LU82797A1 - Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant - Google Patents

Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant Download PDF

Info

Publication number
LU82797A1
LU82797A1 LU82797A LU82797A LU82797A1 LU 82797 A1 LU82797 A1 LU 82797A1 LU 82797 A LU82797 A LU 82797A LU 82797 A LU82797 A LU 82797A LU 82797 A1 LU82797 A1 LU 82797A1
Authority
LU
Luxembourg
Prior art keywords
amino
benzoyl
phenylacetamide
radical
mole
Prior art date
Application number
LU82797A
Other languages
English (en)
French (fr)
Inventor
Dwight A Shamblee
James R Shanklin
David A Walsh
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of LU82797A1 publication Critical patent/LU82797A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU82797A 1979-09-26 1980-09-24 Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant LU82797A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26
US7886079 1979-09-26

Publications (1)

Publication Number Publication Date
LU82797A1 true LU82797A1 (fr) 1982-05-10

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
LU82797A LU82797A1 (fr) 1979-09-26 1980-09-24 Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant

Country Status (36)

Country Link
JP (1) JPS5657751A (ja)
KR (1) KR840000763B1 (ja)
AT (1) AT374170B (ja)
AU (1) AU532359B2 (ja)
BE (1) BE885393A (ja)
BR (1) BR8006042A (ja)
CA (1) CA1128512A (ja)
CH (1) CH646138A5 (ja)
CS (1) CS227012B2 (ja)
DE (1) DE3035688A1 (ja)
DK (1) DK154136C (ja)
EG (1) EG15020A (ja)
ES (2) ES495329A0 (ja)
FI (1) FI72967C (ja)
FR (1) FR2465710A1 (ja)
GB (1) GB2059963B (ja)
GR (1) GR70049B (ja)
HK (1) HK59383A (ja)
HU (1) HU183215B (ja)
IE (1) IE50268B1 (ja)
IL (1) IL60999A (ja)
IN (3) IN151313B (ja)
IT (1) IT1133823B (ja)
KE (1) KE3307A (ja)
LU (1) LU82797A1 (ja)
MX (1) MX7159E (ja)
NL (1) NL8005346A (ja)
NO (1) NO152128C (ja)
NZ (1) NZ195061A (ja)
PH (1) PH22628A (ja)
PL (1) PL128998B1 (ja)
PT (1) PT71839B (ja)
SE (1) SE448626B (ja)
SG (1) SG42983G (ja)
YU (3) YU41734B (ja)
ZA (1) ZA805476B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
PT1423168E (pt) 2001-09-03 2006-05-31 Newron Pharm Spa Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ2009367A3 (cs) * 2009-06-08 2010-06-16 Farmak, A.S. Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (ja) * 1967-07-31 1971-03-24
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GR70049B (ja) 1982-07-26
KE3307A (en) 1983-08-19
DK154136B (da) 1988-10-17
ES8200329A1 (es) 1981-10-16
HU183215B (en) 1984-04-28
DK405780A (da) 1981-03-27
FR2465710B1 (ja) 1984-10-12
IL60999A (en) 1984-05-31
YU43306B (en) 1989-06-30
IE801946L (en) 1981-03-26
YU73183A (en) 1983-12-31
JPS5657751A (en) 1981-05-20
NZ195061A (en) 1984-04-27
JPH0141616B2 (ja) 1989-09-06
BR8006042A (pt) 1981-04-07
ES8204715A1 (es) 1982-05-01
FI72967B (fi) 1987-04-30
IN151313B (ja) 1983-03-26
NL8005346A (nl) 1981-03-30
KR840000763B1 (ko) 1984-06-08
CH646138A5 (fr) 1984-11-15
NO152128B (no) 1985-04-29
FI72967C (fi) 1987-08-10
IL60999A0 (en) 1980-11-30
AU6211680A (en) 1981-04-02
YU41734B (en) 1987-12-31
ES503019A0 (es) 1982-05-01
HK59383A (en) 1983-12-02
AU532359B2 (en) 1983-09-29
NO152128C (no) 1985-08-07
PL128998B1 (en) 1984-03-31
GB2059963A (en) 1981-04-29
YU245080A (en) 1983-09-30
IT1133823B (it) 1986-07-24
FR2465710A1 (fr) 1981-03-27
EG15020A (en) 1985-03-31
YU73083A (en) 1983-12-31
IE50268B1 (en) 1986-03-19
DE3035688A1 (de) 1981-04-16
DK154136C (da) 1989-03-06
GB2059963B (en) 1983-04-20
SE8006668L (sv) 1981-03-27
YU43305B (en) 1989-06-30
MX7159E (es) 1987-12-02
ES495329A0 (es) 1981-10-16
FI803002A (fi) 1981-03-27
SG42983G (en) 1985-01-11
IN156254B (ja) 1985-06-08
IT8024948A0 (it) 1980-09-26
AT374170B (de) 1984-03-26
KR830004210A (ko) 1983-07-06
NO802834L (no) 1981-03-27
BE885393A (fr) 1981-01-16
PH22628A (en) 1988-10-28
PL226919A1 (ja) 1982-02-01
IN156255B (ja) 1985-06-08
PT71839B (en) 1981-06-25
PT71839A (en) 1980-10-01
DE3035688C2 (ja) 1990-05-17
CS227012B2 (en) 1984-04-16
ATA474580A (de) 1983-08-15
CA1128512A (en) 1982-07-27
SE448626B (sv) 1987-03-09
ZA805476B (en) 1981-11-25

