NO20063745L - Fremgangsmater, sammensetninger og apparater for dannelse av makrocykliske forbindelser - Google Patents

Fremgangsmater, sammensetninger og apparater for dannelse av makrocykliske forbindelser

Info

Publication number
NO20063745L
NO20063745L NO20063745A NO20063745A NO20063745L NO 20063745 L NO20063745 L NO 20063745L NO 20063745 A NO20063745 A NO 20063745A NO 20063745 A NO20063745 A NO 20063745A NO 20063745 L NO20063745 L NO 20063745L
Authority
NO
Norway
Prior art keywords
reaction medium
macrocyclic compound
undesirable
reaction
compositions
Prior art date
Application number
NO20063745A
Other languages
English (en)
Inventor
Thomas E Johnson
Billy T Fowler
Original Assignee
Billy T Fowler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Billy T Fowler filed Critical Billy T Fowler
Publication of NO20063745L publication Critical patent/NO20063745L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
    • C07D291/08—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D323/00—Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Oppfinnelsen vedrører fremgangsmåter, sammensetninger og apparater for fremstilling av makrosykliske forbindelser. Først tilveiebringes en eller flere reaktanter i et reaksjonsmedium som er i stand til å danne den makrosykliske forbindelse gjennom et ønsket reaksjonsspor som inkluderer minst syklisering, og som videre er i stand til å danne uønskede oligomerer gjennom et uønsket reaksjonsspor som inkluderer uønsket oligomerisering. Oligomerisering av slike reaksjoner i reaksjonsmediet moduleres for å redusere dannelse av uønskede oligomerer og/eller for å redusere separasjon av de uønskede oligomerer fra reaksjonsmediet i forhold til en tilsvarende umodulert oligomeringsreaksjon, idet utbytter av den makrosykliske forbindelse derved maksimeres. Den således dannede makrosykliske forbindelse utvinnes deretter fra reaksjonsmediet. Foretrukket separeres den makrosykliske forbindelse spontant fra reaksjonsmediet via faseseparasjon. Mer foretrukket presipiterer den makrosykliske forbindelse spontant fra reaksjonsmediet og kan derfor lett utvinnes ved enkel filtrering.
NO20063745A 2004-02-17 2006-08-22 Fremgangsmater, sammensetninger og apparater for dannelse av makrocykliske forbindelser NO20063745L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54513104P 2004-02-17 2004-02-17
US11/059,796 US7709632B2 (en) 2004-02-17 2005-02-17 Methods, compositions, and apparatuses for forming macrocyclic compounds
PCT/US2005/005028 WO2006025859A2 (en) 2004-02-17 2005-02-17 Methods, compositions, and apparatuses for forming macrocyclic compounds

Publications (1)

Publication Number Publication Date
NO20063745L true NO20063745L (no) 2006-11-17

Family

ID=36000462

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063745A NO20063745L (no) 2004-02-17 2006-08-22 Fremgangsmater, sammensetninger og apparater for dannelse av makrocykliske forbindelser

Country Status (15)

