DK405780A - METHOD OF ANALOGY FOR THE PREPARATION OF 2-AMINO-3-BENZOYLPHENYLACETAMIDES AND THEIR CYCLIC HOMOLOGIST - Google Patents

METHOD OF ANALOGY FOR THE PREPARATION OF 2-AMINO-3-BENZOYLPHENYLACETAMIDES AND THEIR CYCLIC HOMOLOGIST

Info

Publication number
DK405780A
DK405780A DK405780A DK405780A DK405780A DK 405780 A DK405780 A DK 405780A DK 405780 A DK405780 A DK 405780A DK 405780 A DK405780 A DK 405780A DK 405780 A DK405780 A DK 405780A
Authority
DK
Denmark
Prior art keywords
benzoylphenylacetamides
homologist
analogy
cyclic
amino
Prior art date
Application number
DK405780A
Other languages
Danish (da)
Other versions
DK154136B (en
DK154136C (en
Inventor
J R Shanklin
D A Shamblee
D A Walsh
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of DK405780A publication Critical patent/DK405780A/en
Publication of DK154136B publication Critical patent/DK154136B/en
Application granted granted Critical
Publication of DK154136C publication Critical patent/DK154136C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
DK405780A 1979-09-26 1980-09-25 ANALOGY PROCEDURE FOR PREPARING 2-AMINO-3-BENZOYLPHENYLACETAMIDES DK154136C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26
US7886079 1979-09-26

Publications (3)

Publication Number Publication Date
DK405780A true DK405780A (en) 1981-03-27
DK154136B DK154136B (en) 1988-10-17
DK154136C DK154136C (en) 1989-03-06

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
DK405780A DK154136C (en) 1979-09-26 1980-09-25 ANALOGY PROCEDURE FOR PREPARING 2-AMINO-3-BENZOYLPHENYLACETAMIDES

Country Status (36)

Country Link
JP (1) JPS5657751A (en)
KR (1) KR840000763B1 (en)
AT (1) AT374170B (en)
AU (1) AU532359B2 (en)
BE (1) BE885393A (en)
BR (1) BR8006042A (en)
CA (1) CA1128512A (en)
CH (1) CH646138A5 (en)
CS (1) CS227012B2 (en)
DE (1) DE3035688A1 (en)
DK (1) DK154136C (en)
EG (1) EG15020A (en)
ES (2) ES8200329A1 (en)
FI (1) FI72967C (en)
FR (1) FR2465710A1 (en)
GB (1) GB2059963B (en)
GR (1) GR70049B (en)
HK (1) HK59383A (en)
HU (1) HU183215B (en)
IE (1) IE50268B1 (en)
IL (1) IL60999A (en)
IN (3) IN151313B (en)
IT (1) IT1133823B (en)
KE (1) KE3307A (en)
LU (1) LU82797A1 (en)
MX (1) MX7159E (en)
NL (1) NL8005346A (en)
NO (1) NO152128C (en)
NZ (1) NZ195061A (en)
PH (1) PH22628A (en)
PL (1) PL128998B1 (en)
PT (1) PT71839B (en)
SE (1) SE448626B (en)
SG (1) SG42983G (en)
YU (3) YU41734B (en)
ZA (1) ZA805476B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
IL160523A0 (en) 2001-09-03 2004-07-25 Newron Pharm Spa PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN alpha-AMINOAMIDE AND ITS ANALGESIC USE
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ2009367A3 (en) * 2009-06-08 2010-06-16 Farmak, A.S. Process for preparing 2-amino-3-benzoylphenylacetamide (nepafenac) with minimum of by-products
CN112794809B (en) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (en) * 1967-07-31 1971-03-24
CH577461A5 (en) * 1975-08-13 1976-07-15 Robins Co Inc A H
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EG15020A (en) 1985-03-31
FR2465710B1 (en) 1984-10-12
KE3307A (en) 1983-08-19
JPS5657751A (en) 1981-05-20
FI803002A (en) 1981-03-27
IL60999A0 (en) 1980-11-30
LU82797A1 (en) 1982-05-10
GB2059963A (en) 1981-04-29
AU6211680A (en) 1981-04-02
PL128998B1 (en) 1984-03-31
AU532359B2 (en) 1983-09-29
BR8006042A (en) 1981-04-07
NZ195061A (en) 1984-04-27
YU73183A (en) 1983-12-31
SG42983G (en) 1985-01-11
PT71839A (en) 1980-10-01
FI72967C (en) 1987-08-10
KR840000763B1 (en) 1984-06-08
DE3035688A1 (en) 1981-04-16
CH646138A5 (en) 1984-11-15
IN156255B (en) 1985-06-08
ES495329A0 (en) 1981-10-16
GR70049B (en) 1982-07-26
IT8024948A0 (en) 1980-09-26
FR2465710A1 (en) 1981-03-27
NO152128C (en) 1985-08-07
HU183215B (en) 1984-04-28
ZA805476B (en) 1981-11-25
MX7159E (en) 1987-12-02
DK154136B (en) 1988-10-17
IL60999A (en) 1984-05-31
IN151313B (en) 1983-03-26
FI72967B (en) 1987-04-30
AT374170B (en) 1984-03-26
DK154136C (en) 1989-03-06
ES8200329A1 (en) 1981-10-16
CS227012B2 (en) 1984-04-16
JPH0141616B2 (en) 1989-09-06
YU43305B (en) 1989-06-30
NL8005346A (en) 1981-03-30
SE448626B (en) 1987-03-09
DE3035688C2 (en) 1990-05-17
KR830004210A (en) 1983-07-06
NO152128B (en) 1985-04-29
PT71839B (en) 1981-06-25
YU73083A (en) 1983-12-31
SE8006668L (en) 1981-03-27
IN156254B (en) 1985-06-08
YU41734B (en) 1987-12-31
ES503019A0 (en) 1982-05-01
HK59383A (en) 1983-12-02
IT1133823B (en) 1986-07-24
CA1128512A (en) 1982-07-27
GB2059963B (en) 1983-04-20
YU245080A (en) 1983-09-30
ES8204715A1 (en) 1982-05-01
ATA474580A (en) 1983-08-15
IE801946L (en) 1981-03-26
PL226919A1 (en) 1982-02-01
IE50268B1 (en) 1986-03-19
YU43306B (en) 1989-06-30
PH22628A (en) 1988-10-28
NO802834L (en) 1981-03-27
BE885393A (en) 1981-01-16

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