PT2527356T - Processo para a produção de 3-oxo-pregn-4-eno-21,17-carbolactonas através da oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-diidroxiandrostanos - Google Patents

Processo para a produção de 3-oxo-pregn-4-eno-21,17-carbolactonas através da oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-diidroxiandrostanos

Info

Publication number
PT2527356T
PT2527356T PT121654503T PT12165450T PT2527356T PT 2527356 T PT2527356 T PT 2527356T PT 121654503 T PT121654503 T PT 121654503T PT 12165450 T PT12165450 T PT 12165450T PT 2527356 T PT2527356 T PT 2527356T
Authority
PT
Portugal
Prior art keywords
dihydroxyandrostanes
carbolactones
pregn
ene
oxo
Prior art date
Application number
PT121654503T
Other languages
English (en)
Inventor
Seba Hartmut
Seilz Carsten
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37434272&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2527356(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP05090214.7A external-priority patent/EP1746101B2/de
Priority claimed from US11/185,984 external-priority patent/US7319154B2/en
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of PT2527356T publication Critical patent/PT2527356T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PT121654503T 2005-07-21 2006-07-20 Processo para a produção de 3-oxo-pregn-4-eno-21,17-carbolactonas através da oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-diidroxiandrostanos PT2527356T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05090214.7A EP1746101B2 (de) 2005-07-21 2005-07-21 Verfahren zur Herstellung von 3-Oxo-pregn-4-en-21,17-carbolactonen durch die metallfreie Oxidation von 17-(3-hydroxypropyl)-3,17-dihydroxyandrostanen
US11/185,984 US7319154B2 (en) 2005-07-21 2005-07-21 Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes

Publications (1)

Publication Number Publication Date
PT2527356T true PT2527356T (pt) 2018-03-26

Family

ID=37434272

Family Applications (2)

Application Number Title Priority Date Filing Date
PT121654503T PT2527356T (pt) 2005-07-21 2006-07-20 Processo para a produção de 3-oxo-pregn-4-eno-21,17-carbolactonas através da oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-diidroxiandrostanos
PT67627869T PT1910403T (pt) 2005-07-21 2006-07-20 Processo para a produção de 3-oxo-pregn-4-eno-21,17- carbolactonas através da oxidação isenta de metais de 17- (3-hidroxipropil)-3,17-diidroxiandrostanos

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT67627869T PT1910403T (pt) 2005-07-21 2006-07-20 Processo para a produção de 3-oxo-pregn-4-eno-21,17- carbolactonas através da oxidação isenta de metais de 17- (3-hidroxipropil)-3,17-diidroxiandrostanos

Country Status (23)

Country Link
EP (2) EP2527356B1 (pt)
KR (1) KR101410583B1 (pt)
AU (1) AU2006271885B8 (pt)
BR (1) BRPI0613679A2 (pt)
CA (1) CA2614804C (pt)
CR (1) CR9669A (pt)
DK (2) DK1910403T3 (pt)
EA (1) EA016411B1 (pt)
EC (1) ECSP088124A (pt)
ES (2) ES2663399T3 (pt)
HK (1) HK1120520A1 (pt)
HR (2) HRP20160853T1 (pt)
HU (2) HUE038504T2 (pt)
IL (1) IL188619A (pt)
LT (1) LT2527356T (pt)
MX (1) MX2008000936A (pt)
NO (1) NO344680B1 (pt)
NZ (1) NZ565247A (pt)
PL (2) PL2527356T3 (pt)
PT (2) PT2527356T (pt)
RS (2) RS54927B1 (pt)
SI (2) SI2527356T1 (pt)
WO (1) WO2007009821A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008137050A2 (en) 2007-05-01 2008-11-13 Sicor Inc. A process for preparing drospirenone and intermediate thereof
DE102007030596B3 (de) * 2007-06-28 2009-03-12 Bayer Schering Pharma Aktiengesellschaft Verfahren zur Herstellung von 17-(3-Hydroxypropyl)-17-hydroxysteroiden
EP2266998B1 (en) * 2009-06-16 2013-07-24 Crystal Pharma, S.A.U. Process for obtaining 17-spirolactones in steroids
CN102040650B (zh) * 2010-10-26 2014-03-26 西安科技大学 串联反应构建甾体-6β,7β-亚甲基结构的方法
ITMI20111383A1 (it) * 2011-07-25 2013-01-26 Ind Chimica Srl Processo per la preparazione di drospirenone

