RS50008B - Antifungalna oralna kompozicija koja sadrži itrakonazol i postupak za dobijanje iste - Google Patents

Antifungalna oralna kompozicija koja sadrži itrakonazol i postupak za dobijanje iste

Info

Publication number
RS50008B
RS50008B YUP-886/01A YUP88601A RS50008B RS 50008 B RS50008 B RS 50008B YU P88601 A YUP88601 A YU P88601A RS 50008 B RS50008 B RS 50008B
Authority
RS
Serbia
Prior art keywords
composition containing
oral composition
preparing same
itraconazole
containing itraconazole
Prior art date
Application number
YUP-886/01A
Other languages
English (en)
Inventor
Jong-Soo Woo
Hong Gi Yi
Original Assignee
Hanmi Pharm Co.Ltd.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Co.Ltd., filed Critical Hanmi Pharm Co.Ltd.,
Publication of YU88601A publication Critical patent/YU88601A/sh
Publication of RS50008B publication Critical patent/RS50008B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Abstract

Antifungalna kompozicija za oralnu primenu, naz nač ena tim e, što obuhvata stopljenu smešu itrakonazola i fosforne kiseline, i farmaceutski prihvatljiv nosač i površinski aktivno sredstvo. Antifungalna kompozicija prema zahtevu 1, naz načenatime, što se maseni odnos itrakonazola i fosforne kiseline u stopljenoj smeši kreće od 1:0.1 do 1:10. Prijava ima 3 zahteva.
YUP-886/01A 1999-06-16 2000-06-16 Antifungalna oralna kompozicija koja sadrži itrakonazol i postupak za dobijanje iste RS50008B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019990022472A KR100331529B1 (ko) 1999-06-16 1999-06-16 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법

Publications (2)

Publication Number Publication Date
YU88601A YU88601A (sh) 2004-07-15
RS50008B true RS50008B (sr) 2008-09-29

Family

ID=36441999

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-886/01A RS50008B (sr) 1999-06-16 2000-06-16 Antifungalna oralna kompozicija koja sadrži itrakonazol i postupak za dobijanje iste

Country Status (18)

Country Link
US (1) US6039981A (sr)
EP (1) EP1185273B1 (sr)
JP (1) JP3717849B2 (sr)
KR (1) KR100331529B1 (sr)
CN (1) CN1170539C (sr)
AT (1) ATE324893T1 (sr)
AU (1) AU754300B2 (sr)
CA (1) CA2376706C (sr)
CZ (1) CZ292146B6 (sr)
DE (1) DE60027717T2 (sr)
ES (1) ES2262517T3 (sr)
HU (1) HUP0201533A3 (sr)
MX (1) MXPA01012739A (sr)
RS (1) RS50008B (sr)
RU (1) RU2216323C2 (sr)
SI (1) SI20677A (sr)
TR (1) TR200103681T2 (sr)
WO (1) WO2000076520A1 (sr)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ154398A3 (cs) 1995-11-23 1998-08-12 Janssen Pharmaceutica N.V. Pevné směsi cyklodextrinů připravené vytlačováním taveniny
GB9720061D0 (en) * 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
KR100331529B1 (ko) * 1999-06-16 2002-04-06 민경윤 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법
CA2291346A1 (en) * 1999-11-26 2001-05-26 Bernard Charles Sherman Antifungal solutions
GB0015239D0 (en) * 2000-06-21 2000-08-16 Biochemie Gmbh Organic compounds
US6607784B2 (en) * 2000-12-22 2003-08-19 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US6951656B2 (en) * 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US7193084B2 (en) * 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US20040256749A1 (en) * 2000-12-22 2004-12-23 Mahesh Chaubal Process for production of essentially solvent-free small particles
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US9700866B2 (en) * 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US6884436B2 (en) * 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US6977085B2 (en) * 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
JP4376518B2 (ja) * 2000-12-22 2009-12-02 バクスター・インターナショナル・インコーポレイテッド サブミクロン粒子の懸濁物を調製する方法
KR100435141B1 (ko) * 2000-12-28 2004-06-09 한미약품 주식회사 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법
US6673373B2 (en) 2001-02-01 2004-01-06 Carlsbad Technology Inc. Antifungal formulation and the methods for manufacturing and using the same
EP1842532A3 (en) * 2001-02-06 2009-04-22 Stiefel Laboratories, Inc. Oral sparingly water-soluble antifungal formulations and methods of making the same
US6663897B2 (en) * 2001-02-06 2003-12-16 Dsm Ip Assets B.V. Oral itraconazole formulations and methods of making the same
KR100455216B1 (ko) * 2001-06-27 2004-11-09 한미약품 주식회사 난용성 항진균제의 경구투여용 조성물 및 이의 제조 방법
US8071133B2 (en) * 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
KR100425755B1 (ko) * 2001-08-27 2004-04-03 주식회사 원진신약 이트라코나졸을 함유하는 조성물 및 그 제조방법
AU2002337692B2 (en) * 2001-09-26 2007-09-13 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US20060003012A9 (en) * 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
US7112340B2 (en) 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
CA2363376A1 (en) * 2001-11-16 2003-05-16 Bernard Charles Sherman Solid pharmaceutical compositions for oral administration comprising itraconazole
KR100441745B1 (ko) * 2001-11-30 2004-07-27 환인제약 주식회사 이트라코나졸의 경구투여용 조성물과 그 제조방법
US20040115266A1 (en) * 2002-02-01 2004-06-17 Namburi Ranga Raju Oral itraconazole formulations and methods of making the same
US20040266776A1 (en) 2003-06-25 2004-12-30 Gil Daniel W. Methods of preventing and reducing the severity of stress-associated conditions
JP2005533846A (ja) * 2002-07-22 2005-11-10 ナノハイブリッド カンパニー リミテッド イトラコナゾール、シクロスポリン、またはカルベジロールと層状型珪酸塩との混成体及びその製造方法
US20050058670A1 (en) * 2003-09-09 2005-03-17 Jong-Soo Woo Oral itraconazole composition which is not affected by ingested food and process for preparing same
CA2540984C (en) 2003-10-10 2011-02-08 Lifecycle Pharma A/S A solid dosage form comprising a fibrate
BRPI0415121A (pt) * 2003-10-10 2006-11-28 Lifecycle Pharma As material particulado, forma de dosagem sólida, método para fabricar a mesma, e, uso de um material particulado ou de uma forma de dosagem sólida
US9173847B2 (en) * 2003-10-10 2015-11-03 Veloxis Pharmaceuticals A/S Tablet comprising a fibrate
US20050118265A1 (en) * 2003-11-28 2005-06-02 Anandi Krishnan Antifungal oral dosage forms and the methods for preparation
JP2005239696A (ja) * 2004-01-30 2005-09-08 Daiichi Suntory Pharma Co Ltd 無機物質を配合した医薬硬質カプセル剤
JP2007520555A (ja) * 2004-02-05 2007-07-26 バクスター・インターナショナル・インコーポレイテッド 自己安定化剤の使用により調製された分散剤
CN1294912C (zh) * 2004-03-01 2007-01-17 上海医药工业研究院 伊曲康唑盐酸盐组合物及其冻干粉针
KR20050119397A (ko) * 2004-06-16 2005-12-21 보람제약주식회사 고상용해를 이용한 난용성 약물의 가용화 방법과 이를이용한 가용화 조성물
US9492446B2 (en) * 2004-06-24 2016-11-15 Ctc Bio, Inc. Manufacturing method of solid dispersion containing itraconazole
US20060280787A1 (en) * 2005-06-14 2006-12-14 Baxter International Inc. Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof
CA2628630A1 (en) * 2005-11-15 2007-05-24 Baxter International Inc. Compositions of lipoxygenase inhibitors
MY157620A (en) * 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
GB0612809D0 (en) * 2006-06-28 2006-08-09 Univ Sunderland Formulation
US20090152176A1 (en) * 2006-12-23 2009-06-18 Baxter International Inc. Magnetic separation of fine particles from compositions
US8426467B2 (en) * 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) * 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US20080293814A1 (en) * 2007-05-22 2008-11-27 Deepak Tiwari Concentrate esmolol
GB0714670D0 (en) * 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) * 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
GB0720716D0 (en) * 2007-10-23 2007-12-05 York Pharma Plc Novel formulation
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
US10736891B2 (en) * 2016-01-07 2020-08-11 Roy MADIGAN Composition and method for treating chagas disease
CN110755369A (zh) * 2019-10-30 2020-02-07 天津市保灵动物保健品有限公司 一种伊曲康唑软膏及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE138561T1 (de) * 1992-02-12 1996-06-15 Janssen Cilag S P A Liposomale itraconazol formulierungen
AU6098094A (en) * 1993-01-27 1994-08-15 Georgetown University Methods and compositions of (2s,4r) itraconazole for treating fungal yeast and dermatophyte infections
EP0680324A4 (en) * 1993-01-27 1996-04-10 Sepracor Inc METHODS AND COMPOSITIONS USING (2R, 4S) ITRACONAZOLE.
US5750147A (en) * 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
CA2240161C (en) * 1996-05-20 2005-05-24 Janssen Pharmaceutica N.V. Antifungal compositions with improved bioavailability
KR100321617B1 (ko) * 1997-06-16 2002-07-27 동아제약 주식회사 항진균제와 유기산류의 공융혼합물 및 이를 함유하는 약학적 제제
KR100367483B1 (ko) * 1997-12-19 2003-03-26 동아제약 주식회사 당류를이용하여용해도및용해속도를증가시킨이트라코나졸경구용조성물및그제조방법
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
KR100331529B1 (ko) * 1999-06-16 2002-04-06 민경윤 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법

