HUP0203310A2 - Benzimidazolszármazékot tartalmazó stabil gyógyszerkészítmények és eljárás ezek előállítására - Google Patents

Benzimidazolszármazékot tartalmazó stabil gyógyszerkészítmények és eljárás ezek előállítására

Info

Publication number
HUP0203310A2
HUP0203310A2 HU0203310A HUP0203310A HUP0203310A2 HU P0203310 A2 HUP0203310 A2 HU P0203310A2 HU 0203310 A HU0203310 A HU 0203310A HU P0203310 A HUP0203310 A HU P0203310A HU P0203310 A2 HUP0203310 A2 HU P0203310A2
Authority
HU
Hungary
Prior art keywords
benzimidazol
production
pharmaceutical compositions
layer
inert
Prior art date
Application number
HU0203310A
Other languages
English (en)
Inventor
Benoit Schmitt
Original Assignee
Ratiopharm Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7932028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0203310(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ratiopharm Gmbh. filed Critical Ratiopharm Gmbh.
Publication of HUP0203310A2 publication Critical patent/HUP0203310A2/hu
Publication of HUP0203310A3 publication Critical patent/HUP0203310A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

A találmány benzimidazolszármazékot, különösen omperazolt vagy hasonlóvegyületet tartalmazó új gyógyszerkészítményre vonatkozik. Ekészítmények stabilak, annak ellenére, hogy nem lúgos, hanem savasvegyületeket tartalmaznak, amelyek érintkezésben vannak abenzimidazolszármazékokkal. A találmány szerinti gyógyszerkészítményekalkotórészei: (a) egy inert mag; (b) ezen a hatóanyagot tartalmazóréteg; (e) legalább egy inert réteg; és (d) egy külső réteg, amely azinert rétegre van felvíve, és egy enterális bevonatot tartalmaz. Atalálmány további tárgya eljárás a készítmények előállítására. Ó
HU0203310A 1999-12-09 2000-12-06 Stable pharmaceutical compositions comprising benzimidazol and method for the production thereof HUP0203310A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19959419A DE19959419A1 (de) 1999-12-09 1999-12-09 Stabile galenische Zubereitungen umfassend ein Benzimidazol und Verfahren zu ihrer Herstellung
PCT/EP2000/012286 WO2001041734A2 (de) 1999-12-09 2000-12-06 Stabile galenische zubereitungen umfassend ein benzimidazol und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
HUP0203310A2 true HUP0203310A2 (hu) 2003-02-28
HUP0203310A3 HUP0203310A3 (en) 2004-01-28

Family

ID=7932028

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203310A HUP0203310A3 (en) 1999-12-09 2000-12-06 Stable pharmaceutical compositions comprising benzimidazol and method for the production thereof

Country Status (20)

Country Link
US (1) US7105180B2 (hu)
EP (1) EP1235555B1 (hu)
JP (1) JP2003516342A (hu)
AT (1) ATE267005T1 (hu)
AU (1) AU776384B2 (hu)
CA (1) CA2393483C (hu)
CZ (1) CZ295266B6 (hu)
DE (2) DE19959419A1 (hu)
DK (1) DK1235555T3 (hu)
ES (1) ES2217025T3 (hu)
HK (1) HK1046364B (hu)
HU (1) HUP0203310A3 (hu)
NO (1) NO20022260L (hu)
PL (1) PL202498B1 (hu)
PT (1) PT1235555E (hu)
RU (1) RU2257885C2 (hu)
SK (1) SK284239B6 (hu)
TR (1) TR200401304T4 (hu)
WO (1) WO2001041734A2 (hu)
ZA (1) ZA200204536B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1524967B1 (en) * 2002-08-02 2008-03-12 Ratiopharm GmbH Pharmaceutical preparation containing a benzimidazole compound mixed with microcrystalline cellulose and a method for its preparation
US20050214372A1 (en) * 2004-03-03 2005-09-29 Simona Di Capua Stable pharmaceutical composition comprising an acid labile drug
US20060024362A1 (en) * 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
WO2013122554A1 (en) 2012-02-14 2013-08-22 Mahmut Bilgic Pellet formulations comprising esomeprazole
CA2910865C (en) 2014-07-15 2016-11-29 Isa Odidi Compositions and methods for reducing overdose
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2024088913A1 (en) 2022-10-20 2024-05-02 Hermes Pharma Gmbh Talc-free active ingredient coating

