MX9203838A - Derivados de n-feniltiourea, proceso para su preparacion y composicion farmaceutica que los contiene - Google Patents

Derivados de n-feniltiourea, proceso para su preparacion y composicion farmaceutica que los contiene

Info

Publication number
MX9203838A
MX9203838A MX9203838A MX9203838A MX9203838A MX 9203838 A MX9203838 A MX 9203838A MX 9203838 A MX9203838 A MX 9203838A MX 9203838 A MX9203838 A MX 9203838A MX 9203838 A MX9203838 A MX 9203838A
Authority
MX
Mexico
Prior art keywords
compounds
feniltiourea
derivatives
preparation
pharmaceutical composition
Prior art date
Application number
MX9203838A
Other languages
English (en)
Inventor
Gary Mark Coppola
Robert Edson Ii Damon
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of MX9203838A publication Critical patent/MX9203838A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX9203838A 1991-07-01 1992-06-30 Derivados de n-feniltiourea, proceso para su preparacion y composicion farmaceutica que los contiene MX9203838A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72400191A 1991-07-01 1991-07-01

Publications (1)

Publication Number Publication Date
MX9203838A true MX9203838A (es) 1993-01-01

Family

ID=24908548

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203838A MX9203838A (es) 1991-07-01 1992-06-30 Derivados de n-feniltiourea, proceso para su preparacion y composicion farmaceutica que los contiene

Country Status (24)

Country Link
EP (1) EP0528146B1 (es)
JP (1) JPH05221959A (es)
KR (1) KR930002311A (es)
AT (1) ATE134364T1 (es)
AU (1) AU657141B2 (es)
CA (1) CA2072704A1 (es)
CZ (1) CZ204692A3 (es)
DE (1) DE69208408T2 (es)
DK (1) DK0528146T3 (es)
ES (1) ES2083625T3 (es)
FI (1) FI923033A (es)
GR (1) GR3019785T3 (es)
HK (1) HK73196A (es)
HU (1) HUT62558A (es)
IE (1) IE73488B1 (es)
IL (1) IL102355A0 (es)
MX (1) MX9203838A (es)
NO (1) NO922564L (es)
NZ (1) NZ243352A (es)
RO (1) RO111933B1 (es)
RU (1) RU2087467C1 (es)
SK (1) SK204692A3 (es)
TW (1) TW213448B (es)
ZA (1) ZA924823B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0938480A1 (en) * 1996-11-14 1999-09-01 American Home Products Corporation Substituted tetrahydro-1,3,5-triazin-2 1h]-thiones as anti-atherosclerotic agents
WO1998033775A1 (en) * 1997-02-03 1998-08-06 American Home Products Corporation 2-substituted-1-acyl-1,2-dihydroquinoline derivatives to increase hdl-cholesterol level
AU7498298A (en) * 1997-06-16 1999-01-04 American Home Products Corporation Elevation of hdl cholesterol by n-{2-{ (aminothioxomethyl)hydrazono} -2-arylethyl}amides
US6011053A (en) * 1997-08-01 2000-01-04 American Home Products Corporation Substituted indole-1-carbothioic acid amides as novel antiatherosclerotic agents
AU9211098A (en) * 1997-09-03 1999-03-22 American Home Products Corporation Thiourea for increasing hdl-cholesterol levels, which are useful as anti-atherosclerotic agents
AU9125998A (en) * 1997-09-03 1999-03-22 American Home Products Corporation Substituted indole-1-carbothioic acid amides as novel antiatherosclerotic agents
US6455566B1 (en) 1997-09-03 2002-09-24 Wyeth Substituted 1-aryl-3-heteroaryl-thioureas (or isothioureas) as antiatherosclerotic agents
TW415942B (en) * 1997-09-03 2000-12-21 American Home Prod Novel substituted 1-aryl-3-heteroaryl-thioureas and substituted 1-aryl-3-heteroaryl-isothioureas as antiatherosclerotic agents
DE10017881A1 (de) * 2000-04-11 2001-10-25 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
EP1303483B1 (en) * 2000-08-21 2008-04-23 Pacific Corporation Novel thiourea derivatives and the pharmaceutical compositions containing the same
JP2004506714A (ja) 2000-08-21 2004-03-04 パシフィック　コーポレーション 新規チオ尿素化合物及びこれを含有する薬学的組成物
US6472430B2 (en) 2000-10-02 2002-10-29 Hassan M. Elokdah Amino thioxomethyl amino oxyacetic acid derivatives
US20040235877A1 (en) 2001-09-14 2004-11-25 Natsuki Ishizuka Novel use of tricyclic compound
US7429593B2 (en) 2001-09-14 2008-09-30 Shionogi & Co., Ltd. Utilities of amide compounds
US8124625B2 (en) 2001-09-14 2012-02-28 Shionogi & Co., Ltd. Method of enhancing the expression of apolipoprotein AI using olefin derivatives
ES2362770B1 (es) * 2009-12-24 2012-05-22 Universidad De Sevilla Uso de compuesto n-fenil-n'-(3-metil-2-butenil)tiourea para la elaboración de medicamentos destinados al tratamiento de la encefalopatía hepática.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950537A (en) * 1973-06-29 1976-04-13 Rohm And Haas Company Gastrointestinally active thioureas
IL67417A (en) * 1982-01-26 1989-10-31 American Cyanamid Co Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them
EP0297610B1 (en) * 1987-07-02 1991-03-13 Warner-Lambert Company N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase
US5116848A (en) * 1988-03-30 1992-05-26 Warner-Lambert Company N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents
GB8908063D0 (en) * 1989-04-11 1989-05-24 Beecham Group Plc Novel compounds
JPH0395153A (ja) * 1989-06-15 1991-04-19 Mitsubishi Kasei Corp ジフェニル尿素誘導体

Also Published As

Publication number Publication date
NZ243352A (en) 1995-02-24
KR930002311A (ko) 1993-02-22
HUT62558A (en) 1993-05-28
AU1867792A (en) 1993-01-07
EP0528146A1 (en) 1993-02-24
FI923033A (fi) 1993-01-02
FI923033A0 (fi) 1992-06-30
GR3019785T3 (en) 1996-07-31
CZ204692A3 (en) 1993-01-13
NO922564L (no) 1993-01-04
ZA924823B (en) 1993-12-29
ES2083625T3 (es) 1996-04-16
JPH05221959A (ja) 1993-08-31
DE69208408T2 (de) 1996-07-18
EP0528146B1 (en) 1996-02-21
HK73196A (en) 1996-05-03
RO111933B1 (ro) 1997-03-31
HU9202047D0 (en) 1992-09-28
SK204692A3 (en) 1995-02-08
TW213448B (es) 1993-09-21
CA2072704A1 (en) 1993-01-02
DK0528146T3 (da) 1996-05-06
IL102355A0 (en) 1993-01-14
RU2087467C1 (ru) 1997-08-20
DE69208408D1 (de) 1996-03-28
IE73488B1 (en) 1997-06-04
ATE134364T1 (de) 1996-03-15
AU657141B2 (en) 1995-03-02
NO922564D0 (no) 1992-06-29
IE922132A1 (en) 1993-01-13

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