Country Link
US (3) US7709632B2 (no)
EP (1) EP1716153B1 (no)
JP (1) JP2008504225A (no)
KR (1) KR20070009574A (no)
CN (1) CN1946656B (no)
AU (1) AU2005280639A1 (no)
BR (1) BRPI0507787A (no)
CA (1) CA2557582A1 (no)
HK (1) HK1102694A1 (no)
IL (2) IL177500A (no)
MX (1) MXPA06009440A (no)
NO (1) NO20063745L (no)
NZ (1) NZ587400A (no)
RU (2) RU2428422C2 (no)
WO (1) WO2006025859A2 (no)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070009574A (ko) * 2004-02-17 2007-01-18 토마스 이. 존슨 매크로사이클릭 화합물의 형성을 위한 방법, 조성물 및장치
KR100830718B1 (ko) * 2007-01-25 2008-05-19 한국화학연구원 알킬케텐다이머의 수소화 반응에 의한 알킬 β-락톤의제조방법
CZ302046B6 (cs) * 2008-01-21 2010-09-15 Vysoká škola chemicko-technická Oligopyrrolové makrocykly substituované v meso-polohách glykosylovanými steroidy
EP2103717B1 (de) * 2008-02-29 2010-04-21 ATOTECH Deutschland GmbH Pyrophosphat-basiertes Bad zur Abscheidung von Zinn-Legierungsschichten
CN102227489B (zh) 2008-11-26 2015-04-15 埃莱文斯可更新科学公司 通过氧解反应用天然油原料制备喷气式发动机燃料的方法
ES2687776T3 (es) 2008-11-26 2018-10-29 Elevance Renewable Sciences, Inc. Métodos para producir combustible de avión a partir de materias primas de aceite natural a través de reacciones de metátesis
JP2010163382A (ja) * 2009-01-14 2010-07-29 Idemitsu Kosan Co Ltd 環状化合物の製造方法
CA2757835A1 (en) 2009-04-08 2010-10-14 Novomer, Inc. Process for beta-lactone production
CN102473773A (zh) * 2009-07-27 2012-05-23 犹他大学研究基金会 平行的同轴分子叠片阵列
BR112012007183A2 (pt) * 2009-09-30 2017-06-20 Tranzyme Pharma Inc solvato de um sal de um composto macrocíclico, forma polimórfica, processos para preparar a forma polimórfica e uma composição farmacêutica, composição farmacêutica, sal de um composto macrocíclico, e, métodos para estimular motilidade gastrintestinal, para tratar um distúrbio gastrintestinal e para tratar um indivíduo, e, kit
US8735640B2 (en) 2009-10-12 2014-05-27 Elevance Renewable Sciences, Inc. Methods of refining and producing fuel and specialty chemicals from natural oil feedstocks
US9169447B2 (en) 2009-10-12 2015-10-27 Elevance Renewable Sciences, Inc. Methods of refining natural oils, and methods of producing fuel compositions
US9222056B2 (en) 2009-10-12 2015-12-29 Elevance Renewable Sciences, Inc. Methods of refining natural oils, and methods of producing fuel compositions
US9365487B2 (en) 2009-10-12 2016-06-14 Elevance Renewable Sciences, Inc. Methods of refining and producing dibasic esters and acids from natural oil feedstocks
US9000246B2 (en) 2009-10-12 2015-04-07 Elevance Renewable Sciences, Inc. Methods of refining and producing dibasic esters and acids from natural oil feedstocks
US9382502B2 (en) 2009-10-12 2016-07-05 Elevance Renewable Sciences, Inc. Methods of refining and producing isomerized fatty acid esters and fatty acids from natural oil feedstocks
WO2011046872A2 (en) 2009-10-12 2011-04-21 Elevance Renewable Sciences, Inc. Methods of refining and producing fuel from natural oil feedstocks
US9051519B2 (en) 2009-10-12 2015-06-09 Elevance Renewable Sciences, Inc. Diene-selective hydrogenation of metathesis derived olefins and unsaturated esters
US9175231B2 (en) 2009-10-12 2015-11-03 Elevance Renewable Sciences, Inc. Methods of refining natural oils and methods of producing fuel compositions