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB646006A (en) 1944-08-19 1950-11-15 Amalgamated Wireless Australas Improved short circuiting piston devices for waveguides
GB1190387A (en) 1966-05-24 1970-05-06 Green Cross Corp Enteric Coated Medicaments
JPS4819231B1 (hu) * 1970-03-06 1973-06-12
ZA743391B (en) 1974-05-28 1975-08-27 A Warren Therapeutic products
DE2732335C2 (de) 1976-07-27 1983-01-20 Sandoz-Patent-GmbH, 7850 Lörrach Tablette zur enteralen Verabreichung von Indolyloxyalkanolamin-Derivaten
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
DE3151196A1 (de) 1981-12-23 1983-06-30 Kurt Heinz Prof. Dr. 7800 Freiburg Bauer Verfahren zur herstellung von gut loeslichen 5-aminosalicylsaeure-arzneimittelzubereitungen
JPS58109413A (ja) 1981-12-23 1983-06-29 Eisai Co Ltd 耐衝撃性腸溶錠
JPS5920219A (ja) 1982-07-26 1984-02-01 Shin Etsu Chem Co Ltd 腸溶性コ−テイング製剤の製造方法
DE3233764C2 (de) 1982-09-11 1987-05-07 R.P. Scherer GmbH, 6930 Eberbach Verfahren zur Herstellung oraler Dosierungseinheiten
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
JPS59193831A (ja) 1983-04-18 1984-11-02 Sankyo Co Ltd 腸溶性製剤の製造法
CA1327010C (en) 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
GB2189699A (en) 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
JPH0768125B2 (ja) 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤
US5232706A (en) * 1990-12-31 1993-08-03 Esteve Quimica, S.A. Oral pharmaceutical preparation containing omeprazol
YU48263B (sh) 1991-06-17 1997-09-30 Byk Gulden Lomberg Chemische Fabrik Gmbh. Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola
ATE156707T1 (de) * 1991-06-21 1997-08-15 Ilsan Ilac Ve Hammaddeleri San Neues galenisches verfahren für omeprazol enthaltende pellets
FR2692146B1 (fr) 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
ES2094694B1 (es) * 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
CH687810A5 (de) 1995-05-24 1997-02-28 Mepha Ag Pelletformulierung mit Omeprazol.
JP3833314B2 (ja) * 1995-09-08 2006-10-11 武田薬品工業株式会社 発泡性組成物およびその製造方法
PT101826A (pt) 1996-02-06 1997-09-30 Medinfar Produtos Farmaceutico Processo para a preparacao de microgranulos contendo omeprazole
AU5179898A (en) 1996-11-06 1998-05-29 Sharmatek, Inc. Delayed delivery system for acid-sensitive drugs
IL131651A0 (en) 1997-03-13 2001-01-28 Hexal Ag A pharmaceutical formulation containing benzimidazoles with amino acid/caclodextrin combinations and a process for producing the same
GB9710800D0 (en) * 1997-05-23 1997-07-23 Cipla Limited Pharmaceutical composition and method of preparing it
DK173431B1 (da) * 1998-03-20 2000-10-23 Gea Farmaceutisk Fabrik As Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs

Also Published As

Publication number Publication date
RU2257885C2 (ru) 2005-08-10
CA2393483A1 (en) 2001-06-14
ES2217025T3 (es) 2004-11-01
DE50006531D1 (de) 2004-06-24
HK1046364A1 (en) 2003-01-10
NO20022260D0 (no) 2002-05-10
NO20022260L (no) 2002-05-10
HUP0203310A3 (en) 2004-01-28
TR200401304T4 (tr) 2004-09-21
HK1046364B (zh) 2004-10-21
PL202498B1 (pl) 2009-06-30
WO2001041734A2 (de) 2001-06-14
AU776384B2 (en) 2004-09-09
JP2003516342A (ja) 2003-05-13
US7105180B2 (en) 2006-09-12
PT1235555E (pt) 2004-09-30
DE19959419A1 (de) 2001-06-21
EP1235555A2 (de) 2002-09-04
WO2001041734A3 (de) 2001-12-06
RU2002114862A (ru) 2004-01-27
CA2393483C (en) 2009-09-15
CZ295266B6 (cs) 2005-06-15
US20030114494A1 (en) 2003-06-19
ZA200204536B (en) 2003-09-29
ATE267005T1 (de) 2004-06-15
CZ20021875A3 (cs) 2002-11-13
SK7802002A3 (en) 2003-01-09
EP1235555B1 (de) 2004-05-19
PL355664A1 (en) 2004-05-04
SK284239B6 (en) 2004-11-03
AU2672001A (en) 2001-06-18
DK1235555T3 (da) 2004-07-26

Similar Documents

Publication Publication Date Title
HUP0002364A2 (hu) Savérzékeny benzimidazolok stabilizálása aminosav-ciklodextrin kombinációkkal
HUP0101178A2 (hu) Gyomorfekély elleni 2-{[(2-piridinil)-metil]-szulfinil}-benzimidazolt tartalmazó gyógyszerkészítmény és eljárás gyógyszerkészítmény előállítására
DK1124539T3 (da) Farmaceutisk formulering der omfatter omeprazol
IS2856B (is) Lyfjablanda úr ómeprasól
AU2001230892A1 (en) Orally administered pharmaceutical formulations of benzimidazole derivatives andthe method of preparing the same
EE04800B1 (et) Oraalne manustamisvorm happes ebapüsiva toimeainetarbeks, toimeaineühik, selle valmistamismeetod ja kasutamine ning meetod oraalse manustamisvormi valmistamiseks
ATE324893T1 (de) Orale zusammensetzung zur pilzbehandlung die itraconazol enthält und herstellungsverfahren davon
WO2005092297A3 (en) A stable pharmaceutical composition comprising an acid labile drug
NO20023313D0 (no) Nye substituerte benzimidazol doseringsformer og fremgangsmåte for anvendelse av samme
FI945904A (fi) Mikrorakeina olevat mahasuojatut stabiilit omepratsolikoostumukset ja menetelmä niiden valmistamiseksi
HK1074631A1 (en) 1,2,3-substituted indolizine derivatives, inhibitors of fgfs, method for making same and pharmaceutical compositions containing same
NO20011721D0 (no) N-aralkylaminotetraliner som ligander for neuropeptid Y Y5 reseptor
FI914354A0 (fi) Menetelmä säädellysti lääkeainetta vapauttavan valmisteen valmistamiseksi
CA2470809A1 (en) 6-amino-morphinan derivatives, method of manufacturing them and their application
AU2002358676A1 (en) Hydroxyphenyl-pyrazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
HUP0203310A2 (hu) Benzimidazolszármazékot tartalmazó stabil gyógyszerkészítmények és eljárás ezek előállítására
AU6551198A (en) Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
HUP0102895A2 (hu) Ciklopentanon-dihidropiridin-származékok, alkalmazásuk gyógyszerkészítmények előállítására és a vegyületeket tartalmazó gyógyszerkészítmények
AU2002306687A1 (en) Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
HUP0400889A3 (en) Processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol and pharmaceutical compositions containing the compound
WO2004066982A8 (en) Stable oral benzimidazole compositions and processes for their preparation
HUP0204430A3 (en) Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives, the obtained new compounds and pharmaceutical compositions containing thereof
AU2003209533A1 (en) Process of manufacturing pharmaceutical composition useful for management of tuberculosis
WO2005051362A3 (en) Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating
AU2002325926A1 (en) Method for the continuous production and coating of self-adhesive compounds on the basis of SBC that includes at least one pharmaceutically active substance

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees