MX9707005A - Composiciones farmaceuticas que contienen 2,6-diisopropilfenol (propofol). - Google Patents
Composiciones farmaceuticas que contienen 2,6-diisopropilfenol (propofol).Info
- Publication number
- MX9707005A MX9707005A MX9707005A MX9707005A MX9707005A MX 9707005 A MX9707005 A MX 9707005A MX 9707005 A MX9707005 A MX 9707005A MX 9707005 A MX9707005 A MX 9707005A MX 9707005 A MX9707005 A MX 9707005A
- Authority
- MX
- Mexico
- Prior art keywords
- edetate
- oil
- water emulsions
- emulsions containing
- containing propofol
- Prior art date
Links
- OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical compound CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004134 propofol Drugs 0.000 title abstract 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 title 1
- 229940009662 edetate Drugs 0.000 title 1
- 239000000839 emulsion Substances 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
- 206010002091 Anaesthesia Diseases 0.000 abstract 2
- 238000001949 anaesthesia Methods 0.000 abstract 2
- 230000037005 anaesthesia Effects 0.000 abstract 2
- 206010039897 Sedation Diseases 0.000 abstract 1
- 229940124326 anaesthetic agent Drugs 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 238000012423 maintenance Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000036280 sedation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Colloid Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
Abstract
Se describen composiciones farmacéuticas que contienen 2,6-diisopropilfenol (propofol) para su uso como anestésicos. Se describe un método para su preparacion, así como su uso en la produccion de anestesia incluyendo su induccion y mantenimiento de una anestesia general y sedantes.
Applications Claiming Priority (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9405593A GB9405593D0 (en) | 1994-03-22 | 1994-03-22 | Pharmaceutical compositions |
FR9503128A FR2731617B1 (fr) | 1994-03-22 | 1995-03-17 | Compositions pharmaceutiques nouvelles contenant du propofol |
BR9510452A BR9510452A (pt) | 1994-03-22 | 1995-03-17 | Composição farmacêutica e aquosa estéril para a administração parenteral processos para limitar o potencial de crescimento microbiano em composição farmacêutica estéril para a administração parenteral para produzir anestesia em um animal de sangue quente e para aperfeiçoar o tempo de administração e/ou o tempo entre as trocas de conjuntos |
NZ500588A NZ500588A (en) | 1994-03-22 | 1995-03-17 | Oil in water emulsions containing propofol and edetate for producing anaesthesia |
CH00393/03A CH693762A5 (de) | 1994-03-22 | 1995-03-17 | Wässrige Zusammensetzungen enthaltend eine Öl-in-Wasser-Emulsion |
DE19509828A DE19509828A1 (de) | 1994-03-22 | 1995-03-17 | Pharmazeutische Zusammensetzungen |
PL95322278A PL186354B1 (pl) | 1994-03-22 | 1995-03-17 | Jałowe kompozycje farmaceutyczne oraz sposoby ograniczania potencjału wzrostowego drobnoustrojów i poprawiania czasu stosowania emulsji |
BE9500241A BE1009198A5 (fr) | 1994-03-22 | 1995-03-17 | Compositions pharmaceutiques nouvelles contenant du propofol. |
NZ282005A NZ282005A (en) | 1994-03-22 | 1995-03-17 | Oil in water emulsions containing propofol (2,6 diisopropylphenol) and edetate |
