- NO330194B1 NO330194B1 NO20012516A NO20012516A NO330194B1 NO 330194 B1 NO330194 B1 NO 330194B1 NO 20012516 A NO20012516 A NO 20012516A NO 20012516 A NO20012516 A NO 20012516A NO 330194 B1 NO330194 B1 NO 330194B1
- Authority
- NO
- Norway
- Prior art keywords
- metered dose
- dose inhaler
- pressurized metered
- inhaler according
- hfa
- Prior art date
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- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 description 1
- 229960003451 lactitol Drugs 0.000 description 1
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- 239000000845 maltitol Substances 0.000 description 1
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- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 1
- 229940035436 maltitol Drugs 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical class CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- 229960002969 oleic acid Drugs 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000008249 pharmaceutical aerosol Substances 0.000 description 1
- 239000005011 phenolic resin Substances 0.000 description 1
- 239000013034 phenoxy resin Substances 0.000 description 1
- 229920006287 phenoxy resin Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
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- 235000019204 saccharin Nutrition 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Steroid Compounds (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Measurement Of Radiation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI982559 IT1303789B1 (it) | 1998-11-25 | 1998-11-25 | "inalatori dosati pressurizzati" |
| IT1999MI001712 IT1313582B1 (it) | 1999-07-30 | 1999-07-30 | Inalatori dosati pressurizzati. |
| PCT/EP1999/009002 WO2000030608A1 (en) | 1998-11-25 | 1999-11-23 | Pressurised metered dose inhalers (mdi) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20012516D0 NO20012516D0 (no) | 2001-05-22 |
| NO20012516L NO20012516L (no) | 2001-07-23 |
| NO330194B1 true NO330194B1 (no) | 2011-03-07 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20012516A NO330194B1 (no) | 1998-11-25 | 2001-05-22 | Trykksatte doserte doseinhalatorer (MDI) |
Country Status (36)
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| US (8) | US7347199B1 (et) |
| EP (4) | EP1523975B1 (et) |
| JP (1) | JP2002530156A (et) |
| KR (1) | KR100696746B1 (et) |
| CN (1) | CN1200690C (et) |
| AR (1) | AR021391A1 (et) |
| AT (2) | ATE314838T1 (et) |
| AU (1) | AU764696C (et) |
| BG (1) | BG65596B1 (et) |
| BR (1) | BR9916868B1 (et) |
| CA (2) | CA2352484C (et) |
| CO (1) | CO5170487A1 (et) |
| CY (1) | CY1105356T1 (et) |
| CZ (1) | CZ301305B6 (et) |
| DE (3) | DE29923839U1 (et) |
| DK (1) | DK1131051T3 (et) |
| DZ (1) | DZ2947A1 (et) |
| EA (1) | EA004132B1 (et) |
| EE (1) | EE04259B1 (et) |
| EG (1) | EG25278A (et) |
| ES (1) | ES2255767T3 (et) |
| GE (1) | GEP20033129B (et) |
| HK (1) | HK1040063B (et) |
| HU (1) | HU226735B1 (et) |
| IL (3) | IL143294A0 (et) |
| MA (1) | MA26764A1 (et) |
| NO (1) | NO330194B1 (et) |
| NZ (2) | NZ527190A (et) |
| PL (2) | PL200658B1 (et) |
| SA (1) | SA99200825B1 (et) |
| SI (1) | SI1131051T1 (et) |
| SK (1) | SK285246B6 (et) |
| TN (1) | TNSN99220A1 (et) |
| TR (2) | TR200704956T2 (et) |
| TW (1) | TWI226247B (et) |
| WO (1) | WO2000030608A1 (et) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20010031244A1 (en) * | 1997-06-13 | 2001-10-18 | Chiesi Farmaceutici S.P.A. | Pharmaceutical aerosol composition |
| SE9703407D0 (sv) | 1997-09-19 | 1997-09-19 | Astra Ab | New use |
| SE9802073D0 (sv) | 1998-06-11 | 1998-06-11 | Astra Ab | New use |
