MXPA04004567A - Compuestos y composiciones de fenoxi amina para adminstrar agentes activos. - Google Patents

Compuestos y composiciones de fenoxi amina para adminstrar agentes activos.

Info

Publication number
MXPA04004567A
MXPA04004567A MXPA04004567A MXPA04004567A MXPA04004567A MX PA04004567 A MXPA04004567 A MX PA04004567A MX PA04004567 A MXPA04004567 A MX PA04004567A MX PA04004567 A MXPA04004567 A MX PA04004567A MX PA04004567 A MXPA04004567 A MX PA04004567A
Authority
MX
Mexico
Prior art keywords
compositions
active agents
amine compounds
delivering active
phenoxy amine
Prior art date
Application number
MXPA04004567A
Other languages
English (en)
Inventor
Zhu Chen
Original Assignee
Emisphere Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emisphere Tech Inc filed Critical Emisphere Tech Inc
Publication of MXPA04004567A publication Critical patent/MXPA04004567A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Abstract

Se proporcionan compuestos y composiciones de fenoxi amina para la administracion de agentes activos. Tambien se proporcionan metodos de administracion y preparacion.
MXPA04004567A 2001-11-13 2002-11-13 Compuestos y composiciones de fenoxi amina para adminstrar agentes activos. MXPA04004567A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35048801P 2001-11-13 2001-11-13
US35728802P 2002-02-15 2002-02-15
PCT/US2002/036552 WO2003045306A2 (en) 2001-11-13 2002-11-13 Phenoxy amine compounds and compositions for delivering active agents

Publications (1)

Publication Number Publication Date
MXPA04004567A true MXPA04004567A (es) 2004-09-10

Family

ID=26996636

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04004567A MXPA04004567A (es) 2001-11-13 2002-11-13 Compuestos y composiciones de fenoxi amina para adminstrar agentes activos.

Country Status (13)

Country Link
US (1) US7297794B2 (es)
EP (1) EP1453816B1 (es)
JP (1) JP4602668B2 (es)
CN (1) CN1596248B (es)
AU (1) AU2002360387B2 (es)
BR (1) BR0214199A (es)
CA (1) CA2465641C (es)
ES (1) ES2431630T3 (es)
HK (1) HK1069383A1 (es)
MX (1) MXPA04004567A (es)
NZ (1) NZ532597A (es)
WO (1) WO2003045306A2 (es)
ZA (1) ZA200403572B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003045306A2 (en) 2001-11-13 2003-06-05 Emisphere Technologies, Inc. Phenoxy amine compounds and compositions for delivering active agents
RU2332229C2 (ru) 2002-02-20 2008-08-27 Эмисфире Текнолоджис Инк. Способ введения молекул glp-1
US20040076587A1 (en) * 2002-06-19 2004-04-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical composition for intranasal administration containing a CGRP antagonist
EP1539959A2 (en) * 2002-09-18 2005-06-15 Centre Hospitalier de l'Université de Montréal (CHUM) Ghrh analogues
WO2005115406A2 (en) * 2004-04-16 2005-12-08 Emisphere Technologies, Inc. 8-(2-hydroxyphenoxy)octyldiethanolamine and salts thereof for delivery of active agents
CA2565188C (en) 2004-05-14 2014-03-04 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
ES2586423T3 (es) 2004-05-14 2016-10-14 Emisphere Technologies, Inc. Compuestos de aril cetona y composiciones para administrar principios activos
US20080132527A1 (en) 2004-05-19 2008-06-05 Emisphere Technologies, Inc. Compositions For Delivering Acyclovir
CN1968704B (zh) 2004-05-19 2010-12-08 爱密斯菲尔科技公司 局部用色甘酸制剂
WO2006072070A2 (en) 2004-12-29 2006-07-06 Emisphere Technologies, Inc. Pharmaceutical formulations of gallium salts
US8110547B2 (en) 2005-01-12 2012-02-07 Emisphere Technologies, Inc. Compositions for buccal delivery of parathyroid hormone
WO2007011958A2 (en) * 2005-07-15 2007-01-25 Emisphere Technologies, Inc. Intraoral dosage forms of glucagon
AU2006312117A1 (en) * 2005-11-04 2007-05-18 Genta Incorporated Pharmaceutical gallium compositions and methods
WO2007093363A1 (en) * 2006-02-15 2007-08-23 Sanofi-Aventis Novel azacycly-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
WO2007093365A2 (en) * 2006-02-15 2007-08-23 Sanofi-Aventis Novel amino alcohol-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
JP4857138B2 (ja) * 2006-03-23 2012-01-18 富士フイルム株式会社 レジスト組成物及びそれを用いたパターン形成方法
WO2007121318A2 (en) 2006-04-12 2007-10-25 Emisphere Technologies, Inc. Formulations for delivering insulin
EP2007372B1 (en) 2006-04-18 2015-03-04 Emisphere Technologies, Inc. Dialkyl ether delivery agents
WO2008003050A2 (en) 2006-06-28 2008-01-03 Emisphere Technologies, Inc. Gallium nitrate formulations
US20100062970A1 (en) 2006-08-18 2010-03-11 Emisphere Technologies Inc. Synthesis of propyl phenoxy ethers and use as delivery agents
CA2662853C (en) * 2006-08-31 2016-07-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
EP2129218B1 (en) * 2007-02-16 2016-10-19 Emisphere Technologies, Inc. Compounds having a cyclic moiety and compositions for delivering active agents
EP2461803B1 (en) 2009-08-03 2018-10-17 Emisphere Technologies, Inc. Fast-acting naproxen composition with reduced gastrointestinal effects
MX368045B (es) * 2012-08-23 2019-09-17 Emisphere Tech Inc Compuestos de diisopropanolamina y dietanolamina de fenoxialquilo para la administracion de agentes activos.
DK2897620T3 (da) 2012-09-21 2020-08-17 Intensity Therapeutics Inc Fremgangsmåde til behandling af cancer
CA2975710C (en) 2015-02-09 2023-08-08 Entera Bio Ltd. Treatment of osteoporosis
CN104961687B (zh) * 2015-06-03 2017-07-25 苏州维泰生物技术有限公司 1,2‑二嗪衍生物及其制剂、用途