Also Published As

Publication number Publication date
EP1185273A1 (en) 2002-03-13
JP2003501475A (ja) 2003-01-14
TR200103681T2 (tr) 2002-05-21
HUP0201533A3 (en) 2006-07-28
MXPA01012739A (es) 2002-07-02
HUP0201533A2 (en) 2002-09-28
CZ292146B6 (cs) 2003-08-13
CN1170539C (zh) 2004-10-13
DE60027717T2 (de) 2007-05-10
CA2376706C (en) 2006-06-06
EP1185273B1 (en) 2006-05-03
ES2262517T3 (es) 2006-12-01
CZ20014508A3 (cs) 2003-03-12
ATE324893T1 (de) 2006-06-15
AU5114400A (en) 2001-01-02
US6039981A (en) 2000-03-21
CA2376706A1 (en) 2000-12-21
KR100331529B1 (ko) 2002-04-06
KR20010002590A (ko) 2001-01-15
WO2000076520A1 (en) 2000-12-21
JP3717849B2 (ja) 2005-11-16
SI20677A (sl) 2002-04-30
EP1185273A4 (en) 2004-03-10
AU754300B2 (en) 2002-11-14
CN1390127A (zh) 2003-01-08
YU88601A (sh) 2004-07-15
DE60027717D1 (de) 2006-06-08
RU2216323C2 (ru) 2003-11-20

Similar Documents

Publication Publication Date Title
RS50008B (sr) Antifungalna oralna kompozicija koja sadrži itrakonazol i postupak za dobijanje iste
AU7315301A (en) Compounds and compositions for delivering active agents
PL347671A1 (en) Compounds and compositions for delivering active agents
IL140710A0 (en) Pulmonary delivery of active agents
ATE387430T1 (de) Verbindungen und zusammensetzungen zur abgabe aktiver wirkstoffe
IL195055A0 (en) Phenoxy carboxylic acid compounds and compositions for delivering active agents
AU2001296865A1 (en) (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
EP1015008A4 (en) COMPOUNDS AND COMPOSITIONS FOR THE ADMINISTRATION OF ACTIVE SUBSTANCES
IL150986A0 (en) 1,2,3,4,- tetrahydroisoquinoline derivatives
CA2366702A1 (en) Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
BR0003158A (pt) Formulação de dosagem oral de derretimentoinstantâneo
RS50360B (sr) Farmaceutske formulacije derivata platine
NZ524138A (en) Cyanophenoxy carboxylic acid compounds and compositions for delivering active agents
MXPA03007857A (es) Compuestos y composiciones para entregar agentes activos.
WO2003035051A3 (en) The use of proton sequestering agents in drug formulations
MXPA04004567A (es) Compuestos y composiciones de fenoxi amina para adminstrar agentes activos.
AU3492100A (en) Oxadiazole compounds and compositions for delivering active agents
WO2002015959A3 (en) Compounds and compositions for delivering active agents
IL155788A (en) A highly purified ifn – β active and mannitol-containing preparation, a method to make an improved stability of ifn – β active, and a method to enhance the stability of ifn – β in biologically active formulation.
MXPA04001252A (es) Nuevos heterociclos benzo-fusionados como antagonistas de endotelina.
WO2002100338A3 (en) Compound and composition for delivering active agents
TR200401462T4 (tr) Torsemid modifikasyonu II' yi içeren dengeli bir farmasötik formülasyonu
NZ331374A (en) Phenanthridine compounds and pharmaceutical compositions thereof
JO1653B1 (en) The current benzimidazole is a therapeutically active method for preparing it