TW201429948A - Trpm8拮抗劑及其治療用途 - Google Patents
Trpm8拮抗劑及其治療用途 Download PDFInfo
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- TW201429948A TW201429948A TW103114426A TW103114426A TW201429948A TW 201429948 A TW201429948 A TW 201429948A TW 103114426 A TW103114426 A TW 103114426A TW 103114426 A TW103114426 A TW 103114426A TW 201429948 A TW201429948 A TW 201429948A
- Authority
- TW
- Taiwan
- Prior art keywords
- methyl
- phenyl
- trifluoromethyl
- pyridin
- alkyl
- Prior art date
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- 102000003610 TRPM8 Human genes 0.000 title abstract 3
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| CN113384577A (zh) * | 2016-06-13 | 2021-09-14 | 田边三菱制药株式会社 | 用于治疗或预防血管舒缩症状的组合物 |
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| US11279672B2 (en) * | 2018-04-18 | 2022-03-22 | Piramal Pharma Limited | Asymmetric synthesis of alpha-branched chiral amines |
| CN110981795B (zh) * | 2019-12-18 | 2021-02-12 | 武汉世纪久海检测技术有限公司 | 一种利用2-氰基异烟酸甲酯制备2-氨酰基异烟酸的方法 |
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| CA3221549A1 (en) * | 2021-06-08 | 2022-12-15 | Liqiang Fu | Isoindolinone compounds, and uses thereof |
| CN115108980B (zh) * | 2022-06-22 | 2023-06-16 | 济南大学 | 一种2-甲基喹啉类化合物的4号位酰基化衍生物的制备方法 |
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| CN119118901B (zh) * | 2024-09-09 | 2025-09-30 | 中国人民解放军北部战区总医院 | 一种氧吲哚类衍生物及其制备方法与在trpa1抑制剂方向的应用 |
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-
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- 2012-06-21 JP JP2014517168A patent/JP2014527511A/ja active Pending
- 2012-06-21 MY MYPI2013004627A patent/MY157429A/en unknown
- 2012-06-21 PH PH1/2013/502611A patent/PH12013502611A1/en unknown
- 2012-06-21 CN CN201280041145.5A patent/CN103906733A/zh active Pending
- 2012-06-21 AU AU2012272895A patent/AU2012272895B2/en not_active Ceased
- 2012-06-21 US US13/529,860 patent/US8710043B2/en active Active
- 2012-06-21 PE PE2013002869A patent/PE20140868A1/es not_active Application Discontinuation
- 2012-06-21 EA EA201490152A patent/EA201490152A1/ru unknown
- 2012-06-21 WO PCT/US2012/043566 patent/WO2012177893A2/en not_active Ceased
- 2012-06-21 EP EP12730134.9A patent/EP2723717A2/en not_active Withdrawn
- 2012-06-21 AP AP2013007331A patent/AP2013007331A0/xx unknown
- 2012-06-21 KR KR1020147001927A patent/KR20140045507A/ko not_active Withdrawn
- 2012-06-21 CA CA2839699A patent/CA2839699A1/en not_active Abandoned
- 2012-06-21 BR BR112013033316A patent/BR112013033316A2/pt not_active IP Right Cessation
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- 2012-06-22 TW TW103114426A patent/TW201429948A/zh unknown
- 2012-06-22 TW TW101122538A patent/TWI448454B/zh not_active IP Right Cessation
- 2012-06-25 UY UY0001034160A patent/UY34160A/es not_active Application Discontinuation
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2013
- 2013-12-23 TN TNP2013000529A patent/TN2013000529A1/fr unknown
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- 2014-01-20 MA MA36692A patent/MA35271B1/fr unknown
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- 2014-02-24 US US14/187,732 patent/US20140171406A1/en not_active Abandoned
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| BR112013033316A2 (pt) | 2017-01-31 |
| AU2012272895B2 (en) | 2015-01-22 |
| EA201490152A1 (ru) | 2014-05-30 |
| AP2013007331A0 (en) | 2013-12-31 |
| US20130157996A1 (en) | 2013-06-20 |
| PE20140868A1 (es) | 2014-07-18 |
| AR086750A1 (es) | 2014-01-22 |
| EP2723717A2 (en) | 2014-04-30 |
| TN2013000529A1 (en) | 2015-03-30 |
| AU2012272895A1 (en) | 2013-04-11 |
| MY157429A (en) | 2016-06-15 |
| TWI448454B (zh) | 2014-08-11 |
| MX2013015274A (es) | 2014-03-31 |
| CN103906733A (zh) | 2014-07-02 |
| TW201311643A (zh) | 2013-03-16 |
| US20140171406A1 (en) | 2014-06-19 |
| WO2012177893A2 (en) | 2012-12-27 |
| CL2013003715A1 (es) | 2014-06-27 |
| CA2839699A1 (en) | 2012-12-27 |
| WO2012177893A3 (en) | 2013-06-13 |
| US20140171639A1 (en) | 2014-06-19 |
| KR20140045507A (ko) | 2014-04-16 |
| US8710043B2 (en) | 2014-04-29 |
| MA35271B1 (fr) | 2014-07-03 |
| PH12013502611A1 (en) | 2014-04-28 |
| US9096527B2 (en) | 2015-08-04 |
| JP2014527511A (ja) | 2014-10-16 |
| CR20140037A (es) | 2014-03-13 |
| UY34160A (es) | 2012-08-31 |
| CO6852073A2 (es) | 2014-01-30 |
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