SE7714764L - Sett att framstella 7epsilon-(alkoxikarbonyl)-6epsilon-alkyl/halo-17-hydroxi-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-gamma-laktoner och motsvarande 21-karboxylsyror samt estrar och salter derav - Google Patents

Sett att framstella 7epsilon-(alkoxikarbonyl)-6epsilon-alkyl/halo-17-hydroxi-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-gamma-laktoner och motsvarande 21-karboxylsyror samt estrar och salter derav

Info

Publication number
SE7714764L
SE7714764L SE7714764A SE7714764A SE7714764L SE 7714764 L SE7714764 L SE 7714764L SE 7714764 A SE7714764 A SE 7714764A SE 7714764 A SE7714764 A SE 7714764A SE 7714764 L SE7714764 L SE 7714764L
Authority
SE
Sweden
Prior art keywords
oxyles
alcoxic
7epsilon
6epsilon
17alfa
Prior art date
Application number
SE7714764A
Other languages
English (en)
Swedish (sv)
Inventor
R M Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of SE7714764L publication Critical patent/SE7714764L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001—Lactones
    • C07J21/003—Lactones at position 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
SE7714764A 1976-12-27 1977-12-27 Sett att framstella 7epsilon-(alkoxikarbonyl)-6epsilon-alkyl/halo-17-hydroxi-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-gamma-laktoner och motsvarande 21-karboxylsyror samt estrar och salter derav SE7714764L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/754,136 US4069219A (en) 1976-12-27 1976-12-27 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters

Publications (1)

Publication Number Publication Date
SE7714764L true SE7714764L (sv) 1978-06-28

Family

ID=25033598

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7714764A SE7714764L (sv) 1976-12-27 1977-12-27 Sett att framstella 7epsilon-(alkoxikarbonyl)-6epsilon-alkyl/halo-17-hydroxi-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-gamma-laktoner och motsvarande 21-karboxylsyror samt estrar och salter derav

Country Status (19)

Country Link
US (1) US4069219A (da)
JP (1) JPS5382767A (da)
AU (1) AU518862B2 (da)
BE (1) BE862365A (da)
CA (1) CA1099702A (da)
CH (6) CH637403A5 (da)
DE (1) DE2758279A1 (da)
DK (1) DK577377A (da)
FI (1) FI773936A (da)
FR (1) FR2375253A1 (da)
GB (1) GB1575986A (da)
IE (1) IE46128B1 (da)
IL (1) IL53692A (da)
NL (1) NL7714428A (da)
NO (2) NO774464L (da)
NZ (1) NZ186119A (da)
PT (1) PT67455B (da)
SE (1) SE7714764L (da)
ZA (1) ZA777684B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3111951A1 (de) * 1981-03-23 1982-09-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen 7(alpha)-alkoxycarbonyl-15ss-methylen-4-androstene, verfahren zu ihrer herstellung und verwendung als arzneimittel
JPS5921698A (ja) * 1982-07-22 1984-02-03 シエ−リング・アクチエンゲゼルシヤフト １７α−プレグネ−４−エン−３−オキソ−２１−カルボン酸エステル、その製法およびこれを含有する抗アンドロゲン作用を有する医薬
DE3330084A1 (de) * 1983-08-17 1985-03-07 Schering AG, 1000 Berlin und 4709 Bergkamen 7(alpha)-alkoxycarbonyl-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone und deren 21-carbonsaeuresalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EA009176B1 (ru) 1995-12-11 2007-12-28 Дж.Д.Серл Энд Ко. Способ получения 7-альфа-карбоксил-9,11-эпоксистероидов и промежуточных продуктов, используемых для их получения, и общий способ эпоксидирования по олефиновым двойным связям
US7297716B2 (en) * 2000-10-23 2007-11-20 Shanbrom Technologies, Llc Enhanced production of blood components, blood cells and plasma without freezing
US8389687B2 (en) * 2000-10-23 2013-03-05 Shanbrom Technologies, Llc Polyvinylpyrrolidone cryoprecipitate extraction of clotting factors
US7411006B2 (en) * 2000-10-23 2008-08-12 Shanbrom Technologies, Llc Enhanced production of blood clotting factors and fibrin fabric
CA2480151A1 (en) * 2002-03-22 2003-10-09 Pharmacia Corporation C-17 spirolactonization and 6,7 oxidation of steroids
CN1694897A (zh) * 2002-11-06 2005-11-09 法玛西亚普强责任有限公司 7－羧基取代的甾族化合物的制备方法
MXPA05004024A (es) * 2002-11-07 2005-06-08 Pharmacia & Upjohn Co Llc Procedimientos para preparar esteroides c-7 sustituidos.
PL1746101T5 (pl) 2005-07-21 2014-11-28 Bayer Pharma AG Sposób wytwarzania 3-oksopreg-4-eno-21,17-karbolaktonów drogą bezmetalowego utleniania 17-(3-hydroksypropylo-3,17-dihydroksyandrostanu
AU2006271885B8 (en) 2005-07-21 2012-03-08 Bayer Pharma Aktiengsellshaft Process for the production of 3-oxo-pregn-4-ene-21,17-carbolactones by the metal-free oxidation of 17-(3-hydroxypropyl)-3,17-dihydroxyandrostanes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787940A (fr) * 1971-08-25 1973-02-26 Searle & Co Nouveaux medicaments diuretiques et hypotenseurs et procede de leur preparation
GB1368006A (en) * 1972-08-24 1974-09-25 Searle & Co 4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone
US3972871A (en) * 1975-09-22 1976-08-03 G. D. Searle & Co. 6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