| DZ2947A1 (fr) * | 1998-11-25 | 2004-03-15 | Chiesi Farma Spa | Inhalateur à compteur de dose sous pression. |
| US6739333B1 (en) | 1999-05-26 | 2004-05-25 | Boehringer Ingelheim Pharma Kg | Stainless steel canister for propellant-driven metering aerosols |
| US6315985B1 (en) | 1999-06-18 | 2001-11-13 | 3M Innovative Properties Company | C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability |
| IT1313553B1 (it) | 1999-07-23 | 2002-09-09 | Chiesi Farma Spa | Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione. |
| IT1317720B1 (it) * | 2000-01-07 | 2003-07-15 | Chiesi Farma Spa | Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani. |
| IT1317846B1 (it) * | 2000-02-22 | 2003-07-15 | Chiesi Farma Spa | Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva. |
| IT1318514B1 (it) * | 2000-05-12 | 2003-08-27 | Chiesi Farma Spa | Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari. |
| CZ303833B6 (cs) * | 2000-05-22 | 2013-05-22 | Chiesi Farmaceutici S.P.A. | Aerosolový prostredek |
| US20060257324A1 (en) * | 2000-05-22 | 2006-11-16 | Chiesi Farmaceutici S.P.A. | Pharmaceutical solution formulations for pressurised metered dose inhalers |
| DE10062712A1 (de) * | 2000-12-15 | 2002-06-20 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden |
| US20020085978A1 (en) * | 2000-11-10 | 2002-07-04 | Mina Buenafe | Degradation-resistant glucocorticosteroid formulations |
| GB0106046D0 (en) * | 2001-03-12 | 2001-05-02 | Glaxo Group Ltd | Canister |
| EP1241113A1 (en) | 2001-03-12 | 2002-09-18 | CHIESI FARMACEUTICI S.p.A. | Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein |
| DE10130371A1 (de) * | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika |
| DE60103527T2 (de) * | 2001-07-02 | 2005-06-16 | Chiesi Farmaceutici S.P.A. | Optimierte Tobramycin-Formulierung zur Aerosolbildung |
| EP1321159A1 (en) | 2001-12-21 | 2003-06-25 | CHIESI FARMACEUTICI S.p.A. | Pressurized metered dose inhaler (pMDI) actuators with laser drilled orifices |
| MXPA04008372A (es) * | 2002-03-01 | 2004-11-26 | Chiesi Farma Spa | Formulacion superfina de formoterol. |
| EP1340492A1 (en) * | 2002-03-01 | 2003-09-03 | CHIESI FARMACEUTICI S.p.A. | Aerosol formulations for pulmonary administration of medicaments having systemic effects |
| EP1415647A1 (en) * | 2002-10-23 | 2004-05-06 | CHIESI FARMACEUTICI S.p.A. | "Long-acting beta-2 agonists ultrafine formulations" |
| US20040126325A1 (en) * | 2002-03-12 | 2004-07-01 | David Lewis | Medicinal aerosol solution formulation products with improved chemical stability |
| DE10214263A1 (de) * | 2002-03-28 | 2003-10-16 | Boehringer Ingelheim Pharma | HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum |
| WO2004071488A1 (en) * | 2003-02-04 | 2004-08-26 | Chrysalis Technologies Incorporated | Perfluorocarbon and hydrofluorocarbon formulations and methods of making and using same |
| RS51663B (en) | 2003-03-20 | 2011-10-31 | Boehringer Ingelheim Pharmaceuticals Inc. | DOSAGE FORMULATION INHALATOR USING HYDRO-FLUORO-ALKAN AS PROPELLENT |
| EP1915985A1 (en) | 2003-03-20 | 2008-04-30 | Boehringer Ingelheim Pharmaceuticals Inc. | Formulation for a Metered Dose Inhaler Using Hydro-Fluoro-Alkanes as Propellants |
| GB0311701D0 (en) * | 2003-05-21 | 2003-06-25 | Karib Kemi Pharm Liited | Improved metered dose inhaler product |
| DE602004030913D1 (de) | 2003-06-24 | 2011-02-17 | Cipla Ltd | Vorrichtung zum abgeben von pharmazeutischen produkten |
| US7273603B2 (en) * | 2003-07-11 | 2007-09-25 | Boehringer Ingelheim International Gmbh | HFC solution formulations containing an anticholinergic |
