HK1069383A1 - Phenoxy amine compounds and compositions for delivering active agents - Google Patents

Phenoxy amine compounds and compositions for delivering active agents

Info

Publication number
HK1069383A1
HK1069383A1 HK05101082.2A HK05101082A HK1069383A1 HK 1069383 A1 HK1069383 A1 HK 1069383A1 HK 05101082 A HK05101082 A HK 05101082A HK 1069383 A1 HK1069383 A1 HK 1069383A1
Authority
HK
Hong Kong
Prior art keywords
compositions
active agents
amine compounds
delivering active
phenoxy amine
Prior art date
Application number
HK05101082.2A
Other languages
English (en)
Inventor
David Gschneidner
Kelly Kraft
Chen Zhu
Yi Chen
Original Assignee
Emisphere Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emisphere Tech Inc filed Critical Emisphere Tech Inc
Publication of HK1069383A1 publication Critical patent/HK1069383A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK05101082.2A 2001-11-13 2005-02-08 Phenoxy amine compounds and compositions for delivering active agents HK1069383A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35048801P 2001-11-13 2001-11-13
US35728802P 2002-02-15 2002-02-15
PCT/US2002/036552 WO2003045306A2 (en) 2001-11-13 2002-11-13 Phenoxy amine compounds and compositions for delivering active agents

Publications (1)

Publication Number Publication Date
HK1069383A1 true HK1069383A1 (en) 2005-05-20

Family

ID=26996636

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05101082.2A HK1069383A1 (en) 2001-11-13 2005-02-08 Phenoxy amine compounds and compositions for delivering active agents

Country Status (13)