WO2012014435A1 (ja) * 2010-07-30 2012-02-02 三菱瓦斯化学株式会社 化合物、感放射線性組成物及びレジストパターン形成方法
IL207945A0 (en) 2010-09-02 2010-12-30 Robert Jansen Method for the production of carbohydrates
JP2014527456A (ja) 2011-05-13 2014-10-16 ノボマー， インコーポレイテッド 触媒的カルボニル化用触媒および方法
CN102382116B (zh) * 2011-08-31 2013-10-16 沅江华龙催化科技有限公司 一种四芳基钴卟啉的合成工艺和设备
CN102408430B (zh) * 2011-09-07 2013-11-06 沅江华龙催化科技有限公司 取代四苯基双铁卟啉的合成工艺与专用设备
CN103987682B (zh) 2011-10-26 2017-06-16 诺沃梅尔公司 用于由环氧化物制备丙烯酸酯的工艺
US9133416B2 (en) 2011-12-22 2015-09-15 Elevance Renewable Sciences, Inc. Methods for suppressing isomerization of olefin metathesis products
US9139493B2 (en) 2011-12-22 2015-09-22 Elevance Renewable Sciences, Inc. Methods for suppressing isomerization of olefin metathesis products
US9169174B2 (en) 2011-12-22 2015-10-27 Elevance Renewable Sciences, Inc. Methods for suppressing isomerization of olefin metathesis products
BR112014019944A8 (pt) 2012-02-13 2017-07-11 Novomer Inc Método para a produção contínua de um anidrido de ácido
US9388098B2 (en) 2012-10-09 2016-07-12 Elevance Renewable Sciences, Inc. Methods of making high-weight esters, acids, and derivatives thereof
CN103539822B (zh) * 2013-09-11 2017-05-03 南开大学 一种杯状金属环蕃[Rh{9,10‑双(2‑(二苯基膦基)乙基)蒽}‑(CO)Cl]3的合成方法及其应用
US10858329B2 (en) 2014-05-05 2020-12-08 Novomer, Inc. Catalyst recycle methods
KR20170012479A (ko) 2014-05-30 2017-02-02 노보머, 인코포레이티드 화학 합성을 위한 통합된 방법
US20170225157A1 (en) 2014-07-25 2017-08-10 Novomer, Inc. Synthesis of metal complexes and uses thereof
CN105586129B (zh) * 2014-10-23 2018-05-18 中国石油化工股份有限公司 一种减磨性能优异的钠基润滑脂组合物及其制备方法
CN105586133B (zh) * 2014-10-23 2018-04-13 中国石油化工股份有限公司 一种具有优良抗氧化性能的润滑脂组合物
CN105586116B (zh) * 2014-10-23 2018-05-18 中国石油化工股份有限公司 一种减磨性能优异的膨润土润滑脂组合物及其制备方法
CN105586134B (zh) * 2014-10-23 2018-06-19 中国石油化工股份有限公司 一种减磨性能优异的钙基润滑脂组合物及其制备方法
CN105586132B (zh) * 2014-10-23 2018-03-20 中国石油化工股份有限公司 一种抗氧化性能优异的膨润土润滑脂组合物及其制备方法
CN105524698B (zh) * 2014-10-23 2018-05-18 中国石油化工股份有限公司 一种减磨性能优异的复合钡基润滑脂组合物及其制备方法
CN105586139B (zh) * 2014-10-23 2018-05-25 中国石油化工股份有限公司 一种具有优良减磨抗氧化性能的润滑脂组合物
CN105586115B (zh) * 2014-10-23 2018-05-18 中国石油化工股份有限公司 一种减磨性能优异的锂基润滑脂组合物及其制备方法
CN105567403B (zh) * 2014-10-23 2018-05-18 中国石油化工股份有限公司 减磨性能优异的复合锂钙基润滑脂组合物及其制备方法
CN104451158B (zh) * 2014-11-28 2017-02-22 北京理工大学 一种杯[4]吡咯萃取分离钕的方法
MA41513A (fr) 2015-02-13 2017-12-19 Novomer Inc Procédé de distillation pour la production d'acide acrylique
KR20170134374A (ko) 2015-02-13 2017-12-06 노보머, 인코포레이티드 연속 카보닐화 방법
MA41510A (fr) 2015-02-13 2017-12-19 Novomer Inc Procédé de production d'acide acrylique
MA41514A (fr) 2015-02-13 2017-12-19 Novomer Inc Procédés intégrés de synthèse chimique
CN105924461B (zh) * 2016-04-28 2018-11-27 中国科学院上海高等研究院 一种硼辅助冠醚化合物及其制备方法和应用
US11807664B2 (en) 2017-05-12 2023-11-07 Chugai Seiyaku Kabushiki Kaisha Method for producing cyclic organic compound
WO2019026883A1 (ja) * 2017-07-31 2019-02-07 住友化学株式会社 大環状化合物の製造方法
KR20200124556A (ko) 2019-04-24 2020-11-03 삼성전자주식회사 펠리클 조립체의 제조 방법 및 포토마스크 조립체의 제조 방법
US11565995B2 (en) * 2020-04-17 2023-01-31 The Research Foundation For The State University Of New York Methods of forming imines, imine-related and imine-derived compounds using green solvents
CN112159651B (zh) * 2020-10-30 2022-11-18 四川川庆井下科技有限公司 一种多功能稠化剂及其制备方法