PCT/GB1995/000579 WO1996029064A1 (en) | 1994-03-22 | 1995-03-17 | Oil in water emulsions containing propofol and edetate |
CA002212794A CA2212794C (en) | 1994-03-22 | 1995-03-17 | Oil in water emulsions containing propofol and edetate |
CH02011/97A CH693764A5 (de) | 1994-03-22 | 1995-03-17 | Pharmazeutische Zusammensetzung enthaltend Propofol und Edetat. |
HU9702180A HU227951B1 (en) | 1994-03-22 | 1995-03-17 | Oil in water emulsions containing propofol and disodium edetate |
ZA952239A ZA952239B (en) | 1994-03-22 | 1995-03-17 | Pharmaceutical compositions |
CH01282/04A CH694423A5 (de) | 1994-03-22 | 1995-03-17 | Verwendung von Edetat zur Stabilisierung von pharmzeutischen Zusammensetzungen. |
EP95911412A EP0814787B1 (en) | 1994-03-22 | 1995-03-17 | Oil in water emulsions containing propofol and disodium edetate |
NO19974278A NO320007B1 (no) | 1994-03-22 | 1997-09-16 | Steril farmasoytisk blanding inneholdende propofol og edetat for parenteral administrering, fremgangsmate for a begrense potensialet for mikrobevekst i blandingen, samt anvendelse derav. |
JP00624199A JP4012328B2 (ja) | 1994-03-22 | 1999-01-13 | エデテートを含有する水中油滴エマルジョン |
FI20085586A FI120641B (fi) | 1994-03-22 | 2008-06-13 | Ruuansulatuskanavan ulkopuolisesti annettavat rasvaemulsiot, jotka sisältävät edetaattia säilöntäaineena |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9707005A true MX9707005A (es) | 1997-11-29 |
Family
ID=48793621
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9707005A MX9707005A (es) | 1994-03-22 | 1995-03-17 | Composiciones farmaceuticas que contienen 2,6-diisopropilfenol (propofol). |
Country Status (33)
Country | Link |
---|---|
US (1) | US5714520A (es) |
EP (2) | EP1238677B1 (es) |
JP (2) | JP3067806B2 (es) |
AT (2) | ATE226817T1 (es) |
AU (1) | AU710143B2 (es) |
BE (1) | BE1009198A5 (es) |
BR (1) | BR9510452A (es) |
CA (1) | CA2212794C (es) |
CH (4) | CH693762A5 (es) |
CZ (1) | CZ297549B6 (es) |
DE (2) | DE19509828A1 (es) |
DK (3) | DK0814787T3 (es) |
ES (2) | ES2183869T3 (es) |
FI (2) | FI120640B (es) |
FR (1) | FR2731617B1 (es) |
GB (2) | GB9405593D0 (es) |
HK (1) | HK1008927A1 (es) |
HU (1) | HU227951B1 (es) |
IL (1) | IL113021A (es) |
IT (1) | IT1281193B1 (es) |
LU (1) | LU90136B1 (es) |
MX (1) | MX9707005A (es) |
NO (2) | NO320007B1 (es) |
NZ (2) | NZ500588A (es) |
PL (1) | PL186354B1 (es) |
PT (1) | PT814787E (es) |
RU (1) | RU2147432C1 (es) |
SE (2) | SE523909C2 (es) |
SI (1) | SI0814787T1 (es) |
SK (1) | SK286375B6 (es) |
TW (1) | TW458781B (es) |
WO (1) | WO1996029064A1 (es) |
ZA (1) | ZA952239B (es) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6749868B1 (en) | 1993-02-22 | 2004-06-15 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
US5916596A (en) * | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
US20020173547A1 (en) | 1994-03-22 | 2002-11-21 | Jones Christopher Buchan | Pharmaceuticals compositions |
GB9405593D0 (en) * | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
MY113046A (en) * | 1994-03-22 | 2001-11-30 | Astrazeneca Uk Ltd | Pharmaceutical compositions |
US5637625A (en) * | 1996-03-19 | 1997-06-10 | Research Triangle Pharmaceuticals Ltd. | Propofol microdroplet formulations |
KR19980025601A (ko) * | 1996-10-04 | 1998-07-15 | 우동일 | 혈관주사제용 프로포폴 유탁액의 제조방법 |
CH692322A5 (it) * | 1997-05-26 | 2002-05-15 | Westy Ag | Formulazione iniettabile limpida di Propofol. |
