MY125399A - Benzimidazole compound crystal. - Google Patents
Benzimidazole compound crystal.Info
- Publication number
- MY125399A MY125399A MYPI20002497A MY125399A MY 125399 A MY125399 A MY 125399A MY PI20002497 A MYPI20002497 A MY PI20002497A MY 125399 A MY125399 A MY 125399A
- Authority
- MY
- Malaysia
- Prior art keywords
- compound crystal
- benzimidazole compound
- methyl
- benzimidazole
- crystal
- Prior art date
Links
- -1 Benzimidazole compound Chemical class 0.000 title 1
- 239000013078 crystal Substances 0.000 title 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- MJIHNNLFOKEZEW-RUZDIDTESA-N dexlansoprazole Chemical compound CC1=C(OCC(F)(F)F)C=CN=C1C[S@@](=O)C1=NC2=CC=CC=C2N1 MJIHNNLFOKEZEW-RUZDIDTESA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17150999 | 1999-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
MY125399A true MY125399A (en) | 2006-07-31 |
Family
ID=15924444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI20002497 MY125399A (en) | 1999-06-17 | 2000-06-02 | Benzimidazole compound crystal. |
Country Status (26)
Country | Link |
---|---|
US (11) | US6462058B1 (forum.php) |
EP (3) | EP2343289A1 (forum.php) |
KR (3) | KR100407847B1 (forum.php) |
CN (1) | CN1150186C (forum.php) |
AR (5) | AR031069A1 (forum.php) |
AT (1) | ATE391126T1 (forum.php) |
AU (1) | AU778820B2 (forum.php) |
BE (1) | BE2014C017I2 (forum.php) |
BR (1) | BRPI0011674B8 (forum.php) |
CA (1) | CA2375201C (forum.php) |
CY (2) | CY1110384T1 (forum.php) |
DE (1) | DE60038481T2 (forum.php) |
DK (2) | DK1977751T3 (forum.php) |
ES (2) | ES2426985T3 (forum.php) |
HU (1) | HU229067B1 (forum.php) |
IL (2) | IL145996A0 (forum.php) |
MX (1) | MXPA01012642A (forum.php) |
MY (1) | MY125399A (forum.php) |
NO (1) | NO321168B1 (forum.php) |
NZ (1) | NZ515702A (forum.php) |
PL (1) | PL201068B1 (forum.php) |
PT (2) | PT1977751E (forum.php) |
SI (1) | SI1129088T1 (forum.php) |
TW (2) | TWI289557B (forum.php) |
WO (2) | WO2000078745A2 (forum.php) |
ZA (1) | ZA200108331B (forum.php) |
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CA2701704C (en) * | 2000-05-15 | 2011-09-06 | Takeda Pharmaceutical Company Limited | Process for producing crystal |
CA2775616C (en) | 2000-08-04 | 2013-09-17 | Takeda Pharmaceutical Company Limited | Salts of benzimidazole compound and application thereof |
CA2436825C (en) * | 2000-12-01 | 2011-01-18 | Takeda Chemical Industries, Ltd. | Process for the crystallization of (r)- or (s)-lansoprazole |
DK1459737T3 (da) | 2001-10-17 | 2013-01-02 | Takeda Pharmaceutical | Granulat indeholdende syreustabilt kemisk middel i stor mængde |
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US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
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US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
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ES2675581T3 (es) | 2005-02-25 | 2018-07-11 | Takeda Pharmaceutical Company Limited | Método para producir gránulos de un compuesto de bencimidazol recubiertos |
ES2259269B1 (es) | 2005-03-03 | 2007-11-01 | Esteve Quimica, S.A. | Procedimiento para la preparacion de derivados de 2-(2-piridilmetilsulfinil)-bencimidazol opticamente activos. |
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WO2013140120A1 (en) | 2012-03-22 | 2013-09-26 | Cipla Limited | Glycerol solvate forms of (r) - 2 - [ [ [3 -methyl -4 (2,2, 2 - trifluoroethoxy) pyridin- 2 - yl] methyl] sulphinyl] - 1h - ben zimidazole |
