ATE324893T1 - Orale zusammensetzung zur pilzbehandlung die itraconazol enthält und herstellungsverfahren davon - Google Patents

Orale zusammensetzung zur pilzbehandlung die itraconazol enthält und herstellungsverfahren davon

Info

Publication number
ATE324893T1
ATE324893T1 AT00935726T AT00935726T ATE324893T1 AT E324893 T1 ATE324893 T1 AT E324893T1 AT 00935726 T AT00935726 T AT 00935726T AT 00935726 T AT00935726 T AT 00935726T AT E324893 T1 ATE324893 T1 AT E324893T1
Authority
AT
Austria
Prior art keywords
oral composition
production
treatment containing
fungal treatment
itraconazole
Prior art date
Application number
AT00935726T
Other languages
English (en)
Inventor
Jong Soo Woo
Cheoncheon-Dong
Hong Gi Yi
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Application granted granted Critical
Publication of ATE324893T1 publication Critical patent/ATE324893T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/485Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
AT00935726T 1999-06-16 2000-06-16 Orale zusammensetzung zur pilzbehandlung die itraconazol enthält und herstellungsverfahren davon ATE324893T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019990022472A KR100331529B1 (ko) 1999-06-16 1999-06-16 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법

Publications (1)

Publication Number Publication Date
ATE324893T1 true ATE324893T1 (de) 2006-06-15

Family

ID=36441999

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00935726T ATE324893T1 (de) 1999-06-16 2000-06-16 Orale zusammensetzung zur pilzbehandlung die itraconazol enthält und herstellungsverfahren davon

Country Status (18)

Country Link
US (1) US6039981A (de)
EP (1) EP1185273B1 (de)
JP (1) JP3717849B2 (de)
KR (1) KR100331529B1 (de)
CN (1) CN1170539C (de)
AT (1) ATE324893T1 (de)
AU (1) AU754300B2 (de)
CA (1) CA2376706C (de)
CZ (1) CZ292146B6 (de)
DE (1) DE60027717T2 (de)
ES (1) ES2262517T3 (de)
HU (1) HUP0201533A3 (de)
MX (1) MXPA01012739A (de)
RS (1) RS50008B (de)
RU (1) RU2216323C2 (de)
SI (1) SI20677A (de)
TR (1) TR200103681T2 (de)
WO (1) WO2000076520A1 (de)

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CA2291346A1 (en) * 1999-11-26 2001-05-26 Bernard Charles Sherman Antifungal solutions
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US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
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US9700866B2 (en) * 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
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EP1842532A3 (de) * 2001-02-06 2009-04-22 Stiefel Laboratories, Inc. Orale, schwer wasserlösliche antimykotische Formulierungen und Verfahren zu deren Herstellung
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CA2363376A1 (en) * 2001-11-16 2003-05-16 Bernard Charles Sherman Solid pharmaceutical compositions for oral administration comprising itraconazole
KR100441745B1 (ko) * 2001-11-30 2004-07-27 환인제약 주식회사 이트라코나졸의 경구투여용 조성물과 그 제조방법
US20040115266A1 (en) * 2002-02-01 2004-06-17 Namburi Ranga Raju Oral itraconazole formulations and methods of making the same
US20040266776A1 (en) 2003-06-25 2004-12-30 Gil Daniel W. Methods of preventing and reducing the severity of stress-associated conditions
EP1542728A4 (de) * 2002-07-22 2005-09-21 Nanohybrid Co Ltd Hybrid von itraconazol, cyclosporin oder carvedilol mit einem geschichteten silikat und verfahren zu seiner herstellung
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KR100663079B1 (ko) * 2004-06-24 2007-01-02 주식회사 씨티씨바이오 이트라코나졸 함유 고체분산체의 제조방법
US20060280787A1 (en) * 2005-06-14 2006-12-14 Baxter International Inc. Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof
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Also Published As

Publication number Publication date
EP1185273A4 (de) 2004-03-10
US6039981A (en) 2000-03-21
JP3717849B2 (ja) 2005-11-16
KR100331529B1 (ko) 2002-04-06
AU754300B2 (en) 2002-11-14
RS50008B (sr) 2008-09-29
CN1170539C (zh) 2004-10-13
RU2216323C2 (ru) 2003-11-20
EP1185273B1 (de) 2006-05-03
AU5114400A (en) 2001-01-02
JP2003501475A (ja) 2003-01-14
KR20010002590A (ko) 2001-01-15
EP1185273A1 (de) 2002-03-13
HUP0201533A2 (en) 2002-09-28
DE60027717T2 (de) 2007-05-10
CA2376706C (en) 2006-06-06
ES2262517T3 (es) 2006-12-01
CA2376706A1 (en) 2000-12-21
MXPA01012739A (es) 2002-07-02
CZ20014508A3 (cs) 2003-03-12
TR200103681T2 (tr) 2002-05-21
WO2000076520A1 (en) 2000-12-21
DE60027717D1 (de) 2006-06-08
YU88601A (sh) 2004-07-15
HUP0201533A3 (en) 2006-07-28
SI20677A (sl) 2002-04-30
CZ292146B6 (cs) 2003-08-13
CN1390127A (zh) 2003-01-08

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