CO5261501A1 - Derivados de acido pirazol-propionico y sus composiciones farmaceuticas - Google Patents
Derivados de acido pirazol-propionico y sus composiciones farmaceuticasInfo
- Publication number
- CO5261501A1 CO5261501A1 CO00085306A CO00085306A CO5261501A1 CO 5261501 A1 CO5261501 A1 CO 5261501A1 CO 00085306 A CO00085306 A CO 00085306A CO 00085306 A CO00085306 A CO 00085306A CO 5261501 A1 CO5261501 A1 CO 5261501A1
- Authority
- CO
- Colombia
- Prior art keywords
- group
- substituted
- atom
- hydrogen atom
- formula
- Prior art date
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- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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Abstract
un compuesto de la fórmula:<EMI FILE="00085306_1" ID="1" IMF=JPEG >Donde R1 representa un grupo de hidrocarburos que puede estar sustituido o un grupo heterocíclico que puede estar sustituido;X. representa un enlace, un átomo de oxígeno, un átomo de azufre, o un grupo de la fórmula: -CO-, -CS-, -CR4(OR5)- o -NR6-, donde R4 y R6 representan cada uno un átomo de hidrógeno o un grupo de hidrocarburos que puede estar sustituido, R5 representa un átomo de hidrógeno o un grupo de protección para un grupo hidroxilo,m representa un número entero de 0 a 3,Y representa un átomo de oxígeno, un átomo de azufre, o un grupo de la fórmula: -SO-, -SO2-, -NR7-, -CONR7- o- NR7CO-, donde R7 representa un átomo de hidrógeno o un grupo de hidrocarburos que puede estar sustituido,el anillo A representa un anillo aromático que puede tener además 1 a 3 sustituyentes;n representa un número entero de 1 a 8,el anillo B representa un heteroanillo de 5 miembros que contiene nitrógeno puede estar sustituido además por un grupo alquilo;X1 representa un enlace, un átomo de oxígeno, un átomo de azufre, o un grupo de la fórmula: -SO-, -SO2-, -O-SO2, o - NR16-, donde R16 representa un átomo de hidrógeno o un grupo de hidrocarburos que puede estar sustituido;R2 representa un átomo de hidrógeno, un grupo de hidrocarburos que puede estar sustituido o un grupo heterocíclico que puede estar sustituido;W representa un enlace o un residuo de hidrocarburo divalente que tiene 1 a 20 átomos de carbono;R3 representa un grupo de la fórmula: -OR8 (R8 representa un átomo de hidrógeno o un grupo de hidrocarburos que puede estar sustituido) o -NR9Rl0 (R9 y Rl0, ya sean idénticos o no, representa cada uno un átomo de hidrógeno, un grupo de hidrocarburos que puede estar sustituido, un grupo heterocíclico que puede estar sustituido, o un grupo acilo que puede estar sustituido; R9 y R10 pueden enlazarse entre sí para formar un anillo); ... SOLICITUDES DE PATENTES DE INVENCIÓNORDENADAS PUBLICAR EN DICIEMBRE DE 2002 IMPORTANTESOLICITUDES DE PATENTE DE INVENCIÓN: a partir de la fecha de publicación de esta gaceta el solicitante cuenta con un plazo de seis (6) meses para pedir que se practique el examen de patentabilidad de la solicitud, anexando el recibo de pago de la tasa correspondiente a tal fin. De no procederse así la solicitud caerá en abandono (Art. 44 de la Decisión 486).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP32031799 | 1999-11-10 | ||
JP35223799 | 1999-12-10 |
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CO5261501A1 true CO5261501A1 (es) | 2003-03-31 |
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ID=26570043
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CO00085306A CO5261501A1 (es) | 1999-11-10 | 2000-11-09 | Derivados de acido pirazol-propionico y sus composiciones farmaceuticas |
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Country | Link |
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US (1) | US7179823B1 (es) |
EP (2) | EP1457490A1 (es) |
JP (2) | JP3723071B2 (es) |
KR (1) | KR100518142B1 (es) |
CN (1) | CN1260227C (es) |
AR (1) | AR026414A1 (es) |
AT (1) | ATE271049T1 (es) |
AU (1) | AU780948C (es) |
BR (1) | BR0015466A (es) |
CA (1) | CA2390923A1 (es) |
CO (1) | CO5261501A1 (es) |
CZ (1) | CZ20021604A3 (es) |
DE (1) | DE60012213T2 (es) |
DK (1) | DK1228067T3 (es) |
ES (1) | ES2225252T3 (es) |
HK (1) | HK1045991B (es) |
HU (1) | HUP0203165A3 (es) |
IL (1) | IL149493A0 (es) |
MX (1) | MXPA02004647A (es) |
MY (1) | MY141468A (es) |
NO (1) | NO20022108L (es) |
NZ (1) | NZ519238A (es) |
PE (1) | PE20011021A1 (es) |
PL (1) | PL356487A1 (es) |
PT (1) | PT1228067E (es) |
RU (1) | RU2252939C2 (es) |
SI (1) | SI1228067T1 (es) |
SK (1) | SK6432002A3 (es) |
TR (1) | TR200402512T4 (es) |
WO (1) | WO2001038325A1 (es) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60139025D1 (de) * | 2000-12-28 | 2009-07-30 | Takeda Pharmaceutical | Alkansäurederivate, verfahren zu deren herstellung und deren verwendung |
EP1394154A4 (en) | 2001-03-23 | 2005-05-18 | Takeda Pharmaceutical | HETEROCYCLIC DERIVATIVE WITH FIVE MEMBERS OF ALKANOIC ACID |
JP4590159B2 (ja) | 2001-04-04 | 2010-12-01 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | グルコース再吸収阻害剤およびpparモジュレーターを含んで成る併用療法 |
US6838442B2 (en) * | 2001-04-04 | 2005-01-04 | Ortho-Mcneil Pharmaceutical, Inc. | Combination therapy comprising glucose reabsorption inhibitors and retinoid-X receptor modulators |
TWI311133B (en) | 2001-04-20 | 2009-06-21 | Eisai R&D Man Co Ltd | Carboxylic acid derivativeand the salt thereof |
US20040077689A1 (en) * | 2001-04-25 | 2004-04-22 | Yasuo Sugiyama | Abc expression promoters |
US7105556B2 (en) | 2001-05-30 | 2006-09-12 | Bristol-Myers Squibb Company | Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method |
US6967212B2 (en) * | 2001-05-30 | 2005-11-22 | Bristol-Myers Squibb Company | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method |
US20030092736A1 (en) * | 2001-05-30 | 2003-05-15 | Cheng Peter T. | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method |
JPWO2002098840A1 (ja) | 2001-06-04 | 2004-09-16 | エーザイ株式会社 | カルボン酸誘導体及びその塩もしくはそのエステルからなる医薬 |
WO2003000685A1 (en) * | 2001-06-20 | 2003-01-03 | Takeda Chemical Industries, Ltd. | 5-membered heterocycle derivatives |
JPWO2003016265A1 (ja) | 2001-08-17 | 2004-12-02 | エーザイ株式会社 | 環状化合物およびpparアゴニスト |
EP1445254A4 (en) * | 2001-11-13 | 2005-05-04 | Takeda Pharmaceutical | METHOD FOR PRODUCING PYRAZOL COMPOUNDS |
EP1470137B1 (en) * | 2002-01-18 | 2009-09-02 | Merck & Co., Inc. | Edg receptor agonists |
US6716842B2 (en) | 2002-04-05 | 2004-04-06 | Warner-Lambert Company, Llc | Antidiabetic agents |
CA2487315A1 (en) * | 2002-05-24 | 2003-12-04 | Takeda Pharmaceutical Company Limited | 1,2-azole derivatives with hypoglycemic and hypolipidemic activity |
JP2004277397A (ja) * | 2002-05-24 | 2004-10-07 | Takeda Chem Ind Ltd | 1,2−アゾール誘導体 |
PL374860A1 (en) | 2002-07-09 | 2005-11-14 | Bristol-Myers Squibb Company | Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method |
ES2380319T3 (es) | 2002-07-09 | 2012-05-10 | Bristol-Myers Squibb Company | Derivados heterocíclicos sustituidos útiles como agentes antidiabéticos y anti-obesidad y procedimiento |
AU2003262023A1 (en) * | 2002-09-10 | 2004-04-30 | Takeda Pharmaceutical Company Limited | Five-membered heterocyclic compounds |
JP2004123732A (ja) * | 2002-09-10 | 2004-04-22 | Takeda Chem Ind Ltd | 5員複素環化合物 |
WO2004041266A1 (ja) | 2002-11-08 | 2004-05-21 | Takeda Pharmaceutical Company Limited | 受容体機能調節剤 |
AU2003284479A1 (en) * | 2002-11-28 | 2004-06-18 | Sumitomo Pharmaceuticals Co., Ltd. | Novel heteroaryl derivative |
SI1569907T1 (sl) * | 2002-12-13 | 2016-06-30 | Ym Biosciences Australia Pty Ltd | Na nikotinamidu osnovani kinazni inhibitorji |
AU2004210127B2 (en) * | 2003-01-27 | 2009-10-01 | Merck Sharp & Dohme Corp. | Substituted pyrazoles, compositions containing such compounds and methods of use |
TW200526588A (en) * | 2003-11-17 | 2005-08-16 | Smithkline Beecham Corp | Chemical compounds |
US7517910B2 (en) | 2004-03-30 | 2009-04-14 | Takeda Pharmaceutical Company Limited | Alkoxyphenylpropanoic acid derivatives |
ES2501240T3 (es) | 2004-03-31 | 2014-10-01 | Nippon Soda Co., Ltd. | Compuesto de amina cíclica y agente de control de plagas |
WO2005099759A1 (ja) * | 2004-04-16 | 2005-10-27 | Institute Of Medicinal Molecular Design. Inc. | 動脈硬化症の予防及び/又は治療のための医薬 |
PT1756064E (pt) * | 2004-06-04 | 2008-07-22 | Merck & Co Inc | Derivados de pirazole, composições contendo tais compostos e métodos de utilização |
EP1760071A4 (en) * | 2004-06-23 | 2008-03-05 | Ono Pharmaceutical Co | COMPOUND WITH S1P RECEPTOR BINDING ABILITY AND USE THEREOF |
US7649009B2 (en) | 2004-07-07 | 2010-01-19 | Merck & Co., Inc. | Pyrazole amide derivatives, compositions containing such compounds and methods of use |
WO2006036007A2 (en) * | 2004-09-30 | 2006-04-06 | Takeda Pharmaceutical Company Limited | Modified-release preparation |
US20080051418A1 (en) * | 2004-11-26 | 2008-02-28 | Tsuyoshi Maekawa | Arylalkanoic Acid Derivative |
JPWO2006075638A1 (ja) * | 2005-01-14 | 2008-06-12 | 大日本住友製薬株式会社 | 新規ヘテロアリール誘導体 |
WO2006112549A1 (ja) | 2005-04-20 | 2006-10-26 | Takeda Pharmaceutical Company Limited | 縮合複素環化合物 |
WO2006118320A1 (ja) | 2005-04-28 | 2006-11-09 | Takeda Pharmaceutical Company Limited | チエノピリミドン化合物 |
JP5044398B2 (ja) | 2005-06-09 | 2012-10-10 | 武田薬品工業株式会社 | 固形製剤 |
JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
CN102936221B (zh) | 2005-10-06 | 2014-09-10 | 日本曹达株式会社 | 桥联环状胺化合物以及有害生物防除剂 |
JP5094416B2 (ja) | 2005-12-28 | 2012-12-12 | 武田薬品工業株式会社 | 糖尿病治療剤 |
PT2248812E (pt) | 2006-06-27 | 2014-03-12 | Takeda Pharmaceutical | Compostos cíclicos fundidos como moduladores do receptor gpr40 |
EP2058309A4 (en) | 2006-08-04 | 2010-12-22 | Takeda Pharmaceutical | CONDENSED HETEROCYCLIC COMPOUND |
US20080207654A1 (en) | 2006-11-24 | 2008-08-28 | Takeda Pharmaceutical Company Limited | Heteromonocyclic compound and use thereof |
CN104163864B (zh) | 2007-03-30 | 2017-08-01 | Ambrx公司 | 经修饰fgf‑21多肽和其用途 |
EP2149550A4 (en) | 2007-04-27 | 2010-08-11 | Takeda Pharmaceutical | HETEROCYCLIC COMPOUND WITH FIVE NITROGEN CHAINS |