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069219A (en) 1976-12-27 1978-01-17 G. D. Searle & Co. 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters
DE3026783C2 (de) 1980-07-11 1982-07-29 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5β-Hydroxy-δ↑6↑-steroiden
DE3042136A1 (de) 1980-11-03 1982-06-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur herstellung von 3 (beta), 7 (beta) -dihydroxy- (delta) (pfeil hoch)5(pfeil hoch) -steroiden
EP0075189B1 (en) 1981-09-21 1985-08-28 Schering Aktiengesellschaft 3-beta,7-beta,15-alpha-trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and its preparation
DE19633685C1 (de) * 1996-08-12 1997-10-09 Schering Ag Verfahren zur Herstellung von Drospirenon (6beta,7beta;15 beta,16beta-Dimethyl-en-3-oxo-17alpha-pregn-4-en-21,17-carbolacton, DRSP) sowie 7alpha-(3-Hydroxy-1-propyl)-6beta,7beta;15beta, 16beta-dimethylen-5beta-androstan-3beta,5,17beta-triol (ZK 92836) und 6beta,7beta;15beta,16beta-dimethylen-5beta-hydroxy-3-oxo-17alpha-androstan-21,17-carbolacton (90965) als Zwischenprodukte des Verfahrens
WO2004016640A2 (en) * 2002-08-16 2004-02-26 Pharmacia & Upjohn Company Llc 5 ANDROSTEN-3β-OL STEROID INTERMEDIATES AND PROCESSES FOR THEIR PREPARATION
ITMI20040367A1 (it) * 2004-03-01 2004-06-01 Ind Chimica Srl Processo per la preparazione di drospirenone
ITMI20042338A1 (it) 2004-12-06 2005-03-06 Ind Chimica Srl Processo per la preparazione di drospirenone

Also Published As

Publication number Publication date
AU2006271885B2 (en) 2012-02-16
EP2527356A3 (en) 2014-04-09
SI1910403T1 (sl) 2016-08-31
ECSP088124A (es) 2008-02-20
HUE038504T2 (hu) 2018-10-29
LT2527356T (lt) 2018-04-10
HK1120520A1 (en) 2009-04-03
NO20080894L (no) 2008-04-21
ES2581735T3 (es) 2016-09-07
BRPI0613679A2 (pt) 2011-01-25
AU2006271885A8 (en) 2008-02-21
AU2006271885B8 (en) 2012-03-08
DK1910403T3 (en) 2016-08-01
EA016411B1 (ru) 2012-04-30
ES2663399T3 (es) 2018-04-12
HUE027858T2 (en) 2016-11-28
KR101410583B1 (ko) 2014-06-23
RS56982B1 (sr) 2018-05-31
EP1910403A1 (en) 2008-04-16
AU2006271885A1 (en) 2007-01-25
CA2614804A1 (en) 2007-01-25
EP1910403B1 (en) 2016-04-27
EP2527356A2 (en) 2012-11-28
CA2614804C (en) 2014-09-23
NZ565247A (en) 2011-02-25
NO344680B1 (no) 2020-03-02
DK2527356T3 (en) 2018-04-09
PT1910403T (pt) 2016-07-14
KR20080033428A (ko) 2008-04-16
WO2007009821A1 (en) 2007-01-25
EA200800326A1 (ru) 2008-08-29
IL188619A (en) 2016-06-30
HRP20160853T1 (hr) 2016-09-23
IL188619A0 (en) 2008-04-13
MX2008000936A (es) 2008-03-27
SI2527356T1 (en) 2018-04-30
HRP20180454T1 (hr) 2018-05-04
EP2527356B1 (en) 2018-01-03
CR9669A (es) 2008-02-20
PL2527356T3 (pl) 2018-06-29
RS54927B1 (sr) 2016-10-31
PL1910403T3 (pl) 2016-10-31

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