US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
DE19757224A1 (de) | 1997-12-22 | 1999-07-01 | Bayer Ag | Verfahren und Vorrichtung zur in-situ-Formulierung einer Arzneistofflösung zur parenteralen Applikation |
US6147122A (en) * | 1998-02-10 | 2000-11-14 | Gensia Sincor Inc. | Propofol composition containing sulfite |
US6254853B1 (en) | 1998-05-08 | 2001-07-03 | Vyrex Corporation | Water soluble pro-drugs of propofol |
JP4198318B2 (ja) * | 1998-08-19 | 2008-12-17 | ヤーゴテック アクチェンゲゼルシャフト | プロポフォールの注射可能水性分散物 |
US6150423A (en) | 1998-10-15 | 2000-11-21 | Phoenix Scientific, Inc. | Propofol-based anesthetic and method of making same |
US6028108A (en) * | 1998-10-22 | 2000-02-22 | America Home Products Corporation | Propofol composition comprising pentetate |
US6140374A (en) * | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
US6140373A (en) * | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
US6682758B1 (en) | 1998-12-22 | 2004-01-27 | The United States Of America As Represented By The Department Of Health And Human Services | Water-insoluble drug delivery system |
DE69922252T2 (de) * | 1999-01-28 | 2005-12-01 | Patel, Dinesh Shantilal | Parenterale lösungen enthaltend propofol (2,6-diisopropylphenol) und 2.5-di-0-methyl-1.4;3.6-dianhydro-d-glucitol als lösungsmittel |
US6177477B1 (en) * | 1999-03-24 | 2001-01-23 | American Home Products Corporation | Propofol formulation containing TRIS |
US6100302A (en) * | 1999-04-05 | 2000-08-08 | Baxter International Inc. | Propofol formulation with enhanced microbial characteristics |
ES2261210T3 (es) * | 1999-06-21 | 2006-11-16 | Kuhnil Pharmaceutical Co., Ltd. | Comoposicion anestesica para inyeccion intravenosa que comprende propofol. |
GB2359747B (en) | 2000-02-29 | 2002-04-24 | Maelor Pharmaceuticals Ltd | Anaesthetic formulations |
SE0001865D0 (sv) * | 2000-05-19 | 2000-05-19 | Astrazeneca Ab | Management of septic shock |
IL152774A0 (en) * | 2000-05-25 | 2003-06-24 | Astrazeneca Ab | Pharmaceutical composition comprising a free-radical scavenging sedative agent and a metal ion chelating agent |
GB0012597D0 (en) * | 2000-05-25 | 2000-07-12 | Astrazeneca Ab | Formulation |
AU6689601A (en) | 2000-06-16 | 2002-01-02 | Rtp Pharma Inc | Improved injectable dispersions of propofol |
IN188917B (es) * | 2000-12-07 | 2002-11-23 | Bharat Surums & Vaccines Ltd | |
KR100921199B1 (ko) | 2001-05-11 | 2009-10-13 | 미쓰비시 타나베 파마 코퍼레이션 | 안정하고 고농도인 피라졸론 유도체를 포함하는 주사제 |
JP4127757B2 (ja) * | 2001-08-21 | 2008-07-30 | 株式会社エヌ・ティ・ティ・ドコモ | 無線通信システム、通信端末装置、及びバースト信号送信方法 |
US20030054042A1 (en) * | 2001-09-14 | 2003-03-20 | Elaine Liversidge | Stabilization of chemical compounds using nanoparticulate formulations |
US8541472B2 (en) | 2001-12-05 | 2013-09-24 | Aseptica, Inc. | Antiseptic compositions, methods and systems |
RU2315037C2 (ru) | 2002-01-25 | 2008-01-20 | Тереванс, Инк. | Замещенные эфиры фенилуксусной кислоты в качестве короткодействующих седативных снотворных агентов для кратковременной анестезии и создания седативного эффекта, промежуточное соединение, фармацевтическая композиция и применение |
US20080220075A1 (en) * | 2002-03-20 | 2008-09-11 | Elan Pharma International Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
