IL160523A0 - PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN alpha-AMINOAMIDE AND ITS ANALGESIC USE - Google Patents
PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN alpha-AMINOAMIDE AND ITS ANALGESIC USEInfo
- Publication number
- IL160523A0 IL160523A0 IL16052302A IL16052302A IL160523A0 IL 160523 A0 IL160523 A0 IL 160523A0 IL 16052302 A IL16052302 A IL 16052302A IL 16052302 A IL16052302 A IL 16052302A IL 160523 A0 IL160523 A0 IL 160523A0
- Authority
- IL
- Israel
- Prior art keywords
- aminoamide
- gabapentin
- analogue
- pharmaceutical composition
- alpha
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01121069 | 2001-09-03 | ||
PCT/EP2002/008910 WO2003020273A2 (en) | 2001-09-03 | 2002-08-09 | Pharmaceutical composition comprising gabapentin or an analogue thereof and an $g(a)-aminoamide and its analgesic use |
Publications (1)
Publication Number | Publication Date |
---|---|
IL160523A0 true IL160523A0 (en) | 2004-07-25 |
Family
ID=8178510
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16052302A IL160523A0 (en) | 2001-09-03 | 2002-08-09 | PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN alpha-AMINOAMIDE AND ITS ANALGESIC USE |
IL160523A IL160523A (en) | 2001-09-03 | 2004-02-23 | Pharmaceutical preparations containing gabapentin or pragabalin and alpha-aminoamide |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL160523A IL160523A (en) | 2001-09-03 | 2004-02-23 | Pharmaceutical preparations containing gabapentin or pragabalin and alpha-aminoamide |
Country Status (21)
Country | Link |
---|---|
US (2) | US8084447B2 (xx) |
EP (1) | EP1423168B1 (xx) |
JP (1) | JP4350508B2 (xx) |
KR (1) | KR100890875B1 (xx) |
CN (1) | CN1274306C (xx) |
AT (1) | ATE317280T1 (xx) |
AU (1) | AU2002333374B2 (xx) |
BR (1) | BRPI0212298B8 (xx) |
CA (1) | CA2459470C (xx) |
DE (1) | DE60209152T2 (xx) |
DK (1) | DK1423168T3 (xx) |
ES (1) | ES2253579T3 (xx) |
HK (1) | HK1070305A1 (xx) |
IL (2) | IL160523A0 (xx) |
MX (1) | MXPA04002009A (xx) |
NO (1) | NO331298B1 (xx) |
NZ (1) | NZ531586A (xx) |
PT (1) | PT1423168E (xx) |
RU (1) | RU2295337C2 (xx) |
SI (1) | SI1423168T1 (xx) |
WO (1) | WO2003020273A2 (xx) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
CA2370030C (en) | 1999-04-09 | 2007-08-14 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US8084447B2 (en) | 2001-09-03 | 2011-12-27 | Newron Pharmaceuticals S.P.A. | Pharmaceutical composition comprising gabapentin or an analogue thereof and an α-aminoamide and its analgesic use |
EP1438956A1 (en) * | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
WO2004066990A2 (en) * | 2003-01-30 | 2004-08-12 | Dynogen Pharmaceuticals, Inc. | Methods of treating lower urinary tract disorders using sodium channel modulators |
US20040248979A1 (en) * | 2003-06-03 | 2004-12-09 | Dynogen Pharmaceuticals, Inc. | Method of treating lower urinary tract disorders |
KR101233711B1 (ko) * | 2003-08-25 | 2013-02-18 | 뉴론 파마슈티칼즈 에스. 피. 에이. | 항염증제로서 유용한 알파-아미노아미드 유도체 |
EP1533302A1 (en) * | 2003-11-21 | 2005-05-25 | Newron Pharmaceuticals S.p.A. | Histidine derivatives |
EP1557166A1 (en) | 2004-01-21 | 2005-07-27 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders |
CA2577408C (en) * | 2004-09-10 | 2013-07-09 | Elena Barbanti | Use of (halobenzyloxy) benzylamino-propanamides for the manufacture of medicaments active as sodium and/or calcium channel selective modulators |
MX2007014129A (es) * | 2005-05-10 | 2008-01-11 | Teva Pharma | Resolucion optica del acido 3-carbamoilmetil-5-metil hexanoico. |
CN100410242C (zh) * | 2005-06-23 | 2008-08-13 | 江苏恩华药业股份有限公司 | 普瑞巴林中间体及其制备方法 |
WO2007035789A1 (en) | 2005-09-19 | 2007-03-29 | Teva Pharmaceutical Industries Ltd. | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the new synthesis of (s)-pregabalin |
EP1798236A1 (en) * | 2005-12-13 | 2007-06-20 | EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. | Process for the preparation of 3-pyridyl-1-hydroxyethylidene-1,1- biphosphonic acid and hydrated forms thereof |
PT1963280E (pt) * | 2005-12-22 | 2016-02-02 | Newron Pharm Spa | Derivados de 2-feniletilamino como cálcio e/ou moduladores do canal de sódio |
JP5240476B2 (ja) | 2006-06-19 | 2013-07-17 | ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー | 2−[4−(3−及び2−フルオロベンジルオキシ)ベンジルアミノ]プロパンアミドの製造方法 |
HUE038113T2 (hu) | 2007-06-15 | 2018-09-28 | Newron Pharm Spa | Helyettesített 2-[2-(fenil)-etilamino]-alkánamid-származékok és alkalmazásuk nátrium- és/vagy kalciumcsatorna-modulátorokként |
KR101709498B1 (ko) | 2007-12-11 | 2017-02-23 | 뉴론 파마슈티칼즈 에스. 피. 에이. | 고순도의 2[4(3 또는 2플루오로벤질옥시)벤질아미노]프로판아미드의 제조방법 |