| DE10345065A1 (de) * | 2003-09-26 | 2005-04-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum |
| CN1870976A (zh) * | 2003-10-20 | 2006-11-29 | 先灵公司 | 药物组合物 |
| IL177103A0 (en) * | 2004-02-27 | 2006-12-10 | Chiesi Farma Spa | Stable pharmaceutical solution formulations for pressurized metered dose inhalers |
| UA88894C2 (ru) * | 2004-02-27 | 2009-12-10 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Стабильные фармацевтические композиции в виде растворов для ингаляторов с дозатором, которые находятся под давлением |
| EP1595531A1 (en) * | 2004-05-13 | 2005-11-16 | CHIESI FARMACEUTICI S.p.A. | Stable pharmaceutical solution formulations for pressurized metered dose inhalers |
| JP5209963B2 (ja) | 2004-07-02 | 2013-06-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 噴霧剤としてｔｇ２２７ｅａ又はｔｇ１３４ａを含有するエアロゾル懸濁製剤 |
| EP1850831B1 (en) | 2005-02-25 | 2015-12-02 | CHIESI FARMACEUTICI S.p.A. | Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent |
| WO2006105401A2 (en) * | 2005-03-30 | 2006-10-05 | Schering Corporation | Medicaments and methods combining an anticholinergic, a corticosteroid, and a long acting beta agonist |
| DE102006017320A1 (de) | 2006-04-11 | 2007-10-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel |
| US8227027B2 (en) | 2007-12-07 | 2012-07-24 | Presspart Gmbh & Co. Kg | Method for applying a polymer coating to an internal surface of a container |
| JP5908884B2 (ja) | 2010-03-15 | 2016-04-26 | ヴァージニア コモンウェルス ユニヴァーシティＶｉｒｇｉｎｉａ Ｃｏｍｍｏｎｗｅａｌｔｈ Ｕｎｉｖｅｒｓｉｔｙ | 気道炎症及び粘液線毛輸送機能異常治療用のエアロゾル化したダプソン |
| BR112013001119A2 (pt) * | 2010-07-16 | 2016-05-24 | Cipla Ltd | composição farmacêutica, processo para fabricar uma composição farmacêutica, uso de r(+)budesonida e um broncodilatador, e método de profilaxia ou tratamento de uma doença respiratória, inflamatória ou obstrutiva das vias aéreas |
| TWI399202B (zh) | 2011-03-17 | 2013-06-21 | Intech Biopharm Ltd | 製備用於治療呼吸道疾病之定量噴霧吸入劑的製程方法 |
| GB201108039D0 (en) * | 2011-05-13 | 2011-06-29 | Mexichem Amanco Holding Sa | Compositions |
| CN102379846B (zh) * | 2011-10-21 | 2014-07-02 | 江苏长风药业有限公司 | 以氢氟烷烃和聚乙二醇为辅料氟替卡松丙酸酯气雾剂制剂 |
| GB201200525D0 (en) * | 2011-12-19 | 2012-02-29 | Teva Branded Pharmaceutical Prod R & D Inc | An inhalable medicament |
| CN103207032A (zh) * | 2012-01-13 | 2013-07-17 | 热敏碟公司 | 低型面温度传感器探针 |
| KR101313993B1 (ko) * | 2012-07-24 | 2013-10-01 | 한국화학연구원 | 약물 흡입 장치 |
| DE102013214601B3 (de) * | 2013-07-25 | 2014-05-22 | Aptar Radolfzell Gmbh | Gehäuse für eine Inhalationsvorrichtung und Inhalationsvorrichtung zur oralen Verabreichung eines pharmazeutischen Mediums |
| US10034866B2 (en) | 2014-06-19 | 2018-07-31 | Teva Branded Pharmaceutical Products R&D, Inc. | Inhalable medicament comprising tiotropium |
| US10610512B2 (en) * | 2014-06-26 | 2020-04-07 | Island Breeze Systems Ca, Llc | MDI related products and methods of use |
| EP4276425A3 (en) * | 2014-09-08 | 2024-03-27 | Becton, Dickinson and Company | Enhanced platen for pharmaceutical compounding |
| CN106620976B (zh) * | 2016-12-28 | 2020-01-07 | 四川普锐特医药科技有限责任公司 | 一种丙酸氟替卡松定量吸入气雾剂 |
| US10231948B2 (en) | 2017-02-27 | 2019-03-19 | Jason Ty Nguyen | Metered dose inhaler compositions, systems, and methods |
| CN112423820A (zh) * | 2018-06-13 | 2021-02-26 | 帕夫法私人有限公司 | 用于输送呼吸道药物的装置 |
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1999
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- 1999-11-23 CN CNB99813743XA patent/CN1200690C/zh not_active Expired - Lifetime
- 1999-11-23 EP EP05001105A patent/EP1523975B1/en not_active Expired - Lifetime
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