ATE343376T1 (de) * | 2002-03-20 | 2006-11-15 | Elan Pharma Int Ltd | Nanopartikelzusammensetzungen von angiogeneseinhibitoren |
AU2003224851B2 (en) * | 2002-04-08 | 2008-04-03 | Eisai Inc. | Pharmaceutical compositions containing water-soluble prodrugs of propofol and methods of administering same |
US7550155B2 (en) | 2002-07-29 | 2009-06-23 | Transform Pharmaceuticals Inc. | Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses |
WO2004010941A2 (en) | 2002-07-29 | 2004-02-05 | Transform Pharmaceuticals, Inc. | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
JP2006504771A (ja) * | 2002-10-29 | 2006-02-09 | トランスフォーム・ファーマシューティカルズ・インコーポレイテッド | システインを伴うプロポフォール |
TR200502189T1 (tr) | 2002-12-09 | 2007-01-22 | American Bioscience, Inc. | Kompozisyonlar ve farmakolojik etken maddelerin aktarımı için yöntemler. |
US20040225022A1 (en) * | 2003-05-09 | 2004-11-11 | Desai Neil P. | Propofol formulation containing reduced oil and surfactants |
US8476010B2 (en) | 2003-07-10 | 2013-07-02 | App Pharmaceuticals Llc | Propofol formulations with non-reactive container closures |
EP1648413B1 (en) * | 2003-07-23 | 2009-10-07 | Theravance, Inc. | Pharmaceutical compositions of short-acting sedative hypnotic agent |
US8546453B2 (en) * | 2003-08-14 | 2013-10-01 | Rensheng Zhang | Propofol compositions and methods for reducing pain associated with propofol injection |
EP1680409A4 (en) * | 2003-10-24 | 2007-12-05 | Auspex Pharmaceuticals Inc | PH-SENSITIVE 2,6-DIISOPROPYLPHENOL PROMEDICAMENTS |
BRPI0506812B8 (pt) | 2004-02-13 | 2021-05-25 | Bioavailability Inc | composição base anidra auto-microemulsificável, microemulsão e método de preparação da composição base automicroemulsificável |
WO2006030450A2 (en) * | 2004-09-13 | 2006-03-23 | Bharat Serums & Vaccines Ltd. | Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy |
US8557861B2 (en) * | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
EP1850829A4 (en) * | 2005-02-03 | 2012-12-26 | Taro Pharmaceuticals Usa Inc | NEW PROPOLFOL COMPOSITION WITH ASCORBIC ACID OR PHARMACEUTICALLY USEFUL SALTS |
CA2598159A1 (en) | 2005-02-18 | 2006-08-24 | Abraxis Bioscience, Inc. | Compositions, methods of use and preparation of 2,6-diisopropyl phenol and analogs for ischemic injury |
US20090131538A1 (en) * | 2005-05-27 | 2009-05-21 | Taro Pharmaceuticals North America, Inc. c/o Taro Pharmaceuticals U.S.A., Inc. | Novel propofol composition comprising a pharmaceutically acceptable salt of formaldehyde sulfoxylate |
EA200800258A1 (ru) * | 2005-08-05 | 2008-06-30 | Бхарат Сирумс Энд Вэксинс Лтд. | Эмульсионные композиции пропофола для внутривенного введения, имеющие консервирующую эффективность |
JP2009504634A (ja) * | 2005-08-12 | 2009-02-05 | ブハラット セルムズ アンド ヴァクシンズ リミテッド | プロポフォールを含む水性麻酔剤組成物 |
WO2007022437A2 (en) * | 2005-08-18 | 2007-02-22 | Auspex Pharmaceuticals, Inc. | Therapeutic agents for the treatment of cancer and metabolic disorders |
HUE048521T2 (hu) | 2005-08-31 | 2020-08-28 | Abraxis Bioscience Llc | Gyengén vízoldékony gyógyszerészeti és antimikrobális hatóanyagokat tartalmazó keverékek |
KR101457834B1 (ko) * | 2005-08-31 | 2014-11-05 | 아브락시스 바이오사이언스, 엘엘씨 | 증가된 안정성을 가진 수 난용성 약물의 조성물 및 제조 방법 |