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CH297705A (de) * 1950-09-16 1954-03-31 Cilag Ag Verfahren zur Herstellung eines neuen basischen Äthers.
GB710511A (en) * 1950-09-29 1954-06-16 Abbott Lab Improvements in or relating to aryl ethers of morpholino-alkanols and methods for the production thereof
GB1524260A (en) 1976-11-23 1978-09-06 Beecham Group Ltd Aminoalkyloneoxyd substituted 4-hydroxy-3 nitrocoumarins
JPS58113178A (ja) * 1981-12-28 1983-07-05 Yamanouchi Pharmaceut Co Ltd 「お」−（１−イミダゾリル）アルキルオキシ（またはチオ）ベンゼン誘導体
US4851423A (en) 1986-12-10 1989-07-25 Schering Corporation Pharmaceutically active compounds
CA1315279C (en) * 1987-01-12 1993-03-30 Nancy Grace Bollinger Anti-inflammatory agents
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WO1991000858A1 (en) 1989-07-07 1991-01-24 Schering Corporation Pharmaceutically active compounds
JPH0441472A (ja) 1990-06-05 1992-02-12 Sankyo Co Ltd グアニジノ安息香酸エステル誘導体
JPH04117461A (ja) 1990-09-07 1992-04-17 Asahi Denka Kogyo Kk 耐光性の改善された高分子材料組成物
JP2000256286A (ja) * 1999-03-11 2000-09-19 Kaken Pharmaceut Co Ltd アルキルアミン誘導体
KR100788970B1 (ko) * 1999-11-05 2007-12-27 에미스페어 테크놀로지스, 인코포레이티드 활성제 전달용 페녹시 카르복시산 화합물 및 조성물
WO2003045306A2 (en) 2001-11-13 2003-06-05 Emisphere Technologies, Inc. Phenoxy amine compounds and compositions for delivering active agents
WO2005115406A2 (en) * 2004-04-16 2005-12-08 Emisphere Technologies, Inc. 8-(2-hydroxyphenoxy)octyldiethanolamine and salts thereof for delivery of active agents
WO2006072070A2 (en) 2004-12-29 2006-07-06 Emisphere Technologies, Inc. Pharmaceutical formulations of gallium salts

Also Published As

Publication number Publication date
JP2005519875A (ja) 2005-07-07
EP1453816B1 (en) 2013-09-18
CN1596248B (zh) 2012-05-09
AU2002360387B2 (en) 2008-08-07
AU2002360387A1 (en) 2003-06-10
EP1453816A4 (en) 2005-02-09
EP1453816A2 (en) 2004-09-08
NZ532597A (en) 2006-04-28
US7297794B2 (en) 2007-11-20
ZA200403572B (en) 2005-09-28
US20050119502A1 (en) 2005-06-02
BR0214199A (pt) 2005-01-04
CN1596248A (zh) 2005-03-16
WO2003045306A2 (en) 2003-06-05
WO2003045306A3 (en) 2003-09-04
HK1069383A1 (en) 2005-05-20
CA2465641C (en) 2011-06-21
ES2431630T3 (es) 2013-11-27
JP4602668B2 (ja) 2010-12-22
CA2465641A1 (en) 2003-06-05

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