MX2016007965A - Terapia de combinacion que comprende agonistas de union a ox40 y antagonistas de union al eje pd-1. - Google Patents
Terapia de combinacion que comprende agonistas de union a ox40 y antagonistas de union al eje pd-1.Info
- Publication number
- MX2016007965A MX2016007965A MX2016007965A MX2016007965A MX2016007965A MX 2016007965 A MX2016007965 A MX 2016007965A MX 2016007965 A MX2016007965 A MX 2016007965A MX 2016007965 A MX2016007965 A MX 2016007965A MX 2016007965 A MX2016007965 A MX 2016007965A
- Authority
- MX
- Mexico
- Prior art keywords
- binding
- combination therapy
- agonists
- antagonists
- axis
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title abstract 2
- 238000002648 combination therapy Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102100022153 Tumor necrosis factor receptor superfamily member 4 Human genes 0.000 abstract 1
- 101710165473 Tumor necrosis factor receptor superfamily member 4 Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361917264P | 2013-12-17 | 2013-12-17 | |
| US201462080991P | 2014-11-17 | 2014-11-17 | |
| PCT/US2014/070998 WO2015095423A2 (en) | 2013-12-17 | 2014-12-17 | Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016007965A true MX2016007965A (es) | 2016-10-28 |
Family
ID=52293264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016007965A MX2016007965A (es) | 2013-12-17 | 2014-12-17 | Terapia de combinacion que comprende agonistas de union a ox40 y antagonistas de union al eje pd-1. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20150190506A1 (enExample) |
| EP (2) | EP3527587A1 (enExample) |
| JP (1) | JP2017501167A (enExample) |
| KR (1) | KR20160099092A (enExample) |
| CN (1) | CN106102774A (enExample) |
| AU (1) | AU2014364606A1 (enExample) |
| BR (1) | BR112016013963A2 (enExample) |
| CA (1) | CA2934028A1 (enExample) |
| IL (1) | IL246251A0 (enExample) |
| MX (1) | MX2016007965A (enExample) |
| SG (1) | SG11201604979WA (enExample) |
| WO (1) | WO2015095423A2 (enExample) |
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| US10968276B2 (en) | 2013-03-12 | 2021-04-06 | Xencor, Inc. | Optimized anti-CD3 variable regions |
| US9605084B2 (en) | 2013-03-15 | 2017-03-28 | Xencor, Inc. | Heterodimeric proteins |
| DK2943511T3 (da) | 2013-01-14 | 2019-10-21 | Xencor Inc | Nye heterodimeriske proteiner |
| US11053316B2 (en) | 2013-01-14 | 2021-07-06 | Xencor, Inc. | Optimized antibody variable regions |
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-
2014
- 2014-12-17 US US14/574,365 patent/US20150190506A1/en not_active Abandoned
- 2014-12-17 JP JP2016540597A patent/JP2017501167A/ja active Pending
- 2014-12-17 SG SG11201604979WA patent/SG11201604979WA/en unknown
- 2014-12-17 WO PCT/US2014/070998 patent/WO2015095423A2/en not_active Ceased
- 2014-12-17 EP EP18206645.6A patent/EP3527587A1/en not_active Withdrawn
- 2014-12-17 MX MX2016007965A patent/MX2016007965A/es unknown
- 2014-12-17 CA CA2934028A patent/CA2934028A1/en not_active Abandoned
- 2014-12-17 CN CN201480073061.9A patent/CN106102774A/zh active Pending
- 2014-12-17 KR KR1020167018833A patent/KR20160099092A/ko not_active Withdrawn
- 2014-12-17 BR BR112016013963A patent/BR112016013963A2/pt not_active Application Discontinuation
- 2014-12-17 EP EP14824702.6A patent/EP3083687A2/en not_active Withdrawn
- 2014-12-17 AU AU2014364606A patent/AU2014364606A1/en not_active Abandoned
-
2016
- 2016-06-15 IL IL246251A patent/IL246251A0/en unknown
-
2018
- 2018-02-01 US US15/886,454 patent/US20180303936A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20160099092A (ko) | 2016-08-19 |
| IL246251A0 (en) | 2016-07-31 |
| US20180303936A1 (en) | 2018-10-25 |
| EP3527587A1 (en) | 2019-08-21 |
| US20150190506A1 (en) | 2015-07-09 |
| CA2934028A1 (en) | 2015-06-25 |
| WO2015095423A3 (en) | 2015-08-13 |
| EP3083687A2 (en) | 2016-10-26 |
| CN106102774A (zh) | 2016-11-09 |
| AU2014364606A1 (en) | 2016-07-07 |
| JP2017501167A (ja) | 2017-01-12 |
| BR112016013963A2 (pt) | 2017-10-10 |
| WO2015095423A2 (en) | 2015-06-25 |
| SG11201604979WA (en) | 2016-07-28 |
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