LU90875I2 - Aza-cyclohexapeptides - Google Patents

Aza-cyclohexapeptides

Info

Publication number
LU90875I2
LU90875I2 LU90875C LU90875C LU90875I2 LU 90875 I2 LU90875 I2 LU 90875I2 LU 90875 C LU90875 C LU 90875C LU 90875 C LU90875 C LU 90875C LU 90875 I2 LU90875 I2 LU 90875I2
Authority
LU
Luxembourg
Prior art keywords
aza
cyclohexapeptides
ceretain
found
preparation
Prior art date
Application number
LU90875C
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21867140&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90875(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of LU90875I2 publication Critical patent/LU90875I2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU90875C 1993-03-16 2002-01-03 Aza-cyclohexapeptides LU90875I2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/032,847 US5378804A (en) 1993-03-16 1993-03-16 Aza cyclohexapeptide compounds

Publications (1)

Publication Number Publication Date
LU90875I2 true LU90875I2 (en) 2002-03-04

Family

ID=21867140

Family Applications (1)

Application Number Title Priority Date Filing Date
LU90875C LU90875I2 (en) 1993-03-16 2002-01-03 Aza-cyclohexapeptides

Country Status (32)

Country Link
US (3) US5378804A (ro)
EP (1) EP0620232B1 (ro)
JP (1) JP2568474B2 (ro)
KR (1) KR100329693B1 (ro)
CN (1) CN1098274C (ro)
AT (1) ATE186736T1 (ro)
AU (1) AU668804B2 (ro)
BG (1) BG63047B1 (ro)
BR (2) BR9406009A (ro)
CA (1) CA2118757C (ro)
CZ (1) CZ286235B6 (ro)
DE (2) DE10299013I2 (ro)
DK (1) DK0620232T3 (ro)
ES (1) ES2139043T3 (ro)
FI (1) FI109542B (ro)
GR (1) GR3031872T3 (ro)
HR (1) HRP940161B1 (ro)
HU (2) HU217614B (ro)
IL (1) IL108892A (ro)
LU (1) LU90875I2 (ro)
LV (1) LV12574B (ro)
NL (1) NL300076I2 (ro)
NO (2) NO318372B1 (ro)
NZ (1) NZ263360A (ro)
PL (1) PL179261B1 (ro)
RO (1) RO113246B1 (ro)
RU (1) RU2122548C1 (ro)
SI (1) SI9420013B (ro)
SK (1) SK282527B6 (ro)
UA (1) UA59329C2 (ro)
WO (1) WO1994021677A1 (ro)
ZA (1) ZA941807B (ro)

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US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
CA2195975C (en) * 1994-08-23 2001-05-15 James M. Balkovec An improved process for preparing side chain derivatives of cyclohexapeptidyl lipopeptides
US5514651A (en) * 1994-09-16 1996-05-07 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
ES2181790T3 (es) * 1994-09-16 2003-03-01 Merck & Co Inc Compuestos azaciclohexapeptidicos.
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
EP0805685B1 (en) * 1995-01-26 2001-09-26 Merck & Co., Inc. Novel antifungal cyclohexapeptides
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EP0862579A1 (en) * 1995-11-09 1998-09-09 Merck & Co., Inc. Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use
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USRE38984E1 (en) * 1996-09-12 2006-02-14 Merck & Co., Inc. Antifungal combination therapy
US5854212A (en) * 1996-10-23 1998-12-29 Merck & Co., Inc. Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use
US5936062A (en) * 1997-06-12 1999-08-10 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
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EP2340846A1 (en) 2006-07-26 2011-07-06 Sandoz Ag Caspofungin formulations
TW200826957A (en) * 2006-10-16 2008-07-01 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Purification processes for echinocandin-type compounds
CA2692053A1 (en) * 2007-06-26 2008-12-31 Merck Sharp & Dohme Corp. Lyophilized anti-fungal composition
US20090075870A1 (en) * 2007-09-17 2009-03-19 Protia, Llc Deuterium-enriched caspofungin
WO2009142761A1 (en) * 2008-05-21 2009-11-26 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Caspofungin bo free of caspofungin co
US8048853B2 (en) 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
KR20110011704A (ko) * 2008-06-25 2011-02-08 테바 기오기스제르갸르 자르트쾨렌 뮈쾨되 레스즈베니타르사사그 카스포펀진 불순물 ａ를 함유하지 않는 카스포펀진
EP2240507A2 (en) * 2008-06-25 2010-10-20 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Processes for preparing high purity aza cyclohexapeptides
WO2010064219A1 (en) 2008-12-04 2010-06-10 Ranbaxy Laboratories Limited Process for the preparation of a novel intermediate for caspofungin
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US20120190815A1 (en) * 2009-08-06 2012-07-26 Tianhui Xu Azacyclohexapeptide or its pharmaceutical acceptable salt, preparing method and use thereof
US8751760B2 (en) * 2009-10-01 2014-06-10 Dell Products L.P. Systems and methods for power state transitioning in an information handling system
CN101792486A (zh) * 2010-04-12 2010-08-04 浙江海正药业股份有限公司 一种合成醋酸卡泊芬净的方法
CN102219832B (zh) * 2010-04-15 2013-08-21 上海天伟生物制药有限公司 一种氮杂环六肽或其盐的纯化方法
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EP2623511B1 (en) * 2010-09-29 2016-04-06 Shanghai Techwell Biopharmaceutical Co., Ltd Process for purifying cyclic lipopeptide compounds or salts thereof
US8877777B2 (en) * 2010-09-30 2014-11-04 Shanghai Techwell Biopharmaceutical Co., Ltd. Process for purifying cyclolipopeptide compounds or the salts thereof
CN102367267B (zh) 2010-11-10 2013-09-04 上海天伟生物制药有限公司 一种卡泊芬净的制备方法
CN102367268B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其用途
CN102367269B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其制备方法和用途
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EP2661441A4 (en) * 2011-01-03 2015-04-08 Biocon Ltd PROCESS FOR THE PREPARATION OF ACETATE CASPOFUNGIN AND ITS INTERMEDIATES
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Also Published As