Similar Documents

Publication Publication Date Title
PL154186B1 (en) Method for manufacturing arylic derivatives of the hydroxamic acid
CN115304593B (zh) 苯并异噻唑化合物及其药物组合物和应用
US5110831A (en) Vinylogous hydroxamic acids and derivatives thereof as 5-lipoxygenase inhibitors
LU82797A1 (fr) Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant
CH648283A5 (fr) Acides 2-amino-3-(alpha-hydroxybenzyl)-phenylacetiques et sels metalliques, esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant.
CH648285A5 (fr) Acides benzoyl-3-nitro-2-phenylacetiques et sels metalliques, amides et esters correspondants utiles notamment comme medicaments anti-inflammatoires, procede et composes pour leur preparation.
CH655924A5 (fr) Derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation, medicaments et compositions les renfermant.
JPH0122244B2 (ja)
FR2499981A1 (fr) Acides amino-2 halogenobenzoyl-3 methylphenylacetiques et leurs esters et sels utiles comme medicaments anti-inflammatoires et analgesiques
JPH0623152B2 (ja) N−〔〔5−(トリフルオロメチル)−6−メトキシ−1−ナフタレニル〕チオキソメチルまたはカルボニル〕−n−メチルグリシンアミド
JPS5883620A (ja) 薬剤としての4−フエニル−4−オキソ−2−ブテン酸のある種の誘導体及びそれを含有する組成物
CH449652A (fr) Procédé de préparation de nouvelles hydroxydiamines
US4520029A (en) Farnesene derivatives, mucosal stabilizing compositions and method of manufacturing the same
FR2465733A1 (fr) Nouveaux derives imidazolylethoxymethyliques de 1,3-dioxoloquinoleines utiles notamment comme medicaments antibacteriens et antifongiques, leur procede de preparation et compositions therapeutiques et formes pharmaceutiques les contenant
FR2624856A1 (en) Tromethamine salt of 1-methyl-ss-oxo- alpha -(phenylcarbamoyl)-2-pyrrolepropionitrile
CH641775A5 (fr) N-(1-methyl 2-pyrrolidinyl methyl) 2,3-dimethoxy 5-methylsulfamoyl benzamide et ses derives, son procede de preparation et composition le renferment.
FR2502619A1 (fr) Derives de la 1(2h)-isoquinolone et leurs utilisations therapeutiques notamment dans le traitement des ulceres
CH648295A5 (fr) Acides 2-amino-3-(alkylthiobenzyl)-phenylacetiques et leurs derives.
KR840001932B1 (ko) 2-(3,4,5-트리메톡시페닐)-4,5-이치환된 티아졸의 제조방법
EP0395526A1 (fr) Nouveaux dérivés benzothiazolinoniques, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
FR2581996A1 (fr) Nouveaux derives 6-substitues de 6h-dibenzo(b, d)thiopyranne utiles notamment immunomodulateurs et antiviraux et leur preparation
US4156009A (en) Diazepine derivatives
FR2632641A1 (fr) ((aryl-4-piperazinyl-1)-2 ethoxy)-3 p-cymene, les derives ortho, meta, para monosubstitues ou disubstitues sur le noyau phenyle dudit produit, le procede de preparation desdits derives, et les medicaments contenant lesdits composes comme principe actif
CA1306464C (en) 2-(3, 5-dimethyl-4-hydroxyphenyl)indole derivatives
KR100800561B1 (ko) 시부트라민 술포닐염의 제조방법 및 이를 포함하는비만관련 질환 예방 및 치료용 약학조성물