DK577377A - Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estere - Google Patents
Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estereInfo
- Publication number
- DK577377A DK577377A DK577377A DK577377A DK577377A DK 577377 A DK577377 A DK 577377A DK 577377 A DK577377 A DK 577377A DK 577377 A DK577377 A DK 577377A DK 577377 A DK577377 A DK 577377A
- Authority
- DK
- Denmark
- Prior art keywords
- gammalactarene
- calboarles
- 7xci
- 6xcy
- 17alfa
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK81779A DK81779A (da) | 1976-12-27 | 1979-02-26 | Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-brom eller chlor-17-hydroxy-3-oxo-17alfa-pregn-4-en21carboxylsyregamma-lactoner |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/754,136 US4069219A (en) | 1976-12-27 | 1976-12-27 | 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK577377A true DK577377A (da) | 1978-06-28 |
Family
ID=25033598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK577377A DK577377A (da) | 1976-12-27 | 1977-12-23 | Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estere |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4069219A (da) |
| JP (1) | JPS5382767A (da) |
| AU (1) | AU518862B2 (da) |
| BE (1) | BE862365A (da) |
| CA (1) | CA1099702A (da) |
| CH (6) | CH637403A5 (da) |
| DE (1) | DE2758279A1 (da) |
| DK (1) | DK577377A (da) |
| FI (1) | FI773936A7 (da) |
| FR (1) | FR2375253A1 (da) |
| GB (1) | GB1575986A (da) |
| IE (1) | IE46128B1 (da) |
| IL (1) | IL53692A (da) |
| NL (1) | NL7714428A (da) |
| NO (2) | NO774464L (da) |
| NZ (1) | NZ186119A (da) |
| PT (1) | PT67455B (da) |
| SE (1) | SE7714764L (da) |
| ZA (1) | ZA777684B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3111951A1 (de) * | 1981-03-23 | 1982-09-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 7(alpha)-alkoxycarbonyl-15ss-methylen-4-androstene, verfahren zu ihrer herstellung und verwendung als arzneimittel |
| JPS5921698A (ja) * | 1982-07-22 | 1984-02-03 | シエ−リング・アクチエンゲゼルシヤフト | １７α−プレグネ−４−エン−３−オキソ−２１−カルボン酸エステル、その製法およびこれを含有する抗アンドロゲン作用を有する医薬 |
| DE3330084A1 (de) * | 1983-08-17 | 1985-03-07 | Schering AG, 1000 Berlin und 4709 Bergkamen | 7(alpha)-alkoxycarbonyl-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone und deren 21-carbonsaeuresalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| DE69637140T2 (de) | 1995-12-11 | 2008-04-10 | G.D. Searle Llc, Chicago | Verfahren zur herstellung einer epoxy-verbindung |
| US8389687B2 (en) * | 2000-10-23 | 2013-03-05 | Shanbrom Technologies, Llc | Polyvinylpyrrolidone cryoprecipitate extraction of clotting factors |
| US7411006B2 (en) * | 2000-10-23 | 2008-08-12 | Shanbrom Technologies, Llc | Enhanced production of blood clotting factors and fibrin fabric |
| US7297716B2 (en) * | 2000-10-23 | 2007-11-20 | Shanbrom Technologies, Llc | Enhanced production of blood components, blood cells and plasma without freezing |
| DK1487859T3 (da) * | 2002-03-22 | 2008-10-06 | Pharmacia & Upjohn Co Llc | Fremstillingsmetoder til at fremstille Eplerenon |
| TW200407150A (en) * | 2002-11-06 | 2004-05-16 | Upjohn Co | Processes for preparing 7- carboxy substituted steroids |
| WO2004043986A1 (en) * | 2002-11-07 | 2004-05-27 | Pharmacia & Upjohn Company Llc | Processes for preparing c-7 substituted 5-androstenes |
| PT2527356T (pt) | 2005-07-21 | 2018-03-26 | Bayer Ip Gmbh | Processo para a produção de 3-oxo-pregn-4-eno-21,17-carbolactonas através da oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-diidroxiandrostanos |