Publication number Publication date
DE69421639D1 (de) 1999-12-23
HUT73496A (en) 1996-08-28
SI9420013A (en) 1996-08-31
CA2118757A1 (en) 1994-09-17
NZ263360A (en) 1997-08-22
UA59329C2 (uk) 2003-09-15
DK0620232T3 (da) 2000-03-13
AU5783294A (en) 1994-09-22
HU211890A9 (en) 1995-12-28
KR100329693B1 (ko) 2002-08-14
NO318372B1 (no) 2005-03-14
KR960701092A (ko) 1996-02-24
CZ235895A3 (en) 1996-02-14
WO1994021677A1 (en) 1994-09-29
CZ286235B6 (cs) 2000-02-16
FI954327L (fi) 1995-09-14
HK1008674A1 (en) 1999-05-14
DE10299013I1 (de) 2003-01-23
FI954327A0 (fi) 1995-09-14
GR3031872T3 (en) 2000-02-29
HU217614B (hu) 2000-03-28
NL300076I1 (nl) 2002-03-01
JPH06321986A (ja) 1994-11-22
LV12574B (en) 2001-04-20
NO953648L (no) 1995-11-15
LV12574A (en) 2000-11-20
NO2005020I2 (no) 2008-12-01
HRP940161B1 (en) 2001-04-30
CA2118757C (en) 2002-05-14
CN1119441A (zh) 1996-03-27
DE69421639T2 (de) 2000-06-08
BG99999A (bg) 1996-04-30
JP2568474B2 (ja) 1997-01-08
NO2005020I1 (no) 2005-09-13
RU2122548C1 (ru) 1998-11-27
SK113695A3 (en) 1996-02-07
ZA941807B (en) 1994-10-13
IL108892A0 (en) 1994-06-24
EP0620232B1 (en) 1999-11-17
CN1098274C (zh) 2003-01-08
NO953648D0 (no) 1995-09-15
FI109542B (fi) 2002-08-30
SK282527B6 (sk) 2002-10-08
US5514650A (en) 1996-05-07
AU668804B2 (en) 1996-05-16
BG63047B1 (bg) 2001-02-28
ES2139043T3 (es) 2000-02-01
HRP940161A2 (en) 1996-08-31
EP0620232A1 (en) 1994-10-19
RO113246B1 (ro) 1998-05-29
ATE186736T1 (de) 1999-12-15
NL300076I2 (nl) 2002-04-02
SI9420013B (sl) 2002-12-31
BR1100273A (pt) 1999-10-13
DE10299013I2 (de) 2009-11-19
HU9502703D0 (en) 1995-11-28
US5792746A (en) 1998-08-11
PL179261B1 (pl) 2000-08-31
BR9406009A (pt) 1995-12-26
US5378804A (en) 1995-01-03
PL310634A1 (en) 1995-12-27
IL108892A (en) 1998-07-15

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