WO2013179194A1 (en) | 2012-05-31 | 2013-12-05 | Ranbaxy Laboratories Limited | Process for the preparation of crystalline dexlansoprazole |
CN103709139B (zh) * | 2012-10-09 | 2016-12-21 | 上海汇伦生命科技有限公司 | 无水右兰索拉唑的制备方法 |
CN104177333A (zh) * | 2013-05-24 | 2014-12-03 | 四川海思科制药有限公司 | 一种理化性质稳定的(r)-2-[[[3-甲基-4-(2,2,2-三氟乙氧基)-2-吡啶基]甲基]亚磺酰基]-1h-苯并咪唑 |
CN104650035A (zh) * | 2013-11-25 | 2015-05-27 | 天津市汉康医药生物技术有限公司 | 右兰索拉唑倍半水合物化合物 |
CN103664889B (zh) * | 2013-12-19 | 2014-11-19 | 悦康药业集团有限公司 | 一种兰索拉唑化合物 |
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CN104844576B (zh) * | 2015-04-28 | 2017-03-08 | 山东罗欣药业集团股份有限公司 | 一种兰索拉唑或右旋兰索拉唑晶型化合物及其制备方法 |
CN104829594A (zh) * | 2015-05-15 | 2015-08-12 | 苗怡文 | 一种治疗胃溃疡的药物兰索拉唑化合物 |
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CN104997738A (zh) * | 2015-08-10 | 2015-10-28 | 青岛蓝盛洋医药生物科技有限责任公司 | 一种治疗胃病的药物兰索拉唑组合物干混悬剂 |
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CN108164507A (zh) * | 2016-12-07 | 2018-06-15 | 天津药物研究院有限公司 | 一种右兰索拉唑单晶及其制备方法和用途 |
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CN106866630B (zh) * | 2017-04-01 | 2018-08-07 | 上海华源医药科技发展有限公司 | 一种右兰索拉唑的制备方法 |
CN107011329A (zh) * | 2017-05-05 | 2017-08-04 | 广州大光制药有限公司 | 兰索拉唑一水合物晶型及其结晶制备方法 |
CN108794450B (zh) * | 2018-07-24 | 2022-08-19 | 浙江恒康药业股份有限公司 | 制备无定型右旋兰索拉唑的方法 |
EP4598528A1 (en) | 2022-10-04 | 2025-08-13 | Arsenil Zabirnyk | Inhibition of aortic valve calcification |
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SE504459C2 (sv) | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
GB9423968D0 (en) | 1994-11-28 | 1995-01-11 | Astra Ab | Resolution |
HRP960232A2 (en) | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
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US6043263A (en) | 1996-11-12 | 2000-03-28 | Byk Gulden Lomberg Chemische Fabrik Gmbh | (2,3-dihydrobenzofuranyl)-thiazoles as phosphodiesterase inhibitors |
TW385306B (en) * | 1996-11-14 | 2000-03-21 | Takeda Chemical Industries Ltd | Method for producing crystals of benzimidazole derivatives |
EP0941102A1 (en) * | 1996-11-22 | 1999-09-15 | The Procter & Gamble Company | Compositions for the treatment of gastrointestinal disorders containing bismuth and nsaid |
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CA2320963A1 (en) | 1998-01-30 | 1999-08-05 | Sepracor, Inc. | R-lansoprazole compositions and methods |
EP1056457A4 (en) | 1998-01-30 | 2006-10-25 | Sepracor Inc | S-LANSOPRAZOLE COMPOSITIONS AND METHODS OF USE |
AU3596199A (en) * | 1998-05-06 | 1999-11-23 | Kobenhavns Universitet | Treatment of celiac disease |
TWI289557B (en) * | 1999-06-17 | 2007-11-11 | Takeda Chemical Industries Ltd | A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole |
JP3283252B2 (ja) * | 1999-06-17 | 2002-05-20 | 武田薬品工業株式会社 | ベンズイミダゾール化合物の結晶 |
WO2001002389A1 (fr) * | 1999-06-30 | 2001-01-11 | Takeda Chemical Industries, Ltd. | Cristaux de composes benzimidazole |
CN1117747C (zh) * | 2000-06-19 | 2003-08-13 | 中国科学院成都有机化学研究所 | 光学纯兰索拉唑的制备方法 |
EP2596792A1 (en) * | 2002-10-16 | 2013-05-29 | Takeda Pharmaceutical Company Limited | Stable solid preparations |
CA2516600C (en) * | 2003-03-24 | 2011-04-05 | Eisai Co., Ltd. | Process for production of sulfoxide proton pump inhibitors in the amorphous state |
WO2006069159A2 (en) * | 2004-12-20 | 2006-06-29 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical compositions comprising amorphous benzimidazole compounds |
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