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980453A (en) 1986-07-21 1990-12-25 General Electric Company Macrocyclic oligomers containing spiro(bis)indane moietes
EP0282455A3 (de) 1987-03-12 1990-10-31 Gesellschaft für Biotechnologische Forschung mbH (GBF) Verfahren zur Herstellung einer macrocyclischen Verbindung
US5214158A (en) 1991-06-03 1993-05-25 General Electric Company Method for preparation of macrocyclic poly(alkylene dicarboxylate) oligomers
US5206362A (en) * 1992-02-19 1993-04-27 Texaco Chemical Company Two-step method for preparing cyclic ureas
US5208362A (en) * 1992-02-27 1993-05-04 Ethyl Corporation Process for stabilizing organophosphorus compounds
US5817830A (en) 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
US5231161A (en) 1992-10-22 1993-07-27 General Electric Company Method for preparation of macrocyclic poly(alkylene dicarboxylate) oligomers from bis(hydroxyalkyl) dicarboxylates
US5405957A (en) 1992-10-30 1995-04-11 The University Of British Columbia Wavelength-specific photosensitive compounds and expanded porphyrin-like compounds and methods of use
US6310180B1 (en) 1993-06-21 2001-10-30 Vanderbilt University Method for synthesis of proteins
US5357029A (en) * 1993-06-24 1994-10-18 General Electric Co. Macrocyclic polyimide oligomers and method for their preparation
US5587451A (en) 1993-11-26 1996-12-24 The Dow Chemical Company Process for preparing polyazamacrocycles
US5948693A (en) 1994-09-01 1999-09-07 Wisconsin Alumni Research Foundation Solid phase synthesis of immunosuppressive agents
PT854874E (pt) * 1994-11-10 2003-07-31 Pfizer Compostos de lactona macrociclica e seu processo de producao
US5936100A (en) 1996-12-16 1999-08-10 Studiengesellschaft Kohle Mbh Synthesis of functionalized macrocycles by ring closing metathesis
US6080826A (en) 1997-01-06 2000-06-27 California Institute Of Technology Template-directed ring-closing metathesis and ring-opening metathesis polymerization of functionalized dienes
AUPO830697A0 (en) 1997-07-30 1997-08-21 Commonwealth Scientific And Industrial Research Organisation Aqueous polyimide process
IT1295398B1 (it) 1997-09-24 1999-05-12 Univ Roma Composti macrociclici di tipo porfirazinico e loro derivati metallici e procedimento per la loro preparazione
DE19809543A1 (de) 1998-03-05 1999-09-09 Clariant Gmbh Verfahren zur Herstellung von makropolycyclischen Polymaninen
JP4034426B2 (ja) * 1998-06-26 2008-01-16 オリヱント化学工業株式会社 カリックス（８）アレーン誘導体の製造方法
JP2000053675A (ja) 1998-08-11 2000-02-22 Takasago Internatl Corp 大環状ラクトン化合物、その製造法及び該化合物を含有する香料組成物
JP2000191574A (ja) * 1998-12-28 2000-07-11 Tokuyama Corp ｐ―メチルカリックス［７］アレ―ンの製造方法
US6072054A (en) 1999-01-20 2000-06-06 University Of Winnipeg Cyclic aryl ethers, thioethers, and amines and method preparation