US7589239B2 (en) * | 2005-09-02 | 2009-09-15 | Auspex Pharmaceuticals | Therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders |
TWI376239B (en) * | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
CN1903187B (zh) * | 2006-03-21 | 2012-05-30 | 沈阳药科大学 | 含有局麻药的复方异丙酚注射剂及制备工艺 |
EP2392559A1 (en) * | 2007-05-09 | 2011-12-07 | Pharmacofore, Inc. | Therapeutic compounds |
PL2146946T3 (pl) * | 2007-05-09 | 2011-04-29 | Pharmacofore Inc | (-)-Stereoizomer 2,6-di-sec-butylofenolu i jego analogi |
KR20080102010A (ko) * | 2007-05-17 | 2008-11-24 | 대원제약주식회사 | 프로포폴을 포함하는 주사제용 조성물 및 이의 제조 방법 |
PL2320740T3 (pl) | 2008-08-01 | 2014-09-30 | The Medicines Co | Kompozycje farmaceutyczne klewidypiny oraz sposoby ich wytwarzania z niskim stężeniem zanieczyszczeń |
US9132090B2 (en) | 2009-01-13 | 2015-09-15 | Chetan Majmudar | Propofol based anesthetic with preservative |
MX2013004151A (es) | 2010-10-12 | 2013-05-20 | Medicines Co | Formulaciones de emulsion de clevidipina que contienen agentes antimicrobianos. |
US8658676B2 (en) | 2010-10-12 | 2014-02-25 | The Medicines Company | Clevidipine emulsion formulations containing antimicrobial agents |
CN102407986B (zh) * | 2011-11-03 | 2013-11-27 | 南通四方冷链装备股份有限公司 | 隔料装置 |
CN102525921B (zh) * | 2012-02-06 | 2013-08-07 | 西安力邦制药有限公司 | 2,2’,6,6’-四异丙基-4,4’-二联苯酚脂微球制剂及其制备方法 |
CN102579555A (zh) * | 2012-03-01 | 2012-07-18 | 四川大学华西医院 | 注射用脂肪乳在作为拮抗全身麻醉用药作用的药物制备中的应用 |
MX2014013826A (es) | 2012-05-16 | 2018-04-24 | Singh Mewa | Composiciones farmaceuticas para la entrega de farmacos sustancialmente solubles en agua. |
US11622937B2 (en) | 2015-08-20 | 2023-04-11 | Mewa Singh | Polyphenolic polymer to make water-insoluble molecules become water-soluble |
WO2018195292A1 (en) | 2017-04-19 | 2018-10-25 | Mayo Foundation For Medical Education And Research | Ketamine and propofol admixture |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3384545A (en) * | 1965-03-09 | 1968-05-21 | Hoffmann La Roche | Injectable aqueous emulsions of fat soluble vitamins |
US3230143A (en) * | 1965-05-14 | 1966-01-18 | Merck & Co Inc | Antihypertensive injection methods using acid addition salts of alkyl esters of alpha-methyl-3, 4-dihy-droxyphenylalanine |
DE1792410B2 (de) * | 1967-09-01 | 1980-03-13 | Apoteksvarucentralen Vitrum Apotekareaktiebolaget, Stockholm | Arzneimittelzubereitung zur intravenösen Injektion |
US4798846A (en) * | 1974-03-28 | 1989-01-17 | Imperial Chemical Industries Plc | Pharmaceutical compositions |
GB1472793A (en) * | 1974-03-28 | 1977-05-04 | Ici Ltd | Pharmaceutical compositions |
US4328213A (en) * | 1979-11-28 | 1982-05-04 | Schering Corporation | Stable injectable labetalol formulation |
DE3225706C2 (de) * | 1982-07-09 | 1984-04-26 | A. Nattermann & Cie GmbH, 5000 Köln | Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen |
JPS5916818A (ja) * | 1982-07-20 | 1984-01-28 | Shimizu Seiyaku Kk | 経静脈投与用輸液剤 |
SE8505047L (sv) * | 1985-10-25 | 1987-04-26 | Nutritional Int Res Inst | Fettemulsion |
IL83086A (en) * | 1987-07-06 | 1991-03-10 | Teva Pharma | Stable,injectable solutions of vincristine salts |
US4868169A (en) * | 1987-11-13 | 1989-09-19 | E. R. Squibb & Sons, Inc. | Steroid cream formulation |
JPH075456B2 (ja) * | 1988-10-01 | 1995-01-25 | 参天製薬株式会社 | 点眼液 |
AU636591B2 (en) * | 1988-11-29 | 1993-05-06 | Abbott Laboratories | Blood diluent for red blood cell analysis |
