PT2527356T - Processo para a produção de 3-oxo-pregn-4-eno-21,17-carbolactonas através da oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-diidroxiandrostanos - Google Patents
Processo para a produção de 3-oxo-pregn-4-eno-21,17-carbolactonas através da oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-diidroxiandrostanosInfo
- Publication number
- PT2527356T PT2527356T PT121654503T PT12165450T PT2527356T PT 2527356 T PT2527356 T PT 2527356T PT 121654503 T PT121654503 T PT 121654503T PT 12165450 T PT12165450 T PT 12165450T PT 2527356 T PT2527356 T PT 2527356T
- Authority
- PT
- Portugal
- Prior art keywords
- dihydroxyandrostanes
- carbolactones
- pregn
- ene
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C07J53/008—3 membered carbocyclic rings in position 15/16
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05090214.7A EP1746101B2 (de) | 2005-07-21 | 2005-07-21 | Verfahren zur Herstellung von 3-Oxo-pregn-4-en-21,17-carbolactonen durch die metallfreie Oxidation von 17-(3-hydroxypropyl)-3,17-dihydroxyandrostanen |
US11/185,984 US7319154B2 (en) | 2005-07-21 | 2005-07-21 | Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2527356T true PT2527356T (pt) | 2018-03-26 |
Family
ID=37434272
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT67627869T PT1910403T (pt) | 2005-07-21 | 2006-07-20 | Processo para a produção de 3-oxo-pregn-4-eno-21,17- carbolactonas através da oxidação isenta de metais de 17- (3-hidroxipropil)-3,17-diidroxiandrostanos |
PT121654503T PT2527356T (pt) | 2005-07-21 | 2006-07-20 | Processo para a produção de 3-oxo-pregn-4-eno-21,17-carbolactonas através da oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-diidroxiandrostanos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT67627869T PT1910403T (pt) | 2005-07-21 | 2006-07-20 | Processo para a produção de 3-oxo-pregn-4-eno-21,17- carbolactonas através da oxidação isenta de metais de 17- (3-hidroxipropil)-3,17-diidroxiandrostanos |
Country Status (23)
Country | Link |
---|---|
EP (2) | EP2527356B1 (pt) |
KR (1) | KR101410583B1 (pt) |
AU (1) | AU2006271885B8 (pt) |
BR (1) | BRPI0613679A2 (pt) |
CA (1) | CA2614804C (pt) |
CR (1) | CR9669A (pt) |
DK (2) | DK1910403T3 (pt) |
EA (1) | EA016411B1 (pt) |
EC (1) | ECSP088124A (pt) |
ES (2) | ES2663399T3 (pt) |
HK (1) | HK1120520A1 (pt) |
HR (2) | HRP20160853T1 (pt) |
HU (2) | HUE038504T2 (pt) |
IL (1) | IL188619A (pt) |
LT (1) | LT2527356T (pt) |
MX (1) | MX2008000936A (pt) |
NO (1) | NO344680B1 (pt) |
NZ (1) | NZ565247A (pt) |
PL (2) | PL1910403T3 (pt) |
PT (2) | PT1910403T (pt) |
RS (2) | RS54927B1 (pt) |
SI (2) | SI2527356T1 (pt) |
WO (1) | WO2007009821A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0803102A2 (pt) | 2007-05-01 | 2011-11-01 | Sicor Inc | um processo para preparar drospirenona e intermediários da mesma |
DE102007030596B3 (de) * | 2007-06-28 | 2009-03-12 | Bayer Schering Pharma Aktiengesellschaft | Verfahren zur Herstellung von 17-(3-Hydroxypropyl)-17-hydroxysteroiden |
EP2266998B1 (en) * | 2009-06-16 | 2013-07-24 | Crystal Pharma, S.A.U. | Process for obtaining 17-spirolactones in steroids |
CN102040650B (zh) * | 2010-10-26 | 2014-03-26 | 西安科技大学 | 串联反应构建甾体-6β,7β-亚甲基结构的方法 |
ITMI20111383A1 (it) * | 2011-07-25 | 2013-01-26 | Ind Chimica Srl | Processo per la preparazione di drospirenone |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4069219A (en) | 1976-12-27 | 1978-01-17 | G. D. Searle & Co. | 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters |
DE3026783C2 (de) | 1980-07-11 | 1982-07-29 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von 5β-Hydroxy-δ↑6↑-steroiden |
DE3042136A1 (de) | 1980-11-03 | 1982-06-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur herstellung von 3 (beta), 7 (beta) -dihydroxy- (delta) (pfeil hoch)5(pfeil hoch) -steroiden |
DE3265852D1 (en) | 1981-09-21 | 1985-10-03 | Schering Ag | 3-beta,7-beta,15-alpha-trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and its preparation |
DE19633685C1 (de) * | 1996-08-12 | 1997-10-09 | Schering Ag | Verfahren zur Herstellung von Drospirenon (6beta,7beta;15 beta,16beta-Dimethyl-en-3-oxo-17alpha-pregn-4-en-21,17-carbolacton, DRSP) sowie 7alpha-(3-Hydroxy-1-propyl)-6beta,7beta;15beta, 16beta-dimethylen-5beta-androstan-3beta,5,17beta-triol (ZK 92836) und 6beta,7beta;15beta,16beta-dimethylen-5beta-hydroxy-3-oxo-17alpha-androstan-21,17-carbolacton (90965) als Zwischenprodukte des Verfahrens |
EP1534732B1 (en) * | 2002-08-16 | 2006-09-13 | Pharmacia & Upjohn Company LLC | 5 androsten-3-ol steroid intermediates and processes for their preparation |
ITMI20040367A1 (it) * | 2004-03-01 | 2004-06-01 | Ind Chimica Srl | Processo per la preparazione di drospirenone |
ITMI20042338A1 (it) * | 2004-12-06 | 2005-03-06 | Ind Chimica Srl | Processo per la preparazione di drospirenone |
-
2006
- 2006-07-20 ES ES12165450.3T patent/ES2663399T3/es active Active
- 2006-07-20 EP EP12165450.3A patent/EP2527356B1/en active Active
- 2006-07-20 CA CA2614804A patent/CA2614804C/en active Active
- 2006-07-20 WO PCT/EP2006/007287 patent/WO2007009821A1/en active Application Filing
- 2006-07-20 HU HUE12165450A patent/HUE038504T2/hu unknown
- 2006-07-20 RS RS20160541A patent/RS54927B1/sr unknown
- 2006-07-20 SI SI200632250T patent/SI2527356T1/en unknown
- 2006-07-20 BR BRPI0613679-6A patent/BRPI0613679A2/pt not_active Application Discontinuation
- 2006-07-20 PL PL06762786.9T patent/PL1910403T3/pl unknown
- 2006-07-20 EP EP06762786.9A patent/EP1910403B1/en active Active
- 2006-07-20 EA EA200800326A patent/EA016411B1/ru not_active IP Right Cessation
- 2006-07-20 AU AU2006271885A patent/AU2006271885B8/en active Active
- 2006-07-20 NZ NZ565247A patent/NZ565247A/en unknown
- 2006-07-20 PL PL12165450T patent/PL2527356T3/pl unknown
- 2006-07-20 ES ES06762786.9T patent/ES2581735T3/es active Active
- 2006-07-20 SI SI200632075A patent/SI1910403T1/sl unknown
- 2006-07-20 PT PT67627869T patent/PT1910403T/pt unknown
- 2006-07-20 HU HUE06762786A patent/HUE027858T2/en unknown
- 2006-07-20 MX MX2008000936A patent/MX2008000936A/es active IP Right Grant
- 2006-07-20 PT PT121654503T patent/PT2527356T/pt unknown
- 2006-07-20 KR KR1020087003999A patent/KR101410583B1/ko active IP Right Grant
- 2006-07-20 LT LTEP12165450.3T patent/LT2527356T/lt unknown
- 2006-07-20 RS RS20180312A patent/RS56982B1/sr unknown
- 2006-07-20 DK DK06762786.9T patent/DK1910403T3/en active
- 2006-07-20 DK DK12165450.3T patent/DK2527356T3/en active
-
2008
- 2008-01-07 IL IL188619A patent/IL188619A/en active IP Right Grant
- 2008-01-17 CR CR9669A patent/CR9669A/es unknown
- 2008-01-18 EC EC2008008124A patent/ECSP088124A/es unknown
- 2008-02-20 NO NO20080894A patent/NO344680B1/no unknown
- 2008-12-25 HK HK08113989.8A patent/HK1120520A1/xx unknown
-
2016
- 2016-07-12 HR HRP20160853TT patent/HRP20160853T1/hr unknown
-
2018
- 2018-03-16 HR HRP20180454TT patent/HRP20180454T1/hr unknown
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