ES503019A0 - A PROCEDURE FOR PREPARING 2-AMINO-3-BENZOIL-PHENYLACETE-MIDAS AND CYCLIC APPROVALS - Google Patents

A PROCEDURE FOR PREPARING 2-AMINO-3-BENZOIL-PHENYLACETE-MIDAS AND CYCLIC APPROVALS

Info

Publication number
ES503019A0
ES503019A0 ES503019A ES503019A ES503019A0 ES 503019 A0 ES503019 A0 ES 503019A0 ES 503019 A ES503019 A ES 503019A ES 503019 A ES503019 A ES 503019A ES 503019 A0 ES503019 A0 ES 503019A0
Authority
ES
Spain
Prior art keywords
phenylacete
benzoil
midas
approvals
cyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES503019A
Other languages
Spanish (es)
Other versions
ES8204715A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of ES503019A0 publication Critical patent/ES503019A0/en
Publication of ES8204715A1 publication Critical patent/ES8204715A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES503019A 1979-09-26 1981-06-12 2-Amino-3-benzoyl- phenylacetamides and cyclic homologues Expired ES8204715A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26

Publications (2)

Publication Number Publication Date
ES503019A0 true ES503019A0 (en) 1982-05-01
ES8204715A1 ES8204715A1 (en) 1982-05-01

Family

ID=22146633

Family Applications (2)

Application Number Title Priority Date Filing Date
ES495329A Granted ES495329A0 (en) 1979-09-26 1980-09-25 A PROCEDURE FOR PREPARING 2-AMINO-3-BENZOIL-PHENYLACETE-MIDAS AND CYCLIC APPROVALS
ES503019A Expired ES8204715A1 (en) 1979-09-26 1981-06-12 2-Amino-3-benzoyl- phenylacetamides and cyclic homologues

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES495329A Granted ES495329A0 (en) 1979-09-26 1980-09-25 A PROCEDURE FOR PREPARING 2-AMINO-3-BENZOIL-PHENYLACETE-MIDAS AND CYCLIC APPROVALS

Country Status (36)

Country Link
JP (1) JPS5657751A (en)
KR (1) KR840000763B1 (en)
AT (1) AT374170B (en)
AU (1) AU532359B2 (en)
BE (1) BE885393A (en)
BR (1) BR8006042A (en)
CA (1) CA1128512A (en)
CH (1) CH646138A5 (en)
CS (1) CS227012B2 (en)
DE (1) DE3035688A1 (en)
DK (1) DK154136C (en)
EG (1) EG15020A (en)
ES (2) ES495329A0 (en)
FI (1) FI72967C (en)
FR (1) FR2465710A1 (en)
GB (1) GB2059963B (en)
GR (1) GR70049B (en)
HK (1) HK59383A (en)
HU (1) HU183215B (en)
IE (1) IE50268B1 (en)
IL (1) IL60999A (en)
IN (3) IN151313B (en)
IT (1) IT1133823B (en)
KE (1) KE3307A (en)
LU (1) LU82797A1 (en)
MX (1) MX7159E (en)
NL (1) NL8005346A (en)
NO (1) NO152128C (en)
NZ (1) NZ195061A (en)
PH (1) PH22628A (en)
PL (1) PL128998B1 (en)
PT (1) PT71839B (en)
SE (1) SE448626B (en)
SG (1) SG42983G (en)
YU (3) YU41734B (en)
ZA (1) ZA805476B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
US8084447B2 (en) 2001-09-03 2011-12-27 Newron Pharmaceuticals S.P.A. Pharmaceutical composition comprising gabapentin or an analogue thereof and an α-aminoamide and its analgesic use
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ2009367A3 (en) * 2009-06-08 2010-06-16 Farmak, A.S. Process for preparing 2-amino-3-benzoylphenylacetamide (nepafenac) with minimum of by-products
CN112794809B (en) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (en) * 1967-07-31 1971-03-24
SE400966B (en) * 1975-08-13 1978-04-17 Robins Co Inc A H PROCEDURE FOR PREPARING 2-AMINO-3- (OR 5-) BENZOYL-PHENYLETIC ACIDS
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FI72967B (en) 1987-04-30
DK405780A (en) 1981-03-27
JPH0141616B2 (en) 1989-09-06
JPS5657751A (en) 1981-05-20
GB2059963A (en) 1981-04-29
NO152128C (en) 1985-08-07
IE50268B1 (en) 1986-03-19
YU245080A (en) 1983-09-30
IE801946L (en) 1981-03-26
SE8006668L (en) 1981-03-27
GR70049B (en) 1982-07-26
IN156255B (en) 1985-06-08
MX7159E (en) 1987-12-02
FR2465710B1 (en) 1984-10-12
SG42983G (en) 1985-01-11
PT71839A (en) 1980-10-01
HU183215B (en) 1984-04-28
NZ195061A (en) 1984-04-27
BE885393A (en) 1981-01-16
GB2059963B (en) 1983-04-20
NO802834L (en) 1981-03-27
CS227012B2 (en) 1984-04-16
HK59383A (en) 1983-12-02
AU532359B2 (en) 1983-09-29
DE3035688C2 (en) 1990-05-17
ES8200329A1 (en) 1981-10-16
ATA474580A (en) 1983-08-15
SE448626B (en) 1987-03-09
IT1133823B (en) 1986-07-24
YU43305B (en) 1989-06-30
FR2465710A1 (en) 1981-03-27
KR840000763B1 (en) 1984-06-08
YU73083A (en) 1983-12-31
CA1128512A (en) 1982-07-27
CH646138A5 (en) 1984-11-15
PH22628A (en) 1988-10-28
NO152128B (en) 1985-04-29
YU41734B (en) 1987-12-31
YU43306B (en) 1989-06-30
BR8006042A (en) 1981-04-07
AU6211680A (en) 1981-04-02
ES495329A0 (en) 1981-10-16
YU73183A (en) 1983-12-31
DE3035688A1 (en) 1981-04-16
IN156254B (en) 1985-06-08
PT71839B (en) 1981-06-25
IT8024948A0 (en) 1980-09-26
ZA805476B (en) 1981-11-25
IL60999A (en) 1984-05-31
IL60999A0 (en) 1980-11-30
PL128998B1 (en) 1984-03-31
KR830004210A (en) 1983-07-06
FI803002A (en) 1981-03-27
EG15020A (en) 1985-03-31
DK154136B (en) 1988-10-17
FI72967C (en) 1987-08-10
KE3307A (en) 1983-08-19
ES8204715A1 (en) 1982-05-01
NL8005346A (en) 1981-03-30
AT374170B (en) 1984-03-26
DK154136C (en) 1989-03-06
LU82797A1 (en) 1982-05-10
IN151313B (en) 1983-03-26
PL226919A1 (en) 1982-02-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506