GB8828517D0 (en) * | 1988-12-07 | 1989-01-11 | Leopold & Co Ag | Stable emulsions |
US5079003A (en) * | 1990-03-14 | 1992-01-07 | Adelia Scaffidi | Skin lotions and creams |
JP3308555B2 (ja) * | 1991-03-08 | 2002-07-29 | カネボウ株式会社 | 微細化エマルション組成物の製造方法 |
JP2811036B2 (ja) * | 1992-05-26 | 1998-10-15 | 参天製薬株式会社 | ビタミンe点眼剤 |
GB9405593D0 (en) * | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
-
1994
- 1994-03-22 GB GB9405593A patent/GB9405593D0/en active Pending
-
1995
- 1995-03-17 DK DK95911412T patent/DK0814787T3/da active
- 1995-03-17 TW TW084102594A patent/TW458781B/zh not_active IP Right Cessation
- 1995-03-17 CZ CZ0290497A patent/CZ297549B6/cs not_active IP Right Cessation
- 1995-03-17 IL IL11302195A patent/IL113021A/en not_active IP Right Cessation
- 1995-03-17 ES ES95911412T patent/ES2183869T3/es not_active Expired - Lifetime
- 1995-03-17 CH CH00393/03A patent/CH693762A5/de not_active IP Right Cessation
- 1995-03-17 CH CH02053/03A patent/CH694396A5/de not_active IP Right Cessation
- 1995-03-17 DE DE19509828A patent/DE19509828A1/de not_active Ceased
- 1995-03-17 NZ NZ500588A patent/NZ500588A/en not_active IP Right Cessation
- 1995-03-17 MX MX9707005A patent/MX9707005A/es unknown
- 1995-03-17 PT PT95911412T patent/PT814787E/pt unknown
- 1995-03-17 AU AU18988/95A patent/AU710143B2/en not_active Expired
- 1995-03-17 DE DE69528714T patent/DE69528714T2/de not_active Expired - Lifetime
- 1995-03-17 IT IT95MI000529A patent/IT1281193B1/it active IP Right Grant
- 1995-03-17 CH CH01282/04A patent/CH694423A5/de not_active IP Right Cessation
- 1995-03-17 ES ES02009330T patent/ES2253469T3/es not_active Expired - Lifetime
- 1995-03-17 EP EP02009330A patent/EP1238677B1/en not_active Expired - Lifetime
- 1995-03-17 FR FR9503128A patent/FR2731617B1/fr not_active Expired - Lifetime
- 1995-03-17 SI SI9530628T patent/SI0814787T1/xx unknown
- 1995-03-17 CH CH02011/97A patent/CH693764A5/de not_active IP Right Cessation
- 1995-03-17 HU HU9702180A patent/HU227951B1/hu unknown
- 1995-03-17 JP JP08528148A patent/JP3067806B2/ja not_active Expired - Lifetime
- 1995-03-17 AT AT95911412T patent/ATE226817T1/de active
- 1995-03-17 CA CA002212794A patent/CA2212794C/en not_active Expired - Fee Related
- 1995-03-17 BR BR9510452A patent/BR9510452A/pt not_active IP Right Cessation
- 1995-03-17 BE BE9500241A patent/BE1009198A5/fr active
- 1995-03-17 ZA ZA952239A patent/ZA952239B/xx unknown
- 1995-03-17 DK DK02009330T patent/DK1238677T3/da active
- 1995-03-17 EP EP95911412A patent/EP0814787B1/en not_active Expired - Lifetime
- 1995-03-17 GB GB9505405A patent/GB2298789B/en not_active Expired - Lifetime
- 1995-03-17 SK SK1247-97A patent/SK286375B6/sk not_active IP Right Cessation
- 1995-03-17 NZ NZ282005A patent/NZ282005A/xx not_active IP Right Cessation
- 1995-03-17 AT AT02009330T patent/ATE312625T1/de active
- 1995-03-17 RU RU97117100A patent/RU2147432C1/ru active
- 1995-03-17 WO PCT/GB1995/000579 patent/WO1996029064A1/en active Application Filing
- 1995-03-17 PL PL95322278A patent/PL186354B1/pl unknown
- 1995-03-22 US US08/408,707 patent/US5714520A/en not_active Expired - Lifetime
-
1997
- 1997-09-10 LU LU90136A patent/LU90136B1/de active
- 1997-09-10 SE SE9703274A patent/SE523909C2/sv not_active IP Right Cessation
