ATE317280T1 - Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung - Google Patents

Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung

Info

Publication number
ATE317280T1
ATE317280T1 AT02797573T AT02797573T ATE317280T1 AT E317280 T1 ATE317280 T1 AT E317280T1 AT 02797573 T AT02797573 T AT 02797573T AT 02797573 T AT02797573 T AT 02797573T AT E317280 T1 ATE317280 T1 AT E317280T1
Authority
AT
Austria
Prior art keywords
aminoamide
analogue
alpha
pharmaceutical composition
analgesic use
Prior art date
Application number
AT02797573T
Other languages
English (en)
Inventor
Patricia Salvati
Orietta Veneroni
Roberto Maj
Ruggero Fariello
Luca Benatti
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Application granted granted Critical
Publication of ATE317280T1 publication Critical patent/ATE317280T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02797573T 2001-09-03 2002-08-09 Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung ATE317280T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01121069 2001-09-03

Publications (1)

Publication Number Publication Date
ATE317280T1 true ATE317280T1 (de) 2006-02-15

Family

ID=8178510

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02797573T ATE317280T1 (de) 2001-09-03 2002-08-09 Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung

Country Status (20)

Country Link
US (2) US8084447B2 (de)
EP (1) EP1423168B1 (de)
JP (1) JP4350508B2 (de)
KR (1) KR100890875B1 (de)
CN (1) CN1274306C (de)
AT (1) ATE317280T1 (de)
AU (1) AU2002333374B2 (de)
BR (1) BRPI0212298B8 (de)
CA (1) CA2459470C (de)
DE (1) DE60209152T2 (de)
DK (1) DK1423168T3 (de)
ES (1) ES2253579T3 (de)
IL (2) IL160523A0 (de)
MX (1) MXPA04002009A (de)
NO (1) NO331298B1 (de)
NZ (1) NZ531586A (de)
PT (1) PT1423168E (de)
RU (1) RU2295337C2 (de)
SI (1) SI1423168T1 (de)
WO (1) WO2003020273A2 (de)

