AR100473A2 - Un método para la manufactura de una preparación para administración oral - Google Patents
Un método para la manufactura de una preparación para administración oralInfo
- Publication number
- AR100473A2 AR100473A2 ARP140104252A ARP140104252A AR100473A2 AR 100473 A2 AR100473 A2 AR 100473A2 AR P140104252 A ARP140104252 A AR P140104252A AR P140104252 A ARP140104252 A AR P140104252A AR 100473 A2 AR100473 A2 AR 100473A2
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- oral administration
- methyl
- manufacture
- layer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Reivindicación 1: Un método para la manufactura de una preparación para administración oral caracterizado porque comprende: formular un compuesto cristalino (R)-2-[[[3-metil-4-(2,2,2-trifluoroetoxi)-2-piridinil]metil]sulfinil]-1H-benzimidazol o una sal del mismo y un portador farmacéuticamente aceptable en una primera composición; y subsecuentemente formar la preparación para administración oral. Reivindicación 3: Un método para la manufactura de una preparación para administración oral caracterizado porque comprende los pasos de: formular un compuesto cristalino de (R)-2-[[[3-metil-4-(2,2,2-trifluoroetoxi)-2-piridinil]metil]sulfinil]-1H-benzimidazol o una sal del mismo, producir gránulos que contienen al compuesto cristalino desde 0.01 a 100% en peso con relación a la totalidad de la composición en una capa de recubrimiento que contiene un medicamento, recubrir con una capa intermedia los gránulos, y recubrir con una capa entérica entre la capa entérica y la capa conteniendo el medicamento.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17150999 | 1999-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR100473A2 true AR100473A2 (es) | 2016-10-12 |
Family
ID=15924444
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000102917A AR031069A1 (es) | 1999-06-17 | 2000-06-14 | Cristal de un compuesto benzimidazol, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima |
ARP100104648A AR079473A2 (es) | 1999-06-17 | 2010-12-15 | Compuesto cristalino de benzimidazol composicion farmaceutica que lo comprende y metodo para la manufactura de dicha composicion |
ARP130104346A AR093609A2 (es) | 1999-06-17 | 2013-11-26 | Compuesto amorfo de benzimidazol, composicion farmaceutica que lo comprende y metodo para tratar o prevenir la ulcera gastrica |
ARP140104252A AR100473A2 (es) | 1999-06-17 | 2014-11-12 | Un método para la manufactura de una preparación para administración oral |
ARP150104310A AR103295A2 (es) | 1999-06-17 | 2015-12-28 | Compuesto cristalino de benzimidazol, composición farmacéutica que lo comprende y método para la manufactura de dicha composición |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000102917A AR031069A1 (es) | 1999-06-17 | 2000-06-14 | Cristal de un compuesto benzimidazol, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima |
ARP100104648A AR079473A2 (es) | 1999-06-17 | 2010-12-15 | Compuesto cristalino de benzimidazol composicion farmaceutica que lo comprende y metodo para la manufactura de dicha composicion |
ARP130104346A AR093609A2 (es) | 1999-06-17 | 2013-11-26 | Compuesto amorfo de benzimidazol, composicion farmaceutica que lo comprende y metodo para tratar o prevenir la ulcera gastrica |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP150104310A AR103295A2 (es) | 1999-06-17 | 2015-12-28 | Compuesto cristalino de benzimidazol, composición farmacéutica que lo comprende y método para la manufactura de dicha composición |
Country Status (27)
Country | Link |
---|---|
US (11) | US6462058B1 (es) |
EP (3) | EP1129088B1 (es) |
KR (3) | KR100514204B1 (es) |
CN (1) | CN1150186C (es) |
AR (5) | AR031069A1 (es) |
AT (1) | ATE391126T1 (es) |
AU (1) | AU778820B2 (es) |
BE (1) | BE2014C017I2 (es) |
BR (1) | BRPI0011674B8 (es) |
CA (1) | CA2375201C (es) |
CY (2) | CY1110384T1 (es) |
DE (1) | DE60038481T2 (es) |
DK (2) | DK1977751T3 (es) |
ES (2) | ES2426985T3 (es) |
HK (2) | HK1038227A1 (es) |
HU (1) | HU229067B1 (es) |
IL (2) | IL145996A0 (es) |
MX (1) | MXPA01012642A (es) |
MY (1) | MY125399A (es) |
NO (1) | NO321168B1 (es) |
NZ (1) | NZ515702A (es) |
PL (1) | PL201068B1 (es) |
PT (2) | PT1977751E (es) |
SI (1) | SI1129088T1 (es) |
TW (2) | TWI275587B (es) |
WO (2) | WO2004083200A1 (es) |
ZA (1) | ZA200108331B (es) |
Families Citing this family (95)
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DE60020967T2 (de) * | 1999-06-30 | 2006-05-04 | Takeda Pharmaceutical Co. Ltd. | Kristalle von lansoprazole |
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US7285668B2 (en) * | 2000-12-01 | 2007-10-23 | Takeda Pharmaceutical Company Limited | Process for the crystallization of (R)- or (S)-lansoprazole |
US8105626B2 (en) | 2001-10-17 | 2012-01-31 | Takeda Pharmaceutical Company Limited | Granules containing acid-unstable chemical in large amount |
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CN105399728B (zh) * | 2015-12-20 | 2017-11-28 | 寿光富康制药有限公司 | 一种适用于工业化生产的右兰索拉唑的处理方法 |
CN108164507A (zh) * | 2016-12-07 | 2018-06-15 | 天津药物研究院有限公司 | 一种右兰索拉唑单晶及其制备方法和用途 |
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CN107011329A (zh) * | 2017-05-05 | 2017-08-04 | 广州大光制药有限公司 | 兰索拉唑一水合物晶型及其结晶制备方法 |
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