- 1997-09-16 FI FI973702A patent/FI120640B/fi not_active IP Right Cessation
- 1997-09-16 NO NO19974278A patent/NO320007B1/no not_active IP Right Cessation
- 1997-09-17 DK DK106697A patent/DK106697A/da not_active Application Discontinuation
-
1998
- 1998-08-04 HK HK98109677A patent/HK1008927A1/xx not_active IP Right Cessation
-
1999
- 1999-01-13 JP JP00624199A patent/JP4012328B2/ja not_active Expired - Lifetime
-
2004
- 2004-01-21 SE SE0400115A patent/SE527123C2/sv not_active IP Right Cessation
- 2004-05-04 NO NO20041838A patent/NO334956B1/no not_active IP Right Cessation
-
2008
- 2008-06-13 FI FI20085586A patent/FI120641B/fi not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9707005A (es) | Composiciones farmaceuticas que contienen 2,6-diisopropilfenol (propofol). | |
BRPI9909282A (pt) | compostos de éter aminociclohexílicos e usos dos mesmos. | |
DE69737510D1 (de) | Verwendung eines unverkapselten anti-krebs-wirkstoffs zur herstellung einer zubereitung zur behandlung von neoplasmen durch inhalation | |
DE69310518D1 (de) | Pharmazeutische zusammensetzung zur topischen anwendung die ein vernetztes kationisches polymer und einen alkoxylierte äther enthält | |
SI0785948T1 (en) | Analogs of keratinocyte growth factor | |
BR9709535A (pt) | Composição para formação de um revestimento entérico em uma preparação oral,preparação oral provida com um revestmento entérico,e , processo para a preparação de um revestimento entérico em uma preparação oral contendo bactérias vivas | |
GR3036681T3 (en) | Pharmaceutical compositions derived from microelmulsion-based gels, method for their preparation and new microemulsion-based gels | |
PL318172A1 (en) | Novel analgesic pharmaceutic preparation | |
DE69530308D1 (de) | Verfahren zur herstellung von dosierungsformen durch feuchtgranulierung | |
IL114598A0 (en) | Triazole compounds their preparation and pharmaceutical compositions containing them | |
AU2096897A (en) | Serum cholesterol lowering agent | |
CA1261322A (en) | OXADIAZOLYLIMIDABENZODIAZEPINE DERIVATIVES; METHOD OF PREPARATION; PHARMACEUTICAL COMPOSITIONS AND TREATMENT BASED ON THESE DERIVATIVES | |
IL146190A0 (en) | Dermal anesthetic agents | |
HU9402761D0 (en) | Bis-aryl-carbinol derivatives, pharmaceutical compositions containing them and process for producing | |
ATE85334T1 (de) | Bisphenylalkylpiperazin-derivate, verfahren zur herstellung und arzneimittelzubereitung. | |
IS4251A (is) | Ný píperídín-4-karboxamíð sem hafa kvalastillandiog staðdeyfandi áhrif | |
ES2138130T3 (es) | Composicion farmaceutica que contiene un anestesico local y/o un analgesico de accion central. | |
DE69507150D1 (de) | Gelbildende präparate, die optisch angereicherte gelbildner enthalten | |
MY113046A (en) | Pharmaceutical compositions | |
FR2724933B1 (es) | ||
DE59607683D1 (de) | Neue borneolderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung | |
HUT75019A (en) | Method for producing pesticide compositions | |
DE69434002D1 (de) | 2,3 diaryl-1-benzopyrame zur behandlung von dermatitis | |
DE69514512D1 (de) | Verfahren zur herstellung von benzopyranderivaten | |
DE69618340D1 (de) | Verfahren zur herstellung von substituierten anthrachinonen und deren verwendung zur herstellung von rheinen |