Also Published As

Publication number Publication date
CH637404A5 (de) 1983-07-29
DE2758279A1 (de) 1978-06-29
CH638536A5 (de) 1983-09-30
CH637405A5 (de) 1983-07-29
NO774464L (no) 1978-06-28
NZ186119A (en) 1979-08-31
NO820059L (no) 1978-06-28
PT67455B (en) 1979-05-25
ZA777684B (en) 1979-08-29
FR2375253A1 (fr) 1978-07-21
FI773936A (fi) 1978-06-28
IL53692A (en) 1982-07-30
IL53692A0 (en) 1978-03-10
CH635595A5 (de) 1983-04-15
IE46128L (en) 1978-06-27
BE862365A (fr) 1978-06-27
CA1099702A (en) 1981-04-21
PT67455A (en) 1978-01-01
FR2375253B1 (da) 1981-04-30
AU518862B2 (en) 1981-10-22
CH637408A5 (de) 1983-07-29
CH637403A5 (de) 1983-07-29
JPS5382767A (en) 1978-07-21
US4069219A (en) 1978-01-17
DK577377A (da) 1978-06-28
AU3201277A (en) 1979-06-28
NL7714428A (nl) 1978-06-29
GB1575986A (en) 1980-10-01
IE46128B1 (en) 1983-02-23

Similar Documents

Publication Publication Date Title
NL7711610A (nl) Heparine bevattende liposomen en werkwijze ter bereiding ervan.
SE432624B (sv) Sett och anordning for att efterarbeta relshuvudprofil
SE7713639L (sv) Mikrokapslar och sett att framstella desamma
SE7701268L (sv) Sett och anordning for bestemning av edelstenars kvalitet
SE7608988L (sv) Passiverade och kapslade halvledare samt sett att framstella dessa
SE7714764L (sv) Sett att framstella 7epsilon-(alkoxikarbonyl)-6epsilon-alkyl/halo-17-hydroxi-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-gamma-laktoner och motsvarande 21-karboxylsyror samt estrar och salter derav
SE7702267L (sv) Sett och anordning for astadkommande av inspenning av ett arbetsstyrcke
SE7702052L (sv) Sett att framstella 1-nitro-9-alkylaminoalkylaminoakridiner samt salter derav
JPS536863A (en) Method of making thickkfilm resistor that can be adjusted more desirably
SE7608562L (sv) Sett att framstella kernalkylerade flerkerniga fenoler och anvendning derav
SE7811582L (sv) Sett att framstella moranolin och n-metylmoranolin
PL198445A1 (pl) Srodek grzybobojczy i sposob wytwarzania nowych eterow oksymow
PL199670A1 (pl) Sposob wytwarzania dwuaminoalkoksybenzenow
PL200038A1 (pl) Sposob hodowli grzybow basidiomycetes
JPS52126931A (en) Method of backkfilling injection construction
SE7704058L (sv) Biologisk protes och sett for framstellning derav
SE7611400L (sv) Sett och anordning for framstellning av formdragna foremal av termoplast
SE7603944L (sv) Bergrum samt forfarande for att framstella detta
JPS52139579A (en) Producing method of case and the like
JPS531254A (en) Method of forming plastic
JPS536862A (en) Method of making thinnfilm resistor
SE7601704L (sv) 3-jodcefamer och 2-jodmetylpenamer och sett att framstella desamma
SU559771A1 (ru) Способ получени отливок
DK211977A (da) Pyrrolioner samt fremgangsmade til fremstilling deraf
JPS53777A (en) Producing method of case and the like