MY157429A - Trpm8 antagonists and their use in treatments - Google Patents

Trpm8 antagonists and their use in treatments

Info

Publication number
MY157429A
MY157429A MYPI2013004627A MYPI2013004627A MY157429A MY 157429 A MY157429 A MY 157429A MY PI2013004627 A MYPI2013004627 A MY PI2013004627A MY PI2013004627 A MYPI2013004627 A MY PI2013004627A MY 157429 A MY157429 A MY 157429A
Authority
MY
Malaysia
Prior art keywords
compounds
treatments
trpm8
useful
disorders
Prior art date
Application number
MYPI2013004627A
Other languages
English (en)
Inventor
Biswas Kaustav
Monenschein Holger
Thomas T Nguyen
Yuan Chester Chenguang
Zhong Wenge
Jean Jr David J St
Brown James
Jian J Chen
Gore Vijay Keshav
Harried Scott
Daniel B Horne
Matthew R Kaller
Liu Qingyian
Vu Van Ma
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MY157429A publication Critical patent/MY157429A/en

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Virology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
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MYPI2013004627A 2011-06-24 2012-06-21 Trpm8 antagonists and their use in treatments MY157429A (en)

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US (3) US8710043B2 (enExample)
EP (1) EP2723717A2 (enExample)
JP (1) JP2014527511A (enExample)
KR (1) KR20140045507A (enExample)
CN (1) CN103906733A (enExample)
AP (1) AP2013007331A0 (enExample)
AR (1) AR086750A1 (enExample)
AU (1) AU2012272895B2 (enExample)
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CR (1) CR20140037A (enExample)
EA (1) EA201490152A1 (enExample)
MA (1) MA35271B1 (enExample)
MX (1) MX2013015274A (enExample)
MY (1) MY157429A (enExample)
PE (1) PE20140868A1 (enExample)
PH (1) PH12013502611A1 (enExample)
TN (1) TN2013000529A1 (enExample)
TW (2) TW201429948A (enExample)
UY (1) UY34160A (enExample)
WO (1) WO2012177893A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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US20140171406A1 (en) 2014-06-19
CO6852073A2 (es) 2014-01-30
CN103906733A (zh) 2014-07-02
WO2012177893A2 (en) 2012-12-27
US20130157996A1 (en) 2013-06-20
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PE20140868A1 (es) 2014-07-18
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CA2839699A1 (en) 2012-12-27
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