US8501750B2 (en) | 2007-05-21 | 2013-08-06 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
NZ581127A (en) * | 2007-05-25 | 2012-06-29 | Abbott Gmbh & Co Kg | Heterocyclic compounds as positive modulators of metabotropic glutamate receptor 2 (mglu2 receptor) |
EP2264017A4 (en) | 2008-04-04 | 2011-07-27 | Takeda Pharmaceutical | Heterocyclic derivative and its use |
US8349886B2 (en) | 2008-04-16 | 2013-01-08 | Takeda Pharmaceutical Company Limited | Nitrogenated 5-membered heterocyclic compound |
EP2322222A4 (en) | 2008-08-07 | 2011-12-21 | Takeda Pharmaceutical | THERAPEUTIC AGENT FOR IRRITABLE COLON SYNDROME |
US8334236B2 (en) | 2009-02-03 | 2012-12-18 | Kumiai Chemical Industry Co., Ltd. | Ring-fused 2-pyridone derivatives and herbicides |
JP2010254623A (ja) | 2009-04-24 | 2010-11-11 | Takeda Chem Ind Ltd | ベンゾオキサジノン化合物の結晶 |
EP2308866A1 (de) | 2009-10-09 | 2011-04-13 | Bayer CropScience AG | Phenylpyri(mi)dinylpyrazole und ihre Verwendung als Fungizide |
JP5658284B2 (ja) * | 2010-01-27 | 2015-01-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Crth2アンタゴニストとしてのピラゾール化合物 |
CN103119043A (zh) | 2010-07-23 | 2013-05-22 | 武田药品工业株式会社 | 稠合的杂环化合物及其用途 |
US8759386B2 (en) * | 2011-01-24 | 2014-06-24 | Boehringer Ingelheim International Gmbh | Pyrazole compounds as CRTH2 antagonists |
WO2012130633A1 (en) | 2011-03-25 | 2012-10-04 | Boehringer Ingelheim International Gmbh | Pyrazole compounds as crth2 antagonists |
AR086992A1 (es) | 2011-06-20 | 2014-02-05 | Bayer Ip Gmbh | Tienilpiri(mi)dinilpirazoles |
CA2839699A1 (en) | 2011-06-24 | 2012-12-27 | Amgen Inc. | Trpm8 antagonists and their use in treatments |
MX2013015058A (es) | 2011-06-24 | 2014-01-20 | Amgen Inc | Antagonistas de melastatina 8 de potencial receptor transitorio y su uso en tratamientos. |
WO2014007228A1 (ja) | 2012-07-03 | 2014-01-09 | 小野薬品工業株式会社 | ソマトスタチン受容体作動活性を有する化合物およびその医薬用途 |
US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
CN104755465A (zh) | 2012-08-24 | 2015-07-01 | 武田药品工业株式会社 | 杂环化合物 |
CA2880326A1 (en) * | 2012-10-26 | 2014-05-01 | F. Hoffmann-La Roche Ag | 3,4-disubstituted 1 h-pyrazole and 4,5-disubstituted thiazole inhibitors of syk cap |
JP6380402B2 (ja) | 2013-09-30 | 2018-08-29 | 小野薬品工業株式会社 | ソマトスタチン受容体作動活性を有する化合物およびその医薬用途 |
JP6759100B2 (ja) * | 2013-12-30 | 2020-09-23 | ライフサイ ファーマシューティカルズ,インク. | 治療用阻害化合物 |
KR20240024362A (ko) | 2014-10-24 | 2024-02-23 | 브리스톨-마이어스 스큅 컴퍼니 | 변형된 fgf-21 폴리펩티드 및 그의 용도 |
EP3848353A1 (en) | 2014-10-24 | 2021-07-14 | Takeda Pharmaceutical Company Limited | Medicaments for the treatment of ophthalmic diseases |
JPWO2018147300A1 (ja) | 2017-02-08 | 2019-11-21 | 小野薬品工業株式会社 | ソマトスタチン受容体作動活性を有する化合物およびその医薬用途 |
KR102236356B1 (ko) | 2017-11-24 | 2021-04-05 | 주식회사 종근당 | 루푸스의 예방 또는 치료를 위한 조성물 |
KR20190099952A (ko) * | 2018-02-20 | 2019-08-28 | 주식회사 종근당 | 포도막염의 예방 또는 치료를 위한 조성물 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06779B2 (ja) * | 1985-06-10 | 1994-01-05 | 武田薬品工業株式会社 | チアゾリジオン誘導体およびそれを含んでなる医薬組成物 |
DE3600390A1 (de) | 1986-01-09 | 1987-07-16 | Hoechst Ag | Diarylalkyl-substituierte alkylamine, verfahren zu ihrer herstellung, ihre verwendung sowie sie enthaltende arzneimittel |
DE4206041A1 (de) * | 1992-02-27 | 1993-09-02 | Bayer Ag | Sulfonylbenzyl-substituierte imidazolylpropensaeurederivate |
