DK405780A - Analogifremgangsmaade til fremstilling af 2-amino-3-benzoylphenylacetamider og deres cycliske homologe - Google Patents

Analogifremgangsmaade til fremstilling af 2-amino-3-benzoylphenylacetamider og deres cycliske homologe

Info

Publication number
DK405780A
DK405780A DK405780A DK405780A DK405780A DK 405780 A DK405780 A DK 405780A DK 405780 A DK405780 A DK 405780A DK 405780 A DK405780 A DK 405780A DK 405780 A DK405780 A DK 405780A
Authority
DK
Denmark
Prior art keywords
benzoylphenylacetamides
homologist
analogy
cyclic
amino
Prior art date
Application number
DK405780A
Other languages
English (en)
Other versions
DK154136B (da
DK154136C (da
Inventor
J R Shanklin
D A Shamblee
D A Walsh
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of DK405780A publication Critical patent/DK405780A/da
Publication of DK154136B publication Critical patent/DK154136B/da
Application granted granted Critical
Publication of DK154136C publication Critical patent/DK154136C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
DK405780A 1979-09-26 1980-09-25 Analogifremgangsmaade til fremstilling af 2-amino-3-benzoylphenylacetamider DK154136C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26
US7886079 1979-09-26

Publications (3)

Publication Number Publication Date
DK405780A true DK405780A (da) 1981-03-27
DK154136B DK154136B (da) 1988-10-17
DK154136C DK154136C (da) 1989-03-06

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
DK405780A DK154136C (da) 1979-09-26 1980-09-25 Analogifremgangsmaade til fremstilling af 2-amino-3-benzoylphenylacetamider

Country Status (36)

Country Link
JP (1) JPS5657751A (da)
KR (1) KR840000763B1 (da)
AT (1) AT374170B (da)
AU (1) AU532359B2 (da)
BE (1) BE885393A (da)
BR (1) BR8006042A (da)
CA (1) CA1128512A (da)
CH (1) CH646138A5 (da)
CS (1) CS227012B2 (da)
DE (1) DE3035688A1 (da)
DK (1) DK154136C (da)
EG (1) EG15020A (da)
ES (2) ES8200329A1 (da)
FI (1) FI72967C (da)
FR (1) FR2465710A1 (da)
GB (1) GB2059963B (da)
GR (1) GR70049B (da)
HK (1) HK59383A (da)
HU (1) HU183215B (da)
IE (1) IE50268B1 (da)
IL (1) IL60999A (da)
IN (3) IN151313B (da)
IT (1) IT1133823B (da)
KE (1) KE3307A (da)
LU (1) LU82797A1 (da)
MX (1) MX7159E (da)
NL (1) NL8005346A (da)
NO (1) NO152128C (da)
NZ (1) NZ195061A (da)
PH (1) PH22628A (da)
PL (1) PL128998B1 (da)
PT (1) PT71839B (da)
SE (1) SE448626B (da)
SG (1) SG42983G (da)
YU (3) YU41734B (da)
ZA (1) ZA805476B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
US6066671A (en) 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
EP1423168B1 (en) 2001-09-03 2006-02-08 Newron Pharmaceuticals S.p.A. Pharmaceutical composition comprising gabapentin or an analogue thereof and an alpha-aminoamide and its analgesic use
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ301776B6 (cs) * 2009-06-08 2010-06-16 Farmak, A.S. Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (da) * 1967-07-31 1971-03-24
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ES495329A0 (es) 1981-10-16
HU183215B (en) 1984-04-28
CA1128512A (en) 1982-07-27
KR840000763B1 (ko) 1984-06-08
LU82797A1 (fr) 1982-05-10
BR8006042A (pt) 1981-04-07
ES8200329A1 (es) 1981-10-16
IT1133823B (it) 1986-07-24
PT71839B (en) 1981-06-25
ES503019A0 (es) 1982-05-01
HK59383A (en) 1983-12-02
FR2465710B1 (da) 1984-10-12
IE801946L (en) 1981-03-26
CH646138A5 (fr) 1984-11-15
KE3307A (en) 1983-08-19
NL8005346A (nl) 1981-03-30
ES8204715A1 (es) 1982-05-01
AU532359B2 (en) 1983-09-29
NZ195061A (en) 1984-04-27
AT374170B (de) 1984-03-26
YU41734B (en) 1987-12-31
NO802834L (no) 1981-03-27
ATA474580A (de) 1983-08-15
DE3035688C2 (da) 1990-05-17
YU245080A (en) 1983-09-30
IE50268B1 (en) 1986-03-19
FI72967C (fi) 1987-08-10
PH22628A (en) 1988-10-28
GB2059963A (en) 1981-04-29
SE448626B (sv) 1987-03-09
DE3035688A1 (de) 1981-04-16
CS227012B2 (en) 1984-04-16
IL60999A0 (en) 1980-11-30
IT8024948A0 (it) 1980-09-26
KR830004210A (ko) 1983-07-06
YU43306B (en) 1989-06-30
SE8006668L (sv) 1981-03-27
YU73183A (en) 1983-12-31
FI803002A (fi) 1981-03-27
JPH0141616B2 (da) 1989-09-06
IN156254B (da) 1985-06-08
YU73083A (en) 1983-12-31
AU6211680A (en) 1981-04-02
EG15020A (en) 1985-03-31
SG42983G (en) 1985-01-11
DK154136B (da) 1988-10-17
JPS5657751A (en) 1981-05-20
PL128998B1 (en) 1984-03-31
NO152128B (no) 1985-04-29
IN151313B (da) 1983-03-26
FR2465710A1 (fr) 1981-03-27
ZA805476B (en) 1981-11-25
DK154136C (da) 1989-03-06
YU43305B (en) 1989-06-30
GR70049B (da) 1982-07-26
PT71839A (en) 1980-10-01
FI72967B (fi) 1987-04-30
IL60999A (en) 1984-05-31
BE885393A (fr) 1981-01-16
NO152128C (no) 1985-08-07
GB2059963B (en) 1983-04-20
MX7159E (es) 1987-12-02
PL226919A1 (da) 1982-02-01
IN156255B (da) 1985-06-08

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