| SI1746101T2 (sl) | 2005-07-21 | 2014-09-30 | Bayer Pharma Aktiengesellschaft | Postopek za pripravo 3-okso-pregn-4-en-21,17-karbolaktonov z oksidacijo 17-(3-hidroksipropil)-3,17-dihidroksiandrostanov brez uporabe kovine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE787940A (fr) * | 1971-08-25 | 1973-02-26 | Searle & Co | Nouveaux medicaments diuretiques et hypotenseurs et procede de leur preparation |
| GB1368006A (en) * | 1972-08-24 | 1974-09-25 | Searle & Co | 4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone |
| US3972871A (en) * | 1975-09-22 | 1976-08-03 | G. D. Searle & Co. | 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners |
-
1976
- 1976-12-27 US US05/754,136 patent/US4069219A/en not_active Expired - Lifetime
-
1977
- 1977-12-22 NZ NZ186119A patent/NZ186119A/xx unknown
- 1977-12-23 AU AU32012/77A patent/AU518862B2/en not_active Expired
- 1977-12-23 CA CA293,844A patent/CA1099702A/en not_active Expired
- 1977-12-23 DK DK577377A patent/DK577377A/da unknown
- 1977-12-23 GB GB53717/77A patent/GB1575986A/en not_active Expired
- 1977-12-26 FR FR7739218A patent/FR2375253A1/fr active Granted
- 1977-12-26 IL IL53692A patent/IL53692A/xx unknown
- 1977-12-26 PT PT67455A patent/PT67455B/pt unknown
- 1977-12-27 JP JP15852277A patent/JPS5382767A/ja active Pending
- 1977-12-27 CH CH1607777A patent/CH637403A5/de not_active IP Right Cessation
- 1977-12-27 NO NO774464A patent/NO774464L/no unknown
- 1977-12-27 DE DE19772758279 patent/DE2758279A1/de not_active Withdrawn
- 1977-12-27 FI FI773936A patent/FI773936A7/fi not_active Application Discontinuation
- 1977-12-27 BE BE183884A patent/BE862365A/xx not_active IP Right Cessation
- 1977-12-27 NL NL7714428A patent/NL7714428A/xx not_active Application Discontinuation
- 1977-12-27 SE SE7714764A patent/SE7714764L/xx unknown
- 1977-12-28 ZA ZA00777684A patent/ZA777684B/xx unknown
- 1977-12-29 IE IE2635/77A patent/IE46128B1/en unknown
-
1982
- 1982-01-11 NO NO820059A patent/NO820059L/no unknown
- 1982-05-18 CH CH310682A patent/CH637404A5/de not_active IP Right Cessation
- 1982-06-03 CH CH343682A patent/CH637408A5/de not_active IP Right Cessation
- 1982-06-03 CH CH343482A patent/CH637405A5/de not_active IP Right Cessation
- 1982-06-03 CH CH343582A patent/CH635595A5/de not_active IP Right Cessation
- 1982-11-15 CH CH665682A patent/CH638536A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU518862B2 (en) | 1981-10-22 |
| GB1575986A (en) | 1980-10-01 |
| AU3201277A (en) | 1979-06-28 |
| PT67455A (en) | 1978-01-01 |
| CH637408A5 (de) | 1983-07-29 |
| DE2758279A1 (de) | 1978-06-29 |
| IL53692A0 (en) | 1978-03-10 |
| IE46128B1 (en) | 1983-02-23 |
| US4069219A (en) | 1978-01-17 |
| NO774464L (no) | 1978-06-28 |
| BE862365A (fr) | 1978-06-27 |
| CA1099702A (en) | 1981-04-21 |
| CH637404A5 (de) | 1983-07-29 |
| PT67455B (en) | 1979-05-25 |
| ZA777684B (en) | 1979-08-29 |
| CH638536A5 (de) | 1983-09-30 |
| CH635595A5 (de) | 1983-04-15 |
| IE46128L (en) | 1978-06-27 |
| FR2375253B1 (da) | 1981-04-30 |
| CH637405A5 (de) | 1983-07-29 |
| FI773936A7 (fi) | 1978-06-28 |
| FR2375253A1 (fr) | 1978-07-21 |
| JPS5382767A (en) | 1978-07-21 |
| CH637403A5 (de) | 1983-07-29 |
| NZ186119A (en) | 1979-08-31 |
| NO820059L (no) | 1978-06-28 |
| NL7714428A (nl) | 1978-06-29 |
| SE7714764L (sv) | 1978-06-28 |
| IL53692A (en) | 1982-07-30 |
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