US5591862A (en) * | 1993-06-11 | 1997-01-07 | Takeda Chemical Industries, Ltd. | Tetrazole derivatives, their production and use |
FR2707641B1 (fr) * | 1993-07-16 | 1995-08-25 | Fournier Ind & Sante | Composés de l'imidazol-5-carboxamide, leur procédé de préparation leurs intermédiaires et leur utilisation en thérapeutique. |
DE19602505A1 (de) | 1996-01-25 | 1997-07-31 | Merck Patent Gmbh | 1-(Pyrazol-4-Indol-3-yl)-Piperidine |
JPH1072434A (ja) | 1996-04-08 | 1998-03-17 | Nissan Chem Ind Ltd | 2,4−置換アニリン誘導体 |
KR100404358B1 (ko) | 1998-01-28 | 2003-11-03 | 시오노기세이야쿠가부시키가이샤 | 신규 삼환식 화합물 |
ATE272625T1 (de) | 1998-05-11 | 2004-08-15 | Takeda Chemical Industries Ltd | Oxyiminoalkansäure derivate mit hypoglykämischer und hypolipidemischer wirkung |
US6548529B1 (en) | 1999-04-05 | 2003-04-15 | Bristol-Myers Squibb Company | Heterocyclic containing biphenyl aP2 inhibitors and method |
-
2000
- 2000-11-09 ES ES00974857T patent/ES2225252T3/es not_active Expired - Lifetime
- 2000-11-09 CO CO00085306A patent/CO5261501A1/es not_active Application Discontinuation
- 2000-11-09 AR ARP000105914A patent/AR026414A1/es not_active Application Discontinuation
- 2000-11-09 NZ NZ519238A patent/NZ519238A/en unknown
- 2000-11-09 EP EP04076508A patent/EP1457490A1/en not_active Withdrawn
- 2000-11-09 IL IL14949300A patent/IL149493A0/xx unknown
- 2000-11-09 SI SI200030494T patent/SI1228067T1/xx unknown
- 2000-11-09 PT PT00974857T patent/PT1228067E/pt unknown
- 2000-11-09 RU RU2002115263/04A patent/RU2252939C2/ru not_active IP Right Cessation
- 2000-11-09 WO PCT/JP2000/007877 patent/WO2001038325A1/en active IP Right Grant
- 2000-11-09 HU HU0203165A patent/HUP0203165A3/hu unknown
- 2000-11-09 KR KR10-2002-7006055A patent/KR100518142B1/ko not_active IP Right Cessation
- 2000-11-09 DE DE60012213T patent/DE60012213T2/de not_active Expired - Lifetime
- 2000-11-09 MY MYPI20005273A patent/MY141468A/en unknown
- 2000-11-09 PE PE2000001199A patent/PE20011021A1/es not_active Application Discontinuation
- 2000-11-09 BR BR0015466-0A patent/BR0015466A/pt not_active IP Right Cessation
- 2000-11-09 PL PL00356487A patent/PL356487A1/xx not_active Application Discontinuation
- 2000-11-09 CA CA002390923A patent/CA2390923A1/en not_active Abandoned
- 2000-11-09 AU AU13031/01A patent/AU780948C/en not_active Ceased
- 2000-11-09 CN CNB008174679A patent/CN1260227C/zh not_active Expired - Fee Related
- 2000-11-09 AT AT00974857T patent/ATE271049T1/de not_active IP Right Cessation
- 2000-11-09 JP JP2000347462A patent/JP3723071B2/ja not_active Expired - Fee Related
- 2000-11-09 US US10/129,702 patent/US7179823B1/en not_active Expired - Lifetime
- 2000-11-09 TR TR2004/02512T patent/TR200402512T4/xx unknown
- 2000-11-09 EP EP00974857A patent/EP1228067B1/en not_active Expired - Lifetime
- 2000-11-09 SK SK643-2002A patent/SK6432002A3/sk unknown
- 2000-11-09 CZ CZ20021604A patent/CZ20021604A3/cs unknown
- 2000-11-09 MX MXPA02004647A patent/MXPA02004647A/es active IP Right Grant
- 2000-11-09 DK DK00974857T patent/DK1228067T3/da active
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2002
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- 2002-08-27 HK HK02106297.5A patent/HK1045991B/zh not_active IP Right Cessation
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