Country Link
US (1) US7297794B2 (xx)
EP (1) EP1453816B1 (xx)
JP (1) JP4602668B2 (xx)
CN (1) CN1596248B (xx)
AU (1) AU2002360387B2 (xx)
BR (1) BR0214199A (xx)
CA (1) CA2465641C (xx)
ES (1) ES2431630T3 (xx)
HK (1) HK1069383A1 (xx)
MX (1) MXPA04004567A (xx)
NZ (1) NZ532597A (xx)
WO (1) WO2003045306A2 (xx)
ZA (1) ZA200403572B (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2431630T3 (es) 2001-11-13 2013-11-27 Emisphere Technologies, Inc. Compuestos de fenoxiamina y composiciones para administrar principios activos
NZ534125A (en) 2002-02-20 2006-11-30 Emisphere Tech Inc A formulation comprising a GLP-1 compound and a delivery agent
US20040076587A1 (en) * 2002-06-19 2004-04-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical composition for intranasal administration containing a CGRP antagonist
CN1688696A (zh) * 2002-09-18 2005-10-26 蒙特利尔大学医疗中心 Ghrh类似物
BRPI0509411A (pt) 2004-04-16 2007-09-04 Emisphere Tech Inc método para tratar doença maligna, hipercalcemia de malignidade e metástases ósseas osteolìticas, sal de mesilato, composição e método de administração de agente ativo e bisfosfonato
MXPA06013252A (es) 2004-05-14 2007-02-28 Emisphere Tech Inc Compuestos y composiciones para suministrar agentes activos.
WO2005117854A2 (en) 2004-05-14 2005-12-15 Emisphere Technologies, Inc. Aryl ketone compounds and compositions for delivering active agents
NZ551597A (en) 2004-05-19 2010-11-26 Emisphere Tech Inc Topical cromolyn formulations
US20080132527A1 (en) 2004-05-19 2008-06-05 Emisphere Technologies, Inc. Compositions For Delivering Acyclovir
AU2005321803B2 (en) 2004-12-29 2012-02-09 Emisphere Technologies, Inc. Pharmaceutical formulations of gallium salts
WO2006076692A1 (en) 2005-01-12 2006-07-20 Emisphere Technologies, Inc. Compositions for buccal delivery of parathyroid hormone
US8975227B2 (en) 2005-07-15 2015-03-10 Emisphere Technologies, Inc. Intraoral dosage forms of glucagon
EA200801261A1 (ru) * 2005-11-04 2008-08-29 Джента Инкорпорейтед Фармацевтические композиции на основе галлия и способы
BRPI0707869A2 (pt) * 2006-02-15 2011-05-10 Sanofi Aventis ariltienopirimidinonas substituÍdas com azaciclil, processo para a sua preparaÇço e seus usos como medicamentos
CN101384605A (zh) * 2006-02-15 2009-03-11 塞诺菲-安万特股份有限公司 新的氨基醇取代的芳基噻吩并嘧啶酮、其制备方法以及其作为药物的用途
JP4857138B2 (ja) * 2006-03-23 2012-01-18 富士フイルム株式会社 レジスト組成物及びそれを用いたパターン形成方法
WO2007121318A2 (en) 2006-04-12 2007-10-25 Emisphere Technologies, Inc. Formulations for delivering insulin
ES2538254T3 (es) 2006-04-18 2015-06-18 Emisphere Technologies, Inc. Agentes de administración de dialquil éter
EP2040718B1 (en) 2006-06-28 2017-12-27 Emisphere Technologies, Inc. Gallium nitrate formulations
WO2008022242A2 (en) 2006-08-18 2008-02-21 Emisphere Technologies, Inc. Synthesis of propyl phenoxy ethers and use as delivery agents
WO2008027958A2 (en) * 2006-08-31 2008-03-06 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
WO2008101240A1 (en) * 2007-02-16 2008-08-21 Emisphere Technologies, Inc. Compounds having a cyclic moiety and compositions for delivering active agents
EP2461803B1 (en) 2009-08-03 2018-10-17 Emisphere Technologies, Inc. Fast-acting naproxen composition with reduced gastrointestinal effects
BR112015003761B1 (pt) 2012-08-23 2022-02-15 Emisphere Technologies, Inc Composto, composição farmacêutica, forma unitária de dosageme método para preparar uma composição
SG11201501850VA (en) 2012-09-21 2015-04-29 Intensity Therapeutics Inc Method of treating cancer
WO2016128971A1 (en) 2015-02-09 2016-08-18 Entera Bio Ltd. Treatment of bone fractures and defects
CN104961687B (zh) * 2015-06-03 2017-07-25 苏州维泰生物技术有限公司 1,2‑二嗪衍生物及其制剂、用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH297705A (de) * 1950-09-16 1954-03-31 Cilag Ag Verfahren zur Herstellung eines neuen basischen Äthers.
GB710511A (en) * 1950-09-29 1954-06-16 Abbott Lab Improvements in or relating to aryl ethers of morpholino-alkanols and methods for the production thereof
GB1524260A (en) * 1976-11-23 1978-09-06 Beecham Group Ltd Aminoalkyloneoxyd substituted 4-hydroxy-3 nitrocoumarins
JPS58113178A (ja) * 1981-12-28 1983-07-05 Yamanouchi Pharmaceut Co Ltd 「お」−（１−イミダゾリル）アルキルオキシ（またはチオ）ベンゼン誘導体
US4851423A (en) * 1986-12-10 1989-07-25 Schering Corporation Pharmaceutically active compounds
CA1315279C (en) * 1987-01-12 1993-03-30 Nancy Grace Bollinger Anti-inflammatory agents
US5023253A (en) 1987-12-21 1991-06-11 University Patents, Inc. 6-substituted mitomycin analogs
EP0407217A1 (en) * 1989-07-07 1991-01-09 Schering Corporation Pharmaceutically active compounds
JPH0441472A (ja) * 1990-06-05 1992-02-12 Sankyo Co Ltd グアニジノ安息香酸エステル誘導体
JPH04117461A (ja) 1990-09-07 1992-04-17 Asahi Denka Kogyo Kk 耐光性の改善された高分子材料組成物
JP2000256286A (ja) * 1999-03-11 2000-09-19 Kaken Pharmaceut Co Ltd アルキルアミン誘導体
AU2622301A (en) 1999-11-05 2001-05-14 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
ES2431630T3 (es) 2001-11-13 2013-11-27 Emisphere Technologies, Inc. Compuestos de fenoxiamina y composiciones para administrar principios activos
BRPI0509411A (pt) 2004-04-16 2007-09-04 Emisphere Tech Inc método para tratar doença maligna, hipercalcemia de malignidade e metástases ósseas osteolìticas, sal de mesilato, composição e método de administração de agente ativo e bisfosfonato
AU2005321803B2 (en) 2004-12-29 2012-02-09 Emisphere Technologies, Inc. Pharmaceutical formulations of gallium salts

Also Published As

Publication number Publication date
CN1596248A (zh) 2005-03-16
AU2002360387B2 (en) 2008-08-07
EP1453816A4 (en) 2005-02-09
AU2002360387A1 (en) 2003-06-10
JP2005519875A (ja) 2005-07-07
CN1596248B (zh) 2012-05-09
NZ532597A (en) 2006-04-28
US7297794B2 (en) 2007-11-20
ES2431630T3 (es) 2013-11-27
JP4602668B2 (ja) 2010-12-22
US20050119502A1 (en) 2005-06-02
EP1453816A2 (en) 2004-09-08
ZA200403572B (en) 2005-09-28
WO2003045306A3 (en) 2003-09-04
BR0214199A (pt) 2005-01-04
CA2465641A1 (en) 2003-06-05
WO2003045306A2 (en) 2003-06-05
MXPA04004567A (es) 2004-09-10
CA2465641C (en) 2011-06-21
EP1453816B1 (en) 2013-09-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20171113