EP2400989B1 (en) | 2009-02-24 | 2016-08-10 | Nektar Therapeutics | Gabapentin-peg conjugates |
DK2563355T3 (en) | 2010-04-27 | 2016-09-12 | Newron Pharm Spa | A process for the preparation of ralfinamide-methanesulphonate or R-enantiomers thereof. |
US11766430B2 (en) * | 2018-09-04 | 2023-09-26 | Minerva Neurosciences, Inc. | Methods of using a phenoxypropylamine compound to treat pain |
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CH480308A (de) | 1966-08-11 | 1969-10-31 | Ciba Geigy | Verfahren zur Herstellung von Thiosemicarbazid-Verbindungen |
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GB9512854D0 (en) | 1995-06-23 | 1995-08-23 | Wellcome Found | Novel formulation |
US5795864A (en) | 1995-06-27 | 1998-08-18 | Neurex Corporation | Stable omega conopetide formulations |
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US6372792B1 (en) * | 1996-04-26 | 2002-04-16 | Guy Chouinard | Method for treating anxiety, anxiety disorders and insomnia |
CN1094757C (zh) | 1996-07-24 | 2002-11-27 | 沃尼尔·朗伯公司 | 用于治疗疼痛的异丁基γ-氨基丁酸及其衍生物 |
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US6290986B1 (en) | 1996-10-24 | 2001-09-18 | Pharmaceutical Applications Associates, Llc | Method and composition for transdermal administration of pharmacologic agents |
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GB9727523D0 (en) * | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
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JP2002520286A (ja) | 1998-07-09 | 2002-07-09 | ワーナー−ランバート・カンパニー | Gaba類縁体及びカフェインを含んでなる組成物 |
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BR0008847A (pt) * | 1999-03-10 | 2001-12-26 | Warner Lambert Co | Composições analgésicas que compreendemcompostos antiepilépticos, e métodos de uso dasmesmas |
HUP0201314A3 (en) | 1999-03-26 | 2003-02-28 | Euro Celtique Sa | Aryl substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles, and the use thereof and pharmaceutical compositions containing them |
CA2370030C (en) * | 1999-04-09 | 2007-08-14 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
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NZ516743A (en) | 1999-08-04 | 2004-02-27 | Icagen Inc | Methods for treating or preventing pain and anxiety |
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US8084447B2 (en) | 2001-09-03 | 2011-12-27 | Newron Pharmaceuticals S.P.A. | Pharmaceutical composition comprising gabapentin or an analogue thereof and an α-aminoamide and its analgesic use |
EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
AR044007A1 (es) | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
EP1588704A1 (en) | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
CA2577408C (en) | 2004-09-10 | 2013-07-09 | Elena Barbanti | Use of (halobenzyloxy) benzylamino-propanamides for the manufacture of medicaments active as sodium and/or calcium channel selective modulators |
-
2002
- 2002-08-09 US US10/487,931 patent/US8084447B2/en active Active
- 2002-08-09 EP EP02797573A patent/EP1423168B1/en not_active Expired - Lifetime
- 2002-08-09 PT PT02797573T patent/PT1423168E/pt unknown
- 2002-08-09 CN CNB028185897A patent/CN1274306C/zh not_active Expired - Lifetime
- 2002-08-09 DE DE60209152T patent/DE60209152T2/de not_active Expired - Lifetime
- 2002-08-09 BR BRPI0212298A patent/BRPI0212298B8/pt not_active IP Right Cessation
- 2002-08-09 AT AT02797573T patent/ATE317280T1/de active
- 2002-08-09 AU AU2002333374A patent/AU2002333374B2/en not_active Expired
- 2002-08-09 DK DK02797573T patent/DK1423168T3/da active
- 2002-08-09 CA CA2459470A patent/CA2459470C/en not_active Expired - Lifetime
- 2002-08-09 KR KR1020047003189A patent/KR100890875B1/ko active IP Right Grant
- 2002-08-09 NZ NZ531586A patent/NZ531586A/en not_active IP Right Cessation
- 2002-08-09 WO PCT/EP2002/008910 patent/WO2003020273A2/en active IP Right Grant
- 2002-08-09 RU RU2004110041/15A patent/RU2295337C2/ru active
- 2002-08-09 JP JP2003524580A patent/JP4350508B2/ja not_active Expired - Lifetime
- 2002-08-09 MX MXPA04002009A patent/MXPA04002009A/es active IP Right Grant
- 2002-08-09 SI SI200230290T patent/SI1423168T1/sl unknown
- 2002-08-09 IL IL16052302A patent/IL160523A0/xx active IP Right Grant
- 2002-08-09 ES ES02797573T patent/ES2253579T3/es not_active Expired - Lifetime
-
2004
- 2004-02-23 IL IL160523A patent/IL160523A/en unknown
- 2004-03-02 NO NO20040907A patent/NO331298B1/no not_active IP Right Cessation
-
2005
- 2005-04-08 HK HK05102974A patent/HK1070305A1/xx not_active IP Right Cessation
-
2011
- 2011-12-07 US US13/313,627 patent/US8710040B2/en not_active Expired - Lifetime
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