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SI1423168T1 (sl) 2001-09-03 2006-06-30 Newron Pharm Spa Farmacevtski sestavek, ki vsebuje gabapentin ali njegov analog in alfa-aminoamid, in njegova analgetska uporaba
EP1438956A1 (de) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-Aminoamidderivate die als Antimigränemittel nützlich sind
US20040209960A1 (en) * 2003-01-30 2004-10-21 Dynogen Pharmaceuticals, Inc. Methods of treating lower urinary tract disorders using sodium channell modulators
US20040248979A1 (en) * 2003-06-03 2004-12-09 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
ES2339021T3 (es) * 2003-08-25 2010-05-14 Newron Pharmaceuticals S.P.A. Derivados de alfa-aminoamida utiles como agentes antiinflamatorios.
EP1533302A1 (de) * 2003-11-21 2005-05-25 Newron Pharmaceuticals S.p.A. Histidinderivate
EP1557166A1 (de) 2004-01-21 2005-07-27 Newron Pharmaceuticals S.p.A. Alpha-aminoamidderivate für die Behandlung von Funktionsstörungen der niedrigen Harnwege
US20080096965A1 (en) * 2004-09-10 2008-04-24 Newron Pharmaceuticals S.P.A. (Halobenzyloxy) Benzylamino-Propanamides as Sodium and/or Calcium Channel Selective Modulators
WO2006122259A1 (en) * 2005-05-10 2006-11-16 Teva Pharmaceutical Industries Ltd. Optical resolution of 3-carbamoylmethyl-5-methyl hexanoic acid
CN100410242C (zh) * 2005-06-23 2008-08-13 江苏恩华药业股份有限公司 普瑞巴林中间体及其制备方法
WO2007035890A1 (en) 2005-09-19 2007-03-29 Teva Pharmaceutical Industries Ltd. An asymmetric synthesis of ( s ) - ( + ) -3- (aminomethyl) -5-methylhexanoic acid
EP1798236A1 (de) * 2005-12-13 2007-06-20 EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. Verfahren zur Herstellung von 3-Pyridyl-1-hydroxyethyliden-1,1- bisphosphosonsäure und Hydrate davon
EP1963280B1 (de) * 2005-12-22 2015-10-28 Newron Pharmaceuticals S.p.A. 2-phenylethylaminoderivate als calcium- und/oder natrium-kanalmodulatoren
DK2474521T3 (en) * 2006-06-19 2016-10-31 Newron Pharm Spa High-purity 2- [4- (3- and 2-fluorobenzyloxy) benzylamino] propanamides for use as pharmaceuticals and pharmaceutical formulations thus
DK2155663T3 (en) 2007-06-15 2018-01-22 Newron Pharm Spa SUBSTITUTED 2- [2- (PHENYL) ETHYLAMINO] ALKANAMIDE DERIVATIVES AND THEIR USE AS SODIUM AND / OR CALCIUM CHANNEL MODULATORS
KR101593627B1 (ko) 2007-12-11 2016-02-11 뉴론 파마슈티칼즈 에스. 피. 에이. 고순도의 ２­［４­（３­ 또는 ２­플루오로벤질옥시）벤질아미노］프로판아미드의 제조방법
WO2010099200A1 (en) 2009-02-24 2010-09-02 Nektar Therapeutics Oligomer-amino acid conjugates
NZ602648A (en) 2010-04-27 2014-10-31 Newron Pharm Spa Process for the production of ralfinamide methanesulfonate salts or their r-enantiomers
UA129837C2 (uk) * 2018-09-04 2025-08-20 Мінерва Ньюросаєнсиз, Інк. Способи застосування феноксипропіламінової сполуки для лікування болю
IT201900006602A1 (it) * 2019-05-07 2020-11-07 Acraf Composizione farmaceutica per il trattamento del dolore neuropatico
CN120025292B (zh) * 2025-01-06 2026-04-28 江苏海洋大学 一种具有协同镇痛作用的化合物及其药物组合物、制备方法和用途

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Also Published As

Publication number Publication date
WO2003020273A2 (en) 2003-03-13
JP2005504782A (ja) 2005-02-17
US20040248978A1 (en) 2004-12-09
MXPA04002009A (es) 2004-07-08
PT1423168E (pt) 2006-05-31
KR100890875B1 (ko) 2009-03-31
DE60209152D1 (de) 2006-04-20
US8710040B2 (en) 2014-04-29
JP4350508B2 (ja) 2009-10-21
CA2459470C (en) 2010-10-12
SI1423168T1 (sl) 2006-06-30
AU2002333374A2 (en) 2003-03-18
IL160523A (en) 2009-02-11
EP1423168A2 (de) 2004-06-02
NO331298B1 (no) 2011-11-21
US20120142777A1 (en) 2012-06-07
DK1423168T3 (da) 2006-05-15
RU2295337C2 (ru) 2007-03-20
NZ531586A (en) 2005-09-30
EP1423168B1 (de) 2006-02-08
AU2002333374B2 (en) 2007-03-22
BR0212298A (pt) 2004-09-14
BRPI0212298B1 (pt) 2015-11-03
ES2253579T3 (es) 2006-06-01
HK1070305A1 (en) 2005-06-17
US8084447B2 (en) 2011-12-27
CA2459470A1 (en) 2003-03-13
RU2004110041A (ru) 2005-03-10
KR20040034686A (ko) 2004-04-28
IL160523A0 (en) 2004-07-25
CN1274306C (zh) 2006-09-13
WO2003020273A3 (en) 2003-09-04
NO20040907L (no) 2004-05-14
DE60209152T2 (de) 2006-08-03
BRPI0212298B8 (pt) 2021-05-25
CN1556720A (zh) 2004-12-22

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