DE19907904A1 (de) 1999-02-24 2000-08-31 Clariant Gmbh Verfahren zur Herstellung von [1,1':4',1"]-Terphenylverbindungen
WO2000052012A2 (en) 1999-03-05 2000-09-08 Emory University A method for synthesizing porphyrin compounds
US6998272B2 (en) 1999-12-10 2006-02-14 Prometic Biosciences, Ltd. Macrocyclic compounds and their use
CA2400979A1 (en) 2000-02-21 2001-08-23 Takeda Chemical Industries, Ltd. Process for producing cyclic compound
US6610351B2 (en) * 2000-04-12 2003-08-26 Quantag Systems, Inc. Raman-active taggants and their recognition
US6310330B1 (en) * 2000-04-12 2001-10-30 Transport International Pool, Inc. HVAC heater power and control circuit
AU2001269760A1 (en) 2000-06-09 2001-12-24 University Of Kentucky Research Foundation Bicyclic terpenes and synthesis thereof
JP3385468B2 (ja) 2000-06-12 2003-03-10 科学技術振興事業団 新規な拡張ポルフィリン及び拡張ポルフィリンの合成法
JP2004507599A (ja) 2000-09-01 2004-03-11 サイクリクス　コーポレイション 線形ポリエステルを、大環状オリゴエステル組成物および大環状オリゴエステルに変換する方法
US6462192B2 (en) 2001-01-23 2002-10-08 Miravant Pharmaceuticals, Inc. Processes for large scale production of tetrapyrroles
US6849730B2 (en) 2001-09-25 2005-02-01 North Carolina State University Methods of making porphyrins and related compounds with Lewis acids
FR2830253B1 (fr) 2001-09-28 2005-02-04 Air Liquide Nouveau procede de preparation de macrocycles azotes c-fonctionnalises et nouveaux intermediaires obtenus
US6712972B2 (en) 2002-03-28 2004-03-30 Council Of Scientific And Industrial Research Method for the synthesis and evaluation of porphyrins, calix (4) pyrroles and allied macrocycles
US6946533B2 (en) 2002-08-01 2005-09-20 California Institute Of Technology Synthesis of macrocyclic polymers by ring insertion polymerization of cyclic olefin monomers
KR20070009574A (ko) * 2004-02-17 2007-01-18 토마스 이. 존슨 매크로사이클릭 화합물의 형성을 위한 방법, 조성물 및장치

Also Published As

Publication number Publication date
CN1946656A (zh) 2007-04-11
IL207967A0 (en) 2011-08-01
NZ587400A (en) 2012-03-30
KR20070009574A (ko) 2007-01-18
EP1716153A2 (en) 2006-11-02
IL177500A (en) 2011-05-31
RU2428422C2 (ru) 2011-09-10
HK1102694A1 (en) 2007-11-30
AU2005280639A1 (en) 2006-03-09
JP2008504225A (ja) 2008-02-14
RU2006133296A (ru) 2008-03-27
WO2006025859A2 (en) 2006-03-09
US20120157658A1 (en) 2012-06-21
MXPA06009440A (es) 2007-03-15
EP1716153B1 (en) 2013-10-09
US7709632B2 (en) 2010-05-04
BRPI0507787A (pt) 2007-07-17
IL177500A0 (en) 2006-12-10
CN1946656B (zh) 2011-08-24
WO2006025859A3 (en) 2006-11-23
CA2557582A1 (en) 2006-03-09
US8053571B2 (en) 2011-11-08
RU2010145604A (ru) 2012-05-20
EP1716153A4 (en) 2008-12-17
US20100216970A1 (en) 2010-08-26
US20070217965A1 (en) 2007-09-20

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